Life Threatening Severe QTc Prolongation in Patient with Systemic Lupus Erythematosus due to Hydroxychloroquine by John P. O’Laughlin, Parag H. Mehta, Brian C. Wong

“…The patient was noted to have mild prolongation of the QT interval on electrocardiogram prior to initiation of hydroxychloroquine therapy which was exacerbated by its use and may have been caused due to toxicity from underlying renal failure.…”
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Acute Renal Failure Secondary to Inadvertent Propylene Glycol Overdose with Single-Day High-Dose Vitamin D (Stosstherapy) by David H. Jelley, Deborah Zayneb Mohamad Ali, Michelle Condren

“…We present an as yet unreported complication of acute renal injury due to propylene glycol toxicity in a 7-month infant treated with vitamin D stosstherapy. …”
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Arsenic Contamination of Groundwater: A Review of Sources, Prevalence, Health Risks, and Strategies for Mitigation by Shiv Shankar, Uma Shanker, Shikha

“…The paper also critically reviews the As led human health risks, its uptake, metabolism, and toxicity mechanisms. The paper provides an overview of the state-of-the-art knowledge on the alternative As free drinking water and various technologies (oxidation, coagulation flocculation, adsorption, and microbial) for mitigation of the problem of As contamination of groundwater.…”
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Emergency Evacuation of Hazardous Chemical Accidents Based on Diffusion Simulation by Jiang-Hua Zhang, Hai-Yue Liu, Rui Zhu, Yang Liu

“…The recent rapid development of information technology, such as sensing technology, communications technology, and database, allows us to use simulation experiments for analyzing serious accidents caused by hazardous chemicals. Due to the toxicity and diffusion of hazardous chemicals, these accidents often lead to not only severe consequences and economic losses, but also traffic jams at the same time. …”
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Piperine: Chemical, biological and nanotechnological applications by Quijia Christian Rafael, Araujo Victor Hugo, Chorilli Marlus

“…The present article provides a comprehensive review of PIP research in the last years concerning its chemical properties, synthesis, absorption, metabolism, bioavailability and toxicity. The reviewed PIP literature has shown many pharmacological properties, such as antidiabetic, antidiarrheal, antioxidant, antibacterial, and anti-parasitic activity of PIP. …”
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Toxicological Review of Anticancer Plants Used in Traditional Medicine in Morocco by Soufiane Drioua, Abha Cherkani-Hassani, Otman El-Guourrami, Mouna Ameggouz, Ahmed Zahidi, Abdelhakim Bouyahaya, Sayyed Ibrahim Shah, Yaser Mohammed Al-Worafi, Long Chiau Ming, Hanane Benzaied, Anass Doukkali

“… In Morocco, traditional medicine utilizes many toxic plants for cancer treatment, despite a lack of scientific evidence supporting their effectiveness. …”
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Midregion PTHrP and Human Breast Cancer Cells by Claudio Luparello

“…The midregion PTHrP domain (38-94)-amide was found to restrain growth and invasion in vitro of some breast cancer cell lines, causing striking toxicity and accelerating death; the most responsive being MDA-MB231, whose tumorigenesis was also attenuated in vivo. …”
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TOXICOLOGIC CHARACTERISTICS OF THE PREVENTIVE IODINE-CONTAINING PREPARATION “VANGTSEYOD” by T. V. Kruchinkina, Yu. A. Gavrilov, G. A. Gavrilova

“…Studies of the preparation safety performed on white mice showed that “Vangtseyod” does not have acute toxicity. It’s inclusion into mice diet at 1.0 and 2.0 g/kg dose during two months did not induce any signs of chronic intoxication as 100% mice of experimental group survived in comparison with the control group (57%). …”
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Recurrence of Chronic Myeloid Leukemia during Pregnancy Subsequently Achieving Complete Medical Remission by Sasha Mikhael, Ashlee Pascoe, Joseph Prezzato

“…Much controversy exists regarding continuation versus discontinuation of its use in pregnancy with some studies suggesting safety of TKIs before and during pregnancy and others reporting toxicity and adverse outcomes. TKIs have become a well-established treatment option for CML, significantly improving prognosis, and yet have been reported to be fetotoxic. …”
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Oral Cavity Squamous Cell Carcinoma: Impact of Clear Margin Distance on Locoregional Control in Patients Undergoing Postoperative Radiotherapy by Erkan Topkan MD, Efsun Somay PhD, Ugur Selek MD

