Liver Injury Secondary to Anti-TNF-Alpha Therapy in Inflammatory Bowel Disease: A Case Series and Review of the Literature by Ravish Parekh, Nirmal Kaur

“…All TNF-α inhibitors have been associated with liver toxicity, but many of these cases have been reported in patients receiving therapy for rheumatologic disease. …”
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Prevalence and Associated Factors of Malaria Infection among Outpatients Visiting Shewa Robit Health Center, Northcentral Ethiopia by Azene Tesfaye, Tadegew Teshome

“…Interestingly, 73.2% (n = 309) of the participant did not utilize LLINs due to the fear of toxicity (37.4%, n = 158), misconception (21.6%, n = 91), and shortage (14.2%, n = 60). …”
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Status of Soil Acidity under Different Land Use Types and Soil Depths: The Case of Hojje Watershed of Gomibora District, Hadiya Zone, Southern Ethiopia by Tesfaye Abure

“…In the humid regions of Ethiopia, soil productivity and fertility are significantly affected by soil acidity, which is connected to infertility and mineral toxicity. The study aimed to assess the status of soil acidity under different land use types and soil depths in Hojje watershed of Gomibora district, Hadiya Zone, Southern Ethiopia, in November 1, 2020. …”
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Mineral Element Contents in Commercially Valuable Fish Species in Spain by Ana Rivas, Luis Peña-Rivas, Eduardo Ortega, Concepción López-Martínez, Fátima Olea-Serrano, Maria Luisa Lorenzo

“…In conclusion, metal contents in the fish species analyzed are acceptable for human consumption from a nutritional and toxicity point of view.…”
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Sesquiterpene Lactones as Promising Anti-Glioblastoma Drug Candidates Exerting Complex Effects on Glioblastoma Cell Viability and Proneural–Mesenchymal Transition by Andrey V. Markov, Arseny D. Moralev, Kirill V. Odarenko

“…Sesquiterpene triterpenoids (STLs) and their semi-synthetic analogs are considered as a promising source of novel anti-tumor agents due to their low systemic toxicity and multi-target pharmacological effects on key processes associated with tumor progression. …”
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Simultaneous, Dual Continuous Venovenous Haemodiafiltration as Salvage Therapy for Severe Sodium Valproate Intoxication by Aminah Hussan, Ifrah Hasan, Reem El-Hayani, Moustafa Shebl Zahra

“…Sodium valproate overdose leads to CNS depression, cerebral oedema, and severe metabolic acidosis in cases of severe toxicity. Extracorporeal removal, specifically through intermittent haemodialysis, is recommended, though not always tolerated by or accessible to haemodynamically unstable patients in intensive care units. …”
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Effects of Low Concentration of Glyphosate-Based Herbicide on Genotoxic, Oxidative, Inflammatory, and Behavioral Meters in Danio rerio (Teleostei and Cyprinidae) by Eduardo Bortolon Ribas, Gustavo Colombo Dal-Pont, Ariana Centa, Marcos Otávio Bueno, Ricardo Cervini, Rosana Claudio Silva Ogoshi, Claudriana Locatelli

“…The objective of this work was to evaluate the toxicity of a glyphosate-based herbicide (GBH) in zebrafish (Danio rerio). …”
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Comparative Studies on the pH Dependence of DOW of Microcystin-RR and -LR Using LC-MS by Gaodao Liang, Ping Xie, Jun Chen, Ting Yu

“…The difference of hydrophobicity in acidic condition between MC-RR and -LR is important, not only for the analytical method of both toxins, but perhaps also for understanding the difference of toxicity to animals between the two toxins.…”
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Activating PKC-ε induces HIV expression with improved tolerability. by Alivelu M Irrinki, Jasmine Kaur, Bally Randhawa, Ryan McFadden, Chelsea Snyder, Hoa Truong, Daniel Soohoo, Eric Hu, Helen Yu, Bernard P Murray, Bing Lu, Dmytro Kornyeyev, Ishak Darryl Irwan, Lan Nguyen, Yu-San Yang, Jean-Philippe Belzile, Uli Schmitz, Todd C Appleby, Brian Schultz, Jay Lalezari, Steven Deeks, Tomas Cihlar, Jeffrey P Murry

“…However, the clinical utility of PKCs for this application is limited due to toxicity, which is poorly understood. Our studies showed that PKC activation with multiple classes of agonists leads to widespread platelet activation, consistent with disseminated intravascular coagulation, at concentrations that were similar to those required for T-cell activation. …”
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Evaluating the stability and efficacy of fractal-fractional models in reproductive cancer apoptosis with ABT-737 by Kottakkaran Sooppy Nisar, M. Sivashankar, S. Sabarinathan, C. Ravichandran, V. Sivaramakrishnan

