Protective Effect of Liposome-Encapsulated Glutathione in a Human Epidermal Model Exposed to a Mustard Gas Analog by Victor Paromov, Sudha Kumari, Marianne Brannon, Naga S. Kanaparthy, Hongsong Yang, Milton G. Smith, William L. Stone

“…This study provides a rationale for use of antioxidant liposomes against HD toxicity in the skin considering further verification in animal models exposed to HD.…”
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Evolution of the Radiation Shielding, Optical, and Luminescence Properties of PbO₂-SiO₂ Glass Systems and the Influence of Rare Earth Elements (Eu, Ce, Yb) by Mioara Zagrai, Ramona-Crina Suciu, Radu Cristian Gavrea, Vasile Rednic

“…Traditional radiation shielding materials, like lead and concrete, face challenges due to toxicity and weight. Glass materials provide an alternative, offering transparency and efficiency. …”
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Cytotoxic evaluation of a mixture of four commonly used pesticides on mammalian cell lines by Prudence Agnandji, Eugène S. Attakpa, Fabrice Cazier

“…The cytotoxicity was compared to a quantitative structure-activity relationship for baseline toxicity, and chemicals were confirmed as baseline toxicants in this cell line. …”
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Fatal intoxication after oral ingestion of amphetamine: Two case reports by Evelyn Pawlik, Felix Mayer, Oliver Temme

“…The amphetamine concentrations of both cases are compared and the distribution in the body is discussed. The toxicity of the amphetamine by-products on the human body remains unclear and is subject of further studies.…”
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Genetic Variations of Glutathione S-Transferase Influence on Blood Cadmium Concentration by Nitchaphat Khansakorn, Waranya Wongwit, Prapin Tharnpoophasiam, Bunlue Hengprasith, Lerson Suwannathon, Suwannee Chanprasertyothin, Thunyachai Sura, Sming Kaojarern, Piyamit Sritara, Jintana Sirivarasai

“…This study indicated that polymorphisms of GSTP1 combined with GSTT1 and/or GSTM1 deletion are likely to influence on individual susceptibility to cadmium toxicity.…”
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Lamotrigine-Valproic Acid Interaction Leading to Stevens–Johnson Syndrome by Marta Vázquez, Cecilia Maldonado, Natalia Guevara, Andrea Rey, Pietro Fagiolino, Antonella Carozzi, Carlos Azambuja

“…As this reactive metabolite is detoxified mainly by enzymatic reactions, involving microsomal epoxide hydrolase and/or GSH-S-transferases and these enzymes are polymorphically expressed in humans, arene oxide toxicity is increased when epoxide hydrolase or GSH-S-transferases is either defective or inhibited or a depletion of intracellular glutathione levels is taking place. …”
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Nephroprotective effects of Foeniculum vulgare mill (Apiaceae Family) hydromethanol leaf extract against cisplatin-induced nephrotoxicity on Swiss albino mice by Kibur Hunie Tesfa, Chernet Desalegn Gebeyehu, Tiget Ayelgn Mengstie, Hiwot Tezera Endale

“…Therefore, it is mandatory to seek effective, affordable, and safe drugs for the prevention and curative effects of kidney toxicity caused by cisplatin. Thus, this study evaluated the effects of Foeniculum vulgare Mill hydro-methanolic crude leaf extract on cisplatin-induced nephrotoxicity in Swiss albino mice. …”
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Rapid adsorption of selenium removal using iron manganese-based micro adsorbent by Sundus Saeed Qureshi, Sheeraz Ahmed Memon, Rafi-ul-Zaman, Nanik Ram, Sumbul Saeed, Nabisab Mujawar Mubarak, Rama Rao Karri

“…Abstract Selenium in wastewater is of particular concern due to its increasing concentration, high mobility in water, and toxicity to organisms; therefore, this study was carried out to determine the removal efficiency of selenium using iron and manganese-based bimetallic micro-composite adsorbents. …”
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Lipotoxicity and metabolic disorders at obesity by V. T. Ivashkin, M. V. Mayevskaya

“…It is possible to explain lipotoxicity phenomenon as follows: in conditions of insulin resistance glucose stops to be an energy source and is substituted by lipolysis, therefore a plenty of free fatty acids is formed, having potential of toxicity and realizing metabolic disorders in target organs: the liver, the pancreas, muscles. …”
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Exploring northeast India’s culturable soil Actinomycetia for potent antibacterial agents against gram-positive bacterial pathogens of clinical importance by Aditya Narayan Konwar, Surajit Basak, Shalini Gurumayum, Jagat Chandra Borah, Debajit Thakur

