Adaptive Just-in-Time Intervention to Reduce Everyday Stress Responses: Protocol for a Randomized Controlled Trial by Jillian A Johnson, Matthew J Zawadzki, Martin J Sliwinski, David M Almeida, Orfeu M Buxton, David E Conroy, David Marcusson-Clavertz, Jinhyuk Kim, Robert S Stawski, Stacey B Scott, Christopher N Sciamanna, Paige A Green, Emily M Repka, Meynard John L Toledo, Nicole L Sturges, Joshua M Smyth

“…MethodsIn a 2-arm phase 2 clinical trial, we will enroll 210 adults in either a JIT stress management intervention or an active control condition. …”
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Assessing the Inter-Rater and Inter-Trial Reliability of the NeurOptics Pupillary Light Response-3000 Pupillometer by Deborah A Jehu, Lori A Bolgla, Samantha Armas, Forest Dutton

“…Data for the average and individual trials of each PLR parameter were used to determine inter-rater and inter-trial reliability, respectively. …”
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The Effect of Low Carbohydrate Diet on Polycystic Ovary Syndrome: A Meta-Analysis of Randomized Controlled Trials by Xiaoshuai Zhang, Yang Zheng, Yanan Guo, Zhiwen Lai

“…Data from randomized controlled trials (RCTs) were obtained to perform a meta-analysis of the effects of LCD in PCOS patients. …”
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Evaluation of in-office tooth whitening treatment with violet LED: protocol for a randomised controlled clinical trial by Lara Jansiski Motta, Anna Carolina Ratto Tempestini Horliana, Sandra Kalil Bussadori, Maria Fernanda Setúbal Destro Rodrigues, Ana Eliza Castanho Garrini dos Santos, Marcelo Mendes Pinto, Dácio Antonio Pantano Junior, Aldo Brugnera Jr, Fátima Antonia Aparecida Zanin

“…The findings will be published in a peer-reviewed journal.Trial registration number NCT03192852; Pre-results.…”
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The Effects of Physical Activity Feedback on Behavior and Awareness in Employees: Study Protocol for a Randomized Controlled Trial by Karen Van Hoye, Filip Boen, Johan Lefevre

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Game theory and weight loss: Harmonic evidence from randomized controlled trials in Appalachia, KY and Jordan. by Daniel E Zoughbie, Dillon Huddleston, Eric L Ding

“…For the first time, we are showing increased cooperative behaviors causally associated with these trials.…”
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Designing an exploratory phase 2b platform trial in NASH with correlated, co-primary binary endpoints. by Elias Laurin Meyer, Peter Mesenbrink, Nicholas A Di Prospero, Juan M Pericàs, Ekkehard Glimm, Vlad Ratziu, Elena Sena, Franz König, EU-PEARL NASH Investigators

“…Non-alcoholic steatohepatitis (NASH) is the progressive form of nonalcoholic fatty liver disease (NAFLD) and a disease with high unmet medical need. Platform trials provide great benefits for sponsors and trial participants in terms of accelerating drug development programs. …”
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A Randomized Trial of Ionic Silver Dressing to Reduce Surgical Site Infection After Gastrointestinal Surgery by Chihiro Kosugi, MD, Keiji Koda, MD, Hiroaki Shimizu, MD, Masato Yamazaki, MD, Kiyohiko Shuto, MD, Mikito Mori, MD, Akihiro Usui, MD, Hiroyuki Nojima, MD, Satoshi Endo, MD, Hiroo Yanagibashi, MD, Hidehito Arimitsu, MD, Toru Tochigi, MD, Tetsutaro Sazuka, MD, Mihono Hirota, MD, Hideyuki Kuboki, MD

“…Background:. Multiple clinical trials have assessed the effectiveness of silver-containing wound dressings; however, systematic reviews failed to find any advantages of these dressings and concluded that there was insufficient evidence to indicate that they prevented wound infections. …”
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Screening for Atrial Fibrillation by Digital Health Technology in Older People in Homecare Settings: A Feasibility Trial by Edvard Liljedahl Sandberg, Sigrun Halvorsen, Trygve Berge, Jostein Grimsmo, Dan Atar, Bjørnar Leangen Grenne, Jarle Jortveit

“…Users of homecare services are often excluded from clinical trials due to advanced age, multimorbidity, and frailty. …”
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Evaluating the Effectiveness of InsightApp for Anxiety, Valued Action, and Psychological Resilience: Longitudinal Randomized Controlled Trial by Victoria Amo, Falk Lieder

