Construction and validation of a predictive model for the risk of myelosuppression after first-line chemotherapy in patients with advanced colorectal cancer by WANG Xuexing, ZHANG Rong, CHU Jie, LIU Zhijin

“…The World Health Organization classification standard for acute and subacute toxicity of anticancer drugs were used as the standards for diagnosing CIM, and the patients were subsequently categorized into CIM and non-CIM groups. …”
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The Role of Polyphenols in Abiotic Stress Tolerance and Their Antioxidant Properties to Scavenge Reactive Oxygen Species and Free Radicals by Muhammad Junaid Rao, Bingsong Zheng

“…We discussed how various abiotic stresses, including heat and chilling stress, drought, salinity, light stress, UV radiation, nanoparticles stress, chemical stress, and heavy metal toxicity, modulate phenylpropanoid metabolism and trigger the accumulation of specific polyphenolic compounds. …”
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Hydrogen sulfide removal from biogas using chemical absorption technique in packed column reactors by M.B. Kulkarni, P.M. Ghanegaonkar

“…The toxicity and corrosion potential of hydrogen sulfide in raw biogas underlines the need for biogas purification. …”
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Enhancing hepatocellular carcinoma therapy with DOX-loaded SiO2 nanoparticles via mTOR-TFEB pathway autophagic flux inhibition by Huanyu Chen, Jun Liu, Zhichao Cao, Jiajia Li, Hong Zhang, Qianqian Yang, Jian Cheng, Yuxian Shen, Kewu He

“…Abstract Chemotherapeutic drugs often fail to provide long-term efficacy due to their lack of specificity and high toxicity. To enhance the biosafety and reduce the side effects of these drugs, various nanocarrier delivery systems have been developed. …”
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Protective Effect of Vitamins C and E on Depot-Medroxyprogesterone Acetate-Induced Ovarian Oxidative Stress In Vivo by Atik Ismiyati, I. Wayan Arsana Wiyasa, Dwi Yuni Nur Hidayati

“…Therefore, this may provide an antioxidant therapy for attenuating the ovarian toxicity found in the DMPA therapy.…”
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Triphenylmethane derivatives have high in vitro and in vivo activity against the main causative agents of cutaneous leishmaniasis. by Renata Celi Carvalho de Souza Pietra, Lucas Fonseca Rodrigues, Eliane Teixeira, Levi Fried, Benjamin Lefkove, Ana Rabello, Jack Arbiser, Lucas Antônio Miranda Ferreira, Ana Paula Fernandes

“…The current standard of care for cutaneous leishmaniasis (CL) is organic antimonial compounds, but the administration of these compounds is complicated by a low therapeutic - toxic index, as well as parenteral administration. …”
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Virtual screening, molecular docking and identification of umami peptides derived from Oncorhynchus mykiss by Wenzhu Zhao, Lijun Su, Shitong Huo, Zhipeng Yu, Jianrong Li, Jingbo Liu

“…Subsequently, water-soluble and toxicity screening were performed by Innovagen and ToxinPred software, respectively. …”
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A Rare Presentation of Checkpoint Inhibitor Induced Distal RTA by Andrew V. Doodnauth, Miriam M. Klar, Zohra R. Malik, Krunal H. Patel, Samy I. McFarlane

“…However, immune-related renal adverse events remain low, representing only a small incidence of reported cases. Common renal toxicity described includes acute interstitial nephritis, minimal change disease, and immune complex glomerulonephritis. …”
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Spinach ameliorates dietary oxidized tallow-induced NAFLD by regulating inflammatory cytokines, peroxisome proliferator-activated receptors, and antioxidant systems by Neelab, Alam Zeb, Muhammad Jamil

“…Purpose: This study aimed to evaluate the ability of Spinacia oleracea dried powder in protecting rabbits from the toxicity caused by oxidized-tallow. Methods: Oxidized tallow and spinach powder were administered to the rabbits. …”
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Gelatin Nanoemulsion-Based Co-Delivery of Terbinafine and Essential Oils for Treatment of <i>Candida albicans</i> Biofilms by Muhammad Aamir Hassan, Sadaf Noor, Jungmi Park, Ahmed Nabawy, Maitri Dedhiya, Robin Patel, Vincent M. Rotello

