Additive Effects of Exercise and Vitamin D Supplementation (with and without Calcium) on Bone Mineral Density in Older Adults: A Systematic Review and Meta-Analysis by Cecilie Fischer, Franz Jakob, Matthias Kohl, Stephanie Kast, Simon Von Stengel, Katharina Kerschan-Schindl, Uwe Lange, Friederike Thomasius, Stefan Peters, Michael Uder, Wolfgang Kemmler

“…Heterogeneity between the trial results was moderate-substantial for LS (I2 = 0%) and moderate for hip-BMD (I2 = 35%). …”
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A Randomized, Double-Masked, Active-Controlled, Crossover Phase III Equivalence Study of Generic Dorzolamide 2% versus Innovator Trusopt® Eye Drop Solution in Subjects with Open-An... by Katharina Bell, Christina Korb, Christina Butsch, Bert Constantin Giers, Anna Beck, Alicja Strzalkowska, Christian Ruckes, Ulrike Klingberg, Norbert Pfeiffer, Katrin Lorenz

“…This study showed the equivalence of the tested generic dorzolamide 2% eye drops solution to the reference product Trusopt® eye drops solution. Trial Registration. This trial is registered with (ClinicalTrials.gov (identifier: NCT00878917) on April 9, 2009).…”
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Initial use of supplementary oxygen for trauma patients: a systematic review by Trine Grodum Eskesen, Josefine Stokholm Baekgaard, Jacob Steinmetz, Lars S Rasmussen

“…One interventional trial of intubated trauma patients was included. 68 trauma patients were randomised to receive an FiO2 of 0.80 (intervention group) or 0.50 (control group) during mechanical ventilation (first 6 hours). …”
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Bupivacaine–fentanyl isobaric spinal anesthesia reduces the risk of ICU admission in elderly patients undergoing lower limb orthopedic surgery by Wenxun Liu, Shuzhen Bao, Jiaxin Chen, Yan Li, Yinghua Gu, Qingshan Ye, Kerong Hai

“…Conclusions Bupivacaine–fentanyl isobaric spinal anesthesia significantly reduced the risk of ICU admission and unplanned intubation, and provided better intraoperative hemodynamics in elderly patients undergoing lower limb orthopedic surgery. Trial registration: This study has been registered in the Chinese Clinical Trial Registry (ChiCTR2000033411).…”
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Sedative Effect of Nasal Midazolam-Ketamine at Different Doses on 3-6-year-old Uncooperative Dental Patients by Masoud Fallahinejad Ghajari, Ghassem Ansari, Mostafa Mohaveri, Ahmad Eghbali Zarch, Sajjad Razavi

“…Objectives: This randomized clinical trial compares higher and lower-dose intranasal ketamine/midazolam cocktails in pediatric dentistry.  …”
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Health care provider's perceived factors for the increased practice of caesarean delivery in North West Amhara referral hospitals, Ethiopia, 2022: a qualitative study by Mulat Ayele, Marta Berta, Amare Zewudie, Eyob Shitie Lake, Gizachew Yilak, Befkad Derese Tilahun, Mastewal Belayneh Aklil

“…Encouraging greater emphasis on trial of labor, instrumental delivery, and performing caesarean deliveries only when there are definitive obstetric indications, rather than for social or maternal requests, can contribute to reducing the prevalence of caesarean delivery rates.…”
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Phase 1 study of novel anti-platelet agent to overcome pharmacogenomic limitations of clopidogrel by Anil Pareek, Nitin Chandurkar, Vivek Raut, Kumar Naidu

“…It can be further developed in clinical studies for the unmet medical needs in management of CVDs and overcome the pharmacogenomic limitations of Clopidogrel.Trial registration number Clinical Trial Registry-India URL: http://ctri.nic.in. …”
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The Effect of Submucosal Injection of Plasma-Rich Platelets on Blood Inflammatory Markers for Patients with Bimaxillary Protrusion Undergoing Orthodontic Treatment by Trefa Mohammed Ali Mahmood, Omar Fawzi Chawshli

“…Thus, further investigation is recommended to follow up the patient for a longer period of time and on a larger sample. This trial is registered with U1111-1221-8829 by Sri Lanka Clinical Trial Registry, SLCTR/2018/040, and No. 64 on 6th August 2018 at the local clinical studies database, College of Dentistry.…”
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Beehive Fireworks Festival Effect on the Nearby Atmospheric PM2.5 Level by Chih-Chung Lin, Jen-Hsiung Tsai, Yi-Chin Hsieh, Shui-Jen Chen

“…The atmospheric PM2.5 level in major activity areas was significantly higher from the background level in the trial and festival periods, and even after the activity. …”
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Socket Preservation Using Platelet-Rich Fibrin and Free Gingival Grafts by Haya Hesham Abdel-Latif Afifi, Shaimaa Saieed Nasr, Munerah Saleh BinShabaib, Shatha Subhi Alharthi, Mona Shoeib

