Decolorization of mixture of dyes: A critical review by V. K. Gupta, S. Khamparia, I. Tyagi, D. Jaspal, A. Malviya

“…These effluents are recalcitrant to biodegradation and cause acute toxicity to the receiving water bodies, as these comprised of various types of toxic dyes, which are difficult to remove. …”
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Optimization of Green Synthesis of Selenium Nanoparticles and Evaluation of Their Antifungal Activity against Oral Candida albicans Infection by Mohsen Safaei, Hamid Reza Mozaffari, Hedaiat Moradpoor, Mohammad Moslem Imani, Roohollah Sharifi, Amin Golshah

“…Increasing resistance of microbes to available antimicrobial agents has necessitated the production of new compounds with wider activity and lower toxicity. Candida is one of the pathogenic fungal strains that are highly prevalent in oral diseases. …”
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Resolution of Crizotinib-Associated Fulminant Hepatitis following Cessation of Treatment by Gregory W. Charville, Sukhmani K. Padda, Richard K. Sibley, Ajithkumar Puthillath, Paul Y. Kwo

“…Targeted cancer treatments offer the prospect of precise inhibition of tumor growth without the untoward off-target toxicity of traditional chemotherapies. Still, unintended, often idiosyncratic side effects, such as drug-induced liver injury, can occur. …”
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Site-Specific Immunosuppression in Vascularized Composite Allotransplantation: Prospects and Potential by Jonas T. Schnider, Matthias Weinstock, Jan A. Plock, Mario G. Solari, Raman Venkataramanan, Xin Xiao Zheng, Vijay S. Gorantla

“…Investigating the site-specific therapeutic effects and efficacy of systemically active agents may enable optimizing the dosing, frequency, and duration of overall immunosuppression in VCA with minimization or elimination of long-term drug-related toxicity.…”
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Impact Evaluation of Wastewater Treatment Based on the Anaerobic Digestion of Sewage Sludge Using the Life Cycle Assessment Method by Mohammad Rahmati, Majid Rasouli, Hossein Haji Agha Alizadeh, Behnam Ataeiyan

“…Among the 18 effect classes, the treated wastewater in the class of marine environmental toxicity with the amount of 101.1531 kg 1,4-DCB had the most environmental impacts among other classes. …”
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The evolution of antifungal therapy: Traditional agents, current challenges and future perspectives by Cássia Milena de Souza, Bárbara Tavares Bezerra, Daniel Agreda Mellon, Haroldo Cesar de Oliveira

“…The current arsenal of antifungal drugs is limited and often accompanied by high toxicity to patients, elevated treatment costs, increased frequency of resistance rates, and the emergence of naturally resistant species. …”
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Effect of Paraquat on Tilapia Fingerlings under laboratory condition by D.K. Nkeeh, N.A. Jamabo

“…Mortality was measured at different time intervals of 10hr, 12hr, 16hr, 20hr, 46hr and 52hr for the range finding test, using different concentrations of paraquat (120mg/l, 60mgl, 30mg/l and 15mg/l). Acute toxicity test, using different concentrations of paraquat (10mg/l, 5mgl, 2.5mg/l and 1mg/l) was used to measure mortality of 4, 0, 0 and 0 respectively, for 96hrs. …”
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GrB-Fc-KS49, an anti-EMP2 granzyme B fusion protein therapeutic alters immune cell infiltration and suppresses breast cancer growth by Ana Alvarez de Cienfuegos, Lawrence H Cheung, Khalid A Mohamedali, Michael G Rosenblum, Brian Aguirre, Cheng-Hsiang Lu, Anubhav Chandla, Nidhi Kejriwal, Lucia Liu, Ann M Chan, SuYin Kok, Sergio Duarte, David Casero, Madhuri Wadehra

“…The construct’s pharmacokinetics (PK), toxicity profile, and in vivo efficacy were also evaluated.Results GrB-Fc-KS49 exhibited comparable GrB enzymatic activity to commercial GrB, as well as high affinity to an EMP2 peptide, with the dissociation constant in the picomolar range. …”
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Lyophilized and Oven-Dried <i>Manilkara zapota</i> Extracts: Characterization and <i>In Vitro</i>, <i>In Vivo</i>, and <i>In Silico</i> Analyses by María Fernanda Rivas-Gastélum, Patricia Ariadna Galindo-Castillo, Juan Esparza-Sánchez, Miriam Irene Jiménez-Pérez, Yocanxóchitl Perfecto-Avalos, Luis Eduardo Garcia-Amezquita, Diego E. Navarro-López, Edgar R. López-Mena, Eugenio Sánchez-Arreola, Juan Pablo Tamayo-Martínez, Humberto L. Mendoza-Figueroa, María Magdalena Crosby-Galván, Elsa Margarita Crosby-Galván, Jorge L. Mejía-Méndez, Angélica Lizeth Sánchez-López

“…It was noted that the antibacterial and antioxidant activities of extracts were weak due to their MIC (>1000 μg/mL) and IC₅₀ (>2000 μg/mL) values. Still, the toxicity of extracts was poor against <i>Artemia salina</i> nauplii. …”
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A key technology for synergistic backfilling of coal-based solid waste and high-salinity wastewater by Shuning DONG, Shujiang YU, Xingling DONG, Buqin ZHANG, Xiaoming GUO, Xiaodong WANG, Kai WANG, Shibin ZHU, Boqiang WU, Lei LIU

