A clinical trial evaluates the effect of pomegranate extract as a mouth wash for gingivitis in type 2 diabetic patients by Shayma Ghazi, Dilyar Ahmed Baban, Saif Monem Aziz

“…Patients and Methods: A randomized controlled clinical trial on 45 (T2DM) patients, both sexes with moderate gingivitis, age 40-55 years, (Hb1Ac) < 7%. …”
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Zinc Acetate Hydrate Supplementation versus Polaprezinc Supplementation for Improving Hypozincemia in Hemodialysis Patients: A Randomized Clinical Trial by Etsuko Kumagai, Kazuhiro Furumachi, Akihiro Kurihara, Ken Hosokawa, Keiko Hosohata, Shinji Takai

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Evaluation of Safety and Efficacy of a Single Lorecivivint Injection in Patients with Knee Osteoarthritis: A Multicenter, Observational Extension Trial by Christopher J. Swearingen, Jeyanesh R. S. Tambiah, Ismail Simsek, Heli Ghandehari, Sarah Kennedy, Yusuf Yazici

“…The objective of this trial was to evaluate long-term safety of LOR within an observational extension of two phase 2 trials. …”
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Effects of home-based virtual reality upper extremity rehabilitation in persons with chronic stroke: a randomized controlled trial by Hiroyuki Ase, Kaoru Honaga, Mami Tani, Tomokazu Takakura, Futoshi Wada, Yuhei Murakami, Reina Isayama, Akira Tanuma, Toshiyuki Fujiwara

“…Methods This was a single-blind, randomized, controlled trial conducted at two centers. The subjects were 14 outpatients with chronic stroke more than 6 months after the onset of the stroke. …”
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Comment on “Total Pancreatectomy With Islet Autotransplantation as an Alternative to High-Risk Pancreatojejunostomy After Pancreaticoduodenectomy: A Prospective Randomized Trial” by Leo Buhler, MD, Ty Dunn, MD, Ugo Boggi, MD, Charles Vollmer, MD, Jens Werner, MD, Christos Dervenis, MD, Giovanni Marchegiani, MD, Shailesh V. Shrikhande, MD, Igor Khatkov, MD, Abraham Fingerhut, MD

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First-time use of electronic patient-reported outcome measures in a cluster randomized trial: a qualitative study by Terese Solvoll Skåre, Tonje Lundeby, Jo Åsmund Lund, Marianne Jensen Hjermstad, May Helen Midtbust

“…Interviews elucidated their experiences of barriers and facilitators when implementing Eir through a cluster randomized trial. Data were analysed according to Framework Analysis, using both an inductive and deductive approach. …”
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Effect of Nebulized Morphine on Dyspnea of Mustard Gas-Exposed Patients: A Double-Blind Randomized Clinical Trial Study by Majid Shohrati, Mostafa Ghanei, Asghar Amini Harandi, Soniya Foroghi, Ali Amini Harandi

“…In a double-blind clinical trial study, 40 patients with documented history of exposure to SM were allocated to two groups: group 1 who received 1 mg morphine sulfate diluted by 4 cc normal saline 0.5% using nebulizer once daily for 5 days and group 2 serving as control who received normal saline as placebo. …”
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Comparison of the Effects of Vitagnus, Soy, and Vitagnus-soy Capsules on Premenstrual Syndrome in University Students: A Randomized Clinical Trial by Roya Partovi Golshan, Maryam Moradi, Hasan Rakhshandeh, Vahid Ghavami, Seyed Mostafa Moshirian Farahi

“…This study aimed to compare the effects of the Vitagnus, soy, and Vitagnus-soy combination on PMS in students.Methods: This triple-blind, three-arm clinical trial was conducted on 108 students with PMS living in the dormitory of Mashhad University of Medical Sciences from September 2022 to October 2023. …”
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Effect of Genicular Nerve Block (GNB) on Pain in Lesions of the Knee Joint: A Meta-Analysis of Randomized Controlled Trials by Li W, Xu F, Chen F, Cao L, Bao X

“…Computerized searches of randomized controlled trials were conducted in PubMed, EMbase, Cochrane Library, and Web of Science, with a search time frame until January 2024. …”
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Low Resolution Limits and Inaccurate Algorithms Decrease Significantly the Value of Late Loss in Current Drug-Eluting Stent Trials by Johannes B. Dahm, Frank van Buuren

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Measured Resection as Gap Balance Method in Mobile‐Bearing Medial Unicompartmental Knee Arthroplasty: A Randomized Controlled Trial by Qian Liu, Jianhua Ren, Wenhui Zhang, Tangzhao Liang, Zhe Wang, Siwei Xie, Yuhang Li, Jianfeng Hou, Kun Wang, Ronghan He

