Response to Statin Therapy in Obstructive Sleep Apnea Syndrome: A Multicenter Randomized Controlled Trial by Marie Joyeux-Faure, Renaud Tamisier, Jean-Philippe Baguet, Sonia Dias-Domingos, Stephen Perrig, Georges Leftheriotis, Jean-Paul Janssens, Wojciech Trzepizur, Sandrine H. Launois, Françoise Stanke-Labesque, Patrick A. Lévy, Frédéric Gagnadoux, Jean-Louis Pepin

“…In OSA patients, 3 months of atorvastatin neither improved endothelial function nor reduced early signs of atherosclerosis although it lowered blood pressure and improved lipid profile. This trial is registered with NCT00669695.…”
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Extracorporeal Hemadsorption versus Glucocorticoids during Cardiopulmonary Bypass: A Prospective, Randomized, Controlled Trial by Gordana Taleska Stupica, Maja Sostaric, Marija Bozhinovska, Lea Rupert, Zoran Bosnic, Ales Jerin, Alojz Ihan, Tomislav Klokocovnik, Matej Podbregar

“…Hemadsorption with CytoSorb® was safe and well tolerated. This trial is registered with clinicaltrials.gov (NCT02666703).…”
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Three-Year Follow-Up of Participants from a Self-Weighing Randomized Controlled Trial by Lua Wilkinson, Carly R. Pacanowski, David Levitsky

“…Three years after this trial's end, participants were contacted for an update on their weight and self-weighing frequency. …”
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Efficacy of contralateral acupuncture in women with migraine without aura: protocol for a randomised controlled trial by Ling Zhao, Qifu Li, Yanan Wang, Jialei Feng, Xinghe Zhang, Siwen Zhao, Chonghui Xing, Yongli Song, Xuanxiang Zeng, Meng Kong, Yunqiu Zheng, Taipin Guo

“…The results of this study will be published in a peer-reviewed journal and presented at conferences.Trial registration number Chinese Clinical Trial Registration Center (ChiCTR2100051479).…”
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The Effects of Lutein and Zeaxanthin Supplementation on Brain Morphology in Older Adults: A Randomized, Controlled Trial by Catherine M. Mewborn, Cutter A. Lindbergh, B. Randy Hammond, Lisa M. Renzi-Hammond, L. Stephen Miller

“…While results suggest that one year of L and Z supplementation may have limited effects on structural brain outcomes overall, there may be a subsample of individuals for whom supplementation of L and Z provides greater benefits. ClinicalTrials.gov number, NCT02023645.…”
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Safety and immunogenicity of Ad26.COV2.S in adolescents: Phase 2 randomized clinical trial by Jelena Tica, Veronica V. Rezelj, Benoit Baron, Vitalija van Paassen, Javier Zaidman, Lee Fairlie, Gert Scheper, Mathieu Le Gars, Frank Struyf, Macaya Douoguih, Javier Ruiz-Guiñazú

“…We conducted a randomized, Phase 2 trial to assess the safety and humoral immunogenicity of reduced doses/dose volume of the standard dose of Ad26.COV2.S COVID-19 vaccine (5 × 1010 viral particles [vp]) in healthy adolescents aged 12–17 years. …”
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Angiotensin receptor neprilysin inhibition versus individualized RAAS blockade: design and rationale of the PARALLAX trial by Rolf Wachter, Sanjiv J. Shah, Martin R. Cowie, Peter Szecsödy, Victor Shi, Ghionul Ibram, Ziqiang Zhao, Jianjian Gong, Sven Klebs, Burkert Pieske

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Grounds and conditions for the application of preventive measures during the pre-trial investigation of corruption criminal offenses by V. V. Romaniuk, R. I. Login

