Showing 961 - 980 results of 4,481 for search '"Toxicity"', query time: 0.07s Refine Results
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    CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases by Arthur I. Cederbaum, Lili Yang, Xiaodong Wang, Defeng Wu

    Published 2012-01-01
    “…A major mechanism is the role of lipid peroxidation and oxidative stress in alcohol toxicity. Many pathways have been suggested to play a role in how alcohol induces oxidative stress. …”
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    A humanized anti-MSLN×4-1BB bispecific antibody exhibits potent antitumour activity through 4-1BB signaling activation and fc function without systemic toxicity by Da-yan Zhang, Zhi-hua Zhang, Wen-ting Liu, Wei-ming Zhou, Peng-fei Zhou, Juan-juan Wei, Xue-jing Dai, Xiao-li Zeng, Yu-qiong Zhou, Han-wang Li, Heng Zhang, Ao-lin Shen, Lian-sheng Cheng, Guo-dong Shen, Yi-fu He

    Published 2025-01-01
    “…Abstract Background Agonistic monoclonal antibodies targeting 4-1BB/CD137 have shown preclinical promise, but their clinical development has been limited by severe liver toxicity or limited efficacy. Therefore, a safe and efficient immunostimulatory molecule is urgently needed for cancer immunotherapy. …”
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    A Low-Cost Electrochemical Cell Sensor Based on MWCNT-COOH/α-Fe<sub>2</sub>O<sub>3</sub> for Toxicity Detection of Drinking Water Disinfection Byproducts by Ying Liu, Zhipeng Zhang, Yuling Wu, Huan Yang, Jiao Qu, Xiaolin Zhu

    Published 2025-01-01
    “…Moreover, the safety of these DBPs has not been sufficiently assessed, underscoring the need for a comprehensive evaluation of their toxic effects and associated health risks. Compared to traditional methods for studying the toxicity of pollutants, emerging electrochemical sensing technologies offer advantages such as simplicity, speed, and sensitivity, presenting an effective means for toxicity research on pollutants. …”
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