Alternative Approach for Combination of Fingers in Underwater Acoustic Communication by Ji-Hong Son, Eun-Hye Jeon, Ki-Man Kim, Dong-Won Lee, Tae-Doo Park

“…We conducted simulations and lake trials to evaluate the performance of the proposed method. …”
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Robust Sliding Mode Control of Robot Manipulators Using the Fourier Series Expansion in the Presence of Uncertainty by Abdullah Hadipoor, Siamak Azargoshasb, Abdolrasool Ghasemi

“…Compared to previous related works based on the Fourier series expansion, the advantage of this paper is that it provides a matching law for the main frequency of the Fourier series expansion and thus eliminates the need for trial and error in its regulation. A case study of a Scara robot powered by DC magnet electric motors. …”
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A Reward Optimization Method Based on Action Subrewards in Hierarchical Reinforcement Learning by Yuchen Fu, Quan Liu, Xionghong Ling, Zhiming Cui

“…Its main characteristics are “trial and error” and “related reward.” A hierarchical reinforcement learning method based on action subrewards is proposed to solve the problem of “curse of dimensionality,” which means that the states space will grow exponentially in the number of features and low convergence speed. …”
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Nested Variant of Urothelial Carcinoma by Anthony Kodzo-Grey Venyo

“…Correct and early diagnosis of this tumour is essential to provide early curative treatment to avoid diagnosis at an advanced stage. A multicentre trial is required to identify treatment options that would improve the outcome of this tumour.…”
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MODEL PREDICTIVE CONTROL FOR PHOTOVOLTAIC STATION MAXIMUM POWER POINT TRACKING SYSTEM by I. Elzein, Yu. N. Petrenko

“…The system under consideration consists of a solar array with nonlinear time-varying characteristics, a step-up converter with appropriate filter.The proposed algorithm has the advantages of maximizing the efficiency of the power utilization, can be integrated to other MPPT algorithms without affecting the PVM performance, is excellent for Real-Time applications and is a robust analytical method, different from the traditional MPPT algorithms which are more based on trial and error, or comparisons between present and past states. …”
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Promising Remission with Reduced Bevacizumab and Pembrolizumab Dosage in a Patient with AT-rich Interaction Domain 1A Mutated Ovarian Clear-cell Carcinoma Refractory to Chemotherap... by Cheng-Wei Huang, Ruo-Han Tseng

“…The phase II KEYNOTE-100 trial revealed that pembrolizumab monotherapy demonstrated a 15.8% objective response in patients with ovarian clear-cell carcinoma in the subgroup analysis, which is much higher than that of other histology subtypes of ovarian cancer. …”
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Machine Learning Techniques for Quantification of Knee Segmentation from MRI by Sujeet More, Jimmy Singla, Ahed Abugabah, Ahmad Ali AlZubi

“…The review paper also focuses on automatic approaches and semiautomatic approaches which are extensively used with performance metrics and sufficient achievement for clinical trial assistance. Furthermore, the results of different approaches related to MR sequences used to image the knee tissues and future aspects of the segmentation are discussed.…”
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Study on the Production Factors in the Process of Production and Properties of Fly Ash-Based Coarse Aggregates by K. N. Shivaprasad, Bibhuti Bhusan Das

“…An optimization study was carried out for the sustainable production of coarse aggregates from fly ash and alkaline solution, considering the combined effect of alkaline solution and production process. The trial mixes during the process of producing the artificial aggregates were designed through Taguchi’s experimental design method. …”
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Vascular Endothelial Growth Factor (VEGF) Family and the Immune System: Activators or Inhibitors? by Cristina Maria Failla, Maria Luigia Carbone, Carmela Ramondino, Emanuele Bruni, Angela Orecchia

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The Role of the PGC1α Gly482Ser Polymorphism in Weight Gain due to Intensive Diabetes Therapy by Samir S. Deeb, John D. Brunzell

