Synthesis of Alkyl α-Amino-benzylphosphinates by the Aza-Pudovik Reaction; The Preparation of the Butyl Phenyl-<i>H</i>-phosphinate Starting P-Reagent by Bence Bajusz, Dorka Nagy, Regina Tóth, Zsuzsanna Szalai, Ágnes Gömöry, Angéla Takács, László Kőhidai, György Keglevich

“…Another derivative, ethyl (α-benzylamino-benzyl-)phenylphosphinate, revealed a selective toxic activity on U266 myeloma cells.…”
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Modified Granular Activated Carbon: A Carrier for the Recovery of Nickel Ions from Aqueous Wastes by D. Satapathy, G.S. Natarajan, Raja Sen

“…Granular Activated Carbon (GAC) is widely used for the removal and recovery of toxic pollutants including metals because of its low cost and high affinity towards the scavenging of metal ions. …”
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The PPAR Ω Pocket: Renewed Opportunities for Drug Development by Åsmund Kaupang, Trond Vidar Hansen

“…The discoveries that lie at the heart of these developments have enabled the design of a new class of PPARγ ligands, capable of isolating central therapeutic effects of PPARγ modulation, while displaying markedly lower toxicities than previous generations of PPARγ ligands. …”
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Kinetics and mechanism of sphalerite leaching by sodium nitrate in sulphuric acid solution by Sokić M., Marković B., Matković V., Živković D., Štrbac N., Stojanović J.

“…Their application provides better metal recoveries and reduced emission of gaseous and toxic ageneses in the environment. The kinetics and mechanism of sphalerite leaching from complex sulphide concentrate with sulphuric acid and sodium nitrate solution at standard conditions was presented in this paper. …”
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Positive sentiment and expertise predict the diffusion of archaeological content on social media by Chiara Bonacchi, Marta Krzyzanska, Alberto Acerbi

“…Our results align with other studies on the spread of misinformation and “toxic” behaviour on social media, showing that the sharing of negative and hostile content by a vocal minority of users is mediated by other factors pertaining to the context of the communication. …”
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On Nonlinear Simulation Methods and Tools for Evaluating the Performance of Ships and Offshore Structures in Waves by Shukui Liu, Apostolos Papanikolaou

“…This capability supports the increased demand of this type of tools for the proper selection of engine/propulsion systems accounting for ship’s performance in realistic sea conditions, or when optimizing ship’s sailing route for minimum fuel consumption and toxic gas emissions.…”
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Opening Doors by Natalie Le Clue

“…Drawing from insights in fan studies, this article explores toxic fan practices within political fandom, as highlighted by Petersen et al. (2023) and Le Clue (2024). …”
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Interplay between porin deficiency, fitness, and virulence in carbapenem-non-susceptible Pseudomonas aeruginosa and Enterobacteriaceae. by Hedi Mammeri, Youssouf Sereme, Eya Toumi, Hélène Faury, David Skurnik

“…Porins are outer membrane proteins, which play a key role in the bacterial permeability to allow nutrients to enter and toxic waste to leave. However, these channels are also "Achilles' heel" of bacteria as antibiotics can also pass through them to reach their target and kill the bacteria. …”
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HIV-Associated Hodgkin's Lymphoma: Prognosis and Therapy in the Era of cART by Caron A. Jacobson, Jeremy S. Abramson

“…Despite these significant advances, HIV-HL patients remain at increased risk for treatment-related toxicities and drug-drug interactions which require careful attention and supportive care to insure the safe administration of therapy. …”
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A Pharmacological and Toxicological Profile of Silver as an Antimicrobial Agent in Medical Devices by Alan B. G. Lansdown

“…Silver sulphide or silver selenide precipitates, bound lysosomally in soft tissues, are inert and not associated with an irreversible toxic change. Argyria and argyrosis are the principle effects associated with heavy deposition of insoluble silver precipitates in the dermis and cornea/conjunctiva. …”
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A Review of Chemical Variability and Metal Contamination of Herbaceous Plants in Terms of Health Safety—A Case Study of <i>Tanacetum vulgare</i> L. by Anna Turek

