Adolescent HIV prevent and care framework: A global scoping review protocol- BSGH 006. by Gamji Rabiu Abu-Ba'are, Osman Wumpini Shamrock, Darcey Rodriguez, George Rudolph Kofi Agbemedu, LaRon E Nelson

“…Additionally, a search will be conducted for grey literature using Global Index Medicus (WHO), MedNar (Deep Web Technologies), and Central Register of Controlled Trials (Cochrane). Duplicate removal and selection of articles that meet the inclusion criteria for the study will be performed using Covidence. …”
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Assessing the role of genotype by environment interaction as determinants of maize grain yield and lodging resistance by Haiwang Yue, Tiago Olivoto, Junzhou Bu, Jianwei Wei, Pengcheng Liu, Wei Wu, Maicon Nardino, Xuwen Jiang

“…Conclusion Overall, this study provides valuable insights into the effects of ETs on maize hybrids and enhances our understanding of GxE interactions in multi-environment trials. This understanding is essential for improving maize cultivation practices and breeding program in diverse environments.…”
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A human acellular dermal matrix coated with zinc oxide nanoparticles accelerates tendon repair in patients with hand flexor tendon injuries in zone 5 of the hand by Seyedeh-Sara Hashemi, Mohsen Pirmoradi, Alireza Rafati, Mehdi Kian, Ali Akbar Mohammadi, Mohamad Ali Hoghoughi

“…However, more comprehensive clinical trials are still needed.…”
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In vitro evaluation of the immunomodulatory and antibacterial activities of calcitriol (1,25-dihydroxy-vitamin D3) as a potential application for aerobic vaginitis treatment - prel... by Anna Tomusiak-Plebanek, Grażyna Więcek, Edyta Golińska, Magdalena Strus

“…However, conclusions regarding the potential use of calcitriol in the treatment of AV require further confirmation in in vivo studies as well as in well-designed clinical trials.…”
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Effectiveness of digital behaviour change interventions for promoting physical activity in adolescents with overweight and obesity: A systematic review and meta-analysis by Puteri Shanaz Jahn Kassim, Noor Azimah Muhammad, Nur Faraheen Abdul Rahman, Sherina Mohd Sidik, Cecilia A. Essau, Shamsul Azhar Shah

“…Methods Seven electronic databases were searched for randomized controlled trials and quasi-experimental studies evaluating DBCIs for physical activity promotion in adolescents with overweight and obesity aged 10–19 years. …”
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Achieving Medication‐Free Remission in Patients With Juvenile Dermatomyositis by Ilaria Maccora, Hermine I. Brunner, Amy Cassedy, Mekibib Altaye, Megan Quinlan‐Waters, Daniel J. Lovell, Alexei Grom, Sheila T. Angeles‐Han

“…MFR was defined as inactive JDM after discontinuation of all systemic immunosuppressives for ≥6 months, in line with international consensus guidelines for trials of therapies in idiopathic inflammatory myopathies. …”
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Cannabis related side effects in otolaryngology: a scoping review by Jobanjit S. Phulka, Joel W. Howlett, Amanda Hu

“…Oxford Centre for Evidence-Based Medicine: Levels of Evidence and risk of bias using the Risk of Bias in randomized trials (RoB 2) and Risk of Bias in Non-Randomized Studies of Interventions (ROBINS-I) tools were assessed.. …”
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Negative symptoms in schizophrenia: a study in a large clinical sample of patients using a novel automated method by Robert Stewart, Hitesh Shetty, Matthew Broadbent, Angus Roberts, Rashmi Patel, Philip McGuire, Richard D Hayes, Nishamali Jayatilleke, Genevieve Gorrell, Chin-Kuo Chang, Richard Jackson, Nadia Foskett, Caroline Johnston

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A maChine and deep Learning Approach to predict pulmoNary hyperteNsIon in newbornS with congenital diaphragmatic Hernia (CLANNISH): Protocol for a retrospective study. by Ilaria Amodeo, Giorgio De Nunzio, Genny Raffaeli, Irene Borzani, Alice Griggio, Luana Conte, Francesco Macchini, Valentina Condò, Nicola Persico, Isabella Fabietti, Stefano Ghirardello, Maria Pierro, Benedetta Tafuri, Giuseppe Como, Donato Cascio, Mariarosa Colnaghi, Fabio Mosca, Giacomo Cavallaro

“…<h4>Registration</h4>The study was registered at ClinicalTrials.gov with the identifier NCT04609163.…”
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Outcomes of total hip replacement in adults with septic arthritis of the native hip joint: A systematic review by Teddy Cheong, Surya Varma Selvakumar, Ryan Kwang Jin Goh, Ing How Moo

“…However, more prospective and randomized trials are needed to establish clear protocols on antibiotic regimes, clinical criteria clearance, and optimal time from infection to joint replacement.…”
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African animal trypanocide resistance: A systematic review and meta-analysis by Keneth Iceland, Kasozi, Ewan, Thomas MacLeod, Susan, Christina Welburn

“…Methods: A total of seven electronic databases were screened for an article on trypanocide resistance in AATr by using keywords on preclinical and clinical trials with the number of animals with treatment relapse, days taken to relapse, and resistant gene markers using the PRISMA checklist. …”
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Role of Cannabis in the Management of Chronic Non-Cancer Pain: A Narrative Review by Lou’i Al-Husinat, Shrouq Obeidat, Saif Azzam, Yara Al-Gwairy, Fatima Obeidat, Sarah Al Sharie, Deema Haddad, Fadi Haddad, Martina Rekatsina, Matteo Luigi Giuseppe Leoni, Giustino Varrassi

