Immunotherapies to Nano-Immunotherapies: Advances in Immune Targeting in Bladder Cancer by Beatriz Ramos, Dakota Rogers

“…However, challenges such as toxic side-effects, variable response rates and the need for predictive biomarkers persists. …”
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Prevalence of Hypertension in Area I Cienfuegos Municipality. Second Measurement of CARMEN Initiative by Hilda María Delgado Acosta, Karelis Lastre Navarro, María Lina Valdés Gómez, Mikhail Benet Rodríguez, Alain Francisco Morejón Giraldoni, Juan Rafael Zerquera Rodríguez

“…<strong>Background:</strong> the prevalence of hypertension has increased, associated to inadequate alimentary patterns, decrease of physical activity, and other behaviour patterns related to toxic habits. <strong><br />Objective:</strong> characterizing the prevalence of hypertension in the Area I Cienfuegos in 2010 - 2011. …”
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Mini review of spatially fractionated radiation therapy for cancer management by Shrikant B. Mali

“…Spatially fractionated radiation therapy (SFRT) is a non-uniform dose distribution technique that has shown high rates of clinical response with minimal toxicities in large-volume primary or metastatic malignancies. …”
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Comparative Study of Heavy Metal Concentration in Eggs Originating from Industrial Poultry Farms and Free-Range Hens in Kosovo by H. Aliu, S. Dizman, A. Sinani, G. Hodolli

“…Therefore, egg consumption does not exceed the safety levels of toxic metals and does not pose any risk to human health.…”
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Petroleum Hydrocarbons Contamination Profile of Ochani Stream in Ejamah Ebubu, Eleme Local Government Area of Rivers State, Nigeria by Akuro Adoki

“…At an estimated average depth of 150mm over an area of 6.05 Ha the total volume of contaminated soil/sediment was 9075m3. The levels of toxic species such as heavy metals, PAH and BTEX compounds were found to be very low and they do not pose a significant environmental hazard. …”
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Fipronil in sub-lethal doses leads to immuno-toxicological effects in broiler birds. by Shafia Tehseen Gul, Muhammad Zergham Tahir, Latif Ahmad, Aisha Khatoon, Muhammad Kashif Saleemi, Farid Shokry Ataya, Riaz Hussain, Bakhtawar Maqbool, Dalia Fouad, Ahrar Khan

“…Results also revealed that the bursa of Fabricius thymus and spleen were also affected due to the toxic effect of fipronil, even at sub-lethal doses.…”
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Cytotoxicity Evaluation of Different Types of CAD/CAM Blocks by Fikret Özgür Coşkun, Semanur Özüdoğru, Mustafa Hayati Atala, Giray Buğra Akbaba

“…It has been shown that all blocks whose cytotoxic effects were investigated did not cause any toxic effects (except VM and LU for 24 h) at different application times (24 h and 48 h). …”
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ON THE ISSUE OF ASSESSING THE ECOLOGICAL STATE OF VARIOUS WATERCOURCES IN THE CONDITIONS OF ANTHROPOGENIC PRESSURE by Elena A. Shashulovskaya, Svetlana A. Mosiyash, Olga V. Shashulovskaya, Irina G. Filimonova, Liliya V. Grishina, Elena G. Kuzina

“…Hydro/chemical studies included indicators of oxygen regime, salt composition, organic matter, biogenic and toxic elements. The calculated SCWPI fluctuated in the range of 3,0–5,4, which corresponds to the quality category “very polluted” - “dirty”. …”

The impact of climate change on the natural dendroflora of the greater caucasus by Baghirova Samira

“…The soil layer of the Kapychay site 0-30 cm was found to have low organic matter (humus) content, and the magnesium level in water samples from the Lakit River was toxic. The data obtained during the study of climatic and anthropogenic impacts on the vegetation cover of the region can contribute to the development of measures aimed at developing scientific research and expanding environmental protection measures to preserve biodiversity in the future.…”
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Automatic tool for the reconciliation of serious adverse events for pharmacovigilance: design and implementation of Reconciliaid by Sara Contu, Renaud Schiappa, Yann Chateau, Emmanuel Chamorey

“…Background: Reporting serious adverse events (SAEs) is crucial to reduce or avoid toxicities that can lead to major consequences for patient’s health due to treatments tested in clinical trials. …”
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Methicillin-Resistant Staphylococcus aureus: Docking-Based Virtual Screening and Molecular Dynamics Simulations to Identify Potential Penicillin-Binding Protein 2a Inhibitors from... by Motahareh Masumi, Fatemeh Noormohammadi, Fatemeh Kianisaba, Fatemeh Nouri, Mohammad Taheri, Amir Taherkhani

