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1561
Whole genome sequence of Streptomyces colonosanans strain MUSC 93JT isolated from mangrove forest in Malaysia
Published 2020-03-01“…Displaying selective toxicity that kills only cancer cells, ectoine has showed its potential to be developed as therapeutic agents for humans. …”
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1562
In Vitro Susceptibility of Canine Influenza A (H3N8) Virus to Nitazoxanide and Tizoxanide
Published 2010-01-01“…These results suggest that NTZ and TIZ are effective against CIV and may be useful for treatment of canine influenza in dogs but further investigation of the in vivo efficacy against CIV as well as the drug's potential for toxicity in dogs is needed.…”
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1563
Current Status of Human Adipose–Derived Stem Cells: Differentiation into Hepatocyte-Like Cells
Published 2011-01-01“…In this review, we will not only present recent data regarding hASC biology, their isolation, and differentiation capability towards hepatocytes, but also the potential application of hASC-derived hepatocytes to study drug toxicity. Additionally, this review will discuss the therapeutic potential of hASCs as undifferentiated cells in liver regeneration.…”
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1564
Investigation on Smoke Suppression Mechanism of Hydrated Lime in Asphalt Combustion
Published 2018-01-01“…In addition, hydrated lime is alkaline and can thus neutralize acidic gases such as SO2 and reduce the toxicity of gaseous products. With the addition of 40 wt.% hydrated lime, the total smoke release and the CO release rate both decrease by more than 20% relative to the addition of the same amount of limestone fillers and decrease by more than 10% relative to the addition of the same amount of magnesium hydroxide flame retardant.…”
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1565
Analgesic, Anti-Inflammatory, and GC-MS Studies on Castanospermum australe A. Cunn. & C. Fraser ex Hook.
Published 2014-01-01“…The analgesic activity was analyzed by hot plate method and acetic acid-induced writhing test whereas anti-inflammatory study was done by carrageenan induced paw oedema model. The acute toxicity study revealed that ethanol extracts of leaf and bark of C. australe were safe even at a higher dose of 2000 mg/kg whereas ethanol extract of seed was toxic at the same dose. …”
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1566
The Exploitation of Nanotechnology in Herbicides and Bioherbicides: A Novel Approach for Sustainable Weed Management
Published 2025-01-01“…However, further research is still required to assess their effectiveness under natural conditions, improve their stability over time and study their bioaccumulation and toxicity toward non-target organisms.…”
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1567
Chiral recognition of some D and L-amino acids by microcrystalline cellulose assisted diffusion-ordered NMR spectroscopy
Published 2025-03-01“…Microcrystalline cellulose has been gradually gained more and more interest owing to its wide compatibility, surface area, excellent separation efficiency, non-toxicity, cost-effective, and mechanical stability in many fields. …”
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1568
Iron Chelators in Treatment of Iron Overload
Published 2022-01-01“…Although iron is a crucial element for life, iron overload can be potentially toxic for human cells due to its role in generating free radicals. …”
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1569
H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy
Published 2010-01-01“…In general, analysis of γH2AX expression can be used to detect the genotoxic effect of different toxic substances. When applied to clinical samples from cancer patients, evaluation of γH2AX levels may allow not only to monitor the efficiency of anticancer treatment but also to predict of tumor cell sensitivity to DNA damaging anticancer agents and toxicity of anticancer treatment toward normal cells.…”
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1570
Nutrient Management for Soybean Crops
Published 2021-01-01“…Nutrient requirements for soybean crops vary in concentration, and deviations can cause nutrient deficiency or toxicity in soybean crops. Nutrient availability to soybean crops depends on the available nutrients in the soil solution, the form of available soil nutrients, mode of uptake of nutrients, its interaction with other soil nutrients, soil chemistry, and method of fertilizer application. …”
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1571
Improving paraffin precipitate inhibition using glycine and Palm-based Methyl Ester Sulfonate (MES) eco-friendly inhibitors.
