Machine learning based models for predicting presentation delay risk among gastric cancer patients by Huali Zhou, Huali Zhou, Qiong Gu, Rong Bao, Liping Qiu, Yuhan Zhang, Fang Wang, Wenlian Liu, Lingling Wu, Li Li, Yihua Ren, Lei Qiu, Qian Wang, Gaomin Zhang, Xiaoqing Qiao, Wenjie Yuan, Juan Ren, Min Luo, Rong Huang, Qing Yang, Qing Yang

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A systematic review and meta-analysis of influencing factors of postoperative wound healing in patients with anal fistula (肛瘘患者术后伤口愈合影响因素系统评价与Meta分析)... by CHEN Qi (陈祺), LIU Zhiping (刘志平), BAI Jianying (白建英), LIU Bo (刘博), FENG Jiangxu (冯江雪)

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Effect of Extracorporeal Shock Wave combined with Occupational Therapy on Forearm Pronation Disorder in Children with Spastic Cerebral Palsy by Hezeng LIU, Yong ZHAO, Bingxu JIN, Chuntao ZHANG, Yang YANG, Miaotao WU, Xiaoli WANG, Jixiang CHENG

“…Objective:To observe the effect of extracorporeal shock wave combined with occupational therapy therapy on forearm pronation disorder in children with spastic cerebral palsy(SCP).Methods:A total of 42 children with SCP were randomly divided into the control group and the observation group, with 21 cases in each group in the children rehabilitation department of the affiliated Nanhai maternity and children's Hospital of Guangzhou university of traditional Chinese medicine from January to December 2019.The control group was given targeted occupational therapy, including upper limb forearm pronator stretching therapy, neurophysiological therapy(Bobath technology), proprioceptive neuromuscular facilitation therapy(PNF); game type occupational training including placing objects in forearm supination position, supination grasping stick, supination fetching game, palm and back game, etc..The above training was conducted once a day, 30 minutes per time, six times a week, three months as a course of treatment, continuous treatment for two courses.The observation group was given extracorporeal shock wave therapy on the basis of the control group.The child with SCP was in a comfortable position and the forearms of the upper limbs were placed on the plane so that it could free its own gravity.The abdomen of pronator teres muscle was impacted with the probe of shock wave therapeutic instrument(pressure intensity: 1.0-1.5 bar;frequency: 8-10 Hz;impact times: 1 000-2 000 times).Three to five minutes each time, once every three days, twice a week, three months as a course of treatment, continuous treatment for two courses.Before treatment, after treatment for three months and six months, the modified Ashworth scale(MAS)was used to evaluate the spasticity of forearm pronator muscles;the active range of motion(AROM)of forearm supination was measured by joint range of motion protractor;and the fine motor quotient(FMQ)of hands was evaluated by Peabody development motor scale-fine motor(PDMS-FM).Results:Before treatment, there was no significant difference in MAS score, AROM angle and FMQ score between two groups(<italic>P</italic>&gt;0.05).Compared with before treatment, the MAS scores of the two groups decreased significantly after treatment for three and six months, and the AROM angle and FMQ score increased significantly, the difference was statistically significant(<italic>P</italic>&lt;0.05).Compared with the control group at the same time after treatment, MAS score of the observation group was significantly lower, AROM angle and FMQ score were significantly higher, the difference was statistically significant(<italic>P</italic>&lt;0.05).Conclusion:Extracorporeal shock wave combined with occupational therapy therapy can effectively improve the degree of upper limb spasticity and forearm supination joint activity in children with spastic cerebral palsy, and improve the fine motor function of hands.…”
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Exploration of the Immune-Related Signatures and Immune Infiltration Analysis in Melanoma by Ai-lan Li, Yong-mei Zhu, Lai-qiang Gao, Shu-yue Wei, Ming-tao Wang, Qiang Ma, You-you Zheng, Jian-hua Li, Qing-feng Wang

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Correlation between night sweats and season fluctuation in China by Cai Chen, Meng Li, Fulai Peng, Danyang Lv, Xiao Ding, Chongxuan Tian, Weilian Ren, Xiangwei Meng, Tiefeng Sun, Yi Wang, Haitao Du, Fengxia Wu, Wei Li, Ping Wang