“…Stress factors to which plants are subjected may result in a decrease in their biological activity or toxic effects (as in the case of <i>Tanacetum vulgare</i> L.). …”
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Transcriptional Regulators of Claudins in Epithelial Tight Junctions by Niamat Khan, Abdul R. Asif

“…Human gastrointestinal tract is covered by a monolayer of specialized epithelial cells that constitute a protective barrier surface to external toxic and infectious agents along with metabolic and digestive functions. …”
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Acute Renal Failure due to a Tobramycin and Vancomycin Spacer in Revision Two-Staged Knee Arthroplasty by Ronak A. Patel, Hayden P. Baker, Sara B. Smith

“…The advantage to this approach is that antibiotic impregnated spacers provide supratherapeutic levels in the joint without toxic accumulation in serum. However, it remains important for physicians and pharmacists to be aware of antibiotic associated complications in knee revisions. …”
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Plasmapheresis for Pembrolizumab-Induced Hepatitis in a Patient with Squamous Cell Carcinoma and Prior Orthotopic Liver Transplantation by Sanaa Al-Nattah, Kusum Lata Sharma, Matthew Caldis, Erin Spengler, William N. Rose

“…Pembrolizumab is one such medication. While severe toxicities are very rare, mild immune-mediated reactions with a variety of end organ injuries are among the most commonly encountered adverse events attributed to these medications. …”
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Genotoxicity Studies of Titanium Dioxide Nanoparticles (TiO2NPs) in the Brain of Mice by Hanan R. H. Mohamed, Nahed A. Hussien

“…Recently, various studies referred to their toxic potential on various organs using different treatment route. …”
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Biochemical analysis to study wild-type and polyglutamine-expanded ATXN3 species. by Grégoire Quinet, María Cristina Paz-Cabrera, Raimundo Freire

“…The main hallmark of SCA3 is the expansion of a polyglutamine tract located in the C-terminal of Ataxin-3 (or ATXN3) protein, that triggers the mis-localization and toxic aggregation of ATXN3 in neuronal cells. The propensity of wild type and polyglutamine-expanded ATXN3 proteins to aggregate has been extensively studied over the last decades. …”
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Recent Updates on Induced Pluripotent Stem Cells in Hematological Disorders by Methichit Wattanapanitch

“…So far, many iPSC-derived disease models have led to the discovery of novel pathological mechanisms as well as new drugs in the pipeline that have been tested in the iPSC-derived cells for efficacy and potential toxicities. Furthermore, recent advances in genome editing technology in combination with the iPSC technology have provided a versatile platform for studying stem cell biology and regenerative medicine. …”
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Das konzeptuelle Potenzial des deutschen Konfixes bio-. Eine korpusbasierte Netzwerkanalyse by Elżbieta Pawlikowska-Asendrych

“…In today’s world, people are aware of the enormous amount of toxic chemical products that many foods contain. …”
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Snus and Health: A Review of the Literature on the Impact of Swedish Smokeless Tobacco on the Human Body by Marta Jajczak, Jakub Parys, Agnieszka Mikosińska, Martyna Kaźmierczak, Aleksandra Witek, Maciej Mossakowski, Patrycja Kałuziak, Mateusz Litwin, Stanisław Jesionek

“…While it does not    cause many of the diseases associated with smoking and the toxic compounds produced during combustion, it is still addictive and contributes to other health issues caused by the substances it contains and the way it is consumed. …”
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Commercial Cannabinoid Oil-Induced Stevens-Johnson Syndrome by Han Y. Yin, Nicholas Hadjokas, Kanish Mirchia, Robert Swan, Samuel Alpert

“…To report an unusual presentation of commercial cannabidiol (CBD) oil-induced Stevens-Johnson Syndrome/toxic epidermal necrolysis (SJS-TEN). Methods. A 56-year-old woman presented with acute onset of a diffuse, blistering, maculopapular rash with over 30% total body surface area (BSA) involvement two days after taking CBD oil sublingually for chronic pain. …”
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