Immunomodulatory Effect of Phage Depolymerase Dep_kpv74 with Therapeutic Potential Against K2-Hypervirulent <i>Klebsiella pneumoniae</i> by Nikolay V. Volozhantsev, Maria A. Makarova, Alena S. Kartseva, Marina V. Silkina, Valentina M. Krasilnikova, Egor A. Denisenko, Alexander I. Borzilov, Victoria V. Firstova

“…The biochemical results of the studies indicated that Dep_kpv74 did not exert any toxic effects on liver and kidney functions. The results of the analysis of lymphocyte proliferative activity demonstrated that Dep_kpv74 depolymerase has a mild immunomodulatory effect. …”
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Olfactory Impairment and Recovery in Zebrafish (<i>Danio rerio</i>) Following Cadmium Exposure by Chiara Maria Motta, Rosa Carotenuto, Chiara Fogliano, Luigi Rosati, Pabitra Denre, Raffaele Panzuto, Rossana Romano, Gianluca Miccoli, Palma Simoniello, Bice Avallone

“…Present in high concentrations across water bodies, cadmium is known to bioaccumulate and biomagnify throughout the food chain. While the toxic effects of cadmium on the organs and tissues of aquatic species are well-documented, little is known about its impact on sensory systems crucial for survival. …”
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Influence of Omega-3 and Green Tea Extract on Alcohol-Induced Liver Injury in Rats by Ridha Hassan Hussein, Zana Hassan Ibrahim

“…Drinking alcoholic beverages recently is common in many parts of the world, liver is a principal organ that involved in toxic effects of alcohol and it remains a serious health problem globally. …”
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Programmed neurite degeneration in human central nervous system neurons driven by changes in NAD+ metabolism by Markus Brüll, Selina Multrus, Michael Schäfer, Ivana Celardo, Christiaan Karreman, Marcel Leist

“…The establishment of a CNS axotomy model (using modified 3D LUHMES cultures) allowed us to study metabolic control of ND in human midbrain-derived neurons without the use of toxicants or other direct disturbance of cellular metabolism. …”
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Medicinal plants as alternatives for the management of hypertension and diabetes in Nigeria: Analysis of the structured interview of Nigerian patients by Rosemary A. Sylver-Francis, Olavi Pelkonen

“…Potentially, the use may predispose patients to severe hypotension or hypoglycaemia and other adverse effects e.g. drug interactions and direct toxicities. Also, poor quality and scanty or anecdotal directions of TMPs raises safety concerns. …”
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Cytotoxicity and genotoxicity of orthodontic bands after aging: an in-vitro study by Maryam Karandish, Bahar Khademi, Golnaz Ziaei, Nasrollah Erfani, Leila Moezi, Zahra Faghih

“…However, AO bands seem to become toxic for gingiva cells in acidic milieu.…”
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How the Suboxone Education Programme presented as a solution to risks in the Canadian opioid crisis: a critical discourse analysis by Quinn Grundy, Fiona Webster, Daniel Z Buchman, Sheryl Spithoff, Ross E G Upshur, Abhimanyu Sud, Matthew Strang

“…Discursive themes were identified through iterative and duplicate analyses using a semistructured data extraction instrument.Results Documents characterised the Programme as addressing iatrogenic risks from overprescribing opioid analgesics, environmental risks from a toxic street drug supply and pharmacological risks relating to the dominant therapeutic alternative of methadone. …”
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Cobalt-induced oxidative stress and defense responses of Adhatoda vasica proliferated shoots by Abeer A. Radi, Fatma A. Farghaly, Fatma A. Al-Kahtany, Ahmed M. Zaher, Afaf M. Hamada

“…While cobalt (Co) can be toxic to plants at high levels and isn’t considered essential, it plays a beneficial role in many enzymes and is critical for various biological functions. …”
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Compounds Involved in the Invasive Characteristics of <i>Lantana camara</i> by Hisashi Kato-Noguchi, Midori Kato

“…Lantadenes A and B, oleanonic acid, and icterogenin are highly toxic to herbivore mammals, and β-humulene, isoledene, α-copaene thymol, and hexadecanoic acid have high insecticidal activity. β-Caryophyllene and <i>cis</i>-3-hexen-1-ol may function as herbivore-induced plant volatiles which are involved in sending warning signals to undamaged tissues and the next plants of the same species. …”
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Synthesis of Silver and Zinc Oxide Nanoparticles Using Polystichum lentum Extract for the Potential Antibacterial, Antioxidant, and Anticancer Activities by Deepak Kumar Shrestha, Akash Budha Magar, Manisha Bhusal, Rabina Baraili, Ishwor Pathak, Pusp Raj Joshi, Niranjan Parajuli, Khaga Raj Sharma

