Acute Kidney Injury, Mild Cognitive Impairment, and Dementia: A Cohort Study of Patients from SPRINT by Kristen L. Nowak, Anna Ostrow, Ester S. Oh, Zhiying You, Michel Chonchol

“…Setting & Participants: 8,148 older adults at high cardiovascular risk enrolled in the Systolic Blood Pressure Intervention Trial (SPRINT). Predictor: Adjudicated AKI as a time-varying predictor. …”
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Identifying Who Benefits the Most from a Community Health Worker-Led Multicomponent Intervention for Hypertension by Meng Pan, Andrea Beratarrechea, Rosana Poggio, Hua He, Chung-Shiuan Chen, Jing Chen, Vilma Irazola, Adolfo Rubinstein, Jiang He, Katherine T. Mills

“…This secondary analysis used data from HCPIA, a successful 18-month cluster-randomized trial in 18 health centers with 1,432 low-income hypertensive patients in Argentina. …”
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Classification of kinesiophobia in patients after cardiac surgery under extracorporeal circulation in China: latent profile and influencing factors analysis from a cross-sectional... by Qi Li, Rong Wang, Yanmei Gu, Tong Ren, Jing Jing Piao, Wenhui Xing, Yujing Liang

“…These findings provide a basis for implementing preventive interventions in cardiac rehabilitation.Trial registration number The research is registered with the Chinese Clinical Trial Registry (ChiCTR2200057895).…”
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Development and validation of the Multimorbidity Treatment Burden Questionnaire (MTBQ) by Daisy Gaunt, Chris Salisbury, Mei-See Man, Katherine Chaplin, Polly Duncan, Mairead Murphy

“…It is a useful research tool for assessing the impact of interventions on treatment burden.Trial registration number ISRCTN06180958.…”
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Attitudes and adherence to changes in nutrition and physical activity following surgery for prostate cancer: a qualitative study by Richard M Martin, Raj Persad, J Athene Lane, Ellie Shingler, Luke A Robles, Edward Rowe, Anthony Koupparis, Amit Bahl, Constance Shiridzinomwa, Lucy McGeagh

“…We aimed to explore these factors in men following prostatectomy for prostate cancer (PCa).Design, setting and participants A qualitative study using semistructured interviews with men, who made changes to their diet and/or PA as part of a factorial randomised controlled trial conducted at a single hospital in South West England. …”
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Safety and Efficacy of Hydroxypropyl Guar-Hyaluronic Acid Dual-Polymer Lubricating Eye Drops in Indian Subjects with Dry Eye: A Phase IV Study by Deborah Awisi-Gyau, Neha Kapur, Rajesh Parekh, Umesh Yeddula, Shreesha Kumar Kodavoor

“…Conclusions HPG-HA dual-polymer eye drop was safe and effective in relieving signs and symptoms of DED over 90 days in Indian subjects. Trial Registration Clinical Trial Registry India, CTRI/2022/03/041175.…”
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Safety and tolerability of intramuscular sotrovimab administered at different injection sites: results from the Phase 1 COSMIC study by Jennifer Moore, Alicia Aylott, Wen-Hung Chen, Jerzy Daniluk, Ian A. Hawes, Sergio Parra, Prosenjit Sarkar, Yasmin Sanchez-Pearson, Megan Turner, Amanda Peppercorn, Andrew Skingsley

“…To our knowledge, these are the first data to show that a >2 mL mAb injection into each deltoid muscle is well tolerated.Trial registration ClinicalTrials.gov identifier, NCT05280717…”
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A Small Increase in Serum Creatinine within 48 h of Hospital Admission Is an Independent Predictor of In-Hospital Adverse Outcomes in Patients with ST-Segment Elevation Myocardial... by Jiajia Zhu, Wenxian Liu, Jiang Li, Changsheng Ma, Dong Zhao

“…This effect is maintained in patients with normal Scr at hospitalization. Trial Registration. Clinical trial registration: URL: https://www.clinicaltrials.gov. …”
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Ezetimibe Improves Rosuvastatin Effects on Inflammation and Vascular Endothelial Function in Acute Coronary Syndrome Patients Undergoing PCI by Changqing Sun, Wuyang Zheng, Ling Liang, Zuheng Liu, Wenchao Sun, Rong Tang

“…Periprocedural therapy of ezetimibe improves rosuvastatin effects on proinflammatory responses and endothelial function associated with ACS patients undergoing PCI. This trial is registered with https://clinicaltrials.gov/ct2/show/ChiCTR-IPR-17012219 (Chinese Clinical Trial Registry, http://www.chictr.org.cn on 02/08/2017).…”
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“It's a good idea, but…”: a qualitative evaluation of the GoldiCare intervention in Norwegian home care services by Heike Fischer, Fredrik Klæboe Lohne, Fredrik Klæboe Lohne, Marius Steiro Fimland, Skender Elez Redzovic

“…Performed in the right way, such integration will also allow for more participatory input from those enacting such interventions. Trial registrationThis clinical trial was registered on 08/05/2022 under NCT05 487027.…”
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Percutaneous Closure Device Controlled INCRAFT Stentgraft Implantation Registry (PUCCINI) by T. Engelen, R. Hoogervorst, K. DeLoose, L. C. van Dijk, R. S. van Eps, R. B. van Tongeren, H. T. Veger, L. Maene, W. Stomp, O. R. Wikkeling, S. J. C. Klink, W. van den Eynde, J. J. Wever, H. van Overhagen

