Pilot Trial on Ischemic Conditioning of the Gastric Conduit in Esophageal Cancer: Feasibility and Impact on Anastomotic Leakage (TIGOAL-I) by María-Carmen Fernández-Moreno, MD, PhD, María Eugenia Barrios Carvajal, MD, Fernando López Mozos, MD, PhD, Roberto Martí Obiol, MD, PhD, Jorge Guijarro Rozalén, MD, PhD, Elisabetta Casula, MD, PhD, Joaquín Ortega, MD, PhD

“…This pilot randomized clinical trial was conducted between April 2016 and October 2021 at a single-center tertiary hospital. …”
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Concentric and Eccentric Force Changes with Elastic Band and Isotonic Heavy Resistance Training: A Randomized Controlled Trial by Eric Folkins, Sidharth Sahni, John Ryan, Stacey Wooden, Gina Bushby, Christian Radzinski

“… # Study Design Randomized Trial # Methods Twenty healthy females performed pre-and-post isokinetic (60 degrees/second) concentric/eccentric testing of the elbow flexors, shoulder external rotators, and hip abductors. …”
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Efficacy and safety of massage for postoperative stress in colorectal cancer patients: a randomized, controlled, three-arm trial by Paul G. Werthmann, Paul G. Werthmann, Paul G. Werthmann, Dirk Cysarz, Melanie Jungbluth, Ann-Kathrin Lederer, Ann-Kathrin Lederer, Gergana Nenova, Roman Huber, Monique van Dijk, Gunver S. Kienle

“…Furthermore, the patient’s preferences and previous experiences with massage therapy should be considered.Clinical trial registrationGerman Clinical Trials Register (www.drks.de), identifier DRKS00023407.…”
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Photobiomodulation preconditioning for oral mucositis prevention and quality of life improvement in chemotherapy patients: a randomized clinical trial by Marwa Khalil, Omar Hamadah, Maher Saifo

“…Materials and methods This is a prospective, randomized, double-blind clinical trial including 45 patients divided into three age- and sex-matched groups. …”
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Internet-based cognitive behavioural therapy for adults with tinnitus in the UK: study protocol for a randomised controlled trial by Peter M Allen, David M Baguley, Gerhard Andersson, Eldré W Beukes, Vinaya Manchaiah

“…This would be cost effective and potentially will free up services for those with more severe problems that need face-to-face treatment.Trial registration number ClinicalTrials.gov; NCT02370810, date 05/03/2015.…”
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The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: A randomized trial by Gansheng Tan, Anna L Huguenard, Kara M Donovan, Phillip Demarest, Xiaoxuan Liu, Ziwei Li, Markus Adamek, Kory Lavine, Ananthv K Vellimana, Terrance T Kummer, Joshua W Osbun, Gregory J Zipfel, Peter Brunner, Eric C Leuthardt

“…Methods: In this randomized clinical trial, 24 SAH patients were assigned to either a taVNS treatment or a sham treatment group. …”
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Incompatible Aedes aegypti male releases as an intervention to reduce mosquito population-A field trial in Puerto Rico. by Liliana Sánchez-González, Jacob E Crawford, Laura E Adams, Grayson Brown, Kyle R Ryff, Mark Delorey, Jose Ruiz-Valcarcel, Nicole Nazario, Nexilianne Borrero, Julieanne Miranda, Sara N Mitchell, Paul I Howell, Johanna R Ohm, Charlie Behling, Brian Wasson, Craig Eldershaw, Bradley J White, Vanessa Rivera-Amill, Roberto Barrera, Gabriela Paz-Bailey

“…New mosquito control technologies are needed to complement existing methods, given current challenges with scalability, acceptability, and effectiveness. A field trial was conducted in collaboration with the Communities Organized to Prevent Arboviruses project in Ponce, Puerto Rico, to measure entomological and epidemiological effects of reducing Aedes aegypti populations using Wolbachia incompatible insect technique. …”
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A Randomized Controlled Trial Comparing Sequential with Triple Therapy for Helicobacter pylori in an Aboriginal Community in the Canadian North by Amy L Morse, Karen J Goodman, Rachel Munday, Hsiu-Ju Chang, John Morse, Monika Keelan, Janis Geary, Sander Veldhuyzen van Zanten, CAN Help Working Group

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Bearberry in the treatment of acute uncomplicated cystitis (BRUMI): protocol of a multicentre, randomised double-blind clinical trial by Péter Hegyi, Noémi Gede, Szilárd Váncsa, Barbara Tóth, András Jávorházy, Péter Nyirády, Boglárka Csupor-Löffler, Péter Birinyi, George Zhanel, Kurt Naber, Reinhard Länger, Nóra Vörhendi, Dezső Csupor

“…The results will be disseminated by publication of peer-reviewed manuscripts.Trial registration number NCT05055544.…”
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Effect of photobiomodulation as preventive treatment of diabetic foot ulcer: randomised, controlled, double-blind, clinical trial protocol by Lara Jansiski Motta, Anna Carolina Ratto Tempestini Horliana, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari, Sandra Kalil Bussadori, Roselene Lourenço, Silvana Torres Perez, Cinthya Cosme Gutierrez Duran, Alexandre Rocha Santos Padilha, Tainá Caroline dos Santos Malavazzi

