Ammonium Ion Exchanged Zeolite for Laser Desorption/Ionization Mass Spectrometry of Phosphorylated Peptides by Mengrui Yang, Tatsuya Fujino

“…CHCA adsorbed to NH4+-type ZSM5 zeolite (CHCA/NH4ZSM5) was used to measure atropine and aconitine, two toxic alkaloids in plants. In addition, CHCA/NH4ZSM5 enabled us to detect phosphorylated peptides; peaks of the protonated peptides had higher intensities than the peaks observed using CHCA only.…”
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Venom of the Endoparasitoid Wasp Pteromalus puparum: An Overview by Jia-Ying Zhu, Gong-Yin Ye, Cui Hu

“…Even great achievements have been made, further research is required to uncover the sophisticated bioactivity of the venom and isolate more novel toxic peptides/proteins.…”
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Epidermal Growth Factor Receptor Gene in Non-Small-Cell Lung Cancer: The Importance of Promoter Polymorphism Investigation by Vladimir Jurišić, Jasmina Obradovic, Sonja Pavlović, Nataša Djordjevic

“…The accumulation of knowledge regarding SNPs lately suggests their significant and important role in the onset of carcinogenesis, the prediction of the onset of metastases, the response to therapy with TKI inhibitors, and the onset of toxic effects of the applied therapy. Based on this, we suggest further studies of the relationship of clinical significance to SNPs in patients with lung tumors.…”
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Immunotherapy in the Treatment of Metastatic Melanoma: Current Knowledge and Future Directions by Massimo Ralli, Andrea Botticelli, Irene Claudia Visconti, Diletta Angeletti, Marco Fiore, Paolo Marchetti, Alessandro Lambiase, Marco de Vincentiis, Antonio Greco

“…Immunotherapy is associated to a panel of dysimmune toxicities called immune-related adverse events that can affect one or more organs and may limit its use. …”
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Biosorption of Copper Ions by and Species by Sara Ghaed, Elham Khalilzadeh Shirazi, Reza Marandi

“…Compared with other alternatives, these metabolically inactive and nonliving biomasses of microbial or floral origins are cheaper and more effective in removing metallic elements, some of which are toxic and carcinogenic. The discharge of heavy metals, such as copper ions into wastewater is regarded as a serious threat to the environment. …”
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Research Progress on the Preparation, Physiological Activity and Action Mechanism of Plant Derived Bioactive Peptides by Sinan LI, Xi WANG, Yu AN, Jun YU, Kaiyuan XU, Jia WANG, Zhihui ZHANG, Meng WANG, Aqin WANG, Ying WANG, Lu ZHANG

“…Plant-derived BAPs come from a wide range of sources, are safe and non-toxic. At present, a large number of plant-derived BAPs have been identified by isolation and purification. …”
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Crystal structure and Hirshfeld surface analysis of the layered hybrid metal halide poly[bis(2-iodoethylammonium) [di-μ-iodido-diiodidogermanate(II)]] by Olesia I. Kucheriv, Mircea-Odin Apostu, Olena Prysiazhna, Vadim A. Potaskalov, Sergey O. Malinkin

“…The title compound is a germanium-based hybrid metal halide that represents a less-toxic alternative to more popular lead-based analogues in optoelectronic applications. {(2-IC2H4NH3)2[GeI4]}n is composed of infinite inorganic layers that are formed by [GeI6]4− octahedra connected in a corner-sharing manner with four equatorial I atoms. …”
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Different Genotypes of the Rare and Threatened Moss <i>Physcomitrium eurystomum</i> (Funariaceae) Exhibit Different Resilience to Zinc and Copper Stress by Djordje P. Božović, Marija V. Ćosić, Vladislav Kolarčik, Michal Goga, Claudio Varotto, Mingai Li, Aneta D. Sabovljević, Marko S. Sabovljević

“…The riparian habitat type of this species is often under the influence of contaminated water, and, therefore, we tested the influence of selected potentially toxic elements (PTEs), namely zinc and copper, on the development, physiological features, and survival of the species on two different accessions (German and Croatian). …”
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Mechanisms of Alcohol-Induced Endoplasmic Reticulum Stress and Organ Injuries by Cheng Ji

“…Potential mechanisms that trigger the alcoholic ER stress response are directly or indirectly related to alcohol metabolism, which includes toxic acetaldehyde and homocysteine, oxidative stress, perturbations of calcium or iron homeostasis, alterations of S-adenosylmethionine to S-adenosylhomocysteine ratio, and abnormal epigenetic modifications. …”
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Current Pharmacologic Approaches for Prevention and Treatment of Bronchopulmonary Dysplasia by Kristen Tropea, Helen Christou

