Staying Optimistic: The Trials and Tribulations of Leibnizian Optimism by Lloyd Strickland

“…As we shall see, while Leibniz’s doctrine did win a good number of adherents in the 1720s and 1730s, especially in Germany, support for it had largely dried up by the mid-1740s; moreover, while opponents of Leibniz’s doctrine were few and far between in the 1710s and 1720s, they became increasing vocal in the 1730s and afterwards, between them producing an array of objections that served to make Leibnizian optimism both philosophically and theologically toxic years before the Lisbon earthquake struck.…”
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Adsorption Characteristics of Acid Orange 10 from Aqueous Solutions onto Montmorillonite Clay by Manpreet Kaur, Monika Datta

“…Azo dyes have been identified as the most toxic of all dyes since they may be converted into potentially carcinogenic and/or mutagenic amines as a result of the reductive cleavage of the azo linkages after being released into the aquatic environment. …”
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Contaminants in the Urban Environment: Pharmaceuticals and Personal Care Products (PPCPs)—Part 1 by Yun-Ya Yang, Gurpal S. Toor

“…This series is intended to give state and local government officials, soil scientists, consulting engineers, extension agents, and citizens (1) a basic understanding of the occurrence, toxic effects, and source of various contaminants in the environment and (2) guidance on ways to protect human and environmental health. …”
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Successful Renal Transplantation between Identical Twins with Very Brief Immunosuppression by Idris Yakubu, Abdolreza Haririan, Stephen Bartlett, Tracy Sparkes

“…Renal transplantation between monozygous identical twins provides an opportunity to utilize minimal immunosuppression to maintain stable allograft function, thereby alleviating the toxicities of immunosuppressive therapy. Despite monozygosity, there is a possibility of discordant protein presentation in identical twins that could trigger alloimmune response and lead to graft injury. …”
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Antibiotic Treatment of Dogs and Cats during Pregnancy by Marcela Rebuelto, María Elena Loza

“…The risk to the fetus is a result of the ability of a drug to reach the fetal circulation and to produce toxic effects. The placenta functions as a barrier that protects the fetus due to the presence of transporters and metabolising enzymes; however, during pregnancy, the presence and activity of both enzymes and transporters may change. …”
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A Beginner’s Guide to Water Management—Fish Kills by Florida LAKEWATCH

“… In an effort to alleviate concerns voiced by the general public, the Florida LAKEWATCH (FLW) program published this 16-page booklet that discusses five of the most common natural causes of fish kills including: low dissolved oxygen; spawning fatalities; mortality due to cold temperatures; diseases and parasites; and toxic algae blooms. Human-induced fish kills are also covered along with a section on fish stress—a component of virtually every fish kill situation. …”
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Simultaneously Recovering High-Purity Chromium and Removing Organic Pollutants from Tannery Effluent by Jie Zong, Yan-Chun Li, Kang Hu

“…Chromium pollution is a serious issue because of carcinogenic toxicities of the pollutants and low recovery rate of chromium because of the presence of organic, such as protein and fat. …”
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Blowout Accident Impact Analysis Method for the Siting of Offshore Floating Nuclear Power Plant in Offshore Oil Fields by Zhigang Lan

“…The impacts of blowout accident in offshore oil field on OFNPP are comprehensively analyzed, including injection combustion and spilled oil combustion induced by well blowout, drifting and explosion of deflagration vapor clouds formed by well blowouts, seawater pollution caused by blowout oil spills, the toxic gas cloud caused by well blowout, and the impact of mobile fire source formed by a burning oil spill on OFNPP at sea. …”
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Recent advances in the characterization of genetically defined neurons that regulate internal‐state‐dependent taste modification in mice by Ken‐ichiro Nakajima

“…While some tastes are intrinsically appetitive, such as sweet, which is elicited from high‐calorie nutrients, the other tastes, such as sour and bitter, are aversive and elicited by toxic substances. In mice, taste signals are relayed by multiple regions of the brain, including the nucleus of the solitary tract, and the parabrachial nucleus (PBN) of the pons, before reaching the gustatory cortex via the gustatory thalamus. …”
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A Beginner’s Guide to Water Management—Fish Kills by Florida LAKEWATCH

“… In an effort to alleviate concerns voiced by the general public, the Florida LAKEWATCH (FLW) program published this 16-page booklet that discusses five of the most common natural causes of fish kills including: low dissolved oxygen; spawning fatalities; mortality due to cold temperatures; diseases and parasites; and toxic algae blooms. Human-induced fish kills are also covered along with a section on fish stress—a component of virtually every fish kill situation. …”
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Privatized Futures, Climate Control, and Resistance in Recent Scottish Dystopian Fiction by Peter Clandfield

