An Updated Review of the Molecular Mechanisms in Drug Hypersensitivity by Chun-Bing Chen, Riichiro Abe, Ren-You Pan, Chuang-Wei Wang, Shuen-Iu Hung, Yi-Giien Tsai, Wen-Hung Chung

“…., maculopapular exanthema and urticaria) to severe systemic reactions, such as anaphylaxis, drug reactions with eosinophilia and systemic symptoms (DRESS)/drug-induced hypersensitivity syndrome (DIHS), or Stevens–Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN). Current pharmacogenomic studies have made important strides in the prevention of some drug hypersensitivity through the identification of relevant genetic variants, particularly for genes encoding drug-metabolizing enzymes and human leukocyte antigens (HLAs). …”
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Soil Assessment along Toposequences in Rural Northern Nigeria: A Geomedical Approach by Lena Hartmann, Marvin Gabriel, Yuanrong Zhou, Barbara Sponholz, Heinrich Thiemeyer

“…Case numbers of endemic Ca-deficiency rickets (CDR) have been reported to be alarmingly rising among children of subsistence farms in developing countries within the last 30 years. Fluoride toxicities in the environment are known to not be related to the disease. …”
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The Current Status of Atmospheric Micro/Nanoplastics Research: Characterization, Analytical Methods, Fate, and Human Health Risk by Hsin-Chieh Kung, Chien-Hsing Wu, Nicholas Kiprotich Cheruiyot, Justus Kavita Mutuku, Bo-Wun Huang, Guo-Ping Chang-Chien

“…Since most polymers are inert, the adverse health risks include endocytosis and accumulation in the liver and spleen. However, most of the toxic effects of these contaminants are related to surface-bound compounds, including heavy metals and persistent organic pollutants. …”
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Methane detection approach based on THz wave absorber by Alireza Barati Haghverdi, Ilghar Rezaei, Amir Ali Mohammad Khani, Toktam Aghaee

“…The second scenario considers the sample (probably toxic polluted air) in the middle layer and also in free space. …”
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Identification of plastic waste generation and composition to reduce environmental disaster risk (case study: Public facility sources in Padang City) by Ruslinda Yenni, Fahrunisa Gebi, Ayu Lestari Resti, Gunawan Hendra, Amin Muhammad

“…The degradation of plastic waste in aquatic environments can result in microplastics that threaten marine life, while the incineration of plastic waste produces toxic gases harmful to health. This study aims to identify the generation and composition of plastic waste as an initial step in reducing environmental disaster risks. …”
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Simultaneous Determination of Cr, As, Se, and Other Trace Metal Elements in Seawater by ICP-MS with Hybrid Simultaneous Preconcentration Combining Iron Hydroxide Coprecipitation an... by Akihide Itoh, Masato Ono, Kota Suzuki, Takumi Yasuda, Kazuhiko Nakano, Kimika Kaneshima, Kazuho Inaba

“…Nevertheless, the present method would have possibility to develop as the analytical method to determine comprehensively most metal elements in all standard and guideline values in quality standard in environmental water in Japan, that is, most toxic metal elements in environmental water.…”
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Aflatoxin B1 impairs the growth and development of chicken PGCs through oxidative stress and mitochondrial dysfunction by Ying-Jie Niu, Jun Wu, Wenjie Ren, Guangzheng Liu, Gaoyuan Wu, Yixiu Peng, Dan Zheng, Kai Jin, Qisheng Zuo, Guohui Li, Wei Han, Xiang-Shun Cui, Guohong Chen, Bichun Li

“…This study illuminates AFB1's toxic effects on chicken PGCs and provides insights into potential mechanisms, establishing a basis for strategies to prevent and treat AFB1's adverse effects on poultry genetic transmission.…”
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Atmospheric pressure plasma synthesis of adaptable coatings based on castor oil urethane dimethacrylate and their properties by Eusebiu-Rosini Ionita, Maria-Daniela Ionita, Antoniu Moldovan, Cristina Surdu-Bob, Violeta Melinte, Andreea L. Chibac-Scutaru, Andrada Lazea-Stoyanova

“…In short, our plasma-based method for generation of CO-PMA layers, in dynamic mode, does not require toxic photoinitiators, is simple, can be applied to temperature-sensitive materials and is scalable to large areas.…”
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Selecting first-line immunotherapy in advanced melanoma: Current evidence on efficacy across diverse patient populations by Sophia Kreft, Tommaso Bosetti, Rebecca Lee, Paul Lorigan

“…Since most patients who respond to combination ipilimumab-nivolumab also respond to nivolumab-relatlimab, and many to single-agent anti-programmed death-1 (PD-1) monotherapy, the challenge is to identify the subgroup of patients who need ipilimumab-nivolumab and would not achieve similar benefits from less toxic alternatives. This review discusses the available data on efficacy of the three approved first-line immunotherapies (single-agent anti-PD-1, nivolumab-relatlimab or ipilimumab-nivolumab) and their value in distinct population groups to help guide clinical decisions.…”
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Micromorphological and Chemical Approaches to Understand Changes in Ecological Functions of Metal-Impacted Soils under Various Land Uses by J. A. Acosta, S. Martinez-Martinez, A. Faz, J. M. Van Mourik, J. M. Arocena

