Oncologic oUTcomes of neoadjuvant chemotherapy for obSTructive colon cAncer after steNt decompression (OUTSTAND trial); A study protocol of multicenter non-inferiority randomized controlled trial by Bong-Hyeon Kye, Ji-Hoon Kim, Hyung-Jin Kim, Yoon-Suk Lee, In-Kyu Lee, Won Kyung Kang, Hyeon-Min Cho, Jong-Kyung Park, Chang-Hyeok Ahn, Jae-Im Lee, Seong-Taek Oh, Byung Jo Choi

“…Based on the results of this trial, a patient-tailored treatment strategy can be developed for obstructive colon cancer. …”
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Weight loss for overweight and obese patients with prostate cancer: a study protocol of a randomised trial comparing clinic-based versus Telehealth delivered EXercise and nutrition intervention (the TelEX trial) by Robert U Newton, Daniel A Galvão, Dennis R Taaffe, Suzanne K Chambers, David Joseph, Amanda Devine, Colin I Tang, Nigel Spry, Emily Jeffery, Dickon Hayne, Pedro Lopez, P Lyons-Wall, Christine Kudiarasu

“…Outcomes from the study will be published in academic journals and presented in scientific and consumer meetings.Trial registration number ACTRN12621001312831.…”
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Does digital, multimedia information increase recruitment and retention in a children’s wrist fracture treatment trial, and what do people think of it? A randomised controlled Study Within A Trial (SWAT) by Jacqueline M Martin-Kerry, Peter Knapp, Steven Higgins, Rebecca Sheridan, Juul Achten, Duncan Appelbe, Louise Spoors, Thirimon Moe-Byrne, Daniel Perry, Jenny Roche

“…Objectives To evaluate digital, multimedia information (MMI) for its effects on trial recruitment, retention, decisions about participation and acceptability by patients, compared with printed information.Design Study Within A Trial using random cluster allocation within the Forearm Fracture Recovery in Children Evaluation (FORCE) study.Setting Emergency departments in 23 UK hospitals.Participants 1409 children aged 4–16 years attending with a torus (buckle) fracture, and their parents/guardian. …”
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Effect of Folic Acid Supplementation in Pregnancy on Preeclampsia: The Folic Acid Clinical Trial Study by Shi Wu Wen, Josee Champagne, Ruth Rennicks White, Doug Coyle, William Fraser, Graeme Smith, Dean Fergusson, Mark C. Walker

“…The Effect of Folic Acid Supplementation in Pregnancy on Preeclampsia: the Folic Acid Clinical Trial (FACT) aims to recruit 3,656 high risk women to evaluate a new prevention strategy for PE: supplementation of folic acid throughout pregnancy. …”
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Wet Laboratory Versus Computer Simulation for Learning Endobronchial Ultrasound: A Randomized Trial by David R Stather, Paul MacEachern, Alex Chee, Elaine Dumoulin, Christopher A Hergott, Alain Tremblay

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The use of technology in civil and family oral trials as an innovative source of human rights in Mexico by Dra. Blanca Torres Espinosa, Carlos Ernesto Arcudia Hernández, Sara Berenice Orta Flores

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Generalizability of Randomized Clinical Trial Outcomes for Diabetes Control Resulting From Bariatric Surgery by Edward H. Livingston, MD, FACS, AGAF, Hila Zelicha, RD, PhD, Erik P. Dutson, MD, Zhaoping Li, MD, PhD, Matthew L. Maciejewski, PhD, Yijun Chen, MD

“…To assess the external validity of randomized controlled trials (RCTs) of bariatric surgical treatment on diabetes control. …”
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A Simple Matter of Life and Death—The Trials of Postnatal Beta-Cell Mass Regulation by Elena Tarabra, Stella Pelengaris, Michael Khan

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Gestational Weight Gain: Results from the Delta Healthy Sprouts Comparative Impact Trial by Jessica L. Thomson, Lisa M. Tussing-Humphreys, Melissa H. Goodman, Sarah E. Olender

