Cardiac Transplantation following Cobalt Cardiomyopathy from Bilateral Metal-on-Metal Hip Replacements by Peter Szedlak, Amrik Virdi, Paul Cacciottolo, Stephen Shepherd, Stephen Pettit, Florian Falter

“…Following a prolonged period of deterioration without a clear cause, the diagnosis of cobalt toxicity-related cardiomyopathy due to cobalt-chromium alloy hip prostheses was eventually made. …”
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High on Cannabis and Calcineurin Inhibitors: A Word of Warning in an Era of Legalized Marijuana by Naomi Hauser, Tanmay Sahai, Rocco Richards, Todd Roberts

“…Tacrolimus toxicity can be severe and may include multiorgan damage. …”
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Effect of spirulina supplementation on growth, immunity, antioxidant status and pathomorphological perspectives in broilers exposed to dietary aflatoxin B1 by Ayman S. Salah, Antonia Lestingi, Mahmoud S. El-Tarabany, Marwa Mostafa, Rania Samir Zaki, Mahmoud M. Azzam, Alessandro Di Cerbo, Mahmoud Alagawany, Ahmed Fotouh

“…AFB1 toxicity reduced the activity of SOD and GPx (P < 0.05). …”
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Acute enteritis with pelvic SBRT: Influence of bowel delineation methods by Akshay Dinesan, Maneesh Singh, Prachi Mehta, Priyamvada Maitre, Vedang Murthy

“…Patients with acute bowel toxicity (CTCAE v5.0) were included as cases while those without were controls. …”
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Bioassays and virtual screening to identify potent natural antifouling compounds from the brown macroalga Dictyota dichotoma by Ba-akdah Mohammad Abdulaziz, Satheesh Sathianeson

“…The metabolites also showed positive for crustacean and fish toxicity in toxicity prediction using an in silico method.…”
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Outcome differences by sex in oncology clinical trials by Ashwin V. Kammula, Alejandro A. Schäffer, Padma Sheila Rajagopal, Razelle Kurzrock, Eytan Ruppin

“…Abstract Identifying sex differences in outcomes and toxicity between males and females in oncology clinical trials is important and has also been mandated by National Institutes of Health policies. …”
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Plants with known antagonistic properties against pests: how they influence non-target free-living soil fauna? by Kassimira Ilieva-Makulec, Michał Bielecki, Grzegorz Makulec

“…The toxicity of the hemp extract showed a clear dependence on its concentration. …”
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Toxicological Assessment of Pseudospondias microcarpa (A. Rich.) Engl. Hydroethanolic Leaf Extract in Rats: Haematological, Biochemical, and Histopathological Studies by Donatus Wewura Adongo, Priscilla Kolibea Mante, Kennedy Kwami Edem Kukuia, Charles Kwaku Benneh, Robert Peter Biney, Eric Boakye-Gyasi, Nicholas Akinwale Titiloye, Eric Woode

“…However, although parts of the plant are extensively used in African traditional medicine, no scientific study has been reported on its toxicity. Therefore, this study evaluated the acute and subacute toxicity studies of the ethanolic extract of P. microcarpa in rats. …”
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Prevalence, Dispersion and Nature of Bioaerosols over a Solid Landfill Site in Central India by Priyanka D. Bhoyar, Pooja Kamdi, Amit Bafana, Panuganti C. S. Devara, Saravanadevi Sivanesan, Amrit Kumar, Kannan Krishnamurthi

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The Effects of Polystyrene Microplastics and Copper Ion Co-Contamination on the Growth of Rice Seedlings by Huiyu Jin, Guohe Lin, Mingzi Ma, Lin Wang, Lixiang Liu

“…While PS-MPs can alleviate Cu toxicity by reducing its bioavailability, they also compromise antioxidant activity, potentially affecting plant resilience to stress. …”
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Temperature effects on the hormetic response of Myzus persicae after sublethal exposure to insecticides by Ana Paula Nascimento Silva, Camila Faria Chagas, Emanuel Lucas de Andrade Alves, Vinícius de Castro Carvalho, Khalid Haddi

“…It can also affect the toxicity and relative efficacy of insecticides that are used in agricultural fields. …”
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Diversity and functions of fungal VOCs with special reference to the multiple bioactivities of the mushroom alcohol by Guohua Yin, Geromy G. Moore, Joan Wennstrom Bennett