“…Conclusions The measured resection method is a reliable method for assisting surgeons in choosing the ideal meniscal bearing thickness in MB‐UKA to achieve proper gap balance and gain better clinical outcomes. Trial Registration ClinicalTrials.gov (NCT03815448)…”
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A Randomized Placebo-Controlled N-of-1 Trial: The Effect of Proton Pump Inhibitor in the Management of Gastroesophageal Reflux Disease by Fernando Sierra-Arango, D. M. Castaño, Jennifer D. Forero, Erika D. Pérez-Riveros, Gerardo Ardila Duarte, Maria L. Botero, Andres Cárdenas, Jose De la Hoz-Valle

“…However, recurrent reflux despite initial treatment is frequent. N-of-1 trial is a study that allows the identification of the best treatment for each patient. …”
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Cardiac function and quality of life improvement with fasudil hydrochloride in patients with diabetes post-PCI: a randomized controlled trial by Xuejia Yang, Qian Li, Yaning Liu, Ran Chen, Yanjing Liu, Chenghui Sun, Licha Kong, Qiuli Dong

“…Methods We conducted a randomized controlled trial including 100 patients with diabetes and CHD who underwent PCI. …”
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Different exercise interventions on quality of sleep in breast cancer survivors—a network meta-analysis of randomized controlled trials by Qi Song, Qi Song, You-kang Zhu, You-kang Zhu, Hai Liu, Hai Liu, Xiao Liu, Xiao Liu, Zhang-dong Jiang, Yu-jia Wang, Yu-jia Wang, Li-yun Xue, Li-yun Xue, Shao-ying Yang, Shao-ying Yang, Xi-fang Liu

“…The review was pre-registered (PROSPERO ID: CRD42023442892).ResultsData on 3083 breast cancer survivors with sleep disturbances from 34 eligible randomized controlled trials were analyzed, with 23 classified as medium risk and 2 as high risk. …”
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Masticatory Ability for a Single Implant Mandibular Overdenture Retained by Two Different Attachments: A Randomized Controlled Trial by Marwa Abdel AaL, Amr Naguib, Ahmed Salah, Karim Foda, Nora Sheta, Nouran Abdel Nabi

“…The aim of this randomized clinical trial was to compare the masticatory ability subjectively between ball and Cendres+Métaux Locator (CM-LOC) attachment for a single implant retained mandibular overdenture throughout a 24-month follow-up period. …”
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Effect of sealant versus fluoride varnish on dental caries incidence in Mexican children: A randomized controlled clinical trial by Miguel Ánge Fernández-Barrera, Edith Lara-Carrillo, Rogelio José Scougall-Vilchis, América Patricia Pontigo-Loyola, Mariana Mora-Acosta, Gladys Remigia Acuña-Gonzalez, Juan Alejandro Casanova-Sarmiento, Mauricio Escoffié-Ramírez, Carlo Eduardo Medina-Solis, Gerardo Maupomé

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Physical Activity, Fatigue, and Sleep in People with Parkinson’s Disease: A Secondary per Protocol Analysis from an Intervention Trial by S. Coe, M. Franssen, J. Collett, D. Boyle, A. Meaney, R. Chantry, P. Esser, H. Izadi, H. Dawes

“…PwP randomised into either an exercise group (29; 16 males, 13 females; mean age 67 years (7.12)) or a control handwriting group (36; 19 males; 17 females; mean age 67 years (5.88)) as part of a larger trial were included in this substudy if they had completed a 6-month weekly exercise programme (intervention group) and had complete objective physical activity data (intervention and control group). …”
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Reduction of Hepatic Fat Content by Dulaglutide for the Treatment of Diabetes Mellitus: A Two‐Centre Open, Single‐Arm Trial by Chuanfeng Liu, Yu Xin, Yajing Huang, Lili Xu, Ruizhi Zhou, Yangang Wang, Wei Wang

“…However, the relationship between quantitative reduction in hepatic fat content and improvement of pancreatic islet function by GLP‐1RA is unclear. Methods This trial was a single‐arm open cohort study. A total of 38 patients with T2DM and NAFLD were enrolled in the GLP‐1RA treatment group. …”
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The Effects of Three Methods of Luteal Phase Support on Pregnancy Outcomes in Poor Ovarian Responders: A Randomized Clinical Trial by Tahereh Madani, Arezoo Arabipoor, Fariba Ramezanali, Shabnam Khodabakhshi, Zahra Zolfaghary

Subjects: “…randomized controlled trials…”
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Efficacy of preoperative pulmonary rehabilitation in lung cancer patients: a systematic review and meta-analysis of randomized controlled trials by Yalun Guo, Mengdie Pan, Meidi Xiong, Miao Liu, Na Zhu, Haoxu Dong, Chunhua Zhang

“…Therefore, an updated meta-analysis is needed to integrate the latest published randomized controlled clinical trials (RCT). This updated analysis was performed to identify the clinical effects of preoperative pulmonary rehabilitation on physical rehabilitation (lung function, activity endurance, and dyspnea), psychological rehabilitation, quality of life, length of hospital stay, and postoperative pulmonary complications in patients with lung cancer. …”
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