“…Conventional cancer therapies, such as chemotherapy and radiation therapy, often encounter issues like toxicity and resistance, primarily due to their inability to effectively differentiate between cancerous and normal cells. …”
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Environmental high temperature (heat stroke) causes articular cartilage damage in vivo and in vitro by Sun yingfei, Yang feng, Ma haoning

“…Therefore, in our current work, we studied the damage of heat toxicity on chondrocytes in vitro. The results showed that heatstroke reduced the cell activity of chondrocytes and triggered a decrease in mitochondrial membrane potential and oxidative stress response. …”
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Biodegradable and Stimuli-Responsive Nanomaterials for Targeted Drug Delivery in Autoimmune Diseases by Nargish Parvin, Sang Woo Joo, Tapas K. Mandal

“…By achieving localized and controlled release of anti-inflammatory and immunosuppressive agents, these systems minimize systemic toxicity and enhance therapeutic efficacy. We discuss the underlying mechanisms of stimuli-responsive nanomaterials, recent applications in treating diseases such as rheumatoid arthritis, multiple sclerosis, and inflammatory bowel disease, and the design considerations essential for clinical translation. …”
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Les pollutions atmosphériques urbaines de proximité à l’heure du Développement Durable by Séverine Frère, Isabelle Roussel, Aymeric Blanchet

“…The measurement of invisible and toxic pollution have remained in a technical domain until recent years, when progressively, atmospheric pollutions have become a politic issue. …”
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Mineralization of Quinoline by BDD Anodes: Variable Effects and Its Effluent Characteristics by C. R. Wang, J. Wang, X. G. Ma, H. Li, S. Z. Zhang

“…The specific oxygen uptake rate was used to assess effluent toxicity, and the value gradually reduced with decreasing effluent organic concentration with mean value of 5.51, 4.19, and 2.20 mgO2 g−1MLSS at electrolysis time of 15, 30, and 45 min, respectively. …”
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In Silico Study of Alkaloids: Neferine and Berbamine Potentially Inhibit the SARS-CoV-2 RNA-Dependent RNA Polymerase by Rishab Marahatha, Asmita Shrestha, Kabita Sharma, Bishnu P. Regmi, Khaga Raj Sharma, Pramod Poudel, Ram Chandra Basnyat, Niranjan Parajuli

“…The QSAR analysis was conducted by using the way2drug/PASS online web resource, and the pharmacokinetics and toxicity properties of these alkaloids were predicted using pkCSM, SwissADME, and ProTox-II webserver. …”
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Quinoline and Quinazoline Alkaloids against COVID-19: An In Silico Multitarget Approach by Esraa M. O. A. Ismail, Shaza W. Shantier, Mona S. Mohammed, Hassan H. Musa, Wadah Osman, Ramzi A. Mothana

“…Among seventy-one tested compounds, twenty-three were selected for molecular docking based on their pharmacokinetic and toxicity profiles. The results identified a number of potential inhibitors. …”
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Authentication of Processed Epimedii folium by EA-IRMS by Fengyan He, Mengyi Li, Yi He, Zhe Dong, Jin Cao, Zhong Dai, Shuangcheng Ma

“…Processing of crude drug is a key character of traditional Chinese medicine (TCM), which could enhance the efficacy and/or reduce the toxicity of crude drugs to fulfill different requirements of TCM clinical practice. …”
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Water Quality of Urban Streams: The Allium cepa Seeds/Seedlings Test as a Tool for Surface Water Monitoring by Camila Gonçalves Athanásio, Daniel Prá, Alexandre Rieger

“…The Pedras stream receives mixed industrial and urban wastewater, while the Lajeado and Preto streams receive wastewater predominantly domestic in nature, which may partially explain the difference in toxicity among the samples. Moreover, the Allium cepa seeds/seedlings were shown to be extremely sensitive in detecting the genotoxicity of environmental water samples and can be applied as the first tool for environmental health hazard identification and prediction.…”
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Vanadate reduction by gram-positive fermentative bacteria isolated from deep-sea sediments on the northern Central Indian Ridge. by Bokyung Kim, Dong Kyun Woo, Juhwan Jeong, Min Sub Sim

“…The oxidation states of vanadium determine its mobility and toxicity, and dissimilatory vanadate reduction has been reported in several microorganisms, highlighting the potential significance of this pathway in the remediation of vanadium contamination and the biogeochemical cycle. …”
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Gastric Mucormycosis in a Renal Transplant Patient Treated with Isavuconazole Monotherapy by Imran Gani, Atbin Doroodchi, Kristina Falkenstrom, Holly Berry, Won Lee, Laura Mulloy, Muhammad Saeed, Rajan Kapoor

“…Our patient was treated with Isavuconazole monotherapy, in an effort to minimize renal toxicity from Amphotericin B to the new allograft. …”
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