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8161
Prevalence of post-acute sequelae of SARS-CoV-2 infection in people living with HIV: a systematic review with meta-analysisResearch in context
Published 2025-01-01“…Reviews, case reports, randomised control trials and editorials were excluded. The search was conducted without language restrictions. …”
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8162
Effects of exercise interventions on fatigue of hematopoietic stem cell transplantation patients: A Meta-analysis (运动干预对造血干细胞移植患者疲乏影响的Meta分析)...
Published 2024-06-01“…Methods Randomized controlled trials on exercise intervention in patients with HSCT were retrieved from Cochrane library, PubMed, Web of Science, Embase, CINAHL, CNKI, Wanfang Data, VIP, and CBM databases from the establishment to February 2024; ReMan 5. 3 software was used for meta-analysis. …”
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8163
Interventions used to reduce infectious aerosol concentrations in hospitals—a reviewResearch in context
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8164
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8165
Real-world ePRO use and clinical outcomes using electronic patient-reported symptom monitoring for patients with advanced non-small-cell lung cancer receiving first-line pembrolizu...
Published 2025-01-01“…Conclusion: Notwithstanding the null findings of this study, positive results of ePRO use in clinical trials and observational studies support the treatment-related symptom monitoring and survival benefits of ePRO utilization.…”
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8166
Perancangan Perangkat Audit Internal untuk Sistem Keamanan Informasi pada Organisasi XYZ
Published 2020-05-01“…The results of implementation trials, assessment, and finalization of our audit tool shows that our audit tool has been consistent with the needs of XYZ organization. …”
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8168
Impact of Online Interactive Decision Tools on Women’s Decision-Making Regarding Breast Cancer Screening: Systematic Review and Meta-Analysis
Published 2025-01-01“…We conducted meta-analyses on the identified randomized controlled trials, which were assessed using the revised Cochrane Risk of Bias 2 (RoB 2) tool. …”
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8169
Direct anterior approach (DAA) vs. conventional approaches in total hip arthroplasty: A RCT meta-analysis with an overview of related meta-analyses.
Published 2021-01-01“…Our aim was to draw definitive conclusions by conducting both a fixed and random model meta-analysis of quality randomized controlled trials (RCTs) and by comparison with related meta-analyses.…”
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8170
Efficacy and safety of PD-1 inhibitors as second-line treatment for advanced squamous esophageal cancer: a systematic review and network meta-analysis with a focus on PD-L1 express...
Published 2025-01-01“…To ensure transparency, novelty, and reliability, this study was prospectively registered in the systematic review registry (CRD42024540581).ResultsFive randomized controlled trials (RCTs), encompassing 2,078 patients and six treatment regimens, were included in this study. …”
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8171
Efficacy and safety of gut microbiome-targeted treatment in patients with depression: a systematic review and meta-analysis
Published 2025-01-01“…Methods We searched PubMed, Embase, Cochrane Library, Web of Science, and the Chinese National Knowledge Infrastructure database for randomized controlled trials (RCTs) on MTT in treating depression until October 19, 2023. …”
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8172
Comparison of GLP-1RAs vs Other Pharmacotherapy for Obesity
Published 2025-02-01“…We excluded articles older than 5 years or published in a language other than English. 19 meta-analyses and 2 randomized controlled trials (RCTs) were chosen, and 13 meta-analyses were excluded based on not meeting the inclusion criteria. 6 meta-analyses and 2 RCTs were included. …”
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8173
Land use changes, green house gas emissions, and rehabilitation model of native tree species towards sustainable management
Published 2024-10-01“…Cellular Automata-Markov is employed to forecast forthcoming land cover alterations by evaluating the likelihood of land cover transitions throughout a given period. Planting trials using native peatland tree species were conducted at 2 locations with 2 different rehabilitation models following social typology of the sites.FINDINGS: Key findings indicate that peatland conversion to non forest use significantly increases greenhouse gas emissions, while rehabilitation with native tree species shows promising results in carbon sequestration. …”
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Bioassays for the evaluation of the attractiveness of attractive targeted sugar bait (ATSB) against Anopheles mosquitoes in controlled semi-field systems
Published 2025-02-01“…Conclusions Data from these experiments support using ASBs v1.2.1, deployed in large-scale epidemiological trials, as it is the most attractive and shows the highest feeding success of the Westham prototypes tested. …”
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8176
Examining the therapeutic potential and side effects of calcium channel blockers in mortality and morbidity of patients with stroke: A systematic review of pre-clinical and clinica...
Published 2025-06-01“…Our inclusion criteria were randomized clinical trials, cohort studies, case-cross-over studies, case reports, and in-vitro and animal studies in which they evaluated the effects of calcium channel blockers on the CVA risk and mortality, morbidity, and long-term outcomes of stroke. …”
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8177
Does pregabalin offer potential as a first-line therapy for generalized anxiety disorder? A meta-analysis of efficacy, safety, and cost-effectiveness
Published 2025-02-01“…Efficacy and safety were evaluated using various scales and adverse events (AEs). Randomized clinical trials were included in the study. Four major databases were used for this study. …”
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Recommendations for the diagnosis and treatment of anti-neutrophil cytoplasmic autoantibody associated vasculitis
Published 2025-01-01“…The use of glucocorticoids, cyclophosphamide and other immunosupressants (such as azathioprine, mychophenolate and methotrexate) was optimised in a series of clinical trials that established the treatment of reference. …”
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Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti...
Published 2023-01-01“…Therefore, targeting epigenetic modifiers for cancer treatment has gained increasing interest, and inhibitors for various epigenetic modulators have been intensively studied in clinical trials. Here, we report a cross-entity, epigenetic drug screen to evaluate therapeutic vulnerabilities in MYC amplified MB, which sensitizes them to macrophage-mediated phagocytosis by targeting the CD47-signal regulatory protein α (SIRPα) innate checkpoint pathway.Methods We performed a primary screen including 78 epigenetic inhibitors and a secondary screen including 20 histone deacetylase inhibitors (HDACi) to compare response profiles in atypical teratoid/rhabdoid tumor (AT/RT, n=11), MB (n=14), and glioblastoma (n=14). …”
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Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder
Published 2024-04-01“…This further enables the identification of biomarkers and changes throughout development that will be essential for upcoming targeted trials of enzyme replacement and gene therapy.…”
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