Crystal structure and anti-inflammatory activity of (E)-7-fluoro-2-((5-methoxypyridin-3-yl)methylene)-3,4-dihydronaphthalen-1(2H)-one, C17H14FNO2 by Sun Jia-Jia, Zhang Xiao-Fan, Meng Qing-Guo, Li Hong-Juan, Wang Chun-Hua

Get full text

The global trends and distribution in tumor-infiltrating lymphocytes over the past 49 years: bibliometric and visualized analysis by Beibei Wu, Beibei Wu, Beibei Wu, Ding Luo, Ding Luo, Xuejie Wang, Xuejie Wang, Chen Qiao, Chen Qiao, Rui Li, Jian Liu, Jian Liu

Get full text

Electroacupuncture alleviates damage to myopic RGCs probably through lncRNA-XR_002789763.1-mediated mitophagy by Xuejun Wang, Qinghong Lin, Li Tian, Xiaoying Li, Teruko Fukuyama, Weijung Ten, Xiehe Kong, Yanting Yang, Xiaopeng Ma, Xingtao Zhou

Get full text

Mechanisms of wogonoside in the treatment of atherosclerosis based on network pharmacology, molecular docking, and experimental validation by Zhaohui Gong, Haixin Yang, Li Gao, Yi Liu, Qingmin Chu, Chuanjin Luo, Liang Kang, Huiqi Zhai, Qiang Xu, Wei Wu, Nan Li, Rong Li

Get full text

Application of artificial intelligence in the health management of chronic disease: bibliometric analysis by Mingxia Pan, Mingxia Pan, Rong Li, Junfan Wei, Huan Peng, Ziping Hu, Yuanfang Xiong, Na Li, Yuqin Guo, Weisheng Gu, Hanjiao Liu, Hanjiao Liu

Get full text

Comprehensive bioinformatics analysis identifies metabolic and immune-related diagnostic biomarkers shared between diabetes and COPD using multi-omics and machine learning by Qianqian Liang, Yide Wang, Zheng Li, Zheng Li, Zheng Li, Zheng Li

Get full text

Traditional Chinese acupuncture versus minimal acupuncture for mild-to-moderate knee osteoarthritis: a protocol for a randomised, controlled pilot trial by Guang-Xia Shi, Cun-Zhi Liu, Ning Sun, Yi Du, Jian-Feng Tu, Yong-Ting Li, Li-Wen Zhang, Yan Cao, Jing-Jie Zhao, Da-Chang Xiong, Hai-Kun Hou

“…Secondary end points include pain and function measurement, global change, the quality of life and the use of non-steroidal anti-inflammatory drugs (Celebrex, Pfizer) at 8, 16 and 26 weeks.Ethics and dissemination Ethical approval of this study has been granted by the Research Ethical Committee of Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University (permission number: 2016BL-010-02). …”
Get full text

Investigating Brain Structure and Functional Alterations in the Transition from Acute to Chronic Neck Pain: A Resting-State fMRI Study by Gao Z, Cui MJ, Wang HJ, Zhang J, Xu C, Ji LX

“…Zhen Gao,1,* Meng-Jie Cui,2,* Hai-Jun Wang,2 Jing Zhang,3 Cheng Xu,4 Lai-Xi Ji2 1Experimental Management Center, Shanxi University of Traditional Chinese Medicine, Taiyuan, Shanxi, 030024, People’s Republic of China; 2Second Clinical Medical College, Shanxi University of Traditional Chinese Medicine, Taiyuan, Shanxi, 030024, People’s Republic of China; 3Acupuncture and Moxibustion Department II, Affiliated Hospital of Shanxi University of Traditional Chinese Medicine, Taiyuan, Shanxi, 030024, People’s Republic of China; 4Radiology Department, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi, 030012, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lai-Xi Ji, Second Clinical Medical College, Shanxi University of Traditional Chinese Medicine, Jinci Road Section 1, No. 89, Taiyuan, Shanxi, 030024, People’s Republic of China, Email jlx@sxtcm.edu.cnPurpose: The objective of this research is to delve into the central pathological mechanisms involved in the transformation from acute to chronic pain.Patients and Methods: This study enrolled 86 individuals with acute neck pain and 89 with chronic neck pain. …”
Get full text

Association between Life’s Crucial 9 and overactive bladder: the mediating role of weight-adjusted-waist index by Hongyang Gong, Hongyang Gong, Shuqin Duan, Shaoqun Huang

Get full text

Bufalin targets the SRC-3/c-Myc pathway in chemoresistant cells to regulate metastasis induced by chemoresistance in colorectal cancer by Jinbao Chen, Chenqi Wu, Kun Yu, Jinpei Liu, Jiahua Yang, Wei Li, Xiaoxia Tang, Yihai Shi, Ke Xu, Yi Chen, Xiaoyu Qin

Get full text

Jiangzhi Granule Ameliorates JNK-Mediated Mitochondrial Dysfunction to Reduce Lipotoxic Liver Injury in NASH by Jiang Y, Xu J, Ding J, Liu T, Liu Y, Huang P, Wang Q, Zheng P, Song H, Yang L

