Towards the standardization of Hydra vulgaris bioassay for toxicity assessments of liquid samples by G. Farley, P. Bouchard, C. Faille, S. Trottier, F. Gagné

“…The influence of 8 different analysts, the trial days and luminosity did not significantly influence the LC50 and EC50. …”
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Inhibitory Effects of iPSC-MSCs and Their Extracellular Vesicles on the Onset of Sialadenitis in a Mouse Model of Sjögren’s Syndrome by Bo Hai, Taeko Shigemoto-Kuroda, Qingguo Zhao, Ryang Hwa Lee, Fei Liu

“…Systemic infusion of allogeneic mesenchymal stem cells (MSCs) isolated from tissues such as bone marrow (BM) alleviated SS in mouse models and a small clinical trial, but further research and application of this MSC therapy were hindered by limited expandability, significant donor variations, and safety concerns of tissue-derived MSCs. …”
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Serial Assessment of Immune Status by Circulating CD8+ Effector T Cell Frequencies for Posttransplant Infectious Complications by Shinji Uemoto, Kazue Ozawa, Hiroto Egawa, Yasutsugu Takada, Hiroshi Sato, Satoshi Teramukai, Mureo Kasahara, Kohei Ogawa, Masako Ono, Kenji Takai, Masanori Fukushima, Kayo Inaba, Koichi Tanaka

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Shared genetics between breast cancer and predisposing diseases identifies novel breast cancer treatment candidates by Panagiotis N. Lalagkas, Rachel D. Melamed

“…Some drugs for other conditions, such as metformin, an antidiabetic, have been tested in clinical trials for repurposing for breast cancer. Here, we exploit the genetics of breast cancer and linked predisposing diseases to propose novel drug repurposing opportunities. …”
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Pigtail Catheter: A Less Invasive Option for Pleural Drainage in Egyptian Patients with Recurrent Hepatic Hydrothorax by Mohamed Sharaf-Eldin, Adel Salah Bediwy, Abdelrahman Kobtan, Sherief Abd-Elsalam, Ferial El-Kalla, Loai Mansour, Walaa Elkhalawany, Mohamed Elhendawy, Samah Soliman

“…Pigtail catheter insertion is a practical method for treatment of recurrent hepatic hydrothorax with a low rate of complications. This trial is registered with ClinicalTrials.gov Identifier: NCT02119169.…”
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Endoscopic tympanoplasty type I using interlay technique by Masahiro Takahashi, Masaomi Motegi, Kazuhisa Yamamoto, Yutaka Yamamoto, Hiromi Kojima

“…Further study of the postoperative outcomes of this procedure should be conducted to establish the optimal surgical procedure for tympanic perforations. Trial registration: This study was retrospectively approved by the Institutional Review Board of the Jikei University, Tokyo, Japan (approval number: 32-205 10286). …”
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La reforma eléctrica: El régimen apropiado by Mariano Rojas, Yolanda Cue

“…Además, se encuentra que el contextoeconómico y político de un país desempeña un papel fundamental en el efec -to de una re for ma re gu la to ria en el pro ce so in dus trial. Por ello, se con clu yeque no hay uni ver sa li dad en los be ne fi cios o per jui cios de una re for ma re gu -latoria.Se rea li za tam bién una si mu la ción de cuál se ría el efec to de una re for maregulatoria en el desempeño de la industria eléctrica en México. …”
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Home Availability and the Impact of Weekly Stressful Events Are Associated with Fruit and Vegetable Intake among African American and Hispanic/Latina Women by Tracey A. Ledoux, Scherezade K. Mama, Daniel P. O'Connor, Heather Adamus, Margaret L. Fraser, Rebecca E. Lee

“…Three hundred nine AA and HL, 25–60 year old women in the Health Is Power (HIP) randomized controlled trial completed validated measures of HAFV, IWSE, and FV intake at baseline. …”
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Nutrient Budget and Economic Assessment of Blended Fertilizer Use in Kenya Tea Industry by Kibet Sitienei, Hellen W. Kamiri, Gilbert M. Nduru, David M. Kamau

“…The sites were selected purposefully, one in the eastern and the other in the western tea-growing areas. The trial was laid out in randomized complete block design with two fertilizer blends and the standard NPK 26 : 5 : 5 as control. …”
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Day Ward Glaucoma Patients Have Lower Depression Levels and Higher Glaucoma Knowledge Levels than Inpatients by Huiming Xiao, Wenmin Huang, Xi Qin, Chengguo Zuo, Qiongman Yang, Rong Li, Mingkai Lin

