Regenerative fibroblasts derived from autologous skin tissue for the treatment of Sjögren’s syndrome: a case report by Zhao-Xia Ma, Xing-Fei Wu, Li Cao, Cheng-Yan Jiao, Dai-Ping Ma, Yun-Hui Zhao, Zhi-Xing Yang, Min Hu, Min Hu

“…No adverse effects were associated with the use of rFib in the volunteer during the clinical trial.SummaryThe results of this clinical trial indicate that intravenous injections of autologous rFib are both safe and effective for treating SS. …”
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Rapamycin-resistant polyclonal Th1/Tc1 cell therapy (RAPA-201) safely induces disease remissions in relapsed, refractory multiple myeloma by Lawrence G Lum, Parameswaran Hari, Aniko Szabo, Michele Donato, Jee Hyun Park, Daniel H Fowler, Binod Dhakal, Saurabh Chhabra, Deborah D Glass, David S Siegel, Tania C Felizardo

“…RAPA-201 therapy overcomes previous barriers to effective autologous polyclonal T-cell therapy, as it is feasible to manufacture, exquisitely safe to administer, and mediates remission in patients with RRMM.Trial registration number ClinicalTrials.gov: NCT04176380.…”
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Triglyceride lowering in patients with different severities of hypertriglyceridaemia-associated acute pancreatitis: secondary analysis of a multicentre, prospective cohort study by Xiaoling Li, Lin Gao, Xiang Luo, Wenjian Mao, Lu Ke, Xiaoyan Lai, Lingyan Fu, Yaolu Liu

“…Similar findings were seen in the subgroup with more severe HTG-AP (APACHE II ≥8 at enrolment).Conclusion More rapid decline of serum TG levels was associated with decreased presence of organ failure at day 14 in patients with more severe HTG-AP.Trial registration number The Chinese Clinical Trial Registry, number ChiCTR2000039541.…”
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Improving Outcomes and Quality of Life for Patients With Hand and Foot Eczema: Randomized Study of a Patient-Centered Monitoring App by Aimee Bruch, Wanja Weigandt, Yannic Schardt, Raphael Herr, Johannes Benecke, Astrid Schmieder

“…ConclusionsThis study provides further evidence that digital health apps can provide valuable support in improving patient clinical outcomes and management, especially as the app-based assessment of hand and feed images appears to be reliable. Trial RegistrationDeutsches Register Klinischer Studien DRKS00020963; https://drks.de/search/de/trial/DRKS00020963…”
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Transforaminal Endoscopic Lumbar Discectomy versus Coblation Nucleoplasty Combined with Collagenase Chemonucleolysis for Lumbar Disc Herniation with Grade I Degenerative Spondyloli... by Yuyu Guo, Liuhu Han, Tingting Li, Bingbing Xu, Penghui Ke, Jun Hu, Rongyi Zhang, Yan Guo, Long Zhao, Likui Wang

“…Compared with CN combined with CCNL, TELD had more significant improvement in early lower back and leg pain and shorter post-operative duration of hospitalization. Trial Registration The trial was registered on ClinicalTrials.gov (ChiCTR2300076809).…”
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Development and validation of soil test crop response model for beetroot (Beta vulgaris) grown in ultisols of India by Ramasamy Arulmani, Ramasamy Arulmani, Kuppayevalasu Malayappagounder Sellamuthu, Kuppayevalasu Malayappagounder Sellamuthu, Subramaniam Maragatham, Subramaniam Maragatham, Alargarsamy Senthil, Alargarsamy Senthil, Seenapuram Palaniswami Thamaraiselvi, Seenapuram Palaniswami Thamaraiselvi, Palaniappan Malathi, Palaniappan Malathi, Govindaraja Sridevi, Govindaraja Sridevi

“…Field trial includes a gradient experiment with a green viz., Chenopodium album; a test crop experiment with beetroot (Hybrid Improved Crystal) and a validation experiment with beetroot. …”
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Genotypic and ecological variability of zinc content in the grain of spring bread wheat varieties in the international nursery KASIB by V. P. Shamanin, P. Flis, T. V. Savin, S. S. Shepelev, O. G. Kuzmin, A. S. Chursin, I. V. Pototskaya, I. E. Likhenko, I. Yu. Kushnirenko, A. A. Kazak, V. A. Chudinov, T. V. Shelaeva, A. I. Morgounov