“…Both nanoparticles and aqueous extract were mildly toxic towards the brine shrimp nauplii with the lowest LC50 being 661.80 ± 64.21 μg/mL for the aqueous extract. …”
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Mixture of MMP-2, MLC, and NOS Inhibitors Affects NO Metabolism and Protects Heart from Cardiac I/R Injury by Anna Krzywonos-Zawadzka, Aleksandra Franczak, Grzegorz Sawicki, Iwona Bil-Lula

“…Increased production of toxic peroxynitrite (ONOO−) during oxidative stress is a source of increased nitration/nitrosylation of contractile proteins, which enhance their degradation through MMP-2. …”
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Purification and Characterization of Hemagglutinating Proteins from Poker-Chip Venus (Meretrix lusoria) and Corbicula Clam (Corbicula fluminea) by Chin-Fu Cheng, Shao-Wen Hung, Yung-Chung Chang, Ming-Hui Chen, Chen-Hsuan Chang, Li-Tse Tsou, Ching-Yu Tu, Yu-Hsing Lin, Pan-Chen Liu, Shiun-Long Lin, Way-Shyan Wang

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In vitro evaluation of glutathione implementation on oxidative dna damage and oxidant status in high glucose conditions by Fatmagul Yur, Semiha Dede, Sedat Cetin, Mehmet Taspinar, Ayse Usta

“…On the other hand, it was revealed that the applied amounts of glutathione in the process did not cause any toxic effects.…”
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Economic Spectrofluorometric Bioanalysis of Empagliflozin in Rats’ Plasma by Bassam Ayoub, Noha El Zahar, Haidy Michel, Mariam Tadros

“…Moreover, development of new simple cost-effective methods is necessary to give the researchers a set of “varieties” that they can use according to the laboratory limitations, especially in the developing countries in addition of being a greener method due to the lower consumption of toxic solvents and lower waste production.…”
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High-field MRI findings in epileptic dogs with a normal inter-ictal neurological examination by Stephanie Phillipps, Rita Goncalves

“…To be included in the study, patients had to have a normal neurological examination, high-field MRI of the brain and have had metabolic and toxic causes excluded.ResultsFour hundred and twelve dogs were eligible for inclusion. …”
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Virgin coconut oil lessens trichloroacetic acid assault on the stomach and intestine of rats via enhancement of Nrf2 but inhibition of TNF-α, IL1β/NF-kB signalling pathway by OO Oladokun, KO Ajeigbe, MA Adelakun

“…Background: Trichloroacetic acid (TCA), a known environmental toxicant, causes organ damage via oxidative stress and activation of pro-inflammatory cytokines. …”
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Pharmacological pain management in patients with rheumatoid arthritis: a narrative literature review by Natasha Cox, Christian D. Mallen, Ian C. Scott

“…Consequently, pain care is often suboptimal, with growing evidence that analgesics are widely prescribed to patients with RA, despite potential toxicities and limited evidence for efficacy. Our review provides an overview of pharmacological treatments for pain in patients with RA, summarising their efficacy and use. …”
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Effects of shrimp chitosan based edible coating on the shelf life of selected vegetables in context of attaining SDGs by Munir Ibn Mahin, Md. Harun-Ar Rashid, Abdul Rabbi Mredul

“…Polysaccharide coatings, particularly chitosan, have gained popularity as biopolymer-based coatings for prolonging the postharvest shelf life of fruits and vegetables, owing to their biodegradable and non-toxic properties. This study aimed to assess the characteristics of chitosan obtained from shrimp (Penaeus monodon) shells and uses it as coatings to prolonging the shelf life of tropical vegetables. …”
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Industrial Potential of Two Varieties of Cocoyam in Bread Making by Nnabuk O. Eddy, Emmanuel Essien, Eno E. Ebenso, Richard A. Ukpe

“…The evaluation of the chemical (proximate composition, mineral composition, toxicant composition and vitamin composition), nutritional and industrial potentials of two varieties of cocoyam (Xanthosoma sagittifolium (XS) and Colocasia esculenta (CE) were carried out using recommended methods of analysis. …”
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Genome wide identification of MATE and ALMT gene family in lentil (Lens culinaris Medikus) and expression profiling under Al stress condition by Ankita Tripathi, Dharmendra Singh, Jyotika Bhati, Deepti Singh, Jyoti Taunk, Jawaher Alkahtani, Abdulrahman Al-Hashimi, Madan Pal Singh

“…Abstract Background The membrane transporters viz. multidrug and toxic compound extrusion (MATE) and aluminum-activated malate transporter (ALMT) are associated with aluminum (Al) tolerance by accelerating secretion of organic acids, which can influence nutrient availability and stress response. …”
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