“…The assessment results obtained using Nemerow’s pollution index and extraction toxicity tests indicate that the leachate from the solidified filling paste exhibited a comprehensive pollution index of heavy metals of 0.25, rated as “Safety” according to the grading criteria for comprehensive pollution assessment. …”
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Bevacizumab Demonstrates Prolonged Disease Stabilization in Patients with Heavily Pretreated Metastatic Renal Cell Carcinoma: A Case Series and Review of the Literature by Nicole M. Agostino, Rebecca Gingrich, Joseph J. Drabick

“…These heavily pretreated patients sustained very prolonged periods of stable disease (median of 12 months) with very little toxicity and excellent quality of life. The activity of this agent in patients who had failed prior therapies directed against the VEGFR and mTOR suggests that therapy targeting the ligand, VEGF, is still a viable approach in these patients and deserves further study.…”
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Exploration on the Interaction Ability of Antitumor Compound Bis-[2,6-difluoro-N-(hydroxyl-<κ>O)benzamidato-<κ>O]dibutylitin(IV) with Human Peroxisome Proliferator-Activated Recept... by Jiaqi Mai, Yunlan Li, Xiaozhi Qiao, Xiaoqing Ji, Qingshan Li

“…Diorganotin(IV) antitumor compound bis-[2,6-difluoro-N-(hydroxyl-<κ>O)benzamidato-<κ>O] (DBDF2,6T) was one of the novel patent organotin compounds with high antitumor activity and relatively low toxicity. In this study, several methods were used to study the interaction between DBDF2,6T and hPPARγ protein, including fluorescence quenching, three-dimensional (3D) fluorescence, drug affinity responsive target stability (DARTS), ultrafiltration-LC, and molecular docking. …”
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Association between air pollution and osteoporosis: A systematic review by Prabowo Nurhasan Agung, Soetrisno, Nurwati Ida, Ardyanto Tonang Dwi, Poncorini Eti, Nurudhin Arief, Dirgahayu Paramasari

“…These mechanisms include oxidative stress, systemic inflammation, and heavy metal toxicity in women disproportionately, older adults and urban populations. …”
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Role of Copper and Zinc Ions in the Hydrolytic Degradation of Neurodegeneration-Related Peptides by Valentina Pirota, Enrico Monzani, Simone Dell’Acqua, Chiara Bacchella

“…Spontaneous cleavage reactions normally occur in vivo on amino acid peptide backbones, leading to fragmentation products that can have different physiological roles and toxicity, particularly when the substrate of the hydrolytic processes are neuronal peptides and proteins highly related to neurodegeneration. …”
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Bio-Tribocorrosion of Titanium Dental Implants and Its Toxicological Implications: A Scoping Review by Sumit Gaur, Rupali Agnihotri, Sacharia Albin

“…However, further validation of the role of bio-tribocorrosion on the durability of the Ti dental implants and Ti toxicity is warranted through clinical trials.…”
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The “Trojan Horse” Approach to Tumor Immunotherapy: Targeting the Tumor Microenvironment by Delia Nelson, Scott Fisher, Bruce Robinson

“…The “Trojan Horse” approach of intratumoural delivery aims to promote immune-mediated destruction by inducing microenvironmental changes within the tumour at the same time as avoiding the systemic toxicity that is often associated with more “full frontal” treatments such as transfer of large numbers of laboratory-expanded tumor-specific cytotoxic T lymphocytes or large intravenous doses of cytokine. …”
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DISTRIBUTION AND POTENTIAL OF CAMELLIA SPP. IN THE CENTRAL HIGHLANDS, VIETNAM, FOR DEVELOPING HIGH-VALUE PRODUCTS IN THE FOOD INDUSTRY by Thi Thang Long Nguyen, Vu Mai Quynh Luong

“…Camellia extract does not cause acute toxicity and has a blood sugar-lowering effect. Vietnam has much experience growing green tea; the total green tea growing area is 131,200 hectares. …”
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Advances in Illuminating Prostate Cancer with Emerging Phototherapies by Ali Usman

“…Functionalized nanoparticles, such as those targeting prostate-specific membrane antigen (PSMA), enhance the precision of therapeutic delivery, reducing systemic toxicity. Combination strategies incorporating PDT and PTT with conventional modalities, including surgery, chemotherapy and immunotherapy, have demonstrated synergistic effects, leading to better therapy sensitization. …”
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PEGylated Cisplatin Nanoparticles for Treating Colorectal Cancer in a pH-Responsive Manner by Wei Li, Yongjun Sun, Jian Chen, Zhibin Jiang, Jinbao Yang

“…Cisplatin cannot target CRC cells and has notable toxicity, which significantly limits its clinical application. …”
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Monosodium glutamate (MSG) exposure induced oxidative stress and disrupted testicular hormonal regulation, exacerbating reproductive dysfunction in male WISTAR rats by Adesua Emmanuel Ogunmokunwa, Babatunde Oluwaseun Ibitoye

“…Background: Monosodium glutamate (MSG) is a common food additive linked to various health concerns, including potential reproductive toxicity. Objective: To investigate the effects of chronic, low-dose MSG on testicular hormones and oxidative stress biomarkers in adult male Wistar rats. …”
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