“…Staphylococcus aureus (S. aureus) is responsible for several disorders including skin and soft tissue infections, bacteremia, pulmonary infections, septic arthritis, osteomyelitis, meningitis, gastroenteritis, toxic-shock syndrome, and urinary tract infections. …”
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Canagliflozin alleviates acetaminophen-induced renal and hepatic injury in mice by modulating the p-GSK3β/Fyn-kinase/Nrf-2 and p-AMPK-α/STAT-3/SOCS-3 pathways by Abeer Bishr, Bassant M. El-Mokadem, Asmaa A. Gomaa

“…Aim: Our study assessed the novel effect of Cana against APAP-induced toxicities. Main methods: mice were randomized into five groups: negative control, Cana25, APAP, Cana10 + APAP, and Cana25 + APAP. …”
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Postharvest Handling Practices and Perception of Potato Safety among Potato Traders in Nairobi, Kenya by Consolata Nolega Musita, Michael Wandayi Okoth, George Ooko Abong’

“…Exposure of the potato to unfavorable conditions such as light, extreme temperatures, and bruising can result in accumulation of glycoalkaloids, which are toxic substances. This study was a cross-sectional survey which aimed to investigate the postharvest handling practices of potatoes and perception of potato safety among open air market traders in Nairobi County, Kenya. …”
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Quantitative Analysis of Heavy Metals and Organic Compounds in Soil from Deir Kanoun Ras El Ain Dump, Lebanon by Jamilah Borjac, Manal El Joumaa, Lobna Youssef, Rawan Kawach, Diane A. Blake

“…The aim of this study was to determine the levels of some toxic heavy metals and organic compounds in different soil samples collected from the dump and along the canal during winter and summer seasons. …”
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Selective mPGES-1 Inhibitor Ameliorated Adjuvant-Induced Arthritis in the Rat Model by Min Ji Kim, Hwi-Ho Lee, Choi Kim, Ja Yeon Lee, Kyung-Sook Chung, Kyung-Tae Lee, Jae Yeol Lee

“…MPO-0144 attenuated the inflammatory responses without severe gastrointestinal side effects and organ toxicities. These overall data suggest a possibility that MPO-0144 downregulates PGE2 production by potent mPGES-1 and weak COX-2 inhibitory activities, thus attenuating the paw swelling in AIA (adjuvant-induced arthritis) rat models. …”
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The Importance of Natural Indigo Dye and Its Revitalization and Ethiopian Potential for Indigo Growing by Abera Kechi Kabish, Molla Tadesse Abate, Zelalem Adane Alemar, Solomon Girmay

“…The use of excessive and toxic synthetic dyes in textile and apparel manufacturing processes lineages environment pollution and health hazards to the surroundings where they are sited. …”
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Formation of volatile compounds in salt-mediated naturally fermented cassava by Alberta N.A. Aryee, Christabel Tachie, Aleksei Kaleda

“…Fermentation has been used to improve shelf-life, functional properties, nutrient bioavailability, minimize toxic compounds, and alter aroma. In this study, the effect of added salt (5–25 %) on the pH, titratable acidity (TTA), and volatile compounds (VOCs) in cassava fermented was investigated. …”
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Association between Particulate Matter Pollution Concentration and Hospital Admissions for Hypertension in Ganzhou, China by Chenwei Li, Xinye Zhou, Kun Huang, Xiaokang Zhang, Yanfang Gao

“…Fine particulate matter (PM2.5) and respirable particulate matter (PM10) are two major air pollutants with toxic effects on the cardiovascular system. Hypertension, as a chronic noncommunicable cardiovascular disease, is also a risk factor for several diseases. …”
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Biochemical characterization of the human ubiquitous glucose‐6‐phosphatase in neutrophil granulocytes by Zsigmond Lédeczi, Klaudia Németh, Tamás Kardon

“…Recently, G6PC3 has been shown to play an important role in neutrophil granulocytes, eliminating the toxic metabolite 1,5‐anhydroglucitol‐6‐phosphate. …”
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Hereditary Tyrosinemia Type 1 in Jordan: A Retrospective Study by Noor A. Megdadi, Ahmad K. Almigdad, Mo’men O. Alakil, Shahrazad M. Alqiam, Sumaia G. Rababah, Moshera A. Dwiari

“…The accumulation of tyrosine toxic metabolites leads to progressive hepatic, renal, and neurological manifestations. …”
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