“…Design. Randomized clinical trial. Participants. Consecutive patients undergoing surgery were prospectively enrolled. …”
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Exploring the Effects of a Neck Strengthening Program on Purposeful Soccer Heading Biomechanics and Neurocognition by Katelyn M. Waring, Edward R Smith, Gary P Austin, Thomas G Bowman

“… # Study Design Randomized controlled trial. # Methods Twenty collegiate soccer athletes (8 males, 12 females, age=20.15±1.35 years, height=171.67±9.01 cm, mass=70.56±11.03 kg) volunteered to participate. …”
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Adapting to ulcerative colitis to try to live a ‘normal’ life: a qualitative study of patients’ experiences in the Midlands region of England by Rachel Cooney, Christel McMullan, Dmitri Nepogodiev, Laura Magill, Thomas D Pinkney, Jonathan M Mathers, Laura L Jones, Shri Pathmakanthan

“…Further research around the utility of this framework in clinical practice and research is now required.Trial registration number ISRCTN56523019, results.…”
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Comparing apples and oranges in youth depression treatments? A quantitative critique of the evidence base and guidelines by Samuele Cortese, Glyn Lewis, Argyris Stringaris, Georgina Krebs, Marinos Kyriakopoulos, Lucy Foulkes, Carmen Moreno, Charlotte Burman, Raphaelle Delpech, Rudolph Uher, Dayna Bhudia, Despoina Miliou, Ioannis-Marios Rokas

“…Using meta-analyses, we compared (a) participant characteristics and (b) trial characteristics in medication and psychotherapy trials. …”
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Productivity of selection numbers of perennial ryegrass (Lolium perenne L.) in the nursery of competitive variety testing by Volodymyr Oleksiak, Lesia Baistruk-Hlodan, Oleg Stasiv, Hryhorij Konyk

“…In the competitive variety trial for haymaking, 2 selection numbers of perennial ryegrass (PFZ 02082 and PFZ 02514) were distinguished by plant height; 4 numbers – by leafiness (PFZ 02082; PFZ 02136; PFZ 02320; PFZ 02514), 2 numbers (PFZ 02082; PFZ 02514), 2 numbers – by green mass yield (PFZ 02082; PFZ 02514), and 2 numbers (PFZ 02082; PFZ 02514) – by dry matter yield. …”
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Admission Hyperglycemia and Acute Myocardial Infarction: Outcomes and Potential Therapies for Diabetics and Nondiabetics by Anjan K. Chakrabarti, Priyamvada Singh, Lakshmi Gopalakrishnan, Varun Kumar, Meagan Elizabeth Doherty, Cassandra Abueg, Weici Wang, C. Michael Gibson

“…There are a number of reasons that these trials may have fallen short, including the inability to reach glucose targets and inadequate power. …”
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Cost-effectiveness analysis of durvalumab with chemotherapy and maintenance durvalumab with or without olaparib for advanced endometrial cancer by Jiahao Zhang, Jianying Lei, Caicong You, Wu Fu, Bin Zheng, Hongfu Cai, Maobai Liu, Na Li

“…A Markov model based on DUO-E Phase III trial data simulated disease progression and outcomes. …”
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Comparison of 9.0 and 9.2 mm Flap Diameter Options of Femtosecond Laser In-Situ Keratomileusis for Hypermetropia and Hypermetropic Astigmatism by Kemal Ozulken, Cagri Ilhan

“…This study was registered with trial registration number 118-011.…”
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Use of digital data from open sources during the investigation of criminal offenses: certain aspects by Basysta I., Havrylyuk L., Hutnyk A., Khytra A.

“…The results of the research can be used in the course of a pre-trial investigation when there is a need to “work” with open sources of digital information.…”
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Intestinal microbiota is altered in patients with colon cancer and modified by probiotic intervention by Ashley A Hibberd, Anna Lyra, Arthur C Ouwehand, Peter Rolny, Helena Lindegren, Lennart Cedgård, Yvonne Wettergren

“…Our results show promise for potential therapeutic benefits in CRC by manipulation of the microbiota.Trial registration number NCT03072641; Results.…”
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Myoelectric pattern recognition with virtual reality and serious gaming improves upper limb function in chronic stroke: a single case experimental design study by Maria Munoz-Novoa, Morten B. Kristoffersen, Katharina S. Sunnerhagen, Autumn Naber, Max Ortiz-Catalan, Margit Alt Murphy

“…Conclusions MPR combined with VR and serious gaming is a feasible and promising intervention for improving upper limb function in people with chronic stroke. Trial Registration: ClinicalTrials.gov, reference number NCT04154371.…”
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