“…Chemical analyses using FTIR and GC-MS identified key bioactive compounds, including Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(2-methylpropyl)- and Phenol 3,5-bis(1,1-dimethylethyl), known for their antimicrobial properties. Toxicity studies against animal liver cell lines indicated that the ethyl acetate extract was non-toxic at concentrations below 125 µg/mL, compared to Vancomycin, which was found to be hepatotoxic at similar concentrations. …”
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5-Fluorouracil-β-Cyclodextrin conjugates:Linker strategies to enhance the anticancer efficacy and reduce the side effects by Liangliang Hu, Ting Meng, Davies Marabada, Zhichao Jin, Qing Huang, Shijie Wei, Zhizhong Wang

“…These findings not only demonstrated that 5-Fluorouracil-β-Cyclodextrin conjugates exhibits superior antitumor activity and reduced toxicity but also suggest that the linker plays a crucial role in determining both the efficacy of drug conjugates as an anticancer agent and its associated adverse effects. …”
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An Efficient Protocol for Deriving Liver Stem Cells from Neonatal Mice: Validating Its Differentiation Potential by Sugapriya Dhanasekaran, Devilakshmi Sithambaram, Kavitha Govarthanan, Bijesh Kumar Biswal, Rama S. Verma

“…Finally, we developed a reproducible, efficient protocol for isolation of LDSCs with functional hepatocytes differentiation potential, which further can be used as in vitro model system for assessing drug toxicity assays in various preclinical trials.…”
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Application of Nano-Titanium Dioxide in Food Antibacterial Packaging Materials by Jiarui Li, Dequan Zhang, Chengli Hou

“…Nano-titanium dioxide (nano-TiO₂) with PDI characteristics has attracted the interest of many researchers with its elevated efficiency, broad-spectrum antibacterial resistance, low cost, safety, and non-toxicity. Nano-TiO₂ photodynamic antibacterial properties have been studied extensively and has a great application value in the field of food packaging. …”
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Formulation of new drug delivery systems for insulin from natural bioactive biocompatible polymers by Howida A. Fetouh, Engy E. A. Aleem, Najiyah H. Mohammed, Jihad M. Abd-Almajeed Aldesouky, Amel M. Ismail

“…Traces amount additives were below toxicity limits. Guar gum increased the numbers of the functional groups of the polymer carrier. …”
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Three months of weekly rifapentine plus isoniazid for TB prevention among people with HIV by R. Borse, B. Randive, S. Mattoo, P. Malik, H. Solanki, A. Gupta, R.E. Chaisson, V. Mave, N. Suryavanshi

“…Of these, 20 (4%) discontinued TPT due to toxicity,17 (3.8%) lost to follow-up, one (0.2%) had breakthrough rifampicin-sensitive TB, and 464 (92%) completed 3 HP TPT. …”
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Chemical test and cellular bioactivities and flavor enhancer properties of mung bean protein via glycation reaction by Srisukpachin Nuttakarn, Tabtimmai Lueacha, Sedtananun Saranya, Laohakunjit Natta, Sonklin Chanikan

“…MRP demonstrated both low cytotoxicity and significant anti-inflammatory effects. MRP exhibited non-toxic in Vero cells at 10 mg/mL and it significantly suppressed nitric oxide (NO) release to 18.62 µM with non-toxicity in the murine macrophage; RAW 264.7 at a concentration of 1 mg/mL.…”
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Growth and bioactivity of Phellinus linteus in the mushroom farm, at different cultivation times by Jitchum Supapitch, Tabtimmai Lueacha, Phoohinkong Weerachon, Thumthanaruk Benjawan, Zhang Xiaoshuan, Suttisintong Khomson, Rungsardthong Vilai

“…Further studies of their toxicity on normal cells would benefit the application of PL extract.…”
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Structural bioinformatics for rational drug design by Soroush Mozaffari, Agnethe Moen, Che Yee Ng, Gerry A.F. Nicolaes, Kanin Wichapong

“…Artificial intelligence models, alongside traditional physics-based simulations, now play an important role in predicting key properties such as binding affinity and toxicity, contributing to more informed decision-making, particularly early in the drug discovery process. …”
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Biomonitoring potential of trace metal accumulation and bioavailability in coral skeletons and reef sediments of Persian Gulf: A comparative study by Seyed Hassan Mousavi, Mehdi Gholamalifard, Seyed Mahmoud Ghasempouri

“…According to the sediment pollution indices, Site I showed the highest potential toxicity to biota, followed by Site II and then Site III. …”
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Helicobacter pylori promotes intestinal flora imbalance and hepatic metabolic disorders under arsenic stress by Linmin Zhong, Qiling Yang, Yiming Shao, Shanwen Hu, Lianxian Guo

“…Herein, we hypothesize that H. pylori infection may exacerbate the intestinal flora imbalance and hepatic metabolic disturbances caused by arsenic exposure, which may disrupt enterohepatic homeostasis and potentially increase biological susceptibility to heavy metal toxicity.…”
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