Assessing the Efficacy of Gelatin Composite 3D Scaffolds in Cardiovascular Tissue Engineering: An In Vitro Study by Mohammad Mahdi Safikhani, Azadeh Asefnejad, Rouhollah Mehdinavaz Aghdam, Sadegh Rahmati

“…Biological evaluation demonstrated satisfactory cell adhesion, biocompatibility, and absence of toxicity in the 3D-printed scaffolds. However, altering the printing angle could modify biological properties due to changes in scaffold characteristics. …”
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Gold nanorod-based engineered nanogels for cascade-amplifying photothermo-enzymatic synergistic therapy by Ling Ding, Xiaoshan Wang, Qing Wu, Xia Wang, Qigang Wang

“…Among these, cooperative physical and biochemical activation strategies have attracted increasing attention because of their spatiotemporal controllability, low toxicity, and high therapeutic efficacy. Herein, we demonstrate a nanogel complex as a multilevel ROS-producing system by integrating chloroperoxidase (CPO) into gold nanorod (AuNR)-based nanogels (ANGs) for cascade-amplifying photothermal-enzymatic synergistic tumor therapy. …”
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Changes in wheat protein digestibility and allergenicity: Role of Pediococcus acidilactici XZ31 and yeast during dough fermentation by Wenhui Fu, Chen Chen, Chenglong Liu, Sha Tao, Wentong Xue

“…These results gives valuable insight into the effects of P. acidilactici XZ31 fermentation on the allergenicity and toxicity of wheat proteins, which contribute to promoting the application of multi-strain leavening agent in hypoallergenic and gluten-free wheat products.…”
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Targeted Photodynamic Therapy: A Novel Approach to Abolition of Human Cancer Stem Cells by Anine Crous, Elvin Chizenga, Natasha Hodgkinson, Heidi Abrahamse

“…Photodynamic therapy (PDT) is a clinically approved, minimally invasive, therapeutic procedure that can exert a selective cytotoxic activity toward cancerous cells while reducing toxicity to normal cells. It uses a photosensitizer (PS) that becomes excited when subjected to light at a specific wavelength, and the PS forms reactive oxygen species (ROS) killing malignant cells. …”
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Pharmacophore-based approach for the identification of prospective UDP-2,3-diacylglucosamine hydrolase (LpxH) inhibitor from natural product database against Salmonella Typhi by Divyapriya Karthikeyan, Sanjit Kumar, NS Jayaprakash

“…Both compounds underwent toxicity prediction and ADMET analysis, showing favorable drug-like properties, with compound 1615 emerging as the most promising inhibitor due to its optimal electronic energy and minimal chemical potential. …”
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Advancements in Liposomal Nanomedicines: Innovative Formulations, Therapeutic Applications, and Future Directions in Precision Medicine by Izadiyan Z, Misran M, Kalantari K, Webster TJ, Kia P, Basrowi NA, Rasouli E, Shameli K

“…The recent COVID-19 pandemic has accelerated research in liposomal-based vaccines and antiviral therapies, underscoring the need for improved delivery mechanisms to overcome challenges like rapid clearance and organ toxicity. Furthermore, we discuss the potential of “smart” liposomes, which can respond to specific disease microenvironments, enhancing treatment efficacy and precision. …”
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Chitooligosaccharides suppress airway inflammation, fibrosis, and mucus hypersecretion in a house dust mite-induced allergy model by Yun-Ho Kim, Chan-Ho Park, Ju Myung Kim, Yeo Cho Yoon

“…Chitooligosaccharides (COS) are known for their antioxidant and anti-inflammatory properties.MethodsHuman airway epithelial cells (BEAS-2B) were cultured in DMEM/F12 medium containing COS at concentrations of 25–100 µg/ml for 24 h. No intracellular toxicity was observed up to 1,000 µg/ml. Cell experiments were conducted at COS concentrations below 100 µg/ml, while animal experiments were performed at concentrations below 100 mg/kg body weight for 4 weeks. …”
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Lobar Hepatocellular Carcinoma with Ipsilateral Portal Vein Tumor Thrombosis Treated with Yttrium-90 Glass Microsphere Radioembolization: Preliminary Results by M. Pracht, J. Edeline, L. Lenoir, M. Latournerie, H. Mesbah, O. Audrain, Y. Rolland, B. Clément, J. L. Raoul, E. Garin, E. Boucher

“…Patients were evaluated every 3 to 6 months for response, survival, and toxicity. Mean follow-up was 13.0 months (2.2–50.6). …”
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Evaluation of the Acute Hepatoprotective Potential of Hydroethanolic Extract of Duranta erecta L. Parts by Shadrack Donkor, Christopher Larbie, Gustav Komlaga, Benjamin Obukowho Emikpe

“…The findings suggest that hydroethanolic Duranta erecta ripe fruits extract possesses hepatoprotective and antioxidative activities against CCl4- and acetaminophen-induced toxicity and could be developed as a potent agent for drug-induced liver diseases.…”
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Polyelectrolyte Complexation versus Ionotropic Gelation for Chitosan-Based Hydrogels with Carboxymethylcellulose, Carboxymethyl Starch, and Alginic Acid by Elizabeth Henao, Ezequiel Delgado, Héctor Contreras, Germán Quintana

