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1501
Water-Soluble Vitamins: Hypo- and Hypervitaminosis in Pediatric Population
Published 2025-01-01“…Conversely, although uncommon, excessive intake of certain water-soluble vitamins may cause mild toxicity, primarily gastrointestinal or neurological. …”
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1502
Comprehensive analysis of histophysiology, transcriptomics and metabolomics in goslings exposed to gossypol acetate: unraveling hepatotoxic mechanisms
Published 2025-01-01“…Although the general toxicity of free gossypol is well-known, its specific effects on the liver—the primary site where it accumulates—are less thoroughly studied, particularly at the molecular level. …”
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1503
Facile Synthesis, Characterization, and Cytotoxic Activity of Europium-Doped Nanohydroxyapatite
Published 2016-01-01“…Also, impregnation and release of 5-fluorouracil were assessed in PBS. The toxicity effects of all samples were studied using viability assays on human fibroblasts cells (HGF-1) in vitro. …”
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1504
Metronomic Cyclophosphamide and Methotrexate Chemotherapy Combined with 1E10 Anti-Idiotype Vaccine in Metastatic Breast Cancer
Published 2011-01-01“…The median duration of the response (CR+PR+SD) was 18,43 months (12,20–24,10 months), being higher than 12 months in 76,9% of the patients. Overall toxicity was generally mild. Metronomic chemotherapy combined with 1E10-Alum vaccine immunotherapy might be a useful therapeutic option for the treatment of metastatic breast cancer due to its potential impact on survival and patient quality of live, low toxicity and advantages of the administration.…”
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1505
Restricted Use Pesticides for Use in Florida
Published 2019-09-01“…All pesticides are classified according to their toxicity, use pattern, and environmental effects. The two main classifications are unclassified use and restricted use, though unclassified pesticides are commonly referred to as general use pesticides. …”
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1506
Acute diquat poisoning induces paralytic ileus and hepatic portal venous gas: a case report
Published 2025-02-01“…Diquat is a non-selective, broad-spectrum herbicide. Although its toxicity is significantly lower than paraquat, it still has a high mortality rate when ingested in large quantities. …”
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1507
Therapeutic Drug Monitoring in the Treatment of Active Tuberculosis
Published 2011-01-01“…Therapeutic drug monitoring ensures optimal dosing while aiming to reduce toxicity. However, due to the high costs and complexity of testing, therapeutic drug monitoring is not routinely used in the treatment of individuals with active tuberculosis, despite the efficacy demonstrated in several randomized trials. …”
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1508
Pesticide Application Best Management Practices for the Citrus Grove Worker
Published 2009-05-01“…It provides information for citrus grove workers about pests, pest control methods, pesticide toxicity, how to transport pesticides, first aid and decontamination, preventing exposure, worker protection standard, storage and disposal, pre-operation checkpoints, mixing and loading, container management, calibration, and application best management practices. …”
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1509
An overview of structurally diversified anticonvulsant agents
Published 2019-09-01“…The quest for new antiepileptic molecules with more specificity and less CNS toxicity continues for medicinal chemists until a new and ideal drug arrives. …”
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1510
Adsorption of Bovine Serum and Bovine Haemoglobin onto Chitosan Film
Published 2012-09-01“…The application of chitosan as a dressing material for burns presents advantages such as bacteriostatic and fungistatic activity, low toxicity and biocompatibility. In this work, the barrier properties and mechanical strength of chitosan were evaluated for subsequent use as a dressing material. …”
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1511
Creeping Indigo, A Poisonous Plant of Concern in Florida Pastures
Published 2015-11-01“… A recent rise in suspected horse poisonings has brought new attention to creeping indigo (Indigofera spicata), a toxic plant which has reportedly been in Florida for as long as 90 years. …”
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1512
Restricted Use Pesticides for Use in Florida
Published 2019-09-01“…All pesticides are classified according to their toxicity, use pattern, and environmental effects. The two main classifications are unclassified use and restricted use, though unclassified pesticides are commonly referred to as general use pesticides. …”
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1513
Severe pulmonary-renal syndrome in honeybee sting envenomation – A case report
Published 2022-09-01“…Honeybee stings with features of envenomation (either local or allergic and rarely systemic toxicity) are often seen in agriculture workers. An initial presentation with severe diffuse alveolar hemorrhage or pulmonary-renal syndrome is rare and only confined to a few case reports. …”
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1514
Severe Acute Radiation Dermatitis in a Patient with Argyria
Published 2014-01-01“…Acute radiation dermatitis (RD) is an expected toxicity in patients undergoing radiotherapy but it is unknown to what extent argyria affects the onset and severity of RD. …”
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1515
Hypofractionated External-Beam Radiotherapy for Prostate Cancer
Published 2013-01-01“…The preliminary results from clinical studies indicate that abbreviated fractionation programs can result in successful treatment of localized prostate cancer without escalation of late toxicity.…”
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1516
A Review of the Mechanism of Injury and Treatment Approaches for Illness Resulting from Exposure to Water-Damaged Buildings, Mold, and Mycotoxins
Published 2013-01-01“…Mechanisms of illness include inflammation, oxidative stress, toxicity, infection, allergy, and irritant effects of exposure. …”
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1517
Case report: A case of severe lower limb necrotizing fasciitis caused by an insulin injection has been reported
Published 2025-01-01“…Necrotizing fasciitis (NF) is a rare but life-threatening soft tissue infection, often accompanied by severe systemic toxicity. Early detection and prompt treatment are critical for survival. …”
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1518
HSV-1 Encephalitis in an Elderly Man Receiving Ibrutinib for Waldenstrom’s Macroglobulinemia
Published 2020-01-01“…Though ibrutinib has proven to be a revolutionary new small molecule agent, and has relatively minimal toxicity as compared to traditional chemotherapy, infections have emerged as a major complication of therapy. …”
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1519
La Flora Común es la Flora Medicinal
Published 2021-12-01“…The system is public and merits study by anthropologists, ethnobotanists, students of ethnomedicine, and laboratory analysis, always in close collaboration with the Mayan communities, with regard to methods of preparation and administration, bioactivity, toxicity, and quality control.…”
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1520
Clinical Experience with Tixocortol Pivalate
Published 1988-01-01“…Tixocortol pivalate, the 21-thiol derivative of hydrocortisone. is a newly synthesized steroid with topical anti-inflammatory properties but is devoid of systemic glucocorticoid and mineralocorticoid activities and toxicity. The mechanism of action appears to be similar to that of other corticosteroids with regard to steroid binding sites and prostaglandin biosynthesis, however. the disassociation between local and systemic effects is due to a 'first pass' liver metabolism and rapid transformation with in red blood cells. ln both open and controlled studies in patients with acute or recurrent distal colitis, clinical efficacy has been noted at doses of 250 mg to 1000 mg in 100 ml solution without an effect on scrum cortisol levels or blood chemistries. …”
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