EVALUATING THE IMPACT OF MASS TOURISM ON THE HOSPITALITY INDUSTRY AND TOURISM DESTINATION DEVELOPMENT OF CROSS RIVER STATE, NIGERIA by Nnana Okoi OFEM, Chinasa UTTAH, Ndem Samuel ETIM, Queen Olubukola AYENI, Josephat Owan EMEKA, Agnes Awoli EWURU, Maxwell-Borjor Achuk EBA, Eja Iwara EJA, Jeremiah ABANBESHIE, Daniel Daniel JAMES, Ayuk Awunghe ACHU, Michael Takim OTU, Fidelis Ngaji AKWAJI, Etta Oyen ETTA

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Design of localization course by Rimgaudas Laucius, Valentina Dagienė

“…However, teaching of software localization is not a part of translators’ studies. All localizers are still volunteers. …”
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Live or Die: Choice Mechanisms in Stressed Cells by Francesco Cecconi, Laura Soucek, Dennis D. Taub, Elio Ziparo

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The Need for Inducing Tolerance in Vascularized Composite Allotransplantation by Kadiyala V. Ravindra, Hong Xu, Larry D. Bozulic, David D. Song, Suzanne T. Ildstad

“…In order to optimize VCA outcomes, translational studies are needed to develop less toxic immunosuppression and possibly achieve donor-specific tolerance. …”
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La violence par partenaire intime : enjeux traductologiques et politiques des catégorisations de la violence by Samantha Saïdi

“…This article proposes a social and political translation study that focuses on the circulation and methods of circulation (translation, re-use, re-analysis, ...) of the categories of violence adopted by the multidisciplinary field studying intimate partner violence (IPV). …”
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Spontaneous, naturally occurring cancers in non-human primates as a translational model for cancer immunotherapy by Maurizio Ceppi, Bruno Gomes, Simon Deycmar, Jehad Charo, J Mark Cline

“…The complexity of cancer immunotherapy (CIT) demands reliable preclinical models to successfully translate study findings to the clinics. Non-human primates (NHPs; here referring to rhesus and cynomolgus macaques) share broad similarities with humans including physiology, genetic homology, and importantly also immune cell populations, immune regulatory mechanisms, and protein targets for CIT. …”
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Ventral Prostate Fibrosis in the Akita Mouse Is Associated with Macrophage and Fibrocyte Infiltration by Sanghee Lee, Guang Yang, William Mulligan, Jerry Gipp, Wade Bushman

“…These observations support the inference that diabetes elicits monocyte/macrophage infiltration and collagen accumulation in the prostate and suggest that further study of Akita mice may inform translational studies of diabetes in the genesis prostatic inflammation, prostatic fibrosis, and LUTS.…”
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The Review and Analysis of the Book: "Seasons of the Transfiguration and Al-Tarib" from Experience to Translation by Reza Nazemian

“…Considering that books on translation theory have a relatively long history and even a few books have been published in Arabic, the book "The Fosoolfi al-tarjomah va al- tarib" was expected from Mohammad al-Batal which was published in 2007 to deepen the field of translational studies, but a glance at the book's list of sources suggests that the author has an extensive research effort. …”
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A conformational change of C-reactive protein drives neutrophil extracellular trap formation in inflammation by Ebru Karasu, Rebecca Halbgebauer, Lena Schütte, Johannes Greven, Felix M. Bläsius, Johannes Zeller, Oscar Winninger, David Braig, David Alexander Christian Messerer, Bettina Berger, Hendrik Feuerstein, Anke Schultze, Karlheinz Peter, Uwe Knippschild, Klemens Horst, Frank Hildebrand, Steffen U. Eisenhardt, Markus Huber-Lang

“…Results In a multi-translational study of systemic inflammation, we found a time- and inflammation-dependent pCRP dissociation into mCRP. …”
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Comparative transcriptomic rhythms in the mouse and human prefrontal cortex by Jennifer N. Burns, Jennifer N. Burns, Aaron K. Jenkins, Xiangning Xue, Kaitlyn A. Petersen, Kaitlyn A. Petersen, Kyle D. Ketchesin, Kyle D. Ketchesin, Megan S. Perez, Megan S. Perez, Chelsea A. Vadnie, Madeline R. Scott, Madeline R. Scott, Marianne L. Seney, Marianne L. Seney, George C. Tseng, Colleen A. McClung, Colleen A. McClung

“…However, investigation into the potential circadian mechanisms underlying these diseases in animal models must contend with the fact that the human PFC is highly evolved and specialized relative to that of rodents.MethodsHere, we use RNA sequencing to lay the groundwork for translational studies of molecular rhythms through a sex-specific, cross species comparison of transcriptomic rhythms between the mouse medial PFC (mPFC) and two subregions of the human PFC, the anterior cingulate cortex (ACC) and the dorsolateral PFC (DLPFC).ResultsWe find that while circadian rhythm signaling is conserved across species and subregions, there is a phase shift in the expression of core clock genes between the mouse mPFC and human PFC subregions that differs by sex. …”
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IONPs-induced neurotoxicity via cascade of neuro-oxidative stress, parthanatos-mediated cell death, neuro-inflammation and neurodegenerative changes: Ameliorating effect of rosemar... by Arwa A. Elsheikh, Noha Ali Abd-Almotaleb, Mona Mostafa Ahmed, Eman El-Sayed Khayal