“…Those materials are commercially available, have low toxicity, and are widely used in the area. These compounds interact through physical crosslinks, which are affected by physical changes of the medium. …”
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Transcriptome response in a marine copepod under multigenerational exposure to ocean warming and Ni at an environmentally realistic concentration by Yunlei Zhang, Shiru Lin, Yaolu Niu, Xiaoping Zhou, Qingxian Lin

“…Overall, this study indicates that both ocean warming and Ni pollution adversely affect the marine copepod T. japonicus from multigenerational transcriptome analysis, especially warming increased Ni toxicity to marine copepods, and our results also provide references to the mechanism concerning the effects of Ni and warming on marine copepods.…”
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Preparation and Optimization of 10-Hydroxycamptothecin Nanocolloidal Particles Using Antisolvent Method Combined with High Pressure Homogenization by Bolin Lian, Yong Li, Xiuhua Zhao, Yuangang Zu, Ying Wang, Yin Zhang, Yuanyuan Li

“…The aim of this study was to prepare 10-hydroxycamptothecin nanocolloidal particles (HCPTNPs) to increase the solubility of drugs, reduce the toxicity, improve the stability of the drug, and so forth. …”
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Evaluation of Toxicological Risks and Effects of Microplastics on Nile Tilapia (Oreochromisniloticus) under in Vitro Laboratory Conditions by Macarius Pancras Mtega, Matobola Joel Mihale, Kessy Fidel Kilulya

“…The objective of research was to determine the toxicity of microplastics to Nile tilapia (Oreochromis niloticus). …”
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Clove oil as a neuromodulator in environmental cadmium cognitive impairment on the prefrontal cortex of Wistar rats by Obinna O. Uchewa, Chinedu B. Egwuagu, Ogugua A. EGWU, Augustine O. Ibegbu

“…Conclusion: Clove oil alleviates cadmium toxicity by increasing antioxidant activity and improving cognition in rats.…”
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Comparative Study of <i>Phytolacca</i> Species Through Morphological, Chloroplast Genome, and Phylogenetic Analysis by Sumin Jeong, Yeseul Kim, Heewon Ji, Jun-Ho Song, Inkyu Park

“…However, because of their potent toxicity, it is essential to distinguish these species. …”
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Metabolomic profiling reveals systemic metabolic disruptions induced by combined exposure to particulate matter and ozone by Yue Ge, Maliha S. Nash, Aimen K. Farraj

“…In conclusion, this study provides new insights into the systemic metabolic effects of air pollutant exposure, identifies novel metabolic targets of pollutant-induced toxicity, highlights the complex interactions resulting from combined exposure to multiple pollutants, and underscores the importance of assessing the combined effects of multiple pollutants in air pollution risk assessments.…”
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Impact of Sars-CoV-2 prophylaxis with tixagevimab-cilgavimab in high-risk patients with B-cell malignancies: a single-center retrospective study. by Giovanni Manfredi Assanto , Matteo Totaro, Poggiali Rebecca, Delli Paoli Adele, Annechini Giorgia, D’Elia Gianna Maria, Aji Francesco, Petrucci Luigi, Fazio Francesca, Del Giudice Ilaria, Martelli Maurizio, Micozzi Alessandra, Giuseppe Gentile

“…In particular, patients affected by lymphoproliferative diseases, given the impaired cell-mediated and antibody-mediated immunity and treatment toxicity, develop more often a symptomatic and a more serious disease of Covid-19. …”
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Local control and recurrence patterns after stereotactic irradiation delivered in more than 4 fractions for hepatocellular carcinomas and liver metastases: a retrospective study by Alizée Renan, Marie Bruand, Maria Jolnerovski, Aboubacar Diallo, Nicolas Demogeot

“…Conclusion Despite dose reductions to spare OAR, SBRT showed satisfactory LC with low toxicity. Out-of-field recurrence remains the most common pattern identified and likely related to underlying disease. …”
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High antimony resistance strain Enterobacter sp. Z1 mediates biomineralization of antimony trioxide by Zijie Zhou, Hongbo Yu, Gejiao Wang, Mingshun Li, Kaixiang Shi

“…The increasing antimony (Sb) contamination prevalence poses a concern owing to its toxicity and potential carcinogenic properties. However, mechanisms underlying the microbial conversion of soluble Sb into insoluble Sb minerals remain unclear. …”
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Innovative approach to Pb (II) removal using zinc-based MOFs-derived carbon: In-depth analysis of adsorption mechanisms, isotherms, thermodynamics, and kinetics by Samira Ahmadzadeh, Alireza Hemmati

“…Water contamination by lead is a critical environmental problem due to its toxicity and persistence in industrial effluents. The removal of lead ions from aqueous solutions has become a significant concern for environmental and public health. …”
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