Newer Generation of Scooters: Polychlorinated Dibenzo-p-dioxin and Dibenzofuran and Polychlorinated Biphenyl Reductions by Hung-Hong Chen, Yun-Hwei Shen, Hsi-Hsien Yang, Jau-Huai Lu, Lin-Chi Wang, Yen-Kung Hsieh, Chia-Fon Lee, Sheng-Lun Lin

“…Abstract Scooter emissions have attracted attention in recent years because of human exposure to their direct effects in urban areas. Trace toxics, such as polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) have thus become important in scooter emissions. …”
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Complex immunotoxic effects of T-2 Toxin on the murine spleen and thymus: Oxidative damage, inflammasomes, apoptosis, and immunosuppression by Mingyan Chen, Yanfang Zhang, Yangbo Zhao, Kewei Cao, Ruiyan Niu, Dongguang Guo, Zilong Sun

“…T-2 toxin (T-2), a highly stable and toxic mycotoxin, poses a significant public health risk as an inevitable environmental pollutant. …”
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Antitumor effect of Bothrops jararaca venom by Reinaldo J. da Silva, Márcia G. da Silva, Lízia C. Vilela, Denise Fecchio

“…In vitro treatment with BjV produced a dose-dependent toxic effect on EAT and peritoneal cells, with higher effects against peritoneal cells. …”
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Development and Characterization of Chitosan Nanoparticles Loaded with Amoxicillin as Advanced Drug Delivery Systems against Streptococcus Mutans by Abdullah J Jasem, Maha A Mahmood

“…The resultant nanocomposite can be put to use as an effective, non-toxic antimicrobial agent. CMCS has a considerably wider range of uses as an anti-bacterial agent than chitosan since it is soluble in a wide pH range. …”
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Hypericin-Mediated Photodynamic Therapy for Head and Neck Cancers: A Systematic Review by Jakub Fiegler-Rudol, Natalia Zięba, Radosław Turski, Maciej Misiołek, Rafał Wiench

“…<b>Conclusions</b>: HY-PDT emerges as a highly promising and minimally toxic treatment modality for head and neck cancers, demonstrating efficacy in inducing selective tumour cell death and modulating the immune microenvironment. …”
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Ginkgetin delays the progression of osteoarthritis by inhibiting the NF-κB and MAPK signaling pathways by Liang Zhu, Yanchi Bi, Ting Liang, Po Zhang, Xiao Xiao, Tengbo Yu

“…Ginkgetin (GK), a natural non-toxic chemical, has proven anti-inflammatory, antioxidant, anti-tumor, and neuroprotective effects. …”
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Long-chain chlorinated paraffins (LCCPs) exposure induces apoptosis in primary chicken embryo hepatocytes through oxidative stress by Haochu Deng, Yezi Taishi, Guoxia Wang, Yuebing Kong, Ruoting Zhang, Xin Zheng

“…In conclusion, the current work shows that LCCPs have multiple toxic effects on primary chicken embryo hepatocytes, and lays a theoretical foundation for future research on the harmful effects of LCCPs in the poultry industry.…”
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Comparative efficacy and safety of neoadjuvant radiotherapy for patients with borderline resectable, and locally advanced pancreatic ductal adenocarcinoma: a systematic review and... by Xin Wang, Dan Cao, Qingfeng Wang, Qiancheng Hu, Wanrui Lv

“…Secondary outcomes include overall survival, disease-free survival and acute and late grade 3 and grade 4 toxicities. For randomised control trials, the risk of bias will be assessed using the Cochrane Risk of Bias Tool, while the risk of bias for non-randomised, observational studies will be evaluated using the Risk Of Bias In Non-randomised Studies-of Interventions. …”
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FEATURES OF BIOELEMENTS ACCUMULATION BY FUNGI L. EDODES DURING CULTIVATION IN SUBSTRATES ENRICHED WITH Cr, Se, Ge, Fe CITRATES by I. Andrusyshyna, O. Velikanov, D. Bakhlukov

“…According to the research results, the enrichment of the substrate with citrates Cr, Se, Ge, Fe leads to their accumulation by shiitake mushrooms and also affects the trace element composition of mushrooms in general, but modification of the trace element composition of the substrate does not lead to the accumulation of bioelements and toxicants above the level of the maximum permissible concentration. …”
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Effect of Nigella sativa extract on nasal mucosal inflammation in rats exposed to cigarette smoke by Fathika Alamanda, Anna Mailasari Kusuma Dewi, Dwi Marliyawati, Yanuar Iman Santosa

“…Cigarette smoke contains toxic compounds that can initiate an inflammatory reaction and infiltrate inflammatory cells. …”
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Pain in pancreatitis: issue and ways out by A. V. Okhlobystin