“…The research on screening zinc content in the wheat grain of 49 spring bread wheat varieties from the KazakhstanSiberia Spring Wheat Trial (KASIB) nursery was carried out at 4 sites in Russia (Chelyabinsk, Omsk, Tyumen, Novosibirsk) and 2 sites in Kazakhstan (Karabalyk and Shortandy) in 2017–2018. …”
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The bergen 4-day treatment for panic disorder: a longer-term follow-up by Thorstein Olsen Eide, Bjarne Hansen, Kay Morten Hjelle, Stian Solem, Michael G. Wheaton, Thröstur Björgvinsson, Gerd Kvale, Kristen Hagen

“…Method Thirty patients with panic disorder were consecutively included in a retrospect open trial. The primary outcome measure was the Panic Disorder Severity Scale. …”
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The impact of dietary phosphorus levels on growth, slaughter, and digestive metabolism in growing sheep by Shoupei Zhao, Xiaojun Ni, Jia Zhou, Xiaoqi Zhao, Xiao Wen, Xiaolin Wang, Mingyu Cao, Yanfei Zhao, Chong Shao, Lianghao Lu, Yuanyuan Chen, Bao Zhang, Huaming Yang, Bai Xue, Guobo Quan

“…Forty-five sheep (30.33 ± 0.56 kg) were randomly assigned to five dietary P levels (0.40, 0.51, 0.68, 0.82, and 0.97%) over a 44-day trial, including a 14-day pre-feeding and 30-day formal trial period. …”
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Leveraging Autofluorescence for Tumor Detection, Diagnosis, and Accurate Excision with Surgical Margin Assessment in Tumor Excision by Antonis Perdiou, Ramona Dumitrescu, Daniela Jumanca, Octavia Balean, Ruxandra Sava-Rosianu, Serban Talpos, Dacian Virgil Lalescu, Atena Galuscan

“…Ethical approval was obtained from the “Spitalul Clinic Municipal de Urgență Timișoara” Ethics Committee (approval number 08/26.02.2021), and the trial was registered at the University of Medicine and Pharmacy Timisoara (trial no. 59/25.11.2021). …”
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Durvalumab as consolidation therapy in patients who received chemoradiotherapy for unresectable stage III NSCLC: Real-world data from an expanded access program in Brazil (LACOG 01... by Mauro Zukin, Victor Gondim, Andrea Kazumi Shimada, Ellias Magalhães e Abreu Lima, Clarissa Mathias, Williams Fernandes Barra, William Nassib William Junior, Mônica Padoan, Yuri Bittencourt, Rosely Yamamura, Carlos Eduardo Baston Silva, Letícia de Jesus Rossato, Caio de Almeida Monteiro, Rafaela Gomes de Jesus, Gustavo Gössling, Ana Caroline Zimmer Gelatti

“…ABSTRACT Objective: The PACIFIC trial established standard therapy for patients with unresectable stage III NSCLC who did not progress after platinum-based concurrent chemoradiation therapy. …”
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Acute effect of endurance exercise on human milk insulin concentrations: a randomised cross-over study by Rebecca Lyng Holm, Mads Holmen, Md Abu Jafar Sujan, Md Abu Jafar Sujan, Guro F. Giskeødegård, Trine Moholdt, Trine Moholdt

“…Future research should determine the effect of regular exercise on insulin in human milk and potential impact for infant health outcomes.Clinical trial registrationClinicalTrials.gov, identifier NCT05042414.…”
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Research on Monitoring Methods for the Appropriate Rice Harvest Period Based on Multispectral Remote Sensing by Chen Cong, Cao Guangqiao, Li Yibai, Liu Dong, Ma Bin, Zhang Jinlong, Li Liang, Hu Jianping

“…The continuous monitoring of two rice varieties (South Japonica 46 and South Japonica 5055) indicated that the moisture content of South Japonica 46 decreased linearly during the 20-day trial period, while its thousand-grain weight showed a trend of increasing first and then decreasing. …”
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Time without PSA recurrence after radical prostatectomy as a predictor of future biochemical recurrence, metastatic disease and prostate cancer death: a prospective Scandinavian co... by Mats Steinholtz Ahlberg, Hans-Olov Adami, Hans Garmo, Lars Holmberg, Anna Bill-Axelson, Ove Andren, Gunnar Steineck, Jan-Erik Johansson

