On the Environmental Factors Affecting the Structural and Cytotoxic Properties of IAPP Peptides by Marianna Flora Tomasello, Alessandro Sinopoli, Giuseppe Pappalardo

“…Other open questions are related to the nature of the IAPP toxic species and how exactly β-cells die. …”
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Spatial control of doping in conducting polymers enables complementary, conformable, implantable internal ion-gated organic electrochemical transistors by Duncan J. Wisniewski, Liang Ma, Onni J. Rauhala, Claudia Cea, Zifang Zhao, Alexander Ranschaert, Jennifer N. Gelinas, Dion Khodagholy

“…Organic electronics offer biocompatibility and conformability; however, generation of complementary organic transistors requires introduction of separate materials with inadequate stability and potential for tissue toxicity, limiting their use in biomedical applications. …”
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PK/PD-Guided Strategies for Appropriate Antibiotic Use in the Era of Antimicrobial Resistance by Tetsushu Onita, Noriyuki Ishihara, Takahisa Yano

“…First, we discuss the importance of drug concentration management for enhancing efficacy while preventing toxicity, considering various patient populations, including pediatric and elderly patients with their unique physiological characteristics. …”
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“I’m Seeing Dead People”: A Case Report on Salicylate Poisoning in a Patient with Hallucinations by Jessica Meyers, Sean McCormick, Phillip D. Levy, Michael J. Twiner

“…Conclusion: This case serves as a reminder for physicians to have a high index of suspicion for chronic toxicities including salicylates in patients who present as acute psychosis or altered mental status of unknown etiology.…”
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The Evaluation of Impact of Cable Power Lines on the Environment by M. A. Korotkevich, S. N. Azarov

“…To evaluate the environmental impact of electrical cable materials, an approach has been developed that takes into account not only the toxicity of the materials but also their volumetric content in the cable. …”
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Exploring the effects of perfluorooctanoic acid (PFOA) and tetrabromobisphenol A (TBBP-A) on silkworm from the insights of metabolome by Xing Zhang, Yifei Kong, Zihan He, Wenbin Yu, Wenjing Shao, Chengliang Gong, Wenlin Zhou, Xiaolong Hu

“…These findings suggest that PFOA and TBBP-A disrupt crucial metabolic processes in silkworms, indicating potential toxicity and prompting further investigation into their effects on human health and the environment. …”
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Immunotherapy for Metastatic Melanoma with Right Atrial Involvement in a Patient with Rheumatoid Arthritis by Zachary Benson, Sarah Gordon, Patricia Nicolato, Andrew Poklepovic

“…Furthermore, some patients with preexisting autoimmune disease may be safely treated with checkpoint inhibition therapy, and patients with a severe immune toxicity from one class may successfully be treated with an alternate class.…”
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Serotonin circuits act cooperatively with pathophysiology of opioid use disorder by Arakawa Hiroyuki, Ozawa Akihiko

“…We interrogate the potential neural roles of 5-HT in OUD-related symptoms including 5-HT toxicity and pathophysiology and discuss potential availability of 5-HT-related agents as a neuromodulatory therapeutic interacting with opioid mediated neural mechanisms and the OUD-related symptoms.…”
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Insulin Blocks Glutamate-Induced Neurotoxicity in Differentiated SH-SY5Y Neuronal Cells by Madhavan Nampoothiri, Neetinkumar D. Reddy, Jessy John, Nitesh Kumar, Gopalan Kutty Nampurath, Mallikarjuna Rao Chamallamudi

“…Thus, we examined the neuroprotective effect of insulin on glutamate-induced toxicity on differentiated SH-SY5Y neuronal cells. …”
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Allelopathic Potential of Lantana camara L. Leaf Extracts and Soils Invaded by It on the Growth Performance of Lepidium sativum L. by Likyelesh Gebreyohannes, Meseret C. Egigu, M. Manikandan, J. M. Sasikumar

“…In the current study, phytotoxicity of hexane and ethanolic leaf extracts of L. camara in different concentrations and soils invaded by it on Lepidium sativum were investigated under laboratory conditions. Soil toxicity was evaluated by comparing the growth of L. sativum on soils sampled from Lantana-invaded and Lantana-free sites. …”
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Effect of Paraquat on Tilapia Fingerlings under laboratory condition by D.K. Nkeeh, N.A. Jamabo