“…Delta Healthy Sprouts trial was designed to test the comparative impact of two home visiting programs on weight status, dietary intake, and health behaviors of Southern African American women and their infants. …”
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Effects of movement behaviors on preschoolers’ cognition: a systematic review of randomized controlled trials by Catalina Pacheco, Victoria Culkin, Amelia Putkaradze, Nan Zeng

“…We conducted a systematic review of randomized controlled trials (RCTs) to evaluate the impact of interventions targeting PA, SB, and sleep on cognitive outcomes in preschool-aged children. …”
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Clinical outcomes of atrial fibrillation screening: a meta-analysis of randomized controlled trials by Ville Langén, Aleksi K. Winstén, K. E. Juhani Airaksinen, Konsta Teppo

“…Background Several randomized controlled trials (RCTs) have investigated the benefits of atrial fibrillation (AF) screening. …”
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A cost/benefit analysis of clinical trial designs for COVID-19 vaccine candidates. by Donald A Berry, Scott Berry, Peter Hale, Leah Isakov, Andrew W Lo, Kien Wei Siah, Chi Heem Wong

“…We compare and contrast the expected duration and number of infections and deaths averted among several designs for clinical trials of COVID-19 vaccine candidates, including traditional and adaptive randomized clinical trials and human challenge trials. …”
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Open Trial of Cyclosporine in Patients with Severe Active Crohn's Disease Refractory to Conventional Therapy by Kevork M. Peltekian, C. Noel Williams, Allan S. MacDonald, Peter D. Roy, Elizabeth Czolpinska

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Whole-body photobiomodulation therapy for chronic pain: a protocol for a feasibility trial by Nicola R Heneghan, Andrew Soundy, Bethany Fitzmaurice, Asius Rayen

“…Outcome measures will focus on acceptability of trial processes with a view to guiding a definitive randomised controlled trial. …”
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Long-term engagement in smoking cessation campaign: A mixed methods randomized trial. by Robert Schwartz, Tracey Borland, Maaz Shahid, Karen Kuzmich, Michael Chaiton

“…The intervention also allows for real-time learning to support campaign development.<h4>Trial registration</h4>ISRCTN94797633.…”
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Safety, Immunogenicity, and Efficacy of Cytomegalovirus Vaccines: A Systematic Review of Randomized Controlled Trials by Manuela Chiavarini, Anita Genga, Giorgia Maria Ricciotti, Marcello Mario D’Errico, Pamela Barbadoro

“…<b>Methods</b>: According to the PRISMA guidelines (PROSPERO ID: CRD42024516601), a comprehensive literature search was conducted to identify all the randomized controlled trials that have evaluated the safety, immunogenicity, and efficacy of vaccine candidates compared to a placebo. …”
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Selective dry cow therapy: Clinical field trial on prevention and cure of intramammary infections by R.E. Niemi, M. Hovinen, P.J. Rajala-Schultz

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Upper Extremity Function following Transradial Percutaneous Coronary Intervention: Results of the ARCUS Trial by Eva M. Zwaan, Elena S. Cheung, Alexander J. J. IJsselmuiden, Carlo A. J. Holtzer, Ton A. R. Schreuders, Marcel J. M Kofflard, J. Henk Coert

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Initial Clinical Trial of Robot of Endovascular Treatment with Force Feedback and Cooperating of Catheter and Guidewire by Yuhua Jiang, Keyun Liu, Youxiang Li

“…No obvious abnormality was observed in the examination of patients’ check-up, head nuclear magnetism, and blood routine after the digital subtraction angiography. From this clinical trial, it can be observed that the robot system can perform the operation of cerebral angiography. …”
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The Effect of Probiotics on Childhood Constipation: A Randomized Controlled Double Blind Clinical Trial by M. Sadeghzadeh, A. Rabieefar, P. Khoshnevisasl, N. Mousavinasab, K. Eftekhari

“…In this placebo controlled trial, fifty-six children aged 4–12 years with constipation received randomly lactulose plus Protexin or lactulose plus placebo daily for four weeks. …”
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