β-Carboline Alkaloids and Essential Tremor: Exploring the Environmental Determinants of One of the Most Prevalent Neurological Diseases by Elan D. Louis, Wei Zheng

“…Additional studies are needed to establish more definitively whether these toxic exposures are associated with ET and are of etiological importance.…”
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The role of circadian rhythm regulator PERs in oxidative stress, immunity, and cancer development by Baimei Zhao, Eugenie Nepovimova, Qinghua Wu

“…PERs in innate immune cells modulate the temporal patterns of NF-κB and TNF-α activities, as well as the response to LPS-induced toxic shock, initiating inflammatory responses that escalate into chronic inflammatory conditions. …”
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Green Synthesize and Characterization of Copper Nanoparticles Using Iranian Propolis Extracts by Yasamin Seyyed Hajizadeh, Naser Harzandi, Ebrahim Babapour, Mohsen Yazdanian, Reza Ranjbar

“…Research on green methods for making metal oxide NPs is gaining momentum to safeguard the environment from the potential dangers associated with toxic chemicals. This study aimed to synthesize copper NPs (CuNPs) via propolis extraction, a novel application of nanoscience. …”
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Natural products as anticancer agents and enhancing their efficacy by a mechanism-based precision approach by Stephen Safe

“…A mechanism-based precision medicine approach should enhance the clinical efficacy of dietary and related natural products as anticancer agents and decrease toxic side effects for some combination therapies.…”
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Analysis of Treated Wastewater Produced from Al-Lajoun Wastewater Treatment Plant, Jordan by Waleed Manasreh, Atef S. Alzaydien, Malahmeh .M

“…The treated wastewater contained some organic compounds of toxic type such as polycyclic aromatic hydrocarbons. …”
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Evaluation of nigella sativa's cold press oil as vaccine adjuvant by Uçkun Sait Uçan, Aslı Sakmanoğlu, Ali Uslu, Zafer Sayın, Ecem Oğlakçı Cansoy

“…<b>Aim: </b>In order to identify an organic and plant based, less toxic, cheaper and more effective adjuvant, a cold pressed oil of Nigella sativa (CPNSO) and one of the essential components of Nigella sativa oil (NSO), thymoquinone (Thymoquinone ) were investigated as adjuvant candidates.…”
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Development of Micellar HPLC-UV Method for Determination of Pharmaceuticals in Water Samples by Danielle Cristina da Silva, Cláudio Celestino Oliveira

“…Method for extraction and determination of amoxicillin, caffeine, ciprofloxacin, norfloxacin, tetracycline, diclofenac, ibuprofen, nimesulide, levonorgestrel, and 17α-ethynylestradiol exploiting micellar liquid chromatography with PDA detector and solid-phase extraction was proposed. The usage of toxic solvents was low; the chromatographic separation of the medicaments was performed using a C18 column and mobile phases A and B containing 15.0% (v/v) ethanol, 3.0% (m/v) sodium dodecyl sulfate (SDS), and 0.02 mol·L−1 phosphate at pHs 7.0 and 8.0, respectively. …”
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Synthesis, characterization, antimicrobial, antioxidant, and anti-cancer activity of new hybrid structures based on benzimidazole and thiadiazole by Hayrani Eren Bostancı, Ulviye Acar Çevik, Ayşen Işık, Zahra Maryam, Ufuk İnce, Yusuf Özkay, Zafer Asım Kaplancıklı

“…The compound 5g stands out in the series in that it is not toxic on the healthy cell line and has promising antimicrobial activity.…”
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Development of a broad-spectrum epitope-based vaccine against Streptococcus pneumoniae. by Md Nahian, Muhammad Shahab, Md Rasel Khan, Shopnil Akash, Tanjina Akhtar Banu, Murshed Hasan Sarkar, Barna Goswami, Sanjana Fatema Chowdhury, Mohammad Ariful Islam, Ahmed Abu Rus'd, Shamima Begum, Ahashan Habib, Aftab Ali Shaikh, Jonas Ivan Nobre Oliveira, Shahina Akter

“…The vaccine construct was found to be antigenic, non-toxic, non-allergenic, and soluble. The three-dimensional structure of the vaccine candidate was built and validated. …”
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Removal of copper (II) ions from aqueous solution using acid- and alkali-treated carbonized mangosteen peel as adsorbent by Anee Sweatha, Krishnan Soundarajan

