Proteostasis and Mitochondrial Role on Psychiatric and Neurodegenerative Disorders: Current Perspectives by Pablo Olivero, Carlo Lozano, Ramón Sotomayor-Zárate, Nicolás Meza-Concha, Marcelo Arancibia, Claudio Córdova, Wilfredo González-Arriagada, Ricardo Ramírez-Barrantes, Ivanny Marchant

“…Thus, protein misfolding and the formation of toxic aggregates at neural level, secondary to dysregulation of the conservative mechanisms of proteostasis, are associated with several neuropsychiatric conditions. …”
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Alternative 3′ UTR polyadenylation is disrupted in the rNLS8 mouse model of ALS/FTLD by Randall J. Eck, Paul N. Valdmanis, Nicole F. Liachko, Brian C. Kraemer

“…Together, these findings support both TDP-43 loss and toxic gain-of-function phenotypes as contributors to the neurodegeneration in rNLS8 mice, nominating its continued utility as a preclinical model for investigating mechanisms of neurodegeneration in ALS/FTLD-TDP.…”
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Contribution of Lung Macrophages to the Inflammatory Responses Induced by Exposure to Air Pollutants by Kunihiko Hiraiwa, Stephan F. van Eeden

“…Large population cohort studies have indicated an association between exposure to particulate matter and cardiopulmonary morbidity and mortality. The inhalation of toxic environmental particles and gases impacts the innate and adaptive defense systems of the lung. …”
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Sustainable Development of Corrosion Inhibitors from Electronic Scrap: Synthesis and Electrochemical Performance by J. Porcayo-Calderon, J.J. Ramos-Hernandez, E. Porcayo-Palafox, L.M. Martínez de la Escalera, J. Canto, J.G. Gonzalez-Rodriguez, L. Martinez-Gomez

“…Due to its high content of rare earths, the use of permanent magnets can be a sustainable alternative for the synthesis of environmentally friendly corrosion inhibitors in order to replace the use of highly toxic inhibitors, as well as the use of rare earth salts of high purity and high cost. …”
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Dynamics of a Breast Cancer Model for Neutropenia Case due to Chemotherapy Effects by M. Ivan Ariful Fathoni, Fajar Adi-Kusumo, Gunardi Gunardi, Susanna Hilda Hutajulu

“…Chemotherapy-induced neutropenia is one of the most common toxic effects experienced by patients and often threatens chemotherapy to use efficiency. …”
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Polydiacetylene (PDA) Embedded Polymer-Based Network Structure for Biosensor Applications by Huisoo Jang, Junhyeon Jeon, Mingyeong Shin, Geonha Kang, Hyunil Ryu, Sun Min Kim, Tae-Joon Jeon

“…This color change enables the detection of biomarkers, metal ions, and toxic compounds. Moreover, the combination of PDA with polymeric structures including hydrogels further enhances the sensitivity and structural stability of PDA-based biosensors, making them reliable and effective in complex biological and environmental conditions. …”
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Partial Purification and Characterization of Rhodanese from Rainbow Trout (Oncorhynchus mykiss) Liver by Hossein Tayefi-Nasrabadi, Reza Rahmani

“…Cyanide is one of the most toxic substances present in a wide variety of food materials that are consumed by animals. …”
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Facile synthesis of mesoporous alumina using hexadecyltrimethylammonium bromide (HTAB) as template: simplified sol‐gel approach by Sameer H. Lakade, Minal T. Harde, Varsha Chattichalwadi, Pravin S. Uttekar

“…The IC50 value obtained from cell viability study demonstrated the non‐toxic behaviour of synthesised drug‐loaded mesoporous alumina up to the tested concentration range. …”
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A review on perovskite materials for photovoltaic applications by Lalruat Sanga, Celestine Lalengmawia, Zosiamliana Renthlei, Sougaijam Thasana Chanu, Lalhum Hima, Ningthoujam Surajkumar Singh, Andre Yvaz, Sagar Bhattarai, D.P. Rai

