Single-cell RNA sequencing reveals the dysfunctional characteristics of PBMCs in patients with type 2 diabetes mellitus by Jindong Zhao, Jindong Zhao, Jindong Zhao, Zhaohui Fang, Zhaohui Fang, Zhaohui Fang

“…Exploring T2DM biomarkers via single-cell RNA sequencing (scRNA-seq) could provide new insights into the underlying molecular mechanisms.MethodsThe clinical trial registration number is ChiCTR2100049613. In this study, we included three healthy participants and three T2DM patients. …”
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Physical Inactivation of Monodon Baculovirus (Mbv), a Pathogenic Virus of Tiger Prawn (Penaeus Monodon Fab.) by M. Alifuddin

“…This study was conducted by transmission trial and physical inactivation of virus MBV.  Preparation of inoculum followed Momoyama and Sano (1988); shrimp test were infected by water borne infection.  …”
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Low-Frequency Repetitive Transcranial Magnetic Stimulation for Stroke-Induced Upper Limb Motor Deficit: A Meta-Analysis by Lan Zhang, Guoqiang Xing, Shiquan Shuai, Zhiwei Guo, Huaping Chen, Morgan A. McClure, Xiaojuan Chen, Qiwen Mu

“…Future studies should determine if LF-rTMS alone or in conjunction with practice/training would be more effective. Clinical Trial Registration Information. This trial is registered with unique identifier CRD42016042181.…”
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Use of Pre- and Intensified Postprocedural Physiotherapy in Patients with Symptomatic Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement Study (the 4P-TAVR Study) by M. Weber, U. Klein, A. Weigert, W. Schiller, V. Bayley-Ezziddin, D. C. Wirtz, A. Welz, N. Werner, E. Grube, G. Nickenig, J.-M. Sinning, A. Ghanem

“…Longer follow-up, a multicenter design, and a higher number of subjects are needed to confirm these preliminary results. This trial is registered with DRKS00017239.…”
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Proteasome inhibition enhances oncolytic reovirus therapy in multiple myeloma independently of its direct cytotoxic effects by Ada Alice Dona, Theophilus Tandoh, Lokesh Nigam, Mahmoud Singer, Enrico Caserta, Mariam Murtadha, Yinghui Zhu, Milad Moloudizargari, Preeti Sharma, Ottavio Napolitano, Janet Winchester, Arnab Chowdhury, Alex Pozhitkov, James F. Sanchez, Hawa Vahed, Guido Marcucci, Matt Coffey, Gerard Nuovo, Douglas W. Sborov, Flavia Pichiorri, Craig C Hofmeister

“…T-cell receptor (TCR) sequencing was also conducted both in immune competent MM mice and in patients enrolled in a phase 1b trial per a standard 3 + 3 dose escalation schedule. …”
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Accommodating inappropriate language: how students react to the translation of inappropriate language in the classroom by Tracey Simpson

“…However, the use of words considered as taboo is problematic for non-native speakers; they are consequently reduced to a system of trial and error at their own peril. We may then ask ourselves how taboo words are perceived by students and what place they have in the classroom. …”
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Unmasking Currents: Thinking Power and War with Foucault and the Black Panthers by Jason Demers

“…In the context of such a war, assassination, trial, detention, and other strategic political operations are masked as juridical procedures.…”
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The Canadian Multicentre MAC Treatment Study by Stephen D Shafran, The Canadian HIV Trials Network

“…A Canadian Multicentre MAC Treatment Trial was proposed in 1990 and finally implemented in late 1992 via the Canadian HIV Trials Network with the assistance of 6 pharmaceutical companies. …”
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Antibiotic Prophylaxis in Transarterial Therapy of Hepatocellular Carcinoma: A Meta-Analysis by Jun Wang, Xiao Dong He, You Cheng Zhang

