Protective Role of Catechin and Quercetin in Sodium Benzoate-Induced Lipid Peroxidation and the Antioxidant System in Human Erythrocytes In Vitro by Gamze Yetuk, Dilek Pandir, Hatice Bas

“…Catechin or quercetin protected the erythrocytes against SB-induced toxicity only at low concentrations of SB. The presence of catechin or quercetin at 10 μM have no effect on SB-induced toxicity at high concentrations of SB (50 and 100 μg/mL). …”
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αSynuclein and Mitochondrial Dysfunction: A Pathogenic Partnership in Parkinson’s Disease? by David Protter, Charmaine Lang, Antony A. Cooper

“…Amplifying cycles of mitochondrial dysfunction and αSynuclein toxicity can be envisaged, with either being the disease-initiating factor yet acting together during disease progression. …”
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Changing Management of Clinical Low-Stage Testicular Cancer by Timothy Gilligan

“…In addition, growing concern about radiation-induced cancers and other late toxicity has dulled enthusiasm for radiotherapy as a treatment for stage I seminomas. …”
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Zeaxanthin: Review of Toxicological Data and Acceptable Daily Intake by James A. Edwards

“…Subchronic OECD guideline studies with mice and rats receiving beadlet formulations of high purity synthetic zeaxanthin in the diet at dosages up to 1000 mg/kg body weight (bw)/day, and in dogs at over 400 mg/kg bw/day, produced no adverse effects or histopathological changes. In developmental toxicity studies, there was no evidence of fetal toxicity or teratogenicity in rats or rabbits at dosages up to 1000 or 400 mg/kg bw/day, respectively. …”
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Effect of Silver Nanoparticles on Tropical Freshwater and Marine Microalgae by Thanh-Luu Pham

“…The results suggested that AgNPs presented different toxicity mechanisms for microalgae and showed to be more toxic in freshwater than in marine environment. …”
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Lipid - Lowering Effect of a Mixture of Allium cepa bulb and Camellia sinensis Leaf Extracts in Rats fed on High fat Diet by R, Kimanje K, K, Ssekatawa, M, . Tirwomwe, Hellen, W. Kinyi

“…It reduced body weight, total cholesterol, triacylglycerides, LDL-cholesterol and increased HDL, and in addition it had no toxicity to the liver of the animal models used. It has thus been recommended as a potential therapy for hyperlipidemia and its associated complication of liver toxicity. …”
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Optimal treatment approach for intracranial germinoma: a systematic review and meta-analysis by Zhirui Zhou, Jiabing Liu, Qi Yue, Lingxiao Chen, Xiwei Zhang, Xin Lin, Lin Zheng, Enmin Wang, Yang Wang, Ying Mao

“…Total 24 studies reported treatment-related acute and/or late toxicity, combination CTx increased acute toxic, and expanded RT field and/or dose increased late toxicity. …”
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Oxidative stress caused by 3-monochloro-1,2-propanediol provokes intestinal stem cell hyperproliferation and the protective role of quercetin by Zongzhong Liu, Yanfei He, Yuhan Wang, Kefeng Ren, Pengpeng Xia, Binbin Xie, Tian Wei

“…Recently, the contaminant 3-monochloropropane-1,2-diol (3-MCPD) found in food and the environment has garnered significant global attention due to its detrimental health effects on animals, including reproductive toxicity, neurotoxicity, and nephrotoxicity. However, the specific impacts and mechanisms of 3-MCPD on intestinal health remain elusive. …”
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Separate Evaluation of the Effects of Hydroalcoholic Extracts of Eryngium Caucasicum L. and Zataria Multiflora L. on Gastric Ulcers in an Animal Model by mahdi Jalahi, Mohammad Azadbakht, Jafar Akbari, Fereshteh Talebpuor, Fatemeh Akbari

“…Cultivated Artemia salina was used to evaluate the toxicity of the extracts. The animal study was conducted using eight groups of Balb/c mice. …”
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Salvage Magnetic Resonance Imaging–guided Transurethral Ultrasound Ablation for Localized Radiorecurrent Prostate Cancer by Mikael Anttinen, Pietari Mäkelä, Pertti Nurminen, Heikki Pärssinen, Simona Malaspina, Teija Sainio, Mikael Högerman, Pekka Taimen, Roberto Blanco Sequeiros, Peter J. Boström

“…Background and objective: Toxicity from local salvage therapy for radiorecurrent prostate cancer (PCa) remains a concern. …”
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Transcriptome analysis unveils the mechanisms of oxidative stress, immunotoxicity and neurotoxicity induced by benzotriazole UV stabilizer-328 in zebrafish embryos by Xinlu Yang, Yijing Gan, Menghuan Zhang, Shaolin Xie, Mingfu Lin, Lixiang Zhong, Mengke Song, Jun Wang, Yumei Huang