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Population Pharmacokinetic of Epidural Sufentanil in Labouring Women: A Multicentric, Prospective, Observational Study by Nie Y, Sun X, Cao R, Tang S, Zhou Q, Zhou M, Chen Z, Huang S

“…Yuyan Nie,1,&ast; Xingfeng Sun,1,&ast; Rong Cao,2 Songjiang Tang,3 Qun Zhou,4 Min Zhou,5 Zuolei Chen,6 Shaoqiang Huang1 1Department of Anesthesiology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, People’s Republic of China; 2Department of Anesthesiology, Chengdu Women’s and Children’s Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 3Department of Anesthesiology, the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, People’s Republic of China; 4Department of Anesthesiology, Jiangxi Maternal and Child Health Hospital, Nanchang, People’s Republic of China; 5Department of Anesthesiology, Fujian Provincial Maternity and Children’s Hospital, Fuzhou, People’s Republic of China; 6Department of Anesthesiology, the Affiliated Hospital of Qingdao Binhai University, Qingdao, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Shaoqiang Huang, Department of Anesthesiology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, 200090, People’s Republic of China, Tel/Fax +86-021-33189900, Email drhuangsq@163.comPurpose: The effects of sufentanil-ropivacaine combination on the parturient women and the course of labor have been well documented. …”
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Inverse relationship of oxidative balance score with hyperuricemia among Chinese adults: a population-based cross-sectional study by Hewei Peng, Ying Han, Jingru Huang, Wenxin Qiu, Huajing Chang, Jiangwang Fang, Xian-E Peng

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Efficacy of wearable transcutaneous electrical acupoint stimulation bracelet on moderate-to-severe postoperative nausea and vomiting in patients after general anesthesia: a study p... by Peng Ding, Dong-yu Zheng, Hong-wei Zhu, Ming Gong, Yong-qiang Wang, Ling-yan Jin, Guang-li Ren, Hui-jing Shi, Yong-hua Li

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Application of deep learning model based on unenhanced chest CT for opportunistic screening of osteoporosis: a multicenter retrospective cohort study by Chengbin Huang, Dengying Wu, Bingzhang Wang, Chenxuan Hong, Jiasen Hu, Zijian Yan, Jianpeng Chen, Yaping Jin, Yingze Zhang

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Development and Evaluation of Aloperine-Loaded Nanostructured Lipid Carriers for the Treatment of Pulmonary Arterial Hypertension by Liu H, Liu S, Ma P, Ma L, Liu Y, Zhao F, Zhou R

“…Hui Liu,1,&ast; Siyun Liu,1,&ast; Pengsheng Ma,1 Long Ma,1 Yuxin Liu,1 Fang Zhao,2 Ru Zhou1,3,4 1School of Pharmacy, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 2General Hospital of Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 3NHC Key Laboratory of Metabolic Cardiovascular Diseases Research, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 4Ningxia Characteristic Traditional Chinese Medicine Modernization Engineering Technology Research Center, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Ru Zhou, School of Pharmacy, Ningxia Medical University, Xingqing, Ningxia, Yinchuan, 750004, People’s Republic of China, Email zhou-ru926@163.com Fang Zhao, General Hospital of Ningxia Medical University, Xingqing, Ningxia, Yinchuan, 750004, People’s Republic of China, Email ysj119zf@163.comObjective: This study focuses on the development and evaluation of nanostructured lipid carriers (NLCs) loaded with aloperine as a potential therapeutic approach for the treatment of pulmonary arterial hypertension.Methods: The NLCs were designed to enhance the solubility, stability, and bioavailability of aloperine, a compound with vasodilatory and anti-inflammatory properties. …”
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Microplastics mediates the spread of antimicrobial resistance plasmids via modulating conjugal gene expression by Qiu E. Yang, Zhenyan Lin, Dehao Gan, Minchun Li, Xuedan Liu, Shungui Zhou, Timothy R. Walsh

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Actors influencing cancer-related fatigue and the construction of a risk prediction model in lung cancer patients by Mei-Ning Zhang, Yi-Chen Zhou, Zhu Zeng, Cun-Liang Zeng, Bo-Tao Hou, Gui-Rong Wu, Qiao Jiao, Dai-Yuan Ma