“…Accordingly, this meta-analysis examined clinical trial evidence regarding the effects of prophylactic antibiotic therapy versus no prophylactic treatment with respect to infectious complications in patients undergoing transarterial therapy for HCC.…”
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An Unusual Case of Systemic Lupus Erythematosus and Hemophagocytic Syndrome by Saika Sharmeen, Nazia Hussain

“…He simultaneously met the Systemic Lupus International Collaborating Clinics (SLICC) criteria for the diagnosis of systemic lupus erythematosus (SLE) and the diagnostic criteria of HS as described in the hemophagocytic lymphohistiocytosis (HLH) 2004 trial. The bone marrow on autopsy showed the presence of abundant hemosiderophages with focal hemophagocytosis. …”
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Cost Analysis of Monitoring Asthma Treatment using Sputum Cell Counts by Liesel D’silva, Amiram Gafni, Lehana Thabane, Lata Jayaram, Pat Hussack, Frederick E Hargreave, Parameswaran Nair

“…BACKGROUND: In a four-centre trial, the use of sputum cell counts (sputum strategy [SS]) to guide treatment had resulted in fewer and less severe exacerbations without the need for a higher corticosteroid dose, compared with the use of symptoms and spirometry (clinical strategy [CS]).…”
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Air Turbines for Wave Energy Conversion by Manabu Takao, Toshiaki Setoguchi

“…The overall performances of the turbines under irregular wave conditions, which typically occur in the sea, have been compared by numerical simulation and sea trial. As a result, under irregular wave conditions it is found that the running and starting characteristics of the impulse type turbines could be superior to those of the Wells turbine. …”
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Use of Gibberellic Acid to Improve Health and Productivity of HLB-Affected ‘Valencia’ Trees by Tripti Vashisth

“…Recently, a multiyear field trial conducted on ‘Valencia’ has shown that GA applied monthly from September to January can improve yield of HLB-affected trees on average by 30% compared to untreated trees. …”
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Analysis of the Stability of Reinforced Plastic Waste Treated Clay as Embankment Fill on Soft Soils by Shelema Amena

“…The factor of safety of each trial is taken to check the stability of the modeled embankments. …”
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Stability Analysis of the Bat Algorithm Described as a Stochastic Discrete-Time State-Space System by Janusz Piotr Paplinski

“…The tuning rules are very general and need experiments during a trial and error method. The equations describing the bat algorithm have the form of difference equations, and the algorithm can be treated as a stochastic discrete-time system. …”
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Simulating Chemistry with Fermionic Optical Superlattices by Fotios Gkritsis, Daniel Dux, Jin Zhang, Naman Jain, Christian Gogolin, Philipp M. Preiss

“…Using native Hubbard dynamics, trial ground states of molecular Hamiltonians can be prepared and their molecular energies measured in the lattice. …”
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The transition from the Pre-Pottery to the early Pottery Neolithic period at the site of Uğurlu on the Island of Gökçeada, NE Aegean by Nejat Yücel

“…Although pottery production, which emerged without trial and error, indicates pre-existing knowledge, the first pottery was entirely of local production. …”
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Adult acute megakaryoblastic leukemia with persistent diarrhea and extreme thrombocytosis: A very unusual case by Nevin Alayvaz Aslan, Gülsün Gülten

“…Patients with megakaryoblastic leukemia respond poorly to standard induction regimens and they should be advised to participate in a clinical trial.…”
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Reduction of Free Edge Peeling Stress of Laminated Composites Using Active Piezoelectric Layers by Bin Huang, Heung Soo Kim

“…The approach is the extended Kantorovich method which is an iterative method. Multiterms of trial function are employed and governing equations are derived by taking the principle of complementary virtual work. …”
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Doppler Estimation Based on Frequency Average and Remodulation for Underwater Acoustic Communication by Chan-Ho Hwang, Ki-Man Kim, Seung-Yong Chun, Sang-Kook Lee

“…We conducted the simulation and sea trial to evaluate the performance of the proposed method. …”
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