“…The findings will be published in a peer-reviewed journal.Trial registration number NCT06353568, ClinicalTrials.gov.…”
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Mindfulness influences the psycho-social dimension of chronic pain: A randomized controlled clinical trial in Indian context by Anirban Pal, Purnava Mukhopadhyay, Rajasree Biswas, Dipasri Bhattacharya

“…The aim of this randomized controlled trial was to see the effects of mindfulness on pain intensity, pain catastrophizing, chronic pain acceptance, perceived stress, well-being, and mindfulness characteristics. …”
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Analgesic Effects of Preincision Ketamine on Postspinal Caesarean Delivery in Uganda’s Tertiary Hospital: A Randomized Clinical Trial by Richard Mwase, Tonny Stone Luggya, John Mark Kasumba, Humphrey Wanzira, Andrew Kintu, Joesph V. B. Tindimwebwa, Daniel Obua

“…We recommend larger studies to explore this benefit. This trial is registered with Pan African Clinical Trial Registry number PACTR201404000807178.…”
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Randomized Clinical Trial of a Self-Adhering Flowable Composite for Class I Restorations: 2-Year Results by J. Sabbagh, S. Dagher, N. El Osta, P. Souhaid

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Multicentre, randomised controlled trial to investigate the effects of parental touch on relieving acute procedural pain in neonates (Petal) by Eleri Adams, Daniel Crankshaw, Ria Evans Fry, Rebeccah Slater, Caroline Hartley, Maria M Cobo, Fiona Moultrie, Annalisa G V Hauck, Vaneesha Monk, Shellie Robinson, Marianne van der Vaart, Luke Baxter, Ravi Poorun, Aomesh Bhatt

“…Stroking of the skin can activate C-tactile fibres and reduce pain, and therefore could provide a simple and safe parent-led intervention for the management of pain. The trial aim is to determine whether parental touch prior to a painful clinical procedure provides effective pain relief in neonates.Methods and analysis This is a multicentre randomised controlled trial. …”
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Motivational interviewing to improve self‐care in heart failure patients (MOTIVATE‐HF): a randomized controlled trial by Ercole Vellone, Paola Rebora, Davide Ausili, Valentina Zeffiro, Gianluca Pucciarelli, Gabriele Caggianelli, Stefano Masci, Rosaria Alvaro, Barbara Riegel

“…Including caregivers may potentiate the effect, especially in self‐care management. ClinicalTrial.gov, identifier: NCT02894502.…”
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Internet-based cognitive–behavioural therapy for insomnia (ICBT-i): a meta-analysis of randomised controlled trials by Jia Chen, Juan Liu, Yuan-yuan Ye, Ni-ka Chen, Ling Lin, Ya-zhen Liu, Ying Lang, Xun-jun Li, Xin-ju Yang, Xiao-jiang Jiang

“…Objective To evaluate the effectiveness of internet-based cognitive–behavioural therapy for insomnia (ICBT-i) in adults.Design A meta-analysis of ICBT-i.Data sources Systematic searches of randomised controlled trials of ICBT-i were performed in the PubMed, EMBASE, PsycINFO and Cochrane Library databases up to 19 June 2016.Review method 2 reviewers independently performed study selection, quality assessment and data extraction. …”
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Rifaximin treatment in patients with severe alcoholic hepatitis: A multicenter, randomized controlled, open-label, pilot trial by Do Seon Song, Jin Mo Yang, Young Kul Jung, Hyung Joon Yim, Hee Yeon Kim, Chang Wook Kim, Soon Sun Kim, Jae Youn Cheong, Hae Lim Lee, Sung Won Lee, Jeong-Ju Yoo, Sang Gyune Kim, Young Seok Kim

“…The MELD score was the only significant factor for short-term mortality. Clinical trial registration: The study was registered on ClinicalTrials.gov (number: NCT02485106).…”
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Improvement of Fatigue in Patients with Ankylosing Spondylitis Receiving Tofacitinib: Analyses of a Phase 3 Randomized Controlled Trial by Laure Gossec, Jessica A. Walsh, Raj Sengupta, Andrew G. Bushmakin, Joseph C. Cappelleri, Arne Yndestad, Oluwaseyi Dina, David Cella

“…These results may be useful for healthcare providers when discussing tofacitinib treatment expectations with patients. Trial Registration ClinicalTrials.gov: NCT03502616 (June 7, 2018).…”
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Randomized clinical trial of a digital integrative medicine intervention among patients undergoing active cancer treatment by Jun J. Mao, Karolina Bryl, Erin F. Gillespie, Angela Green, Tony K. W. Hung, Raymond Baser, Katherine Panageas, Michael A. Postow, Bobby Daly

“…These promising findings should be confirmed in phase III clinical trials. “Study registered at clinicaltrials.gov (NCT05053230) on 09-20-2021”.…”
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Effectiveness of Anti-Gravity Treadmill Exercise After Total Knee Arthroplasty: Protocol for a Randomized Controlled Trial by Elina Jääskeläinen, Mikko Manninen, Heikki Hurri, Mikko Rantasalo, Yun Zhou, Hannu Kautiainen, Leena Ristolainen

“…MethodsThis randomized controlled trial study divided the patients into two groups: the intervention group and the control group. …”
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