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12541
CD133+PD-L1+ cancer cells confer resistance to adoptively transferred engineered macrophage-based therapy in melanoma
Published 2025-01-01“…Compared to the CD133-PD-L1- cancer cells, the CD133+PD-L1+ cancer cells express higher transforming growth factor-β signaling molecules to foster a resistant tumor niche, that restricts the trafficking of the transferred macrophages by stiffened extracellular matrix, and inhibits their cell-killing capability by immunosuppressive factors. …”
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12542
Biochemical and biophysical cues of the extracellular matrix modulates stem cell fate: Progress and prospect in extracellular matrix mimicking biomaterials
Published 2025-06-01“…Overall, this review underscores the innovative applications of ECM mimicking biomaterials in biomedical engineering, emphasizing their transformative potential to modulate stem cell fate and advance regenerative medicine.…”
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12543
Integrated management for the environment care and conservation project’s results
Published 2024-03-01“…<br /><strong>Conclusions</strong>: the research project constitutes a strength that is evident in the results achieved. Despite the transformations carried out, management still needs to be improved to comply with the proposed schedule for the benefit of the environment and the health of the community.…”
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12544
Ground Deformation Characteristics Induced by Mechanized Shield Twin Tunnelling along Curved Alignments
Published 2021-01-01“…Considering the variational characteristics of the ground deformations with the magnitude of the radius of curvature, the radius of curvature of 100 m can be regarded as a critical tunnel alignment radius of curvature controlling the transformation of the curved tunnelling-induced ground deformational behaviors. …”
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12545
PHOTODYNAMIC THERAPY OF CONDYLOMATA ACUMINATE
Published 2016-06-01“…In 10% of people with the human papilloma virus develops condylomata acuminate, which can be transformed into malignant tumors. The most common treatment of condylomata acuminate is a conservative treatment, namely, the local chemical or physical destruction of the lesions and immunotherapy. …”
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12546
Stress Corrosion Behavior of Ungrouted Pretensioned Concrete Beams
Published 2018-01-01“…After 28 days, the stretching forces were released, the prestressing steel wire was allowed to regain its original length, the tensile stresses were transformed into a compressive stress in the concrete, and the stress corrosion behavior was assessed. …”
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12547
Multiwavelength Variability Analysis of the Blazar PKS 0727-11: An ~ 168 day Quasiperiodic Oscillation in the γ-Ray
Published 2025-01-01“…It is the first time that periodic variations have been detected in this source, and further supported by other methods: weighted wavelet z -transform, phase dispersion minimization, REDFIT, autoregressive integrated moving average model, and structure function analysis. …”
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12548
Dielectric Behaviour of Zn/Al-NO3 LDHs Filled with Polyvinyl Chloride Composite at Low Microwave Frequencies
Published 2014-01-01“…The composites were characterised using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM), and room temperature dielectric measurements were investigated using an RF Impedance/Material Analyzer (Agilent 4291). …”
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12549
Dynamic Analysis of Tapered Thin-Walled Beams Using Spectral Finite Element Method
Published 2019-01-01“…Then, the differential transform method (DTM) is applied to obtain the semianalytical solutions in order to formulate the spectral finite element. …”
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12550
Unraveling Power Consumption Pattern Using Multidimensional Scaling and Clustering Analysis
Published 2025-01-01“…By applying Multidimensional Scaling (MDS), we condense complex high-dimensional data into a form that reveals nuanced relationships among zones. This transformation allows for effective K-means clustering of load profiles, uncovering four distinct seasonal clusters representing shared load characteristics among NYISO zones. …”
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12551
Andrographolide suppresses cervical cancer progression by targeting angiogenesis and inducing apoptosis in a CAM-PDX model
Published 2025-02-01“…Immunohistochemical analysis revealed that AND downregulated key proteins associated with cancer cell proliferation and survival, including Ki67, B-cell lymphoma 2 (BCL-2), and Erythroblast transformation-specific-related gene (ERG). These results indicate that AND not only disrupts tumor angiogenesis but also induces cell cycle arrest and promotes apoptosis in cervical cancer cells. …”
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12552
The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking
Published 2024-12-01“…Using 3’ end anchored RNA sequencing, we mapped the alternative polyadenylation (APA) landscape following Transforming Growth Factor (TGF)-β-mediated induction of EMT in human mammary epithelial cells and found APA generally causes 3’UTR lengthening during this cell state transition. …”
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12553
A Classification Model Based on Interval Rule Inference Network with Interpretability
Published 2025-01-01“…Firstly, hybrid data with different types are transformed into an interval belief distribution for automatic generation processing. …”
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12554
Lignin-Carbohydrate Complexes Based Spherical Biocarriers: Preparation, Characterization, and Biocompatibility
Published 2017-01-01“…The carriers were stable in solution at pH 4.0~9.5. Fourier transform infrared (FT-IR) spectrum indicated that the spherical carrier was composed of lignin and polysaccharides and had a typical lignin-carbohydrate complex (LCC) structure. …”
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12555
Bagaimana Teknologi Informasi dan Komunikasi Bertransformasi Menjadi Inovasi Pelayanan Publik?
Published 2021-07-01“…Meanwhile, the Batu City government is not ready to take advantage of ICT, this is due to the absence of innovative organizational capacity and transformational leadership. Therefore, in this study the authors would like to provide advice to government organizations in building ICT-based innovation concepts, the government is not a single actor, but requires cooperation with the private sector and participation from the community as an indicator..…”
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12556
Thermal characteristics of hybrid Nanofluid (Cu-Al2O3) flow through Darcy porous medium with chemical effects via numerical successive over relaxation technique
Published 2025-01-01“…By employing proper similarity transformation, the governing PDEs are turned into ODEs. …”
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12557
Comparison of radical scavenging properties of gosypol and its derivatives in the reaction with DPPH
Published 2024-06-01“…Such a result can be an indirect confirmation that no tautomeric transformation occurs during the reaction with DPPH due to the consumption of one of the tautomers. …”
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12558
An Analysis of Meteorological Anomalies in Kamchatka in Connection with the Seismic Process
Published 2025-01-01“…For each IMF level, the instantaneous amplitudes of envelopes are calculated using the Hilbert transform. A comparison with the earthquake sequence is made using a parametric model of the intensity of two interacting point processes, which allows one to quantitatively estimate the “measure of the lead” of the time instants of the compared sequences. …”
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12559
Construction and Analysis of Emotion Computing Model Based on LSTM
Published 2021-01-01“…Second, four EEG characteristics were extracted via the wavelet transform (WT) using the LSTM-based sentiment classification network. …”
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12560
Seismic Behavior and Finite Element Analysis of Reinforced Concrete Short Columns Impacted by Oblique Earthquakes
Published 2020-01-01“…Accordingly, arranging high-strength stirrups with small spacing and the column end outer steel plate mesh both transform the failure mode from shear failure to bending shear failure. …”
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