“…We congratulate Lang and colleagues for their study investigating the impact of resection margin (RM) size on locoregional control (LC) outcomes, overall survival (OS), progression-free survival (PFS), and treatment-related toxicity in 162 patients with oral cavity squamous cell carcinoma (OCSCC) who received postoperative radiotherapy (PORT).1 In this study, 77 (47.5%), 22 (13.6%), and 63 (38.9%) patients had involved (5 mm) RM, respectively. …”
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The Challenge of Recurrent Hepatitis C Virus in Liver Transplant Recipients by Paul J Marotta

“…Interferon-based antiviral therapy is challenging to use in this patient population because of significant toxicity. Nevertheless, these agents have some efficacy, and pegylated interferons, which are now being used more frequently, achieve superior response rates. …”
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Synthesis and Catalytic and Biological Activities of Silver and Copper Nanoparticles Using Cassia occidentalis by Manjul Gondwal, Geeta Joshi nee Pant

“…The AgNPs showed lower haemolysis (1.7%) exhibiting lesser toxicity as compared to CuNPs. The CuNPs have better catalytic ability for the reduction of 4-nitrophenol and 2-nitrophenol as compared to AgNPs.…”
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Linezolid and serotonin syndrome by Haytham A. Wali

“…The Hunter Serotonin Toxicity Criteria have superior sensitivity and specificity over the Sternbach Criteria for diagnosis. …”
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Organic Alternatives to Quantum Dots for Intraoperative Near-Infrared Fluorescent Sentinel Lymph Node Mapping by Shunsuke Ohnishi, Stephen J. Lomnes, Rita G. Laurence, Andrew Gogbashian, Giuliano Mariani, John V. Frangioni

“…However, because of concerns over potential toxicity, organic alternatives to QDs will be required for initial clinical studies. …”
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Motion – Cyclo-oxygenase-2 Selective Nonsteroidal Anti-Inflammatory Drugs are as Safe as Placebo for the Stomach: Arguments Against the Motion by Andreas Maetzel

“…Selectivity for the COX-2 isoform affords protection against upper gastrointestinal toxicity possibly at the expense of the cardioprotective effect of traditional NSAIDs. …”
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Carcinogenic and Genotoxicity of some PAHs in commonly consumed smoked fish (<i>Parachanna obscura</i> and <i>Ethmalosa fimbriata) </i> by N.O. Erhunmwunse, S.A. Ekaye

“…Risk assessment conducted using benzo(a)pyrene carcinogenic and mutagenic toxicity equivalent factor (TEQ & MEQ) showed slight to high risk (7.44 x10-5 -1.95 x10-3 ) and exceeded the USEPA guideline (1.0 x 10-5 ) for potential Cancer. …”
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Neonicotinoid Analysis in Sunflower (Helianthus annuus) Honey Samples Collected around Tekirdag in Turkey by Nurullah Ozdemir, Mustafa Necati Muz

“…In recent years, the widespread use of neonicotinoids in agricultural areas has caused environmental pollution due to its lower toxicity to mammals. Honey bees, which are considered as biological indicators of environmental pollution, can carry these pollutants to the hives. …”
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Determination of Heavy Metal Ions and Organic Pollutants in Water Samples Using Ionic Liquids and Ionic Liquid-Modified Sorbents by Minglei Tian, Luwei Fang, Xuemin Yan, Wei Xiao, Kyung Ho Row

“…Several governmental agencies are listing an increasing number of compounds as serious problems in water because of their toxicity, bioaccumulation, and persistence. In recent decades, there has been considerable research on developing analytical methods of heavy metal ions and organic pollutants from water. …”
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Severe Rhabdomyolysis Associated with Acute Amphetamine Toxicosis in a Dog by M. Ryan Smith, Virginie A. Wurlod

“…This case report describes a particularly severe case of rhabdomyolysis associated with amphetamine toxicity and its successful treatment.…”
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Deep phosphoproteomics of Klebsiella pneumoniae reveals HipA-mediated tolerance to ciprofloxacin. by Payal Nashier, Isabell Samp, Marvin Adler, Fiona Ebner, Lisa Thai Lê, Marc Göppel, Carsten Jers, Ivan Mijakovic, Sandra Schwarz, Boris Macek

“…We show that overproduced K. pneumoniae HipA (HipAkp) is toxic to both E. coli and K. pneumoniae and its toxicity can be rescued by overproduction of the antitoxin HipBkp. …”
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