Hypertension and retinal microvascular dysfunction (HyperVasc): protocol of a randomised controlled exercise trial in patients with hypertension by Justin Carrard, Lukas Streese, Timo Hinrichs, Henner Hanssen, Arno Schmidt-Trucksäss, Konstantin Gugleta, Joséphine Gander, Christoph Hauser

“…All participants will give informed consent.Trial registration number NCT04763005.…”
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Preimplantation genetic testing for aneuploidy in severe male factor infertility: protocol for a multicenter randomised controlled trial by Li Wang, Li Jin, Yao Lu, Chen Zhang, He-Feng Huang, Yun Sun, Xian-hua Lin, Meng-xi Guo, Dan-dan Wu, Jian-lin Zhang, Cheng-liang Zhou, Chen-ming Xu, Song-chang Chen, Song-ying Zhang, Xiao-xi Sun, Yan-ting Wu

“…The findings will be disseminated to the public through conference presentations and publication in peer-reviewed scientific journals.Trial registration number ClinicalTrials.gov, NCT02941965.…”
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Hypotension prediction index for minimising intraoperative hypotension: A systematic review and meta-analysis of randomised controlled trials by Kamath Sriganesh, Thomas Francis, Rajeeb Kumar Mishra, Nisarga N Prasad, Dhritiman Chakrabarti

“…Therefore, the aim of this systematic review and meta-analysis of randomised controlled trials (RCTs) was to evaluate the overall effect of using HPI on intraoperative hypotension outcomes of time-weighted average (TWA), area under the hypotension threshold (AUHT), incidence and duration of hypotension. …”
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Echocardiographic phenotypes of diabetic myocardial disorder: evolution over 15 months follow-up in the ARISE-HF trial by Thomas H. Marwick, Carolyn Lam, Yuxi Liu, Stefano Del Prato, Julio Rosenstock, Javed Butler, Justin Ezekowitz, Nasrien E. Ibrahim, W. H. Wilson Tang, Faiez Zannad, Riccardo Perfetti, James L. Januzzi

“…Methods The Aldose Reductase Inhibition for Stabilization of Exercise Capacity in Heart Failure (ARISE-HF) trial was a Phase 3 randomised trial of an aldose reductase inhibitor in patients with well-controlled type 2 diabetes mellitus (T2DM). …”
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First Trials of Genome Analyses in Some Onobrychis Species using Dot-Blot and Genomic in situ Hybridization Techniques by Metin Tuna, Evren Cabi, Bozena Kolano, Gülru Yücel

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Comparing the effects of Mycozin and Clotrimazole 1% creams on vaginal candidiasis: a triple-blinded randomized controlled trial by Khadije Hajizadeh, Zahra Alivand, Vahideh Rahmani, Leila Mehrannia, Sanam Nami, Behrooz Shokouhi, Mojgan Mirghafourvand

“…Date of registration: 20/05/2023; URL: https://irct.behdasht.gov.ir/user/trial/68718/view ; Date of first registration: 31/05/2023.…”
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Alendronate versus Raloxifene for Postmenopausal Women: A Meta-Analysis of Seven Head-to-Head Randomized Controlled Trials by Tiao Lin, Shi-Gui Yan, Xun-Zi Cai, Zhi-Min Ying, Fu-Zhen Yuan, Xi Zuo

“…Seven randomized controlled trials (RCTs) involving 4054 women were identified and included. …”
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Balance rehabilitation with a virtual reality protocol for patients with hereditary spastic paraplegia: Protocol for a clinical trial. by Bianca Simone Zeigelboim, Maria Renata José, Geslaine Janaina Bueno Dos Santos, Maria Izabel Rodrigues Severiano, Hélio Afonso Ghizoni Teive, José Stechman-Neto, Rosane Sampaio Santos, Cristiano Miranda de Araújo, Bianca Lopes Cavalcante-Leão

“…<h4>Methods</h4>In this randomized controlled clinical trial from the Rebec platform RBR-3jmx67 in which allocation concealment was performed and the evaluators be blinded will be included. …”
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Whole-Body Electromyostimulation to Fight Osteopenia in Elderly Females: The Randomized Controlled Training and Electrostimulation Trial (TEST-III) by Simon von Stengel, Michael Bebenek, Klaus Engelke, Wolfgang Kemmler

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The efficacy and safety of Vonoprazan and Tegoprazan in eradication: a comprehensive systematic review and meta-analysis of randomized controlled trials by Ting Jin, Wei Wu, Lei Zhang, Han Xuan, Haixiang Zhang, Li Zhong

