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PfFBXO1 is essential for inner membrane complex formation in Plasmodium falciparum during both asexual and transmission stages
Published 2025-02-01“…Here we demonstrate that PfFBXO1 (PF3D7_0619700) is critical for both asexual segmentation and gametocyte maturation. In Toxoplasma gondii, the FBXO1 homolog, TgFBXO1, is essential for the development of the daughter cell scaffold and a component of the daughter cell IMC. …”
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62
Sero-molecular prevalence of toxoplasmosis in hemodialysis and peritoneal dialysis patients in Markazi Province, Iran
Published 2025-01-01“…Abstract Background Infectious diseases, particularly parasitic infections such as toxoplasmosis, contribute significantly to the morbidity and mortality of hemodialysis patients. Toxoplasma gondii infection poses serious risks, especially to immunocompromised individuals. …”
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63
Investigation of TORCH seroprevalence in a tertiary university hospital
Published 2024-04-01“…This study aimed to investigate the seroprevalence of TORCH (Toxoplasma gondii, other agents, Rubella, Cytomegalovirus (CMV), and herpes simplex virus (HSV)) in pregnant women at a tertiary university hospital and determine the level of immunity in the community. …”
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64
Characteristics of Plasmodium vivax apicomplexan amino acid transporter 8 (PvApiAT8) in the cationic amino acid transport
Published 2025-02-01“…Sequence and structural analyses revealed a conserved binding pocket for cationic amino acids in Plasmodium species, distinct from that in Toxoplasma gondii NPT1. These findings highlight the potential of targeting PvApiAT8 in developing new treatments for P. vivax malaria.…”
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65
Prevalence Survey of Selected Bovine Pathogens in Water Buffaloes in the North Region of Brazil
Published 2014-01-01“…The present study was therefore conducted to investigate the epidemiological of Toxoplasma gondii, Neospora caninum, Anaplasma marginale, Babesia bigemina, and Babesia bovis in water buffaloes in the north region of Brazil. …”
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66
Evaluation of the Tyrosine and Dopamine Serum Levels in Experimental Infected BALB/c Mice with Chronic Toxoplasmosis
Published 2021-01-01“…Materials and Methods. Toxoplasma gondii (Prugniaud strain II) was injected intraperitoneally into BALB/c mice to induce chronic toxoplasmosis. …”
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67
Analysis and Characterization of the Immunogenicity of Rhoptry Protein 18
Published 2025-02-01“…Rhoptry protein 18 (ROP18) is a key virulence factor secreted into host cells during the invasion of Toxoplasma gondii ( T. gondii ) and plays an important role in the pathogenesis of infection. …”
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68
Evaluation of Awareness, Knowledge, Attitude and Practices Related to Toxoplasmosis Among Females in Algeria
Published 2024-12-01“…Toxoplasmosis is a major veterinary and public health issue affecting humans and animals, where felids represent the definitive hosts of the causative agent <i>Toxoplasma gondii</i>. While the infections are mostly asymptomatic, the disease could be severe in immune-compromised patients and pregnant women. …”
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69
Bibliometric analysis of neutrophil extracellular traps induced by protozoan and helminth parasites (2008–2024)
Published 2025-01-01“…Current research focuses on malaria, Toxoplasma gondii, Besnoitia besnoiti, nematodes, and the mechanisms of NETs production and their effects on parasites and host cells. …”
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70
Historical Spatial Distribution of Zoonotic Diseases in Domestic, Synanthropic, and Wild Animals in the Mexican Territory of the Yucatan Peninsula
Published 2021-01-01“…The territory harbors a wide variety of tropical zoonotic pathogens, including Trypanosoma cruzi, Leptospira interrogans, Toxoplasma gondii, Leishmania mexicana, Dirofilaria immitis, and Rickettsia felis. …”
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71
Latent Toxoplasmosis among Breast Cancer Patients in Jahrom, South of Iran
Published 2023-01-01“…Hence, this study is aimed at screening the status of Toxoplasma gondii infection among breast cancer patients by serological and molecular methods and determining their associated risk factors in Jahrom County, Fars Province, south of Iran. …”
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72
Multilevel Precision-Based Rational Design of Chemical Inhibitors Targeting the Hydrophobic Cleft of Apical Membrane Antigen 1 (AMA1)
Published 2016-06-01“…Toxoplasma gondii is an intracellular Apicomplexan parasite and a causative agent of toxoplasmosis in human. …”
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73
Comparative evaluation of funduscopy, PCR and serology in the diagnosis of ocular toxoplasmosis at ECWA Eye Hospital, Kano
Published 2025-01-01“…Objective Ocular toxoplasmosis, caused by Toxoplasma gondii, is a significant cause of posterior uveitis and vision impairment globally. …”
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74
Identification of a New Pentafluorosulfanyl-Substituted Chalcone with Activity Against Hepatoma and Human Parasites
Published 2025-01-01“…They were tested for activity against two liver cancer cell lines (HepG2 and HuH-7) and protozoal parasites (<i>Toxoplasma gondii</i> and <i>Leishmania major</i>). Unspecific toxicity and expression of Hsp90 and Hsp70 upon treatment were analyzed in liver cancer cells. …”
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75
Fatal toxoplasmic encephalitis triggered by anti-TNF therapy
Published 2025-02-01“…Reactivation of a latent infection by the protozoan parasite Toxoplasma gondii can result in severe neurologic outcomes and even death. …”
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76
Assessment of physiological status of felids as indicator of their welfare in the wild
Published 2015-03-01“…Pallas cats had the lowest occurrence of positive reactions to 4 pathogens: Toxoplasma gondii (12.5%), Mycoplasma sp. (12.5%), influenza A (7.1%), and feline leukemia virus (8.3%). …”
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77
Aspects of Toxoplasma Infection on the Reproductive System of Experimentally Infected Rams (Ovis Aries)
Published 2009-01-01“…The rams presented clinical alterations (hyperthermia and apathy) related to toxoplasmosis in both groups infected with Toxoplasma gondii. All the inoculated rams responded to antigenic stimulus, producing antibodies against T. gondii from postinoculation day 5 onwards. …”
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78
Neospora caninum infection specifically suppresses the expression of a host lncRNA XR_001919077.1 to facilitate parasite propagation by modulating host cell mitochondrial function...
Published 2025-02-01“…In the present study, N. caninum, but not Toxoplasma gondii, which has similar morphological and biological features to N. caninum, specifically suppresses the expression of a host lncRNA, XR_ 001919077.1, to impair host’s defense through the competitive endogenous RNA mechanism to modulate the host cell mitochondrial function and autophagy to facilitate parasite propagation. …”
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Pulmonary Toxoplasmosis Diagnosed on Transbronchial Lung Biopsy in a Mechanically Ventilated Patient
Published 2020-01-01“…Toxoplasma gondii is a protozoan parasite that infects up to a third of the world’s population. …”
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