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Comparison of Ticagrelor and Clopidogrel in Elective Coronary Stenting: A Double Blind Randomized Clinical Trial by Mohammadjavad Mehdizadeh Parizi, Reza Golchin Vafa, Amin Ahmadi, Reza Heydarzade, Mehrdad Sadeghi, Amin Khademolhossseini, Farhang Amiri, Soroush Khoshnood Mansorkhani, Ali Tavan, Nazanin Hosseini, Mohammad Montaseri, Seyed Ali Hosseini, Javad Kojuri

“…This randomized clinical trial was conducted from October 2022 to March 2023. …”
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Reconstruction by Pancreaticogastrostomy versus Pancreaticojejunostomy following Pancreaticoduodenectomy: A Meta-Analysis of Randomized Controlled Trials by YinFeng Shen, WenYin Jin

“…Published data of randomized clinical trials (RCTs) comparing the clinically relevant outcomes of PG versus PJ after PD were analyzed. …”
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Simulation of clinical trials of oral treprostinil in pulmonary arterial hypertension using a virtual population by Andrew E. Stine, Jignesh Parmar, Amy K. Smith, Zachary Cummins, Narasimha Rao Pillalamarri, R. Joseph Bender

“…We also demonstrated the virtual trial workflow’s potential for enriching populations based on clinical biomarkers to increase likelihood of trial success.…”
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Determining First Aid Knowledge and Skills Retention with Laypeople: A Randomized Controlled Trial in Nepal

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Lidocaine Infusion for the Management of Postoperative Pain and Delirium (LIMPP): protocol for a randomised control trial by Matthias Behrends, Marc Alan Buren, Alekos Theologis, Ariadne Zuraek, Aaron J Clark, Jacqueline M Leung

“…Participants wishing to know the results of this study will be contacted directly on data publication.Trial registration number NCT05010148.…”
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Correction: Internet-Based Supportive Interventions for Family Caregivers of People With Dementia: Randomized Controlled Trial by Yanhong Xie, Shanshan Shen, Caixia Liu, Hong Hong, Huilan Guan, Jingmei Zhang, Wanqi Yu

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Myriads of updated systematic reviews and meta-analyses - Should trial sequential and power-analysis be mandatory? by Habib M. R. Karim, Dalim K. Baidya, Rakesh Garg

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Efficacy of Memantine, Donepezil, or Their Association in Moderate-Severe Alzheimer’s Disease: A Review of Clinical Trials by Ivana Molino, Luisa Colucci, Angiola M. Fasanaro, Enea Traini, Francesco Amenta

“…This paper has reviewed evidence from clinical trials of the effectiveness of memantine, donepezil, or the two drugs in association in managing moderate-severe AD. …”
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Recent Advances in Dipeptidyl-Peptidase-4 Inhibition Therapy: Lessons from the Bench and Clinical Trials by Jixin Zhong, Quan Gong, Aditya Goud, Srividya Srinivasamaharaj, Sanjay Rajagopalan

“…Further, a signal of heart failure hospitalization in a recent large scale clinical trial SAVOR-TIMI 53 has called into question the safety of these agents and their utility in the treatment of cardiovascular disease. …”
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Effectiveness of Three Types of Moisturizers on Senile Dry Skin: A Randomized Controlled Pilot Trial by Miku Aoki, Natsuki Hata, Junko Yotsuya

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Effects of Metformin Added to Insulin in Adolescents with Type 1 Diabetes: An Exploratory Crossover Randomized Trial by Daizhi Yang, Jinhua Yan, Hongrong Deng, Xubin Yang, Sihui Luo, Xueying Zheng, Jing Lv, Wen Liang, Mengjie Hong, Zekai Wu, Bin Yao, Jianping Weng, Wen Xu

“…This was an exploratory, crossover, randomized trial conducted in adolescents with type 1 diabetes aged 12-18 years old. …”
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The Effect of the Platelet Administration for the Patients with Liver Dysfunction after Liver Resection: Preliminary Clinical Trial by Hui Xu, Yu-Mei Li, Yongxiang Yi, Yun-Wen Zheng, Nobuhiro Ohkohchi

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