“…As an emerging pollutant, ultraviolet stabilizer-328 (UV-328) has been frequently detected in aquatic environments and attracted great attention. Nevertheless, the toxicity and mechanisms of UV-328 to aquatic organisms are still not fully understood. …”
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Novel organophosphate esters and their transformation products in offshore sediment from Eastern China: Occurrence, temporal trend, and risk assessment by Meng Gao, Yu Wang, Liman Wei, Siyuan Li, Qiuyue Zhang, Zhongkang Yang, Mohan Bai, Yiming Yao, Lei Wang, Hongwen Sun

“…Generally, the acute toxicity-based predicted no-effect concentrations for studied compounds were 1 to 2 orders of magnitude lower than those based on chronic toxicity. …”
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Phytochemical Analysis, Antioxidant Activity, Antimicrobial Activity, and Cytotoxicity of Chaptalia nutans Leaves by Letiele Bruck de Souza, Amanda Leitão Gindri, Thainara de Andrade Fortes, Thais Felli Kubiça, Jefferson Enderle, Rafael Roehrs, Sidnei Moura e Silva, Vanusa Manfredini, Elton Luís Gasparotto Denardin

“…TBARS, carbonyl protein, and DCFH demonstrate that the extract has the ability to protect the cell from protein and lipid damage, as well as the inhibition of oxygen-derived radicals at the three concentrations tested: 0.1, 1, and 10 mg/mL. Regarding the toxicity of C. nutans extract against D. melanogaster, it was found that until the concentration of 15 mg/mL, the extract showed no toxicity and that the LC50 obtained was 24 mg/mL. …”
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Magnetic Solid Phase Extraction as a Promising Technique for Fast Separation of Metallic Nanoparticles and Their Ionic Species: A Review of Recent Advances by Ingrid Hagarová

“…However, nanoparticles and their ionic species can coexist and their toxicity may differ; therefore, novel analytical approaches are necessary to monitor not only the nanoparticles but also their ionic species. …”
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Bioactivity of Powder and Extracts from Garlic, Allium sativum L. (Alliaceae) and Spring Onion, Allium fistulosum L. (Alliaceae) against Callosobruchus maculatus F. (Coleoptera: Br... by Abiodun A. Denloye

“…On the basis of 48 hr median lethal toxicity (LC50), test plant powders and extracts from A. sativum were more toxic to C. maculatus adults than those from A. fistulosum. …”
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Molecular Docking, Dynamics Simulations, ADMET, and DFT Calculations: Combined In Silico Approach to Screen Natural Inhibitors of 3CL and PL Proteases of SARS-CoV-2 by Sugumar Mohanasundaram, Porkodi Karthikeyan, Venkatesan Sampath, M. Anbazhagan, Sundramurthy Venkatesa Prabhu, Jamal M. Khaled, Muthu Thiruvengadam

“…There is no significant toxicity identified.…”
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Exposure of cerebellar granule cells to nanosilver: Oxidative stress parameters and the protective effect of exogenous glutathione by Lidia Struzynska, Beata Toczylowska, Beata Dabrowska-Bouta, Elzbieta Zieminska

“…Due to the risk of environmental hazards, the mechanisms of AgNPs toxicity should be thoroughly investigated to deepen our understanding of the potential negative impact on human health. …”
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Expression, Purification, and Functional Analysis of Novel RelE Operon from X. nematophila by Jitendra Singh Rathore, Lalit Kumar Gautam

“…The expression of recombinant Xn-relE under tightly regulated ara promoter in E. coli Top 10 cells confirms its toxic nature in endogenous toxicity assay. The neutralization activity in endogenous toxicity assay by Xn-relEAT antitoxin confirms its antidote nature when studying the whole TA operon under ara regulated promoter. …”
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Cardiorenal Effects of Newer NSAIDs (Celecoxib) versus Classic NSAIDs (Ibuprofen) in Patients with Arthritis by Ragia Hegazy, Mohamed Alashhab, Madiha Amin

“…To study cardiorenal toxicity of celecoxib versus ibuprofen in arthritic patients. …”
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Phytochemical content, antibacterial, antioxidant and cytotoxic activities, of leaves extracts of Eucalyptus globulus, Peltophorum africanum and Vangueria infausta by Portia Mamothaladi Moshidi, Johnfisher Mupangwa, Claude Mukengela Muya, Soul Washaya

“…The antibacterial activity was lower (P < 0.05) for P. africanum and E. globulus oil, and was strongly related to the presence of phenolics and flavonoids. The lack of toxicity of plant extracts suggests that extracts can be used as animal feed additives with no risk of toxicity. …”
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