“…Contributing factors include ventilator-induced lung injury, exposure to toxic oxygen levels, and infection. Several preventive and therapeutic strategies have been developed with variable success. …”
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An Episode of Pseudothrombocytopenia during Pembrolizumab Therapy in NSCLC Patient by Kinga Krukowska, Robert Kieszko, Katarzyna Kurek, Izabela Chmielewska, Paweł Krawczyk, Janusz Milanowski

“…In addition to an antitumor effect, ICI are associated with autoimmune reactions resulting in a wide spectrum of toxicities that have not been seen in patients receiving chemotherapy. …”
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Effect of Monotherapy and Combination Therapy of Pantoprazole and Aprepitant in Gastric Esophageal Reflux Disease in Albino Rats by Kamleshwar Shukla, Prince Raj, Arun Kumar, Mukesh Kumar, Gaurav Kaithwas

“…Groups of rats, fasted overnight, received normal saline (3 mL/kg, sham control) or toxic control (3 mL/kg) or pantoprazole (30 mg/kg) or aprepitant (10 mg/kg), or their combinations and were subjected to pylorus and forestomach ligation. …”
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Real-World Experience with Dolutegravir-Based Two-Drug Regimens by Douglas Ward, Moti Ramgopal, David J. Riedel, Cindy Garris, Shelly Dhir, John Waller, Jenna Roberts, Katie Mycock, Alan Oglesby, Bonnie Collins, Megan Dominguez, James Pike, Joseph Mrus

“…The most common physician-reported reasons for initiating DTG 2DR were treatment simplification/streamlining (30%) and avoidance of potential long-term toxicities (20%). Before starting DTG 2DR, 42% of patients were virologically suppressed; of those, 95% maintained suppression while on DTG 2DR. …”
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Bioinorganic Synthesis of Polyrhodanine Stabilized Fe3O4/Graphene Oxide in Microbial Supernatant Media for Anticancer and Antibacterial Applications by Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Ahmad Gholami, Navid Omidifar, Maryam Zarei, Sonia Bahrani, Khadije Yousefi, Wei-Hung Chiang, Aziz Babapoor

“…Consequently, based on the results, it can be concluded that this novel polyrhodanine-based nanocompound can act as drug carriers due to their low toxic effects and may open a new window on the antibacterial agents.…”
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Low dose DNA methyltransferase inhibitors potentiate PARP inhibitors in homologous recombination repair deficient tumors by Romain Pacaud, Scott Thomas, Sibapriya Chaudhuri, Ann Lazar, Luika A. Timmerman, Pamela N. Munster

“…However, clinical responses are often not durable and treatment may be detrimental in advanced cancer due to excessive toxicities. Thus we are seeking alternative therapeutics to enhance PARP-directed outcomes. …”
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Fast and Slow Roasting of Alcohol- and Honey-infused Coffee Blends: A Comparative Study of PAH and N-PAH Emissions by Hsin-Chieh Kung, Chung-Hsien Hung, Kun-Hui Lin, Bo-Wun Huang, Nicholas Kiprotich Cheruiyot, Guo-Ping Chang-Chien

“…The fast roasting of green coffee resulted in mass and toxic concentrations approximately 1.6 and 3.2 times higher than in the slow roasting method (5,069 ng Nm−3 and 14.1 ng BaP-TEQ Nm−3, respectively). …”
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Imprint of ancestral and modern threats in human mind – experience of fear, disgust, and anger by Eva Landová, Eva Landová, Jakub Polák, Jakub Polák, Markéta Janovcová, Iveta Štolhoferová, Šárka Peterková, Aleksandra Chomik, Daniel Frynta

“…Disgust does not respond to modern threat stimuli such as toxic substances or radioactivity as these evoke mainly fear and anger. …”
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Motion Trajectory Planning and Design of Material Spraying Service Robot by Gang Wang, Hongyuan Wen, Jun Feng, Jun Zhou

“…The application of robots reduces repetitive and dangerous tasks for humans, especially the spraying robot, because many spraying materials are corrosive, toxic, and harmful. This paper designs the motion trajectory planning of the material spraying service robot. …”
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Viral Response to Specifically Targeted Antiviral Therapy for Hepatitis C and the Implications for Treatment Success by Curtis L Cooper

“…The attrition rate of agents within this class has been high due to various toxicities. Regardless, several STAT-C molecules are poised to become the standard of care for HCV treatment in the foreseeable future. …”
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Treatments for Severe Cutaneous Adverse Reactions by Yung-Tsu Cho, Chia-Yu Chu

“…It consists of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), drug reaction with eosinophilia and systemic symptoms (DRESS), acute generalized exanthematous pustulosis (AGEP), and generalized bullous fixed drug eruptions (GBFDE). …”
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