“…Medical treatment of pain includes, first of all, elimination of toxic factors and stimulations of pancreatic secretion. …”
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The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques. by Alexander M Cole, Dorothy L Patton, Lisa C Rohan, Amy L Cole, Yvonne Cosgrove-Sweeney, Nicole A Rogers, Deena Ratner, Alexandra B Sassi, Carol Lackman-Smith, Patrick Tarwater, Bharat Ramratnam, Piotr Ruchala, Robert I Lehrer, Alan J Waring, Phalguni Gupta

“…<h4>Background</h4>RC-101 is a congener of the antiretroviral peptide retrocyclin, which we and others have reported is active against clinical HIV-1 isolates from all major clades, does not hemagglutinate, and is non-toxic and non-inflammatory in cervicovaginal cell culture. …”
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Release of tumour necrosis factor alpha into bronchial alveolar lavage fluid following antigen challenge in passively sensitized guinea-pigs by D. E. Kelly, M. Denis, D. F. Biggs

“…BAL fluid from OA sensitized animals that inhaled OA aerosols contained no detectable TNF-α at 30 min, but it was found in increasing amounts at 60, 90 and 120 min; TNF-α was not detected in fluid from any of the animals that inhaled saline. As BAL fluids were toxic to the cells used in the assays, neither IL-1 nor IL-6 could be measured. …”
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Ecological and genetic assessment of the consequences of radiation influence on contaminated areas by A. B. Bigaliev, K. Z. Shalabaeva, B. E. Shimshikov, S. S. Kobegenova, L. M. Adilova, A. N. Kozhakhmetova, S. Sharakhmetov, M. N. Burkhanova

“…A reconnaissance and radioecological examination of environmental objects was carried out using analytical methods, which made it possible to determine the quantitative content of toxic components, the content of priority pollutants and radioactive isotopes. …”
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The evolving roles of geophysics in environmental assessment, monitoring, and management of landfill leachate contaminant plumes: An overview by Joseph Omeiza Alao

“…Landfill leachate, a toxic brew of pollutants, poses a silent threat to water resources, ecosystems, and public health. …”
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Therapeutic Effects of the Combination of Alpha-Lipoic Acid (ALA) and Coenzyme Q10 (CoQ10) on Cisplatin-Induced Nephrotoxicity by Eman Aly Khalifa, Ahmed Nabil Ahmed, Khalid Shaaban Hashem, Ahmad Gad Allah

“…However, despite intense efforts to develop less toxic and equally effective alternatives, cisplatin continues to be widely prescribed. …”
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Evaluation of the cardiotoxicity of Echinochrome A using human induced pluripotent stem cell-derived cardiac organoids by Su-Jin Lee, Eunji Kim, Yeeun Jeong, Jae Boum Youm, Hyoung Kyu Kim, Jin Han, Elena A. Vasileva, Natalia P. Mishchenko, Sergey A. Fedoreyev, Valentin A. Stonik, Sung Joon Kim, Hyang-Ae Lee

“…EchA treatment induced no significant changes in these parameters, confirming its non-toxic electrophysiological profile. Cellular viability and lactate dehydrogenase (LDH) assays revealed no cytotoxic effects of EchA across tested concentrations. …”
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Associations of prenatal urinary melamine, melamine analogues, and aromatic amines with gestational duration and fetal growth in the ECHO Cohort by Giehae Choi, Xiaoshuang Xun, Deborah H. Bennett, John D. Meeker, Rachel Morello-Frosch, Sheela Sathyanarayana, Susan L Schantz, Leonardo Trasande, Deborah Watkins, Edo D. Pellizzari, Wenlong Li, Kurunthachalam Kannan, Tracey J. Woodruff, Jessie P. Buckley

“…While these chemicals have identified toxicities, little is known about their influences on fetal development. …”
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Total flavonoids isolated from Eucommia ulmoides can alleviate bone loss and regulate intestinal microbiota in ovariectomized rats by Baocang Yin, Baocang Yin, Mingzhen Yang, Mingzhen Yang, Bowen Wang, Bowen Wang, Yun Zhang, Yun Zhang, Ningli Li, Ningli Li, Qin Li, Yingying Li, Cory J. Xian, Tiejun Li, Tiejun Li, Yuankun Zhai, Yuankun Zhai

“…High-throughput sequencing indicated that TFEL may regulate the composition of intestinal flora and intestinal microecology.ConclusionTFEL can prevent osteoporosis in OVX rats and has no toxic side effects. Meanwhile, TFEL can increase the diversity and improve the composition of intestinal flora in OVX rats.…”
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Sodium arsenite induces islets β-cells apoptosis and dysfunction via SET-Rac1-mediated cytoskeleton disturbance by Tianming Qiu, Yu Zhi, Jingyuan Zhang, Ningning Wang, Xiaofeng Yao, Guang Yang, Liping Jiang, Li Lv, Xiance Sun

“…This discovery could provide novel insights into therapeutic strategies for T2D provoked by environmental toxicants.…”
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