“…The Diabetes Control and Complications Trial (DCCT) involved intensive diabetes therapy of subjects with type 1 diabetes mellitus (T1DM) for an average period of 6.5 years. …”
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Neoadjuvant anti-PD-1-based immunotherapy: evolving a new standard of care by Drew M Pardoll, Suzanne L Topalian

“…Neoadjuvant (presurgical) anti-programmed cell death protein-1 (PD-1)-based immunotherapy as a new approach to cancer treatment has been developing on an accelerated trajectory since the seminal clinical trial results from studies in lung cancer and melanoma were published in 2018. …”
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Earlier Intervention with Deep Brain Stimulation for Parkinson’s Disease by Gerson Suarez-Cedeno, Jessika Suescun, Mya C. Schiess

“…In 2013 the EARLY-STIM trial provided Class I evidence for the use of DBS earlier in Parkinson’s disease. …”
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Pole Allocation Applied to Two Buildings Connected by Joint Damper by Yoshiki Ikeda, Yuki Matsumoto

“…The integration of the pole allocation method and fixed-point theory directly estimates the additional damping effect on the target buildings from the optimum capacity of the joint damper, which improves the trial-and-error steps at the preliminary design stage. …”
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Fecal DNA Screening in Colorectal Cancer by Suzanne Richter

“…Current challenges include cost reduction and demonstration of mortality benefit in a rigorous clinical trial. Despite current challenges, fecal DNA testing is worth pursuing. …”
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Autologous Cord Blood Therapy for Infantile Cerebral Palsy: From Bench to Bedside by A. Jensen

“…Particularly, since the first published double-blind randomized placebo-controlled trial in a paradigm using allogeneic cord blood and erythropoietin to treat cerebral palsy under immunosuppression showed beneficial therapeutic effects in infantile cerebral palsy, long-held doubts about the efficacy of this new cell therapy are dispelled and a revision of therapeutic views upon an ailment, for which there is no cure at present, is warranted. …”
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Development of medication reminder WhatsApp Bot application to improve medication adherence in pregnant women with hypertension by Hesti Kurniasih, Septerina Purwandani Winarso, Qona Lutfi Sartika

“…Method: This study employed Research and development, which consisted of four stages: Literature Study, Development Stage, Validity Expert, and Trial. Results: A system that health workers can use in primary health facilities to remind them when to take medication has been successfully created. …”
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Bond Graph-Based Modelling and Control of Electromagnetic Levitation System Using Firefly Optimization by Ismail Dif, Naas Dif, Khier Benmahammed

“…To determine the controller parameters, we utilized a meta-heuristic method called Firefly for optimization, thus avoiding the need for trial and error. The simulation was conducted using 20-Sim software and a Matlab/Simulink script, which yielded improved results. …”
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The irreconcilability of insight by Eli Shupe

“…., causal cognition, or mental trial and error); and, second, that the relevant performances merely reflect associative learning—and on the received understanding of insight within comparative cognition, insight necessarily involves non-associative processes. …”
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Survey and perspective on verification, validation, and uncertainty quantification of digital twins for precision medicine by Kaan Sel, Andrea Hawkins-Daarud, Anirban Chaudhuri, Deen Osman, Ahmad Bahai, David Paydarfar, Karen Willcox, Caroline Chung, Roozbeh Jafari

“…We highlight challenges and opportunities for developing personalized trial methodologies, validation metrics, and standardizing VVUQ processes. …”
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CYP2A6 Polymorphisms May Strengthen Individualized Treatment for Nicotine Dependence by Yawo Mawuli Akrodou

“…., CYP2A6*1H, CYP2A6*4A, CYP2A6*9, and CYP2A6*12A) are associated with underrated nicotine metabolizing activity (50%–75%), linking them to low scores for nicotine dependence (0–4) on the FTND scale. In a clinical trial involving the use of bupropion, people who were carriers of slow nicotine metabolizers were found to have a tendency to maintain abstinence 1.7 times longer than people with normal nicotine metabolizers. …”
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