“…Results: The analysis totally included 28 randomized controlled trials (RCTs) comprising 37 studies and 8818 patients diagnosed with H. pylori infection. …”
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Characterization of Two Historical Postage Stamps Made from Cotton Fibers and Their Restoration Trials Based on the Experimental Studies by Maisa M.A. Mansour, Yassin E. Zidan, Abou El Fettouh A Abd El Hakim, Mohamed Mahmoud Allam, Hayssam M. Ali, Mohammad Akrami, Mohamed Z. M. Salem

“…The two historical stamps were documented through different spectroscopic analyses, and from the restoration trials, it was observed that the mixture of 7% Klucel G + 0.2% TiO2 NP appeared to be a new and effective method for recovering the historical postage stamps.…”
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Efficacy and safety of Xiongzhitongluo granules in the treatment of acute ischemic stroke: study protocol for a randomized controlled trial by Yunmeng Chen, Jingjing Wei, Xiao Liang, Yue Liu, Lina Miao, Di Zhao, Yunfan Zhang, Hongxi Liu, Yunling Zhang

“…Our team developed Xiongzhitongluo granules specifically for AIS and is conducting a randomized controlled trial (RCT) to validate their effectiveness.Methods and analysisThis multi-center, randomized, double-blind, placebo-controlled clinical trial includes 120 participants randomly allocated to the intervention or placebo group. …”
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Palmitoylethanolamide supplementation for human health: A state-of-the-art systematic review of Randomized Controlled Trials in patient populations by R. Bortoletto, C. Comacchio, M. Garzitto, F. Piscitelli, M. Balestrieri, M. Colizzi

“…This Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020-compliant systematic review aimed at collecting and comprehensively discussing all available data from Randomized Controlled Trials (RCTs) evaluating the efficacy and tolerability of PEA supplementation across human illnesses in patient populations. …”
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A Randomised Controlled Trial of Efficacy of Cognitive Rehabilitation in Multiple Sclerosis: A Cognitive, Behavioural, and MRI Study by J. Campbell, D. Langdon, M. Cercignani, W. Rashid

“…This study supports the hypothesis that home-based, computerised, cognitive rehabilitation may be effective in improving cognitive performance in patients with MS. Clinical trials registration is ISRCTN54901925.…”
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Randomized Clinical Trial Comparing The Effect Of Oral Rehydration Therapy With And Without Racecadotril In The Management Of Acute Diarrhea In Children by Sughra Zulfiqar, Hifza Zeb, Nadia Mumtaz, Ammara Musthaq Khan, Taimur Khalil Sheikh, Tariq Saeed

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Clinical Effectiveness, Access to, and Satisfaction with Care Using a Telehomecare Substitution Intervention: A Randomized Controlled Trial by Kathryn H. Bowles, Alexandra L. Hanlon, Henry A. Glick, Mary D. Naylor, Melissa O'Connor, Barbara Riegel, Nai-Wei Shih, Mark G. Weiner

“…Randomized controlled trial to compare a telehomecare intervention for patients 55 and older following hospital discharge for HF to usual skilled home care. …”
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Transcutaneous vagus nerve stimulation as a pain modulator in knee osteoarthritis: a randomized controlled clinical trial by Gehad Gamal Elsehrawy, Maha Emad Ibrahim, Nermeen Hassan A.moneim, Mohamed Ahmed Hefny, Nashwa Kamel El Shaarawy

“…Conclusion There is preliminary evidence to support the benefits of tVNS in OA, suggesting that neuromodulation can be used as an adjunct to existing pharmacological and non-pharmacological treatments. Trial registration The study was registered on ClinicalTrials.gov (NCT05387135) on 24/05/2022.…”
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Self‐Efficacy in Hypertension Management Using e‐Health Technology: A Randomized Controlled Trial in Primary Care by Rasmus Hermansson‐Borrebaeck, Andreas Fors, Ulrika Bengtsson, Karin Kjellgren, Susanna Calling, Patrik Midlöv

“…This multicenter randomized controlled trial included 949 primary healthcare patients with hypertension. …”
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Evaluating the effectiveness of a mental health literacy module - A randomized controlled trial among school teachers by Vidya Prabhu, Lena Ashok, Veena Ganesh Kamath, Amitha Puranik, Sebastian Padickaparambil, Nikitha Sibil Rebello, Praveen Arhanthabailu, Varalakshmi Chandrasekaran

“…Methods: A parallel stratified cluster randomized controlled trial was conducted among high school teachers between November 2019 to September 2021. …”
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Effect of Transcranial Direct Current Stimulation (TDCS) on Depression in Older Adults: A Pilot Randomized Controlled Trial by M. Zareie, S. Balal Habashi, P. Farokhnezhad Afshar

“…This study is an unblinded randomized controlled trial. We selected 60 patients with depression based on the Geriatric Depression Scale (GDS) and randomly divided them into two groups. …”
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