Pituranthos chloranthus Oil as an Antioxidant-Based Adjuvant Therapy against Cisplatin-Induced Nephrotoxicity by Aida Lahmar, Zaineb Dhaouefi, Rihab Khlifi, Fairouz Sioud, Leila Chekir- Ghedira

“…Significant mitigation of cisplatin-induced toxicity was confirmed by lowered levels of serum biomarkers and reduced DNA damage in liver and kidney. …”
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Causal Relationship Between Emotional Disorders and Thyroid Disorders: A Bidirectional Two‐Sample Mendelian Randomization Study by Jiaying Fan, Kai Zhou, Cuiwen Yu

“…Results IVW results showed negative causal relationships between bidirectional emotional disorders and hypothyroidism, toxic single thyroid nodules in thyrotoxicosis, and hyperthyroidism/toxicity. …”
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Cytotoxic effect of 1% and 3% Sodium hypochlorite as irrigation agent in primary teeth on human red blood cells: an in vitro study by Divya Mukundan, Maria Anthonet Sruthi

“…According to the current study's findings, 1% sodium hypochlorite solution exhibited less toxicity than 3% sodium hypochlorite.…”
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Mini review of plant products as food supplement against MSG-induced liver injury: antioxidant, oxidative stress and histological prospects by Dwi Pratiwi Kasmara, Erlina Abdullah, Zaliha Harun, Fatmi Nirmala Sari, Norhashima Abd Rashid, Seong Lin Teoh

“…By compiling this evidence, this review provides insights into their potential as preventive strategies against MSG-related liver toxicity, supporting their inclusion in dietary regimens for the maintenance of liver function.…”
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Dextran-Polyacrylamide as Matrices for Creation of Anticancer Nanocomposite by G. Telegeev, N. Kutsevol, V. Chumachenko, A. Naumenko, P. Telegeeva, S. Filipchenko, Yu. Harahuts

“…Controlled targeting at the site of action and reduced time of exposure of nontargeted tissues increase the efficacy of the treatment and reduce toxicity and side effects, improving compliance and convenience. …”
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Characterizations of Size-segregated Ultrafine Particles in Diesel Exhaust by Jaehyun Lim, Cheolsoo Lim, Sungwoon Jung

“…Two significant size ranges of toxicity equivalent quantity peaks in the ultrafine (34–66 nm) and accumulation (170–330 nm) modes were observed for the size-segregated DEPs. …”
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Manganese Neurotoxicity as a Complication of Chronic Total Parenteral Nutrition by Alisha Khan, Jonathan Hingre, Amit S. Dhamoon

“…One of the more rare complications of TPN use is manganese toxicity. We provided care for a 38-year-old female on chronic TPN who presented to the hospital with Parkinsonian features, confusion, falls, and lethargy. …”
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Antimalarial, Antioxidant, and Toxicological Evaluation of Extracts of Celtis africana, Grosseria vignei, Physalis micrantha, and Stachytarpheta angustifolia by Michael Konney Laryea, Lawrence Sheringham Borquaye

“…The phosphomolybdenum and DPPH (1, 1-diphenyl-2 picrylhydrazyl) assays were used to evaluate antioxidant activities while toxicity assessment was carried out in mice using the acute toxicity test and kidney and liver function tests. …”
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Preparation of Ca-Mg Double-Doped Mesoporous Silica Nanoparticles and Their Drug-Loading and Drug-Releasing Properties by Qian Zhang, Jiamin Huang, Chao Liu, Ruihua Chen, Tao Jiang, Yusufu Hailili, Telieke Bahetibieke, Xiaohui Tang, Mei Wang

“…Therefore, developing low-toxicity MSNs with good biocompatibility, biodegradability, and rapid release at the tumor site is a key scientific issue to be addressed. …”
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Phytochemical Screening and In Vivo Antimalarial Activity of Two Traditionally Used Medicinal Plants of Afar Region, Ethiopia, against Plasmodium berghei in Swiss Albino Mice by Sibhatu Gebrehiwot, Mohammed Shumbahri, Amelework Eyado, Tilahun Yohannes

“…All extracts revealed no obvious acute toxicities on mice up to the highest (5000mg/kg) dose given. …”
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Biochemical and histopathological profiling of Wistar rat treated with Brassica napus as a supplementary feed by Kazi Md. Mahmudul Hasan, Nasrin Tamanna, Md. Anwarul Haque