“…The level of toxic heavy metals from the industrial effluents, seeping into neighbouring waterbodies and agricultural land, must be reduced. …”
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СLINICAL AND LABORATORY FEATURES OF LEPTOSPIROSIS DEPENDING ON THE SEASON OF THE YEAR by Olena Zubach, Alexander Zinchuk

“…Jaundice was observed oftenest in patients with leptospirosis during winter, the main complications of leptospirosis (acute kidney failure, toxic shock syndrome and thrombohemorrhagic syndrome) - during the spring months, and pneumonia - in winter. …”
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Curcumin Is an Iconic Ligand for Detecting Environmental Pollutants by T. Devasena, N. Balasubramanian, Natarajan Muninathan, Kuppusamy Baskaran, Shani T. John

“…This review clearly shows that curcumin is an ideal candidate for developing and validating nanomaterials-based sensors for the detection of environmental pollutants such as arsenic, lead, mercury, boron, cyanide, fluoride, nitrophenol, trinitrotoluene, and picric acid and toxic gases such as ammonia and hydrogen chloride. …”
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Discrepancies Between Bayesian Vancomycin Models Can Affect Clinical Decisions in the Critically Ill by Asad E. Patanwala, Danijela Spremo, Minji Jeon, Yann Thoma, Jan-Willem C. Alffenaar, Sophie Stocker

“…AUC24 values were categorized as subtherapeutic (<400 mg·h/L), therapeutic (400–600 mg·h/L), or toxic (>600 mg·h/L), assuming a minimum inhibitory concentration of 1 mg/L. …”
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Histopathological characterization of skin and muscle lesions induced by lionfish (Pterois volitans) venom in a murine experimental model by Cecilia Díaz, Arturo Chang-Castillo, Natalia Ortiz

“…By partial proteomics analysis, we also correlated these in vivo effects with the presence of some potentially toxic venom components. Results: We observed a strong lesion on the skin and evident necrosis in the skeletal muscle. …”
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Evaluation of the Most Current and Effective Methods in the Analysis of Chlorinated Dioxins in Ground Beef by Ebere C. Anyanwu, Mohamed H. El-Saeid, Akpan I. Akpan, Mahmoud A. Saled

“…Chlorinated dioxins are the group of environmental pollutants consisting of 210 chlorinated dibenzo-p-dioxins and dibenzofurans. They are highly toxic and persistent. They are lipophilic and can easily biomagnify in the food chain, hence posing a serious threat to human health. …”
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Clinical-epidemiological study on Fournier's gangrene in a Luanda hospital. From January 2016 to December 2021 by Tomas Ariel Lombardo Vaillant

“…Study variables were: age, toxic habits, comorbidity, clinical manifestations, extension, location as well as its evolution. …”
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Clinically Relevant Drug Interactions with Monoamine Oxidase Inhibitors by Amber N. Edinoff, Connor R. Swinford, Amira S. Odisho, Caroline R. Burroughs, Cain W. Stark, Walid A. Raslan, Elyse M. Cornett, Adam M. Kaye, Alan D. Kaye

“…Under normal conditions, NE is unable to accumulate to toxic levels due to the presence of MAO-A, an enzyme that degrades neurotransmitters, including NE. …”
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Protective effect of nigella sativa and thymoquinone on relative liver weight increase caused by aflatoxin in broilers by Mehmet Burak Ateş, Mustafa Ortatatlı

“…<p> <b>Conclusion:</b> In conclusion, it was thought that TQ and NS prevented the relative liver weight increase, an important biomarker for aflatoxicosis, by probably ameliorating lipid metabolism and transport which is impaired by the toxic effect of AF.…”
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Low-carbon ammonia-based fuel for maritime transport by A.A. Levikhin, A.A. Boryaev

“…Requirements for storage tanks for liquid ammonia and its fire-explosive and toxic properties are also given. Calculated equilibrium values ​​of the energy characteristics of fuels based on liquid ammonia are presented, as well as the results of calculations when using ammonia as a working fluid for electric heating and nuclear rocket engines. …”
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Cytotoxic and Genotoxic Effects of Acephate on Human Sperm by M. A. Thamali Dhanushka, L. Dinithi. C. Peiris

“…Extensive use of organophosphorus pesticides (OPs) could alter semen quality and sperm DNA at different stages of spermatogenesis. Acephate is a highly toxic extensively used OP and, therefore, we aimed to evaluate the effects of acephate on human semen quality and sperm DNA integrity. …”
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