“…Consequently, the current data provide evidence that RO supplementation during IONP administration holds promise to minimize potential health risks, which should be corroborated by translational studies.…”
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Expression of Leptin Receptor and Effects of Leptin on Papillary Thyroid Carcinoma Cells by Marilena Celano, Valentina Maggisano, Saverio Massimo Lepore, Marialuisa Sponziello, Valeria Pecce, Antonella Verrienti, Cosimo Durante, Marianna Maranghi, Piernatale Lucia, Stefania Bulotta, Giuseppe Damante, Diego Russo

“…Leptin receptor (OB-R) expression has also been documented in papillary thyroid cancer (PTC). Aim. In this translational study, we analyzed in vitro the effects of leptin on the growth and migration of thyroid cancer cells (TPC-1 and K1), the molecular mechanisms underlying leptin’s action, and the influence of prolonged leptin exposure on cell response to a protein kinase inhibitor lenvatinib. …”
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Pancreatic resection with perioperative drug repurposing of propranolol and etodolac: trial protocol of the phase-II randomised placebo controlled PROSPER trial by Phillip Knebel, Thilo Hackert, Markus W Büchler, Ilse Rooman, Markus K Diener, Felix J Hüttner, André L Mihaljevic, Oliver Strobel, Gauthier Bouche, Johannes Hüsing

“…The clinical trial is accompanied by a translational study investigating the mechanisms of action of the combined therapy on a molecular basis.Ethics and dissemination The PROSPER-trial has been approved by the German Federal Institute for Drugs and Medical Devices (reference number 4042875) and the Ethics Committee of the Medical Faculty of the University of Heidelberg (reference number AFmo-385/2018). …”
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How is depth of anaesthesia assessed in experimental pigs? A scoping review. by Alessandro Mirra, Ekaterina Gamez Maidanskaia, Luís Pedro Carmo, Olivier Levionnois, Claudia Spadavecchia

“…<h4>Background</h4>Despite the large number of pigs involved in translational studies, no gold standard depth of anaesthesia indicators are available. …”
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Cross-Culturally Adapted Versions of Patient Reported Outcome Measures for the Lower Extremity by Yongni Zhang, Jiayi Ren, Yaning Zang, Wenhao Guo, Ashley Disantis, Robroy L Martin

“… # Study design Literature Review # Methods PubMed, Embase, Medline, Cochrane, CINAHL, SPORTDisucs and Scopus were searched for cross-culturally adapted translated studies through May 2022. The search strategy included the names of the 20 recommended PROMs from previous umbrella review along with the following terms: reliability, validity, responsiveness, psychometric properties and cross-cultural adaptation. …”
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Electrophysiological properties of vestibular hair cells isolated from human crista by Nesrien Mohamed, Mohammad Al-Amin, Frances L. Meredith, Olivia Kalmanson, Anna Dondzillo, Stephen Cass, Samuel Gubbels, Katherine J. Rennie

“…Rapid access to surgically obtained adult human vestibular neuroepithelia allows translational studies crucial for improved understanding of human peripheral vestibular function.…”
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Spatial associations of Hansen's disease and schistosomiasis in endemic regions of Minas Gerais, Brazil. by Jessica L Stephens, Lucia A O Fraga, José A Ferreira, Laura De Mondesert, Uriel Kitron, Julie A Clennon, Jessica K Fairley

“…Not only did we provide an effective approach to study the epidemiology of two endemic neglected tropical diseases with geographic spatial analyses, we highlight the need for further clinical and translational studies to study the potential epidemiologic associations uncovered.…”
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Early assessment of IL8 and PD1+ Treg predicts response and guides treatment monitoring in cemiplimab-treated cutaneous squamous cell carcinoma by Teresa Troiani, Fabiana Napolitano, Luigi Formisano, Roberto Bianco, Daniela Russo, Daniela Esposito, Giuseppe Ercolano, Angela Ianaro, Alberto Servetto, Daniela Claudia Maresca, Marcella Scala, Annarita Amato, Stefania Belli, Claudia Maria Ascione, Angela Vallefuoco, Giovanna Attanasio, Fabio Somma, Silvia Varricchio, Massimo Mascolo, Claudia Costa, Alessia Villani, Massimiliano Scalvenzi, Gianfranco Orlandino

“…However, reliable biomarkers for patient selection are still lacking.Experimental design In this translational study, clinical annotations, tissue and liquid biopsies were acquired to investigate the association between sustained objective responses and transcriptional profiles, immune cell dynamics in tumor tissue and peripheral blood samples, as well as circulating cytokine levels.Results First, we investigated the baseline characteristics of the immune landscape of cSCC biopsies. …”
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A remarkable and durable response to tislelizumab treatment of an anaplastic thyroid carcinoma without targetable genomic alterations: a case report by Jingjing Chai, Jiaqi Lv, Jian Xiong, Xiuwen Chen, Senyuan Luo, Zhiguo Luo, Zhiguo Luo, Ming Luo

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Subcytotoxic transepidermal delivery using low intensity cold atmospheric plasma by Ga Ram Ahn, Hyung-Joon Park, Yu Jin Kim, Min Gyo Song, Hye Sung Han, Woo Geon Lee, Hyuck Ki Hong, Kwang Ho Yoo, Joon Seok, Kyu Back Lee, Beom Joon Kim

“…Under our study conditions, LICAP treatment seems to be a novel approach to facilitate TED with low safety concerns in vitro. Further translational studies are needed for clinical evaluation.…”
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