“…Stratification by Gleason score (≤3+4=7 or ≥4+3=7), pathological tumour stage (pT2 or ≥pT3) and negative or positive surgical margins.Setting Between 1989 and 1998, 14 urological centres in Scandinavia randomised patients to the Scandinavian Prostate Cancer Group study number 4 (SPCG-4) trial.Participation All 306 patients from the SPCG-4 trial who underwent radical prostatectomy within 1 year from inclusion were eligible. …”
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Risk Factors Associated with Cardiac Autonomic Modulation in Obese Individuals by Camila Oliveira, Erika Aparecida Silveira, Lorena Rosa, Annelisa Santos, Ana Paula Rodrigues, Carolina Mendonça, Lucas Silva, Paulo Gentil, Ana Cristina Rebelo

“…The present study is a cutout of a randomized clinical trial “Effect of nutritional intervention and olive oil in severe obesity” (DieTBra Trial), where the baseline data were analyzed. …”
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Using peer narrative support to promote return to work for cancer survivors: a protocol study of action research by Wenqian Que, Xiaoyun Hu, Tingting Wu, Haiyin Zhang, Yue Shi, Jingyi Zhao, Xiaoqin Su, Benxin Kuai, Yujie Guo

“…This will provide scientific guidance for the Chinese Cancer Rehabilitation Association to develop peer narrative support and guide cancer survivors back to work. Trial registration This study has been registered at the Chinese Clinical Trial Registry (Registration number ChiCTR2300068403) on Feb 17, 2023. …”
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Preoxygenation in difficult airway management: high-flow oxygenation by nasal cannula versus face mask (the PREOPTIDAM study). Protocol for a single-centre randomised study by Samir Jaber, Karim Asehnoune, Fanny Feuillet, Mickael Vourc’h, Donatien Huard, Gabrielle Baud, Arthur Guichoux, Marielle Surbled, Melanie Tissot, Anne Chiffoleau, Christophe Guitton

“…Results will be submitted to international peer-reviewed medical journals.Trial registration number NCT03604120.…”
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Effect and Safety of Transcutaneous Auricular Vagus Nerve Stimulation on Recovery of Upper Limb Motor Function in Subacute Ischemic Stroke Patients: A Randomized Pilot Study by Dandong Wu, Jingxi Ma, Liping Zhang, Sanrong Wang, Botao Tan, Gongwei Jia

“…This study revealed that taVNS appeared to be beneficial to the recovery of upper limb motor function in subacute ischemia stroke patients without obvious adverse effects. Trial registration. This trial is registered with ChiCTR1800019635 on 20 November 2018 (http://www.chictr.org.cn/showproj.aspx?…”
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Development and validation of a prognostic prediction model for elderly gastric cancer patients based on oxidative stress biochemical markers by Xing-Qi Zhang, Ze-Ning Huang, Ju Wu, Chang-Yue Zheng, Xiao-Dong Liu, Ying-Qi Huang, Qi-Yue Chen, Ping Li, Jian-Wei Xie, Chao-Hui Zheng, Jian-Xian Lin, Yan-Bing Zhou, Chang-Ming Huang

“…Our findings emphasize the importance of oxidative stress in cancer prognosis and provide a pathway for improved management of GC. Trial registration Retrospectively registered at ClinicalTrials.gov (trial registration number: NCT06208046, date of registration: 2024–05-01).…”
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Assessing Sedation Depth with PSI in Elderly ERCP Patients: A Prospective Cohort Study by Huang L, Liu LL, Lu YD, Zhuang MY, Dou W, Liu H, Ji FH, Peng K

“…Our results showed a significant correlation between the PSI values and MOAA/S scores and suggested a PSI value of 50 with a range of 48 to 52 for maintaining adequate sedation.Trial Registration: Chinese Clinical Trial Registry (ChiCTR2400079859).Keywords: endoscopic retrograde cholangiopancreatography, depth of sedation, elderly patients, Modified Observer’s Assessment of Alertness/Sedation, patient state index…”
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