“…Noticeable tissue injury observed in this study is a sign of the relative toxicity of erucic acid containing rapeseed oil to mammalian species. …”
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A CDFT-Based Computational Peptidology (CDFT-CP) Study of the Chemical Reactivity and Bioactivity of the Marine-Derived Alternaramide Cyclopentadepsipeptide by Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik

“…The ADMET indices confirm this assertion through the absence of toxicity and good absorption and distribution properties.…”
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Safety evaluation of the food enzyme protein‐glutamine γ‐glutamyltransferase from the non‐genetically modified Streptomyces mobaraensis strain AE‐BTG by EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Monika Sramkova, Henk Van Loveren, Laurence Vernis, Jaime Aguilera, Magdalena Andryszkiewicz, Natalia Kovalkovicova, Giulio diPiazza, Yi Liu

“…Genotoxicity tests did not indicate a safety concern. The systemic toxicity was assessed by means of a repeated dose 90‐day oral toxicity study in rats. …”
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Exploring the microbiome-gut-testis axis in testicular germ cell tumors by Sona Ciernikova, Aneta Sevcikova, Michal Mego

“…This review explores the emerging role of the microbiome-gut-testis axis in the context of testicular cancer, highlighting its implications for disease onset, progression, treatment efficacy, and toxicity. Identifying potential microbial biomarkers, followed by microbiota modulation to restore a balanced microbial community, might offer a novel supportive strategy for improving treatment efficacy in refractory TGCT patients while reducing chemotherapy-induced toxicity. …”
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Assessment of cytotoxicity of clear aligners coated with zinc oxide nanoparticles by Indu Ravi, Vignesh Kailasam

“…An increase in particle size demonstrated lesser cytotoxicity. ,.Zinc oxide coated aligners should be used with caution after day 7 even though there is only slight toxicity.…”
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Detecting Methotrexate in Pediatric Patients Using Artificial Neural Networks by Alejandro Medina Santiago, Jorge Iván Bermúdez Rodríguez, Jorge Antonio Orozco Torres, Julio Alberto Guzmán Rabasa, José Manuel Villegas Izaguirre, Gladys Falconi Alejandro

“…However, there is evidence of an association between methotrexate and toxicity risks, which influences the personalization of treatment, particularly in the case of childhood ALL. …”
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Systemic and Nonrenal Adverse Effects Occurring in Renal Transplant Patients Treated with mTOR Inhibitors by Gianluigi Zaza, Paola Tomei, Paolo Ria, Simona Granata, Luigino Boschiero, Antonio Lupo

“…In particular, mTOR-I may induce systemic nonnephrological side effects including pulmonary toxicity, hematological disorders, dysmetabolism, lymphedema, stomatitis, cutaneous adverse effects, and fertility/gonadic toxicity. …”
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Antimalarial Activity of Tinospora baenzigeri against Plasmodium berghei-Infected Mice by Sakaewan Ounjaijean, Manas Kotepui, Voravuth Somsak

“…It was found that the aqueous crude extract of T. baenzigeri stem did not exhibit any sign of toxicity up to the dose of 2,000 mg/kg. The extract significantly (P<0.01) inhibited parasitemia in a dose-dependent manner, with 22.02%, 50.81%, and 74.95% inhibition. …”
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Liver-targeting iron oxide nanoparticles and their complexes with plant extracts for biocompatibility by Shushanik A. Kazaryan, Seda A. Oganian, Gayane S. Vardanyan, Anatolie S. Sidorenko, Ashkhen A. Hovhannisyan

“…Thanks to their simple synthesis, controlled physical properties, and minimal toxicity, iron oxide nanoparticles (Fe3O4 NPs) are widely used in many biomedical applications (e.g., bioimaging, drug delivery, biosensors, diagnostics, and theranostics). …”
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Evaluation on Genotoxicity and Teratogenicity of Aqueous Extract from Cyclocarya paliurus Leaves by Lihong Deng, Jiandu Lei, Jing He, Jing Liu, Luying Wang, Rui Zhang, Xinhua Liu, Yun Liu

“…In this study, we have conducted the genotoxicity assay (including Ames test, bone marrow polychromatic erythrocyte micronucleus test, and sperm abnormality test in mice) and traditional teratogenicity assay in rats (maternal toxicity, embryo toxicity, and teratogenicity test) to assess the genetic and teratogenic safety of aqueous extracts from C. paliurus leaves. …”
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