Understanding recruitment to a perioperative randomised controlled trial: protocol for a mixed-methods substudy nested within a feasibility trial of octreotide infusion during liver transplantation by Duncan Wagstaff, S Ramani Moonesinghe, Jez Fabes, Michael Spiro, Edgar Brodkin, Ee-Neng Loh, Vivienne Hannon

“…Introduction Recruitment to perioperative randomised controlled trials is known to be challenging. Qualitative methods offer insight into barriers and enablers to participation. …”
Get full text

Emulation of ARISTOTLE and ROCKET AF trials in real-world atrial fibrillation patients results in similar efficacy and safety as original landmark trials: insights from the GARFIELD-AF registry by Ralf E Harskamp, Karen Pieper, A John Camm, Ajay K Kakkar, Jelle C L Himmelreich, Saverio Virdone, Jean-Pierre Bassand, Frank Misselwitz, Freek W A Verheugt, Frank Cools, Harry Gibbs, Antônio C Pereira-Barretto

“…Aims This study aimed to determine the robustness, reproducibility and representativeness of the landmark Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (AF) (ARISTOTLE) and Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in AF (ROCKET AF) randomised trials through replication in an observational AF patient registry.Methods and results Patients from the Global Anticoagulant Registry in the FIELD (GARFIELD)-AF registry treated with apixaban, rivaroxaban or vitamin K antagonist (VKA) were assessed for eligibility for the ARISTOTLE and ROCKET AF trials. …”
Get full text

Classification of environments based on correlations of yield in spring bread wheat by S. B. Lepekhov

Subjects: “…multi-environment trial…”
Get full text

Brief Mindfulness-Based Cognitive Therapy in Women With Myocardial Infarction by Tanya M. Spruill, PhD, Chorong Park, PhD, RN, Jolaade Kalinowski, EdD, Milla E. Arabadjian, PhD, RN, Yuhe Xia, MSc, Amanda J. Shallcross, ND, MPH, Pallavi Visvanathan, PhD, Nathaniel R. Smilowitz, MD, MS, Anaïs Hausvater, MD, Sripal Bangalore, MD, MHA, Hua Zhong, PhD, Ki Park, MD, Puja K. Mehta, MD, Dwithiya K. Thomas, MD, Jeffrey Trost, MD, Kevin R. Bainey, MD, Bobak Heydari, MD, Janet Wei, MD, Victoria Vaughan Dickson, PhD, RN, Gbenga Ogedegbe, MD, MPH, Jeffrey S. Berger, MD, MS, Judith S. Hochman, MD, Harmony R. Reynolds, MD

Subjects: Get full text

Targeting Fibrosis: From Molecular Mechanisms to Advanced Therapies by Xingpeng Di, Ya Li, Jingwen Wei, Tianyue Li, Banghua Liao

Subjects: “…clinical trial…”
Get full text

Osilodrostat treatment in patients with Cushing’s disease of Asian or non-Asian origin: a pooled analysis of two Phase III randomized trials (LINC 3 and LINC 4) by Akira Shimatsu, Beverly MK Biller, Maria Fleseriu, Rosario Pivonello, Eun Jig Lee, Rattana Leelawattana, Jung Hee Kim, Rama Walia, Yerong Yu, Zhihong Liao, Andrea Piacentini, Alberto M Pedroncelli, Peter J Snyder

Subjects: Get full text

The effect of Ocimum basilicum on the prevention of postpartum depression symptoms and sleep quality: A triple-blind randomized controlled clinical trial by Monireh Abdi, Elham Rezaei, Mojgan Mirghafourvand, Fatemeh Ebrahimi, Laleh Payahoo, Alireza Shafiei-Kandjani, Solmaz Ghanbari-Homaie

Subjects: Get full text

Feasibility pilot of a novel coaching intervention to optimize cannabis use for chronic pain management among Veterans by Kevin F. Boehnke, Gabrielle Bowyer, Jenna McAfee, Tristin Smith, Catherine Klida, Vivian Kurtz, Evangelos Litinas, Poonam Purohit, Anne Arewasikporn, Dana Horowitz, Laura Thomas, Jennifer Eckersley, Mia Railing, David A. Williams, Daniel J. Clauw, Kelley M. Kidwell, Amy S. B. Bohnert, Rachel S. Bergmans

Subjects: Get full text

Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity by Jaeseong Oh, Sojeong Yi, Namyi Gu, Dongseong Shin, Kyung-Sang Yu, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang

Subjects: “…clinical trial…”
Get full text

Discrepancies in reported results between trial registries and journal articles for AI clinical researchResearch in context by Zixuan He, Lan Yang, Xiaofan Li, Jian Du

Subjects: “…Clinical trial…”
Get full text

Reporting and representation of participant race and ethnicity in phase III clinical trials for solid tumors by Tianyi Wang, Dinorah J Villanueva, Ambily Banerjee, Dina Gifkins

Subjects: Get full text

Advancements in Managing Anthracycline-Induced Cardiotoxicity: Insights from Interventional Clinical Trials by Zhao M, Zhang X, Zhou D, Song J

Subjects: Get full text

Chapter 12. NE-1014 Regional Project Potato Variety Trial, 2006 by Chad M. Hutchinson, Doug Gergela

Get full text

Therapeutic potential of cannabinoids in neurological conditions: a systematic review of clinical trials by Alqassem Y. Hakami, Alqassem Y. Hakami, Fahad S. Alshehri

Subjects: Get full text

Pre-trial investigation in the de-occupied territories: normative regulation and prospects for implementation by T. H. Fomina

Subjects: Get full text

Preemptive Treatment of Nausea and Vomiting of Pregnancy: Results of a Randomized Controlled Trial by Caroline Maltepe, Gideon Koren

“…Prospective, randomized controlled trial. Results. Preemptive therapy conferred a significant reduction in HG as compared to the previous pregnancy (P=0.047). …”
Get full text

Home-Based Intervention Tool for Cardiac Telerehabilitation: Protocol for a Controlled Trial by Francesca Mastorci, Maria Francesca Lodovica Lazzeri, Lamia Ait-Ali, Paolo Marcheschi, Paola Quadrelli, Massimiliano Mariani, Rafik Margaryan, Wanda Pennè, Marco Savino, Giuseppe Prencipe, Alina Sirbu, Paolo Ferragina, Corrado Priami, Alessandro Tommasi, Cesare Zavattari, Pierluigi Festa, Stefano Dalmiani, Alessandro Pingitore

Get full text

A network meta-analysis of therapies for hyperphosphatemia in CKD based on randomized trials by Congyang Zheng, Jia Liu, Tao Wang, Haiyang Hu, Yuanyuan Chen

“…All randomized controlled trials on hyperphosphatemia published from January 2013 to November 2023 were searched from CNKI, VIP database, Wanfang database, PubMed, Scopus, and Cochrane databases. …”
Get full text

Chapter 3. White-Skinned Fresh Market Potato Variety Trial, 2006 by Chad M. Hutchinson, Doug Gergela

Get full text

CLINICAL TRIAL ASSESSING THE PREVALENCE OF ORAL COMPLICATION IN A DENTURE WEARERS POPULATION by Cosmin Bida, Doriana Agop-Forna, Dana Gabriela Budala, Norina Forna

Get full text