“…Future research should prioritize long-term clinical trials to establish optimal dosing, efficacy, and safety, aiding in the development of informed guidelines for safe cannabis use in chronic pain management. …”
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Microbial consortium culture and vermi-composting technologies for recycling on-farm wastes and food production by Girish Chander, Suhas P. Wani, S. Gopalakrishnan, Ankita Mahapatra, Swati Chaudhury, C. S. Pawar, Manoj Kaushal, A. V. R. Kesava Rao

“…Compost quality was tested for macro-, micro-nutrients and C:N ratio, and evaluated for food production in on-farm trials. Results 16S rDNA analysis screened sixteen bacterial isolates—eight related to genus Bacillus, three to each Halobacillus and Staphylococcus, one to each Microbacterium and Streptomyces. …”
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HPK1 kinase inhibitor: a sufficient approach to target HPK1 to modulate T cell activation in cancer immunotherapy compared with degraders by Qin Wang, Xinyi Zhu, Jing Li, Sanjia Xu, Ali Wang, Xinwen Zhang, Xingxing Wang, Xiaopeng Cai, Haimei Xing, Ye Liu, Xuesong Liu, Zhiwei Wang, Lai Wang, Lai Wang, Xi Yuan

“…Several compounds have been developed and tested in clinical trials to target HPK1 for cancer immunotherapy. However, whether kinase inhibition is sufficient to eliminate the immunosuppressive function of HPK1, particularly in T cells, remains elusive.MethodsIn this study, genetic tools were used to edit the human T lymphocyte cell line Jurkat. …”
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Evidence-based exercise recommendations to improve functional mobility in older adults - A study protocol for living systematic review and meta-analysis [version 2; peer review: 2... by Claudia Volecker-Rehage, Uros Marusic, Bettina Wollesen, Antoine Langeard, Tamar Yellon, Anna Wunderlich, Vera Belkin, Guoping Qian, Eleftheria Giannouli, Zbigniew Ossowski, Rafael A. Bernades, Yael Netz, Rajesh Sighdel

“…Inclusion criteria are: healthy older people ≥ 50 years, randomized-controlled trials including exercise intervention and a walking or mobility assessments (eg., TUG, SPPB) as an outcome measure. …”
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Inverse relationship of oxidative balance score with hyperuricemia among Chinese adults: a population-based cross-sectional study by Hewei Peng, Ying Han, Jingru Huang, Wenxin Qiu, Huajing Chang, Jiangwang Fang, Xian-E Peng

“…Large prospective cohort studies and randomized controlled trials are required to verify the effect of OBS on hyperuricemia and elucidate its causal mechanism.…”
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The Genetic Landscape of Human Glioblastoma and Matched Primary Cancer Stem Cells Reveals Intratumour Similarity and Intertumour Heterogeneity by Chiara Pesenti, Stefania Elena Navone, Laura Guarnaccia, Andrea Terrasi, Jole Costanza, Rosamaria Silipigni, Silvana Guarneri, Nicola Fusco, Laura Fontana, Marco Locatelli, Paolo Rampini, Rolando Campanella, Silvia Tabano, Monica Miozzo, Giovanni Marfia

“…Despite countless experimental researches for new therapeutic strategies and promising clinical trials, the prognosis remains extremely poor, with a mean survival of less than 14 months. …”
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Advances in Cell and Immune Therapies for Melanoma by Tanase Timis, Sanda Buruiana, Delia Dima, Madalina Nistor, Ximena Maria Muresan, Diana Cenariu, Adrian-Bogdan Tigu, Ciprian Tomuleasa

“…However, the limitations of the PD-1/PD-L1 and CTLA-4 axes inhibitors, such as low response rates, treatment resistance, and toxicity, have driven the need for continued research and advancements in treatment strategies. Current clinical trials are exploring various combinations of immune checkpoint inhibitors with costimulatory receptor agonists, chemotherapy, targeted therapies, and other immunotherapies, with the goal of improving outcomes and reducing side effects for melanoma patients. …”
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The safety and effectiveness of tDCS for epileptic patients: A systematic review and meta-analysis by Xiao-Tong Ding, Ming-Yu Hu, Chi Wang, Wei-Ye Kang, Jin-Zhao Huang, Rui-Yu Wang, Qiu-Song Shen, Hou-Ming Kan

“…The meta-analysis was conducted using Review Manager 5.4 software. Results: 12 trials were included, 356 participants (219 in the tDCS group and 137 in the sham group). …”
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Evidence in Lager Yeasts of β-Lyase Activity Breaking Down γ-GluCys-Conjugates More Efficiently Than Cys-Conjugates to Odorant Beer Polyfunctional Thiols by Romain Christiaens, Margaux Simon, Raphaël Robiette, Sonia Collin

“…The prevalence of glutathionylated (G-) precursors of polyfunctional thiols (PFTs) over their free forms has prompted investigating how to optimize the enzymatic breakdown of these precursors with yeast during lager, ale, and non-alcoholic/low-alcoholic beer (NABLAB) fermentation trials. Some <i>Saccharomyces cerevisiae</i> yeasts have been selected for their higher β-lyase activity on the cysteinylated (Cys-) conjugates (up to 0.54% for SafAle^TM K-97), yet some <i>S. pastorianus</i> strains and one maltose-negative <i>S. cerevisiae</i> var. …”
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