“…Mortality was measured at different time intervals of 10hr, 12hr, 16hr, 20hr, 46hr and 52hr for the range finding test, using different concentrations of paraquat (120mg/l, 60mgl, 30mg/l and 15mg/l). Acute toxicity test, using different concentrations of paraquat (10mg/l, 5mgl, 2.5mg/l and 1mg/l) was used to measure mortality of 4, 0, 0 and 0 respectively, for 96hrs. …”
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In vitro antioxidant capacity and free radical scavenging evaluation of standardized extract of Costus afer leaf by T.G. Atere, O.A. Akinloye, R.N. Ugbaja, D.A. Ojo, G. Dealtry

“…Keywords: Costus afer, Antioxidant, Toxicity…”
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Massive Acetaminophen Overdose Treated Successfully with N-Acetylcysteine, Fomepizole, and Hemodialysis by Michael H. Chiu, Natalia Jaworska, Nicholas L. Li, Mark Yarema

“…There is strong evidence for N-acetylcysteine (NAC) as a safe and effective antidote for acetaminophen toxicity. However, there is less clarity in the management of massive overdoses (acute, single ingestions>500 mg/kg with 4-hour equivalent concentrations ~6000 μmol/L) which are often associated with metabolic acidosis and multiorgan dysfunction. …”
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Co(II) Complex of Mefloquine Hydrochloride: Synthesis, Antimicrobial Potential, Antimalaria and Toxicological Activities by Adediji J. Femi, Obaleye J. Ayoola

“…Overall, it was revealed that both mefloquine and its metal complex do not showed toxicity particularly on the liver and kidney.…”
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Stable and inert manganese complexes for magnetic resonance imaging by Ndiaye, Daouda, Tóth, Éva

“…Manganese is an essential metal which alleviates its potential toxicity and the environmental concerns related to the use of Gd$^{3+}$. …”
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Ethylene Glycol Poisoning: An Unusual Cause of Altered Mental Status and the Lessons Learned from Management of the Disease in the Acute Setting by R. Singh, E. Arain, A. Buth, J. Kado, A. Soubani, N. Imran

“…Ethylene glycol is found in many household products and is a common toxic ingestion. Acute ingestions present with altered sensorium and an osmolal gap. …”
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Heavy Metal Stress and Some Mechanisms of Plant Defense Response by Abolghassem Emamverdian, Yulong Ding, Farzad Mokhberdoran, Yinfeng Xie

“…Unprecedented bioaccumulation and biomagnification of heavy metals (HMs) in the environment have become a dilemma for all living organisms including plants. HMs at toxic levels have the capability to interact with several vital cellular biomolecules such as nuclear proteins and DNA, leading to excessive augmentation of reactive oxygen species (ROS). …”
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Recycling of Oily Sludge as a Roadbed Material Utilizing Phosphogypsum-Based Cementitious Materials by Wei Xiao, Xiao Yao, Fuyang Zhang

“…The efficacy of the S/S process is assessed mainly through an unconfined compressive strength (UCS) test and a toxicity leaching test. Road performance, including water stability, freeze-thaw resistance, and volume stability, is also tested on the solidified samples. …”
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Nanoparticles Modulating the Immune Microenvironment in Breast Cancer Treatment by Guo LJ, Wu J, Lu W, Li J, Wang Y, Yang H, Wang TZ

“…The review addresses the challenges in clinical translation, focusing on safety, biocompatibility, and toxicity. Finally, we outline future research directions and the potential advancements in nanoparticle-based immunotherapy, emphasizing their transformative impact on breast cancer treatment.Keywords: nanoparticle, breast cancer, immune cells…”
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Natural products as part of triple negative breast cancer by Yozlem Kobakova, Maria Moneva-Sakelarieva, Spiro Konstantinov, Georgi Momekov, Stefka Achkova Ivanova, Ventseslava Atanasova, Maria Chaneva, Radoslav Tododrov, Nikolay Bashev, Petar Atanasov

“…Immunotherapy causes a wide variety of toxic effects called immune-related adverse events (IRAEs). …”
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