“…ObjectiveThis randomized controlled trial aims to examine the effectiveness of InsightApp in (1) improving individuals’ metacognitive strategies for coping with stress and anxiety and (2) promoting value-congruent action. …”
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Impact of Online Stress Management Training Program on the Sexual Function of Perimenopausal Women: A Clinical Trial by Leila Neisani Samani, Shima Arjmand, Naeimeh Seyedfatemi, Shima Haghani

“…Materials & Methods This is a clinical trial with a pre-test/post-test design that was conducted on 50 perimenopausal women aged 40-50 referring to Sohrab Ali Bakhshi comprehensive health center in Shahriar town, Tehran, Iran, in 2022, who were selected using a continuous sampling method. …”
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Evaluation of efficacy and safety of coenzyme Q10 in pediatric hemodialysis patients: a randomized controlled trial by Salma A. Rahman Sharaf, Sarah Farid Fahmy, Heba M. Adel Abou Zaghla, Ahmed Hussein Hassan, Sara Mahmoud Zaki

“…Abstract Background There is evidence from clinical trials that coenzyme Q10 significantly improves mitochondrial function and decreases oxidative stress and cardiovascular disease in adult hemodialysis patients. …”
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Costoclavicular block as a diaphragm-sparing nerve block for shoulder surgery: a randomized controlled trial by Youngin Lee, Seunguk Bang, Jihyun Chung, Min Suk Chae, Jungwon Shin

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Patient-centered outcomes for clinical trials in chronic rhinosinusitis with or without nasal polyps and allergic fungal rhinosinusitis by Brittany Klooster, Kaitlin Chatterton, Nazifa Ibrahim, Madison C. Bernstein, Alan L. Shields, Veleka Allen

“…Methods Literature, clinical trial, and product label reviews were conducted to identify symptoms, impacts, and COAs used to assess CRSwNP, CRSsNP, and AFRS patient experiences in clinical trials. …”
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Efficacy and Adverse Effects of Atropine for Myopia Control in Children: A Meta-Analysis of Randomised Controlled Trials by ChunWen Chen, JingYan Yao

“…We selected randomised controlled trials (RCTs) that evaluated the efficacy of atropine for controlling myopia progression in children. …”
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Multicenter Randomized Clinical Trial of Brief Psychotherapy versus Usual Treatment for Common Mental Disorders in Adults by Marco A. Luengo-Castro, Javier Fernández-Méndez, José M. García-Montes, Pedro J. Caunedo-Riesco, Juan M. García-Haro, Begoña Braña-Menéndez, Dolores González-Díaz, Andrés Cabero-Álvarez, Marcelino Cuesta-Izquierdo

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CLINTERVENTIONAL protocol: a randomized controlled trial to evaluate clinical consultations and audiovisual tools for interventional radiology by Pedro Blas García Jurado, Juan José Espejo Herrero, María Sagrario Lombardo Galera, María Eugenia Pérez Montilla, Sara Barranco Acosta, José García-Revillo, Pilar Font Ugalde, Marina Álvarez Benito

“…The single-center randomized controlled trial will include 428 patients undergoing IR procedures. …”
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Kidney REPLACEment therapies in patients with acute kidney injury and RHABDOmyolysis (ReplaceRhabdo): a pilot trial by Lorenz Weidhase, Antonia Borrmann, Anja Willenberg, Meinhard Mende, Christina Scharf-Janßen, Sirak Petros, Jonathan de Fallois

“…The time-dependent elimination performance could be further increased by combining KRT with more frequent adsorber exchange. Trial registration German Clinical Trials Registry ( DRKS00023998 ); date of registration 03/03/2021.…”
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From Lab to Clinic: Effect of Academia–Industry Collaboration Characteristics on Oncology Phase 1 Trial Entry by Wonseok Yang, Sang‐Won Lee

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Evaluation of two electronic-rehabilitation programmes for persistent knee pain: protocol for a randomised feasibility trial by Philip G Conaghan, Kim L Bennell, Mark Conner, Rana S Hinman, Sarah R Kingsbury, Elizabeth M A Hensor, Gretl A McHugh, Christine Comer, Dawn Groves-Williams, Rachel K Nelligan

“…Digital technologies may help address this, and this trial will evaluate the feasibility and acceptability of two electronic-rehabilitation interventions: ‘My Knee UK’ and ‘Group E-Rehab’.Methods and analysis This protocol describes a non-blinded, randomised feasibility trial with three parallel groups. …”
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