“…After discussing Alasdair Gray’s 1982, Janine (1984) as an influential confrontation with the increasingly toxic military-industrial state of 1980s Britain, the essay interprets Matthew Fitt’s But n Ben A-Go-Go (2000), John Aberdein’s Strip the Willow (2009), and the multiple-author graphic novel IDP: 2043 (2014), edited by Denise Mina, as what Umberto Eco calls “novels of anticipation,” or warnings of the undesirable eventualities that present tendencies may bring about. …”
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Design and Construction of an Electronic Mosquito Repellant. by Kwesiga, Isaac

“…Coils, mats can produce toxic fumes when heated and cause breathing trouble whereas liquid vaporizers can also produce fumes when heated. …”
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Facile Synthesis of Propranolol and Novel Derivatives by Vy Anh Tran, Nguyen Hai Tai Tran, Long Giang Bach, Trinh Duy Nguyen, Thi Thuong Nguyen, Tan Tai Nguyen, Thi Anh Nga Nguyen, The Ky Vo, Thu-Thao Thi Vo, Van Thuan Le

“…Herein, propranolol synthesis proceeded from 1-naphthol and isopropylamine under mild and less toxic conditions. Novel propranolol derivatives were designed by reactions of propranolol with benzoyl chloride, pyridinium chlorochromate, and n-butyl bromide through esterification, oxidation reduction, and alkylation, respectively. …”
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Quantification of Eosinophilic Granule Protein Deposition in Biopsies of Inflammatory Skin Diseases by Automated Image Analysis of Highly Sensitive Immunostaining by Peter Kiehl, Katrin Falkenberg, Markus Vogelbruch, Alexander Kapp

“…Extracellular deposition of toxic eosinophilic granule proteins (EGPs), but not the presence of intact eosinophils, is crucial for their functional effect in situ. …”
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Chemical Constituents, Antioxidant Activities, and Element Concentrations of Rusa Deer Velvet Antler Extracts by Chutima Limmatvapirat, Potcharet Rodhetbhai, Krittaphas Somsakraksanti, Pitcha Danpongprasert, Soranun Poonsub, Wantanwa Krongrawa, Sontaya Limmatvapirat, Maneerat Meepan

“…All extracts were composed of essential elements and had levels of toxic elements and microbial contaminants lower than the acceptable criteria set by ASEAN guidelines. …”
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Analysis of Hazard Area of Dispersion Caused by Leakage from Underground Gas-Storage Caverns in Salt Rock by Ya Yang, Shigang Yang, Zhan Li, Qin Fang, Jianhua Wu, Jiongwei Cai, Wensheng Sun

“…Furthermore, a sample underground gas-storage cavern in salt rock is examined with respect to the toxic threshold limit value and the upper and lower flammability limits. …”
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Anticancer Role of PPARγ Agonists in Hematological Malignancies Found in the Vasculature, Marrow, and Eyes by P. J. Simpson-Haidaris, S. J. Pollock, S. Ramon, N. Guo, C. F. Woeller, S. E. Feldon, R. P. Phipps

“…However, longer survival is accompanied by increased incidence of comorbidities due, in part, to drug side effects and toxicities. It is well accepted that inflammation and tumorigenesis are linked. …”
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A mild and scalable one-pot synthesis of N-substituted 2-aminobenzimidazoles via visible light mediated cyclodesulfurization by Tanawat Rerkrachaneekorn, Rose Malina Annuur, Soraya Pornsuwan, Mongkol Sukwattanasinitt, Sumrit Wacharasindhu

“…The key advantages of this method include the use of less toxic solvent in aqueous media, the elimination of photocatalyst, and a simple, practical setup (one-pot, open-flask, and ambient temperature). …”
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Bisphenol A in Chronic Kidney Disease by Emilio González-Parra, Jose Antonio Herrero, Usama Elewa, Ricardo J. Bosch, Alberto Ortiz Arduán, Jesus Egido

“…BPA is considered an environmental toxicant based on animal and cell culture studies. …”
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Numerical Simulations as Tool to Predict Chemical and Radiological Hazardous Diffusion in Case of Nonconventional Events by J.-F. Ciparisse, A. Malizia, L. A. Poggi, O. Cenciarelli, M. Gelfusa, M. C. Carestia, D. Di Giovanni, S. Mancinelli, L. Palombi, C. Bellecci, P. Gaudio

“…The aim of this paper is to show how CFD calculations can help to understand the time evolution of two possible CBRNe (Chemical-Biological-Radiological-Nuclear-explosive) events: (1) hazardous dust mobilization due to the interaction between a jet of air and a metallic powder in case of a LOVA (Loss Of Vacuum Accidents) that is one of the possible accidents that can occur in experimental nuclear fusion plants; (2) toxic gas release in atmosphere. The scenario analysed in the paper has consequences similar to those expected in case of a release of dangerous substances (chemical or radioactive) in enclosed or open environment during nonconventional events (like accidents or man-made or natural disasters).…”
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