“…When Drosophila was cultivated in an atmosphere shared with VOC mixtures released from growing cultures of several medically important fungi, including Aspergillus fumigatus, toxicity was observed. Additionally, we propose that components of the genetic immune system of D. melanogaster are engaged in the toxicity of fungal VOCs mainly via the elicitation of the Toll pathway. …”
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A Bayesian phase 2 model based adaptive design to optimise antivenom dosing: Application to a dose-finding trial for a novel Russell's viper antivenom in Myanmar. by James A Watson, Thomas Lamb, Jane Holmes, David A Warrell, Khin Thida Thwin, Zaw Lynn Aung, Min Zaw Oo, Myat Thet Nwe, Frank Smithuis, Elizabeth A Ashley

“…The design formalises the optimal initial dose of antivenom as the dose closest to that giving a pre-specified desired efficacy, but resulting in less than a pre-specified maximum toxicity. For Daboia siamensis envenoming, efficacy is defined as the restoration of blood coagulability within six hours, and toxicity is defined as anaphylaxis. …”
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Delphi study to identify consensus on patient selection for hydrogel rectal spacer use during radiation therapy for prostate cancer in the UK by Amit Bahl, Suneil Jain, Albert Edwards, Rhodri Saunders, Clive Peedell, Heather Ann Payne, James Andrew Thomas, Prantik Das, Amanda Hansson Hedblom, Emily Woodward

“…There was agreement that despite meeting rectal dose constraints, too many patients experience rectal toxicity and that rectal hydrogel spacers in eligible patients significantly reduces toxicity-related adverse events. …”
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Optimization of anthracene biodegradation by indigenous Trichoderma lixii and Talaromyces pinophilus using response surface methodology by Samson O. Egbewale, Ajit Kumar, Mduduzi P. Mokoena, Ademola O. Olaniran

“…Despite reduced toxicity, both strains were classified as harmful based on effective concentration (EC50) and toxicity unit (TU) (20.92±1.32 mg/L and 4.78 % for TlFLU1 and 35.29±1.55 mg/L and 2.83 % for TpFLU12). …”
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Comprehensive Insight of Neurodegenerative Diseases and The Role of Neurotoxin Agents — Glutamate by Hui-Min Yap, Kwan-Liang Lye, Loh Teng-Hern Tan

“…Whereas non-receptor mediated oxidative toxicity involved the breakdown of the cystine/glutamate antiporter (xc - ) mechanism, which leads to the depletion of glutathione (GSH) and causes oxidative stress and cell death. …”
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Systematic Review of Focal Prostate Brachytherapy and the Future Implementation of Image-Guided Prostate HDR Brachytherapy Using MR-Ultrasound Fusion by M. Sean Peach, Daniel M. Trifiletti, Bruce Libby

“…Further, we wanted to determine if focal treatment results in less toxicity. Utilizing the Medline repository, dosimetric papers comparing whole gland to partial gland brachytherapy and clinical papers that reported toxicity of focal brachytherapy were selected. …”
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Hypoglycaemic, anti-hyperlipidemic, and anti-inflammatory activities of Asparagus africanus (Asparaceae) extract on high-fat diet/streptozotocin-induced diabetes in Wistar rats by Focham Evans Ngwenah, Oumar Mahamat, Tume Christopher

“…Objective: To investigate the toxicity and effect of the extract on some complications of diabetes in Wistar rats. …”
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Accounting for microorganisms yields stricter water quality criteria and elevated ecological risks of antibiotics: A case study of sulfonamides in the Yangtze River Delta by Xinyang Zhang, Xiao Yun, Ye Huang, Guofeng Shen, Nan Lin

“…The derivation of water quality criteria (WQC) for antibiotics is influenced by the inclusion of various organisms' toxicity data, including microbial data, though no definitive conclusions have been reached. …”
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Antihyperlipidemic Potential of Polyphenol and Glycoside Rich Nerium oleander Flower against Triton WR-1339-Induced Hyperlipidemia in Experimental Sprague Dawley Rats by V. Gayathri, S. Ananthi, Hannah R. Vasanthi

“…In the present study, we have evaluated the toxicity profile of the 50% hydroethanolic extracts of Nerium oleander flowers (ENO) using in vitro brine shrimp lethality assay and MTT cytotoxicity assay and in vivo acute toxicity test as per the OECD guidelines. …”
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