Published 2025-01-01“…However, traditional chemical inhibitors present problems due to their high toxicity and low biodegradability, leading to increased operational costs and environmental concerns. …”
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1572
Study on the Properties of Polyurethane–Urea Elastomers Prepared by TDI/MDI Mixture
Published 2024-01-01“…Hence, 4,4′-diphenylmethane diisocyanate (MDI), an isocyanate with significantly lower toxicity compared to TDI, was used as a partial substitute for TDI to prepare PUU through the prepolymerization method with other raw materials including polytetramethylene glycol (PTMG) and 4,4′-methylene-bis(2-chloroaniline) (MOCA) in this paper. …”
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1573
Phase Change Materials in Metal Casting Processes: A Critical Review and Future Possibilities
Published 2022-01-01“…Despite having advantages, inorganic PCM comes with major disadvantages, that is, toxicity, corrosivity, supercooling, and low thermal expansion. …”
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1574
Comparative Evaluation of the Antidiabetic Effects of Different Parts of Cassia fistula Linn, a Southeast Asian Plant
Published 2013-01-01“…The hypoglycemic effect of the methanolic and aqueous extracts of whole parts of Cassia fistula in both normoglycemic and streptozotocin-nictotinamide induced Type 2 diabetic rats were investigated. Acute toxicity, oral glucose tolerance test and glucose uptake in isolated rat hemidiaphragm were performed in normal rats. …”
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1575
Growth, Water Relations, and Photosynthetic Activity Are Associated with Evaluating Salinity Stress Tolerance of Wheat Cultivars
Published 2020-01-01“…The wheat cultivars were otherwise exposed to anatomical characteristics and photosynthetic gas exchange investigations. NaCl toxicity induced a noticeable reduction in stomatal aperture area (SAA), stomatal conductance (Gs), transpiration rate (Tr), and leaf net photosynthetic rate (Pn). …”
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1576
Recent advances in small molecule LpxC inhibitors against gram-negative bacteria (2014–2024)
Published 2025-02-01“…This paper mainly focuses on the structure optimization, conformational relationship and animal toxicity of small molecule LpxC inhibitors over the past 10 years, especially in the last 5 years, in order to provide ideas for the development and clinical research of LpxC inhibitors.…”
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1577
International Normalized Ratio (INR) Increases amongst Two Patients Living with HIV on Warfarin after Being Switched from a Nevirapine to a Dolutegravir-Based Antiretroviral Regime...
Published 2021-01-01“…Upon discontinuing nevirapine, close monitoring of drugs with narrow therapeutic indices is paramount since dosing requirements may significantly reduce, increasing the probability of toxicity development. We present two cases describing interactions experienced by patients living with HIV, while transitioning from nevirapine to dolutegravir-based HIV regimens. …”
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1578
The Role of Insulin, Insulin Growth Factor, and Insulin-Degrading Enzyme in Brain Aging and Alzheimer's Disease
Published 2005-01-01“…Such a decrease involves the insulin receptor cascade and can also increase amyloid toxicity. Insulin and IGF-I may modulate brain levels of insulin degrading enzyme, which would also lead to an accumulation of Aβ amyloid.…”
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1579
Modeling and optimal regulation of erythropoiesis subject to benzene intoxication
Published 2004-02-01“…The exposure-dose-response relationship of benzene in humans is expected to be nonlinear becausebenzene undergoes a series of metabolic transformations, detoxifying and activating, resulting in various metabolites that exert toxic effects on the bonemarrow.   Since benzene is a known human leukemogen, the toxicity of benzene in thebone marrow is of most importance. …”
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1580
Evaluating Traditional Chinese Medicine and Herbal Products for the Treatment of Gestational Diabetes Mellitus
Published 2019-01-01“…None of the herbal medicine and products examined reported toxicity in the experimental models. Overall, treatments of gestational diabetes by western or alternative interventions are grossly understudied. …”
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