“…ABSTRACT: Objective: The present randomised controlled trial is based on the null hypothesis that there is no difference in crestal bone levels (CBLs) following socket preservation (SP) using platelet-rich fibrin (PRF) and free gingival graft (FGG). …”
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The Safety and Tolerability of 5-Aminolevulinic Acid Phosphate with Sodium Ferrous Citrate in Patients with Type 2 Diabetes Mellitus in Bahrain by Feryal Al-Saber, Waleed Aldosari, Mariam Alselaiti, Hesham Khalfan, Ahmed Kaladari, Ghulam Khan, George Harb, Riyadh Rehani, Sizuka Kudo, Aya Koda, Tohru Tanaka, Motowo Nakajima, Abdulla Darwish

“…Overall, the current results support that use of 5-ALA-SFC up to 200 mg per day taken as 2 divided doses is safe in patients taking concomitant oral antidiabetic medications and may offer benefits in the diabetic population. This trial is registered with ClinicalTrials.gov NCT02481141.…”
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Human–Robot Interactions: A Pilot Study of Psychoaffective and Cognitive Factors to Boost the Acceptance and Usability of Assistive Wearable Devices by Margherita Bertuccelli, Stefano Tortora, Edoardo Trombin, Liliana Negri, Patrizia Bisiacchi, Emanuele Menegatti, Alessandra Del Felice

“…., 10 m path walking for 10 trials). Pre-trial anxiety levels were higher than post-trial ones (<i>p</i> < 0.01). …”
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The efficacy of a low-dose combination of febuxostat and benzbromarone versus each drug used alone for the treatment of gout by Caiyu Zheng, Caiyu Zheng, Qingwen Tong, Qingwen Tong, Zhijun Zhang, Chunmei Lin, Zhiyi Wang, Dongshu Kang, Yanmei Lin, Jianqing Tian

“…ObjectiveThe study focuses on comparing the efficacy of a low-dose combination of febuxostat and benzbromarone versus each drug used alone for the treatment of gout.MethodsA prospective, randomized, open-labeled trial of men with gout and renal uric acid underexcretion was conducted. …”
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Enhancing stone expulsion: The efficacy of combined medical therapy with tamsulosin and dexamethasone in renal colic patients by Reza Kazemi, Mohammad Shahrashoub, Amir Javid, Narjes Saberi, Pouria Ghasemi, Saina Paymannejad

“…Among them, 105 patients were eligible and included in the trial and were randomly assigned into the intervention group (n = 52) and control group (n = 53). …”
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Intensive Farmaco- Surveillance of Interferon Alpha 2b Recombinant in Multiple Sclerosis. by Leslie Pérez Ruiz, Ana María Ramos Cedeño, José Cabrera Gómez, Nancy Echazábal Santana, Hailen Bobillo López

“…</span><strong><span style="font-weight: bold; font-family: Tahoma;">Method:</span></strong><span style="font-family: Tahoma;"> During the period between 1996 and 2006, 70 clinical histories and data collection notebooks of patients included in the randomized double blind national clinical trial phase IV were revised. This trial was developed in the Clinic of Multiple Sclerosis of the Hospital "Dr. …”
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A systematic review of the impact of artificial intelligence on educational outcomes in health professions education by Eva Feigerlova, Hind Hani, Ellie Hothersall-Davies

“…Clinical Trial number: not applicable.…”
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Role of Terlipressin in Cirrhotic Patients with Ascites and without Hepatorenal Syndrome: A Systematic Review of Current Evidence by Zhaohui Bai, Yang An, Xiaozhong Guo, Rolf Teschke, Nahum Méndez-Sánchez, Hongyu Li, Xingshun Qi

“…In 3 studies (1 randomized controlled trial and 2 single-arm studies without controls) involving 32 patients who received terlipressin for nonrefractory ascites, terlipressin improved hemodynamics by decreasing the heart rate and cardiac output and increasing the mean arterial pressure and systemic vascular resistance. …”
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Impact of social media on triggering nonsuicidal self-injury in adolescents: a comparative ambulatory assessment study by Andreas Goreis, Dorothy Chang, Diana Klinger, Heidi-Elisabeth Zesch, Bettina Pfeffer, Sofia-Marie Oehlke, Ulrich W. Ebner-Priemer, Laurence Claes, Paul L. Plener, Oswald D. Kothgassner

“…These results underscore the need for targeted interventions addressing online interactions to mitigate NSSI behaviors and improve adolescent mental health. Trial registration This study has been registered at the German Clinical Trials Register (ID: DRKS00025905, https://drks.de/search/en/trial/DRKS00025905 ).…”
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Feasibility and acceptability of a virtual learning module for navigating angry conversations in clinical encounters by Valerie Shilling, Rachel Starkings, Lesley Fallowfield

“…There should be a consideration as to how to incorporate VL, with a mix of face-to-face practice for added realism. Trial Registration Clinical trial number not applicable.…”
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Association of Serum Adiponectin with Intima Media Thickness of Dorsalis Pedis Artery and Macroangiopathy in Type 2 Diabetes by Tao Chen, Mei Tu, Lihua Huang, Youping Zheng

“…Decrease of adiponectin as an independent risk factor for both macroangiopathy and D-IMT among Chinese patients with T2DM suggests that adiponectin might have clinical utility in the prediction of diabetic macroangiopathy. This clinical trial is registered in the “Chinese Clinical Trial Registry.” …”
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