“…Eugenol and methyl eugenol/terbinafine T-GNEs had an additive efficacy, while carvacrol (CT-GNE) worked synergistically with terbinafine, providing effective antifungal treatment with minimal mammalian cell toxicity. Confocal microscopy demonstrated that CT-GNE penetrated the dense <i>C. albicans</i> biofilm and disrupted the fungal cell membrane. …”
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A Prospective Study Assessing Tumour Response, Survival, and Palliative Care Outcomes in Patients with HIV-Related Kaposi's Sarcoma at Queen Elizabeth Central Hospital, Blantyre, M... by H. Francis, M. J. Bates, L. Kalilani

“…Tumour response, survival, and chemotherapy-related toxicities were documented. Palliative care outcomes were assessed using the African Palliative Care Association (APCA) Palliative Outcome Scale (POS). …”
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Drugs from poisonous plants: Ethnopharmacological relevance to modern perspectives by Bhagya Lakhmi Rajbongshi, Ashis K. Mukherjee

“…While some plants are known for their toxicity, they also contain beneficial phytochemicals that are important for both plants and humans, indicating their dual nature. …”
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Immunoinformatics Identification of B- and T-Cell Epitopes in the RNA-Dependent RNA Polymerase of SARS-CoV-2 by Niti Yashvardhini, Amit Kumar, Deepak Kumar Jha

“…Further, physicochemical properties, allergenicity, toxicity, and stability of RdRp protein were evaluated to demonstrate the specificity of the epitope candidates. …”
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Studies on the biological effects of ozone: 8. Effects on the total antioxidant status and on interleukin-8 production by V. Bocci, G. Valacchi, F. Corradeschi, G. Fanetti

“…While the disinfectant activity of O3 is understandable, it is less clear how other biological effects can be elicited in human blood with practically no toxicity. On the other hand plasma and cells are endowed with a powerful antioxidant system so that a fairly wide range of O3 concentrations between 40 and 80μ g/ml per gram of blood (˜0.83-1.66 mM) are effective but not deleterious. …”
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Computer-Aid System for Automated Jaundice Detection by Ahmad Yaseen Abdulrazzak, Saleem Latif Mohammed, Ali Al-Naji, Javaan Chahl

“…Severe cases of jaundice may cause acute bilirubin encephalopathy due to the toxicity of bilirubin to the cells of the brain, which may lead to kernicterus. …”
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A Standardized Approach to Quantitative Analysis of Nicotine in e-Liquids Based on Peak Purity Criteria Using High-Performance Liquid Chromatography by Vinit V. Gholap, Leon Kosmider, Matthew S. Halquist

“…In contrast to conventional cigarettes which are studied well for their toxicity and health effects, long-term clinical data on e-cigarettes are not available yet. …”
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Urinary BA Indices as Prognostic Biomarkers for Complications Associated with Liver Diseases by Wenkuan Li, Jawaher Abdullah Alamoudi, Nagsen Gautam, Devendra Kumar, Macro Olivera, Yeongjin Gwon, Sandeep Mukgerjee, Yazen Alnouti

“…Hepatobiliary diseases and their complications cause the accumulation of toxic bile acids (BA) in the liver, blood, and other tissues, which may exacerbate the underlying condition and lead to unfavorable prognosis. …”
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Recent Advances in Chitosan-Based Metal Nanocomposites for Wound Healing Applications by Kai Wang, Su Pan, Zhiping Qi, Peng Xia, Haotian Xu, Weijian Kong, Hongru Li, Pan Xue, Xiaoyu Yang, Chuan Fu

“…Chitosan (CS) has been extensively studied as a natural polymer, in the field of wound repair, due to its useful properties, which include a lack of toxicity and stimulation, excellent biological affinity, degradability, and promotion of collagen deposition. …”
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Medicinal plants mediated the green synthesis of silver nanoparticles and their biomedical applications by Haajira Beevi Habeeb Rahuman, Ranjithkumar Dhandapani, Santhoshini Narayanan, Velmurugan Palanivel, Ragul Paramasivam, Ramalakshmi Subbarayalu, Sathiamoorthi Thangavelu, Saravanan Muthupandian

“…Green nano synthesis is a rapidly expanding field of interest in nanotechnology due to its feasibility, low toxicity, eco‐friendly nature, and long‐term viability. …”
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Full Endoscopic Surgery of Bullet Removal of The Spine: A Case Report by Wildan Malik, Nugroho Setyowardoyo

“…Discussion: Surgical intervention is needed for decompression, stabilization, and diminished risks of lead toxicity. The percutaneous endoscopic approach is the least invasive intervention performed to ensure a targeted approach through the anatomical openings of the spine and through intervertebral discs and bone structures, thereby further reducing spinal instability, blood loss, and infection risk. …”
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