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PNPO‐Mediated Oxidation of DVL3 Promotes Multiple Myeloma Malignancy and Osteoclastogenesis by Activating the Wnt/β‐Catenin Pathway by Zhendong Deng, Shanliang Sun, Nian Zhou, Yumeng Peng, Long Cheng, Xichao Yu, Yuxia Yuan, Mengjie Guo, Min Xu, Yuexin Cheng, Fan Zhou, Nianguang Li, Ye Yang, Chunyan Gu

“…Celastrol, a natural compound derived from traditional Chinese medicine, exhibits significant anticancer effects. …”
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A bibliometric analysis of optic atrophy from 2003 to 2023: research trends and hot spots by Liyuan Wang, Liyuan Wang, Liyuan Wang, Tianyang Yu, Tianyang Yu, Runze Wang, Lijuan Fu, Lijuan Fu, Feixue Dong, Feixue Dong, Shuang Zhao, Shuang Zhao, He Sun, He Sun, Yang Gao

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Exosomes Derived from CXCR4-Overexpressing BMSC Promoted Activation of Microvascular Endothelial Cells in Cerebral Ischemia/Reperfusion Injury by Xutong Li, Ye Zhang, Yong Wang, Dan Zhao, Chengcheng Sun, Shaoting Zhou, Dongsheng Xu, Jing Zhao

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Huanglian Ejiao Decoction Alleviates Ulcerative Colitis in Mice Through Regulating the Gut Microbiota and Inhibiting the Ratio of Th1 and Th2 Cells by Tang J, Hu Y, Fang J, Zhu W, Xu W, Yu D, Zheng Z, Zhou Q, Fu H, Zhang W

“…Jingyi Tang,1,2,&ast; Yingnan Hu,1,3,&ast; Jintao Fang,1,&ast; Weihan Zhu,1,&ast; Wenjun Xu,1 Dian Yu,1 Zhipeng Zheng,4 Qiujing Zhou,4 Huiying Fu,4 Wei Zhang1,4 1The Second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, 310053, People’s Republic of China; 2Lanxi Hospital of Traditional Chinese Medicine, Jinhua, 321100, People’s Republic of China; 3The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510510, People’s Republic of China; 4The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310005, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Wei Zhang; Huiying Fu, Email zhangweils1968@163.com; fhy131@126.comBackground: Huanglian-ejiao decoction (HED) is a Chinese traditional medicinal formula evolved from the Shanghan Lun (Treatise on Febrile Diseases). …”
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Acceptance of artificial intelligence clinical assistant decision support system to prevent and control venous thromboembolism among healthcare workers: an extend Unified Theory of... by Jingxian Wang, Yun Zhou, Yun Zhou, Kai Tan, Zhigang Yu, You Li

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Development and experimental validation of dephosphorylation-related biomarkers to assess prognosis and immunotherapeutic response in gliomas by Hui Tang, Xuping Yang, Xuping Yang, Guoqian Li, Ke Peng, Yang Sun, Longyang Jiang, Longyang Jiang, Yilan Huang, Yilan Huang

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Exploring the Anti-depression Mechanism of Polygonatum ordoratum Based on GEO Database Combined with Network Pharmacology and Molecular Docking Technology by Zhenxu JIANG, Chaoxing WANG, Yuliang WANG, Hong ZHAO, Yu SHEN, Shiqing SUN, Yongzhe MA, Mingming SONG, Yu ZHANG

“…Objective: This study aims to identify the potential targets and signaling pathways of the rhizome of Polygonatum odoratum (Yuzhu in traditional Chinese medicine) in the treatment of depression, through bioinformatics and network pharmacology, and to preliminarily explore its efficacy through PC12 cell experiments. …”
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Quantitative relationships between elastic modulus of rod and biomechanical properties of transforaminal lumbar interbody fusion: a finite element analysis by Jie Li, Zengfeng Du, Shuai Cao, Teng Lu, Zhongwei Sun, Hongyu Wei, Haopeng Li, Ting Zhang

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