Risk Factors Analysis of Cutaneous Adverse Drug Reactions Caused by Targeted Therapy and Immunotherapy Drugs for Oncology and Establishment of a Prediction Model by Zimin Zhang, Mingyang Zhu, Weiwei Jiang

“…These findings have important implications for optimizing therapeutic efficacy and maintaining the quality of life of patients from the perspective of managing cutaneous adverse drug reactions. Trial Registration: ChiCTR2400088422…”
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Monitoring benthic plumes, sediment redeposition and seafloor imprints caused by deep-sea polymetallic nodule mining by Iason-Zois Gazis, Henko de Stigter, Jochen Mohrmann, Karl Heger, Melanie Diaz, Benjamin Gillard, Matthias Baeye, Mario E. Veloso-Alarcón, Kaveh Purkiani, Matthias Haeckel, Annemiek Vink, Laurenz Thomsen, Jens Greinert

“…Abstract A deep-sea (4500 m) trial of a pre-prototype polymetallic nodule collector with independent scientific monitoring revealed that a gravity current formed behind the collector channeled through steeper seafloor sections and traveled 500 m downslope. …”
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Machine learning based quantitative pain assessment for the perioperative period by Gayeon Ryu, Jae Moon Choi, Hyeon Seok Seok, Jaehyung Lee, Eun-Kyung Lee, Hangsik Shin, Byung-Moon Choi

“…These results highlight the models’ effectiveness in pain assessment throughout the surgical process, identifying waveform skewness and diastolic phase rate decrease as critical for intraoperative pain assessment and systolic phase area or baseline fluctuation as significant for postoperative pain assessment. Clinical trial registration: Registration name: Clinical Research Information Service (CRIS). …”
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Efficacy of green tea mouth wash as an adjunct to non-surgical periodontal treatment in patients with chronic periodontitis by Sarwar Qasim Mustafa, Dilyar Ahmed Baban

“…Patients and methods: A randomized controlled trial on 45 healthy humans with mild to moderate localized chronic periodontitis. …”
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Innovative gamification strategies to improve student learning outcomes in vocational high schools by Muhammad Iqbal Faza, Ranu Iskandar, Rizqi Fitri Naryanto

“…Validation of this gamification learning media was carried out by linguists, material experts, and media experts. The trial was conducted on students of class XI TKR 1 and 2 at Mataram Semarang Vocational High School, with a total of 61 students. …”
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Development of an expectation management intervention for patients with Long COVID: A focus group study with affected patients. by Manuel Funk, Max Reinke, Bernd Löwe, Petra Engelmann

“…The study results informed the finalization of the treatment manual within the SOMA.COV project, which investigates the effectiveness of this intervention for patients with Long COVID in a three-armed randomized controlled trial.…”
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The role of glucagon-like peptide-1 receptor (GLP-1R) agonists in enhancing endothelial function: a potential avenue for improving heart failure with preserved ejection fraction (H... by Darshan Hullon, Ghasaq K. Subeh, Yelizaveta Volkova, Karolina Janiec, Adam Trach, Ruslan Mnevets

“…GLP-1R agonists, including semaglutide and liraglutide, have demonstrated significant cardioprotective effects, such as improving vascular endothelial function, reducing inflammation, and preventing atherosclerosis. Clinical trials, such as the STEP-HFpEF trial, have shown positive results in reducing symptoms and physical restrictions in HFpEF patients. …”
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Development and evaluation of winter barley varieties for group resistance to smut diseases by I. B. Legkun

“…In doing this, we tried the following method: natural infection with local populations of false loose smut (Ustilago nigra) and covered smut (Ustilago hordei) against artificial background (in the field) followed by the test (invasive) assessment of the variety samples at the stage of competitive variety trial.…”
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Chronic kidney disease among people living with HIV on TDF based regimen: A systematic review and meta-analysis. by Taklo Simeneh Yazie, Wondimeneh Shibabaw Shiferaw, Asaye Alamneh Gebeyehu, Assefa Agegnehu Teshome, Zenaw Debasu Addisu, Abebe Muche Belete

“…Early identification of CKD by considering regular renal function monitoring, and risk factors especially low CD4 count, and female gender at birth are essential.<h4>Trial registration</h4>The protocol has been prospectively registered with PROSPERO ((CRD42020136813).…”
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Protocol for a cluster randomized study to compare the effectiveness of a self-report distress tool and a mental health referral service to usual case management on program complet... by Shawna Bailey, Carrie Stoner, Kelly Cruise, Giulio DiDiodato