“…However, as the reason of their instability in its structure and the presence of toxic elements like lead element (Pb), the performance of these materials has been hindering the production and successful manufacturing of perovskite solar cells (PSCs) at the commercial level. …”
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Markers of Inflammation and Fibrosis in Alcoholic Hepatitis and Viral Hepatitis C by Manuela G. Neuman, Hemda Schmilovitz-Weiss, Nir Hilzenrat, Marc Bourliere, Patrick Marcellin, Cristhian Trepo, Tony Mazulli, George Moussa, Ankit Patel, Asad A. Baig, Lawrence Cohen

“…Proinflammatory cytokines’ responses to viral and/or toxic injury differed with the severity of liver inflammation. …”
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Thyroid Hemiagenesis Associated with Hyperthyroidism by Gunay Gurleyik, Emin Gurleyik

“…Nuclear scan, confirming absence of the left lobe, showed hot nodules in the right one. The diagnosis was toxic multinodular goitre. Case Two. The thyroid was not palpable in this patient presented with signs and symptoms of thyrotoxicosis. …”
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General Phenotype of NADase Induction by CLI Treatment in Streptococcus pyogenes by Ichiro Tatsuno, Masanori Isaka, Tadao Hasegawa

“…The administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic-shock syndrome (STSS). However, we previously reported that a “subinhibitory dose” of CLI induced the expression of the NAD-glycohydrolase (NADase) exotoxin in an emm1-type Streptococcus pyogenes 1529 strain isolated from an STSS patient. …”
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Mobility of Iron-Cyanide Complexes in a Humic Topsoil under Varying Redox Conditions by Thilo Rennert, Tim Mansfeldt

“…The potentially toxic Fe-CN complexes ferricyanide, [FeIII(CN)6]3−, and ferrocyanide, [FeII(CN)6]4−, undergo a variety of redox processes in soil, which affect their mobility. …”
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Mycotoxins and Antifungal Drug Interactions: Implications in the Treatment of Illnesses Due to Indoor Chronic Toxigenic Mold Exposures by Ebere C. Anyanwu, Andrew W. Campbell, John E. Ehiri

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Variant Guillain-Barré Syndrome in a Patient with Non-Hodgkin’s Lymphoma by R. H. Bishay, J. Paton, V. Abraham

“…Previous reports have largely focused on toxicities secondary to chemo- or radiotherapy as a major contributor to the development of acute neuropathies in malignancy. …”
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Immunohistopathological Findings of Severe Cutaneous Adverse Drug Reactions by Mari Orime

“…The characteristic histological findings of erythema multiforme (EM), Stevens–Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) provide conclusive evidence demonstrating that SJS/TEN can be distinguished from EM. …”
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Lamotrigine-Related Skin Rash by J. Jokubaitė, L. Martinėlė, G. Joskaudaitė, T. Raudonis

“… Antiepileptic drugs can cause a variety of adverse skin reactions, from mild and transient maculopapular rash to severe and life-threatening reactions such as Stevens-Johnson syndrome or even toxic epidermal necrolysis. Lamotrigine is a new-generation aromatic antiepileptic drug whose effectiveness has been observed not only in the treatment of epilepsy but also in other disorders, such as bipolar disorder. …”
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Therapy of Inflammatory Bowel Disease using New 5-ASA Compounds: An Introduction by Ulrich Klotz

“…Since the active metabolite avoids the toxic potential of sulphapyridine, this perception has initiated new therapeutic approaches, for example, two 5-ASA molecules have been coupled to form another prodrug (olsalazine) which again depends on a proper cleavage of the azobond by bacteria in the colon A more direct way has been applied successfully by administering 5-ASA itself in special galenic formulation (suppositories, enemas, controlled release preparations) to provide enough active material at the proposed sites of action in the terminal ileum and/or colon. …”
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The Key to Unlocking the Chemotherapeutic Potential of PPARγ Ligands: Having the Right Combination by Graham Skelhorne-Gross, Christopher J. B. Nicol

“…There are also studies that indicate that PPARγ ligand pretreatment overcomes resistance and reduces toxicities. Several mechanisms are explored to explain these protective effects. …”
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Infertility in Men with Spinal Cord Injury: Research and Treatment by Nancy L. Brackett

“…Most men with SCI have a unique semen profile characterized by normal sperm concentration, but abnormally low sperm motility. Toxic substances in the semen contribute to this problem. …”
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