“…Yuwei Jiang,1,* Jiaoya Xu,1,2,* Junyao Ding,1,* Tao Liu,1 Yang Liu,1,3 Ping Huang,1 Qianlei Wang,1 Peiyong Zheng,1 Haiyan Song,1 Lili Yang1 1Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 2Department of Gout, Guanghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 3Teaching Experiment Center, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Haiyan Song; Lili Yang, Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 725 South Wanping Road, Shanghai, 200032, People’s Republic of China, Email songhy@126.com; yanglili76@126.comPurpose: Mitochondrial dysfunction mediated by c-Jun N-terminal kinase (JNK) plays an important role in lipotoxic liver injury in nonalcoholic steatohepatitis (NASH). …”
Get full text

Research Progress on Neural Processing of Hand and Forearm Tactile Sensation: A Review Based on fMRI Research by Chen H, Fu S, Zhi X, Wang Y, Liu F, Li Y, Ren F, Zhang J, Ren L, Wang Y

“…Hao Chen,1,* Shifang Fu,2,* Xiaoyu Zhi,2 Yu Wang,2 Fanqi Liu,2 Yuetong Li,2 Fengjiao Ren,2 Junfeng Zhang,1,3,4 Longsheng Ren,1 Yanguo Wang2 1Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, People’s Republic of China; 2Rehabilitation Department, Tianjin University of Traditional Chinese Medicine Second Affiliated Hospital, Tianjin, 300250, People’s Republic of China; 3Rehabilitation Center, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, People’s Republic of China; 4National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, 300381, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yanguo Wang, Tianjin University of Traditional Chinese Medicine Second Affiliated Hospital, Tianjin, 300250, People’s Republic of China, Email tjwangyanguo@163.comAbstract: Tactile perception is one of the important ways through which humans interact with the external environment. …”
Get full text

Acupuncture as prophylaxis for chronic migraine: a protocol for a single-blinded, double-dummy randomised controlled trial by Claire Shuiqing Zhang, Bin Li, Lin Zeng, Lu Liu, Luo-peng Zhao, Kelun Wang, Jingxia Zhao, Linpeng Wang, Xianghong Jing

“…The primary outcome is the reduction of monthly headache days, and the secondary outcomes include the reduction of the number of days with acute headache medications, and changes of Migraine Disability Assessment, Migraine-Specific Quality of Life Questionnaire, Headache Impact Test, State-Trait Anxiety Inventory-trait, and Beck Depression Inventory-II scores from baseline to endpoints.Ethics and dissemination Ethical approval of this study was granted by the Research Ethical Committee of Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University (2017BL-045-01). …”
Get full text

Tetrastigma hemsleyanum as a feed additive: modulating gut microbiota for enhancing nutritional transport and growth performance in Jinhua yellow chickens by Chao Lu, Yun Xiang, Kewei Xu, Fengrui Gao, Shaofeng Zhu, Fangfang Lou, Lu Liu, Xin Peng

Get full text

Risk factors analysis and prediction model establishment of acute kidney injury after heart valve replacement in patients with normal renal function by Xiaofan Huang, Xiaofan Huang, Xiangyu Sun, Jiangang Song, Yongqiang Wang, Jindong Liu, Jindong Liu, Yu Zhang, Yu Zhang

Get full text

Electroacupuncture for mild-to-moderate dry eye: study protocol for a multicentre, randomised, single-blind, sham-controlled trial by Yue Zhao, Guang Yang, Yun-Qiong Lu, Mei-Yan Li, Jue Hong, Yan-Ting Yang, Xue-Jun Wang, Xie-He Kong, Zhao Ma, Xin-Yun Huang, Yue-Lan Zou, Xing-Tao Zhou, Xiao-Peng Ma

“…The secondary outcomes include tear meniscus height, the Schirmer I test, corneal and conjunctival sensation, the ocular surface disease index, corneal fluorescein staining, the numerical rating scale and the Chinese DE-related quality of life scale.Ethics and dissemination The trial protocol and informed consent were approved by the Ethics Committee of Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine (identifier: 2021–119), Shanghai Eye Disease Prevention and Treatment Center (identifier: 2022SQ003) and Eye and ENT Hospital of Fudan University (identifier: 2022014).Trial registration number NCT05552820.…”
Get full text

Intensive care and rehabilitation for an elderly patient with acute exacerbation of chronic renal failure (1例老年慢性肾衰竭急性加重患者的ICU康复护理) by KONG Tongtong (孔彤彤), SU Junqing (苏俊青), LIU Shuhua (刘书华)

Get full text

PPARγ and Its Agonists in Chronic Kidney Disease by Yuhua Ma, Manman Shi, Yuxin Wang, Jian Liu

Get full text

A cross-tissue transcriptome-wide association study identified susceptibility genes for age-related macular degeneration by Hongfan Yang, Haofei Huang, Kunlin Pu

Get full text

Development of research on HIV-associated neurocognitive disorder and emerging trends: a visualization analysis via CiteSpace by Tingting Zhou, Xuannan Chen, Yu Lai

Get full text