“…<h4>Outcomes</h4>The primary outcome includes: 1) Difference in proportion of absence-free program days from date of randomization, where absence-free days are defined as being present in class or work setting for ≥ 8 hours from Monday to Thursday during the 12-week program duration.<h4>Trial registration</h4>ClinicalTrials.gov NCT05626374 (November 23, 2022).…”
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Predictors of Instrumental Activities of Daily Living Performance in Patients with Stroke by Amin Ghaffari, Hamid Reza Rostami, Malahat Akbarfahimi

“…Age (r=−0.384, p<0.001), memory (r=0.565, p<0.001), basic activities of daily living (r=0.818, p<0.001), depression (r=−0.758, p<0.001), Trial Making Test (B-A) (r=−0.614, p<0.001), and motoricity index (r=0.670, p<0.001) were significantly associated with instrumental activities of daily living performance. …”
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Restoration of Central Programmed Movement Pattern by Temporal Electrical Stimulation-Assisted Training in Patients with Spinal Cerebellar Atrophy by Ying-Zu Huang, Yao-Shun Chang, Miao-Ju Hsu, Alice M. K. Wong, Ya-Ju Chang

“…This technique may be applied to treat hypermetria in cerebellar disorders. (This trial is registered with NCT01983670.)…”
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Effect of Bronchoscopist-Directed Sedation and Other Factors on Patient Comfort during Diagnostic Flexible Bronchoscopy by Rahul Magazine, Keerthi Nedumala Sisupalan, Vyshak Uddur Surendra, Bharti Chogtu, Preetam Rajgopal Acharya, Vasudeva Guddattu

“…This study is registered with the Clinical Trial Registry of India (CTRI/2018/11/016328).…”
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Comparison of Intervention Programs to Improve Trunk Stability for Active Females by Kate Schwartzkopf-Phifer, Katie Whetstone, Mark Marchino, Kevin Brown, Kyle Matsel

“… # Study Design Randomized controlled trial # Methods All subjects were tested at baseline on Beighton criteria, the FMSTM, Y-Balance Test Upper Quarter and Lower Quarter, and grip strength by an evaluator blinded to group allocation. …”
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PENGEMBANGAN MODUL BRYOPHYTA BERBASIS HASIL PENELITIAN DI TAHURA NGARGOYOSO KARANGANYAR UNTUK SISWA KELAS X SMA by Acna Clara Aida Wati, Tri Wiharti, Anwari Adi Nugroho

“…This type of research is research and developer according to Brog and Gall which was modified into 7 stages, among others is 1) research and information gathering; 2) planning; 3) initial product development; 4) trial of initial product; 5) initial product revision; 6) limited field testing; 7) second product revision. …”
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A Supportive-Educational Intervention for Heart Failure Patients in Iran: The Effect on Self-Care Behaviours by Vahid Zamanzadeh, Leila Valizadeh, A. Fuchsia Howard, Fatemeh Jamshidi

“…This research was a prospective, randomized trial of a supportive-educational intervention. Eighty heart failure patients were randomly assigned to receive the supportive-educational intervention or usual care. …”
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A high-fat meal significantly impacts the bioavailability and biphasic absorption of cannabidiol (CBD) from a CBD-rich extract in men and women by Bo Anne Daniëlla Frederique Saals, Tessa Helena De Bie, Eral Osmanoglou, Ties van de Laar, Adriaan Willem Tuin, Anne Claire Benedikte van Orten-Luiten, Renger Frederik Witkamp

“…This contributes to sustained high plasma concentrations and may be (partially) attributed to lymphatic transport, enterohepatic recirculation, and/or a secondary meal effect. This trial was registered on October 19, 2020, with ClinicalTrials.gov under the identifier NCT04589455. …”
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Effect of Intra-Articular Hyaluronic Injection on Postural Stability and Risk of Fall in Patients with Bilateral Knee Osteoarthritis by Nafiseh Khalaj, Noor Azuan Abu Osman, Abdul Halim Mokhtar, John George, Wan Abu Bakar Wan Abas

“…This study illustrated that five intra-articular hyaluronic acid injections could significantly improve postural stability and fall risk in bilateral knee osteoarthritis patients. This trial is registered with: NCT02063373.…”
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Arginine–NO pathway modulated energy metabolism in the hepatopancreas and muscle of female Litopenaeus vannamei by Haitao Fan, Xin Zhang, Yanan Yin, Lefei Jiao

“…Accordingly, an eight-week feeding trial was conducted to confirm it in female Litopenaeus vannamei. …”
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Efficacy of Sub-Conjunctival Injection of Mitomycin C Versus Bevacizumab in Pterygium Treatment: Pakistani Population by Amber khalid, Sharjeel Sultan, Aveen Fatima, Ayesha Khalid, Maryam Shifa

“…Methods: The Randomized clinical trial was conducted in the Ophthalmology department of Ziauddin University over 8 months. 54 patients aged above 18 with grade 2 or 3 pterygium were divided into 2 groups of 27. …”
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