“…We investigated the changes in faunal activities as measures of the ecological functions of soils impacted by potentially toxic metals (PTMs) under urban, industrial, agricultural, and natural uses. …”
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Present Status of Ganges River Dolphins Platanista gangetica gangetica (Roxburgh, 1801) in the Turag River, Dhaka, Bangladesh by Mohammad Abdul Baki, Naser Ahmed Bhouiyan, Md. Saiful Islam, Shayer Mahmood Ibney Alam, Shibananda Shil, Md. Muzammel Hossain

“…Freshwater ecosystem degradation in the Turag River basin is increasing due to rising human settlement, reduced water flow during the dry season, new large land development projects, and toxic emissions caused by brick kilns. The population of river dolphins was estimated through surveys carried out from December 2012 to November 2013. …”
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Utilization Patterns and Projected Demand of Antiretroviral Drugs in Low- and Middle-Income Countries by Françoise Renaud-Théry, Carlos Avila-Figueroa, John Stover, Sigrid Thierry, Marco Vitoria, Vincent Habiyambere, Yves Souteyrand

“…Despite the global economic crisis and in response to the revised treatment guidelines, our model forecasts an increasing and shifting demand for antiretrovirals in resource-limited settings not only to provide treatment to new patients, but also to those switching to less toxic regimens.…”
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Copper strontium phosphate glasses with high antimicrobial efficacy by Roman Golovchak, Bohdan Mahlovanyi, Yaroslav Shpotyuk, Malgorzata Kus-Liskiewicz, Julia Kozianska, Renata Zadrag-Tecza, Grzegorz Zagula, Malgorzata Trzyna-Sowa, Andriy Kovalskiy, Agnieszka Gala-Bladzinska, Jozef Cebulski

“…Bulk surfaces of these glasses inhibit bacterial growth and release low, non-toxic levels of their constituent elements into simulated body fluid. …”
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QD/SnO₂ Photoactivated Chemoresistive Sensor for Selective Detection of Primary Alcohols at Room Temperature by Maria Yu. Skrypnik, Vadim B. Platonov, Daria A. Kurtina, Oleg G. Sinyashin, Marina N. Rumyantseva, Roman B. Vasiliev

“…Sensors based on nanocomposites of quantum dots (QDs) and wide-gap metal oxides are of exceptional interest for photoactivated detection of toxic and pollutant gases without thermal heating. …”
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Inhibition Behavior of PCDD/Fs Congeners by Addition of N-containing Compound in the Iron Ore Sintering by Yifan Wang, Lixin Qian, Zhengwei Yu, Tiejun Chun, Hongming Long, Xuejian Wu, Jiaxin Li

“…Abstract PCDD/Fs are typical toxic persistent aromatic compounds that greatly reduce air quality and harm human health. …”
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High-Titer L-lactic Acid Production by Fed-Batch Simultaneous Saccharification and Fermentation of Steam-Exploded Corn Stover by Liheng Deng, Changsheng Su, Yilu Wu, Qiang Xue, Changwei Zhang, Yong Wang, Bin Wang, Di Cai

“…The results indicated that the fed-batch SSF, with a simple pH control, realized a higher tolerance of the strains to the toxic by-products of hydrolysate, in comparison to the conventional sequential hydrolysis and fermentation (SHF), allowing for 153.8 g L⁻¹ of L-LA production, along with a productivity of 1.83 g L⁻¹ h⁻¹ in a system with a total of 40% (<i>w</i>/<i>v</i>) solid loading. …”
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Development of a New Sequential Extraction Procedure of Nickel Species on Workplace Airborne Particulate Matter: Assessing the Occupational Exposure to Carcinogenic Metal Species by Catalani Simona, Fostinelli Jacopo, Gilberti Maria Enrica, Orlandi Francesca, Magarini Riccardo, Paganelli Matteo, Madeo Egidio, De Palma Giuseppe

“…The method has occurred effectively in the comparison of the obtained results with occupational exposure limit values set by the main international scientific and regulatory agencies for occupational safety and health, in order to prevent both toxic and carcinogenic effects in humans.…”
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Thermal Treatment of Cerium Oxide and Its Properties: Adsorption Ability versus Degradation Efficiency by Pavel Janoš, Tomáš Hladík, Martin Kormunda, Jakub Ederer, Martin Šťastný

“…Cerium oxide belongs to the most important heterogeneous catalysts, but its applicability as so-called reactive sorbent for the degradation of toxic chemicals was only recently discovered. For these purposes, cerium oxide is prepared by precipitation of insoluble cerium salts (carbonates) with a subsequent thermal decomposition. …”
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Computational evaluation on spectroscopic (FT-IR, Raman), electronic and biological, and NLO properties of cirsilineol by DFT, ADMET, and molecular docking method by Tirth Raj Paneru, Poonam Tandon, Bhawani Datt Joshi

“…The pharmacological properties of cirsilineol determined by ADMED analysis confirmed that it is non-toxic. To assess the biological performance of cirsilineol, molecular docking was performed with protein codes 1E3G and 1GS4, which showed inhibition action with binding affinity −7.7 and −7.8 kcal/mol, respectively. …”
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Computational evaluation on spectroscopic (FT-IR, Raman), electronic and biological, and NLO properties of cirsilineol by DFT, ADMET, and molecular docking method by Tirth Raj Paneru, Poonam Tandon, Bhawani Datt Joshi

“…The pharmacological properties of cirsilineol determined by ADMED analysis confirmed that it is non-toxic. To assess the biological performance of cirsilineol, molecular docking was performed with protein codes 1E3G and 1GS4, which showed inhibition action with binding affinity −7.7 and −7.8 kcal/mol, respectively. …”
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