“…The feasibility and safety of the use of the INCRAFT AAA Stentgraft System and the ProGlide vascular closure system was assessed. Methods The PUCCINI trial prospectively enrolled patients undergoing elective repair of infrarenal AAA at 3 centres in the Netherlands and 3 centres in Belgium. …”
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Exploring the Variability in Acute Glycemic Responses to Exercise in Type 2 Diabetes by Tasuku Terada, Alanna Friesen, Baljot S. Chahal, Gordon J. Bell, Linda J. McCargar, Normand G. Boulé

“…Lower blood glucose can be achieved with moderate intensity exercise, but prolonging exercise duration and/or including brief bouts of intense exercise accentuate the reduction, which can further be magnified by performing exercise after meals and antihyperglycemic medication. This trial is registered with ClinicalTrial.gov NCT01144078.…”
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The Effects of Trenbolone Supplementation on The Extremity Bones in Running Rats by Ali Sarı, Sefa Lök

“…We believe that the results obtained from this trenbolone trial will provide important data to the studies that will be conducted on anabolic androgenic steroids.     …”
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IMRAS-Immunization with radiation-attenuated Plasmodium falciparum sporozoites by mosquito bite: Cellular immunity to sporozoites, CSP, AMA1, TRAP and CelTOS. by Martha Sedegah, Michael R Hollingdale, Harini Ganeshan, Maria Belmonte, Jun Huang, Arnel Belmonte, Sandra Inoue, Rachel Velasco, Bradley Hickey, Nimfa Teneza-Mora, Joanne Lumsden, Sharina Reyes, Jo Glenna Banania, Anatalio Reyes, Ivelese Guzman, Thomas L Richie, Judith E Epstein, Eileen Villasante

“…The correlation between fold-increases in responses and protection should be explored in other vaccine trials.<h4>Trial registration</h4>ClinicalTrials.gov NCT01994525.…”
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The Biopsychosocial Burden of Prostate Biopsy at the Time of Its Indication, Procedure, and Pathological Report by Walker W. Laranja, Brunno C. F. Sanches, Brunno R. I. Voris, João C. C. Alonso, Fabiano A. Simões, Ronald F. Rejowski, Leonardo O. Reis

“…To be considered in patients' counseling and care, the current study supports the hypothesis that the peak burden of prostate biopsy occurs at the time of its indication and might be higher for those experiencing rebiopsy, significantly impacting patients' psychosocial domains. Trial Approval. This trial is registered under number NCT03783741.…”
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Cohort profile: Outcome Monitoring After Cardiac Surgery (OMACS) – a prospective UK cohort study of cardiac surgery patients at the Bristol Heart Institute by Chris A Rogers, Gianni Angelini, Lucy Culliford, Rachel Brierley, Barnaby Reeves, Katherine Joyce, Terrie Walker-Smith, Rachel Maishman, Emma Hopkins, Penny Lambert, Helena Smartt

“…The data and samples will be available for sharing in a linked anonymised format.Trial registration number ISRCTN90204321 (date assigned: 21 January 2015).…”
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Outcomes and safety of mechanical thrombectomy, alteplase, and conventional medical care in the treatment of acute M2 segment middle cerebral artery occlusion: a comparative study by Eman M. Khedr, Ahmed Elbassiouny, Mahmoud Nageeb, Ahmed Aly, Khalid O. Mohamed, Nourelhoda A. Haridy

“…MT of M2 is feasible and effective, with a lower hemorrhage rate than rTPA and CMT. Trial registration: This study was prospectively registered in the clinical trial with ClinicalTrials.gov ID (NCT05091320). …”
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Timed Bromocriptine-QR Therapy Reduces Progression of Cardiovascular Disease and Dysglycemia in Subjects with Well-Controlled Type 2 Diabetes Mellitus by Bindu Chamarthi, J. Michael Gaziano, Lawrence Blonde, Aaron Vinik, Richard E. Scranton, Michael Ezrokhi, Dean Rutty, Anthony H. Cincotta

“…Methods. 1834 subjects (1219 bromocriptine-QR; 615 placebo) with baseline HbA1c ≤7.0% derived from the Cycloset Safety Trial (this trial is registered with ClinicalTrials.gov Identifier: NCT00377676), a 12-month, randomized, multicenter, placebo-controlled, double-blind study in T2DM, were evaluated. …”
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Telemedicine in home enteral nutrition: a structured survey exploring acceptability, preferences and experiences among patients by Ya Ma, Xuemei Li, Qian You, Wen Hu, Zhiyong Rao, Yanru Deng, Yiyao Zhang, Lei Shi

“…We should optimize and promote existing video call function of this platform to meet the demands of face-to-face communication. Trial registration The study was registered in the Chinese Clinical Trial Registry (clinical registration number: ChiCTR2100053762, registration date: 2021–11-29).…”
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Pain Reduction in Patellofemoral Knee Patients During 3-Month Intervention with Biomechanical and Sensorimotor Foot Orthoses: A Randomized Controlled Clinical Study by Steven Simon, Andreas Heine, Jonas Dully, Carlo Dindorf, Oliver Ludwig, Michael Fröhlich, Stephan Becker

“…<b>Conclusions:</b> The findings indicate that both treatment approaches effectively alleviated perceived knee pain in the PFP sample with foot deformity, with neither approach demonstrating superior efficacy. This trial was registered in the WHO International Clinical Trials Registry Platform (ICTRP) and German Clinical Trials Register (DRKS00035082).…”
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