A Case of Non-Small Cell Lung Cancer with Possible “Disease Flare” on Nivolumab Treatment by Shotaro Chubachi, Hiroyuki Yasuda, Hidehiro Irie, Koichi Fukunaga, Katsuhiko Naoki, Kenzo Soejima, Tomoko Betsuyaku

“…Recent clinical trials proven the clinically significant efficacy and tolerability of nivolumab, a programmed death 1 (PD-1) inhibitor, in previously treated patients with non-small cell lung cancer (NSCLC). …”
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Obesity and Type 2 Diabetes Prevalence in Adults from Two Remote First Nations Communities in Northwestern Ontario, Canada by Pascal Imbeault, François Haman, Jules M. Blais, Shinjini Pal, Tim Seabert, Eva M. Krümmel, Michael A. Robidoux

“…Body weight, height, and waist circumference as well as fasting and postprandial glucose levels following an oral glucose tolerance test were measured in 31 men and 41 women. …”
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Prediction of Pressing Quality for Press-Fit Assembly Based on Press-Fit Curve and Maximum Press-Mounting Force by Bo You, Zhifeng Lou, Yi Luo, Yang Xu, Xiaodong Wang

“…In addition, the maximum press-mounting force calculated by FEA agrees with that obtained by the experimental method, with the maximum deviation being 4.6%, a value that can be tolerated. The comparison shows that the press-fit curve and max press-mounting force calculated by FEA can be used for predicting the pressing quality during precision press-fit assembly.…”
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Spontaneous Nosocomial Pseudomonas aeruginosa Meningitis Presenting as Trismus by C. J. Parr, J. Wheeler, A. Sharma, C. Smith

“…Outpatient follow-up at 46 days revealed normal maximal mouth opening with the ability to chew and tolerate a full diet. Trismus is a motor disturbance of the trigeminal nerve with difficulty in opening the mouth. …”
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Cyclosporine Regimens in Plaque Psoriasis: An Overview with Special Emphasis on Dose, Duration, and Old and New Treatment Approaches by M. D. Colombo, N. Cassano, G. Bellia, G. A. Vena

“…Therefore, the dose should be tailored to patient’s needs and general characteristics and adjusted during the treatment course according to both the efficacy and tolerability. Some studies support the feasibility of pulse administration of CsA for a few days per week for both the induction and the maintenance of response in psoriasis patients. …”
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Female thermal sensitivity and behaviour across the lifespan: A unique journey by Davide Filingeri, Hannah Blount, Alessandro Valenza

“…., changes in breast size) and temperature regulation, heat tolerance, thermal sensitivity and comfort. However, empirical evidence on how skin thermal and wetness sensitivity might change across the lifespan of women, and the implications that this has for female‐specific thermal behaviours, continues to be lacking. …”
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An Immunomodulatory Device Improves Insulin Resistance in Obese Porcine Model of Metabolic Syndrome by Angela J. Westover, Kimberly A. Johnston, Deborah A. Buffington, H. David Humes

“…These changes were associated with improvements in insulin resistance as determined with intravenous glucose tolerance testing. These improvements were also reflected in lowering of homeostatic model assessment- (HOMA-) insulin resistant (IR) scores for up to 2 weeks after SCD therapy. …”
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Transdermal delivery of PeptiCRAd cancer vaccine using microneedle patches by Carmine D'Amico, Manlio Fusciello, Firas Hamdan, Federica D'Alessio, Paolo Bottega, Milda Saklauskaite, Salvatore Russo, Justin Cerioni, Khalil Elbadri, Marianna Kemell, Jouni Hirvonen, Vincenzo Cerullo, Hélder A. Santos

“…Thus, the results of this study demonstrate that the combination of MN technology with PeptiCRAd may provide a safer, more tolerable, and efficient approach to cancer immunotherapy, potentially translatable to other therapeutic applications.…”
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Left Bundle Branch Block Chest Pain Conundrum by Karthik Seetharam, Ayesha Cheema, Gary Friedman, Roman Pachulski

“…The application of more specific, less-sensitive Sgarbossa electrocardiographic criteria may reduce angiographic assessment in an otherwise high-risk population unlikely to tolerate further myocardial injury. We present a case that may facilitate a more nuanced EKG-based approach to distinguish those who may benefit from acute invasive angiography while reducing the frequency of unnecessary angiographic evaluation.…”
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Long term efficacy and safety of Lorlatinib in ALK-positive non-small cell lung cancer: A case report by Jialin Qian, Tianqing Chu

“…During the treatment, the patient tolerated well, no serious adverse events occurred, and the tumor was effectively controlled. …”
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Power Grid Fault Diagnosis Method Using Intuitionistic Fuzzy Petri Nets Based on Time Series Matching by Mingyue Tan, Jiming Li, Xiangqian Chen, Xuezhen Cheng

“…The results for some test cases show that the new method can improve the accuracy and fault tolerance of fault diagnosis, and, furthermore, the abnormal state of the component can be inferred.…”
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Vitamin D on the susceptibility of gestational diabetes mellitus: a mini-review by Ting Zhang, Ting Zhang, Lan Yang, Shuman Yang, Song Gao

“…Gestational diabetes mellitus (GDM), which refers to diabetes mellitus or abnormal glucose tolerance of any degree occurring during pregnancy, is a distinct type within the diabetes classification. 25-hydroxyvitamin D deficiency has been associated with an increased risk of maternal glycaemia, insulin resistance and gestational diabetes. …”
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Galectin-10 Is Released in the Nasal Lavage Fluid of Patients with Aspirin-Sensitive Respiratory Disease by Ma. Cristina Negrete-Garcia, Carla Yoneli Jiménez-Torres, Noe Alvarado-Vásquez, A. Rosalía Montes-Vizuet, J. R. Velázquez-Rodriguez, M. Carmen Jimenez-Martinez, Luis Manuel Teran-Juárez

“…Fifteen ASRD patients, ten aspirin-tolerant asthmatics (ATA), and fifteen healthy controls (HC) were studied. …”
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Influence of Visual Quality and Cultural Background on Consumer Apple Preferences: An Eye-Tracking Study with Chinese and Hungarian Consumers by Xu Cao, Zsuzsanna Horváth-Mezőfi, Zoltán Sasvár, Gergő Szabó, Attila Gere, Géza Hitka, Dalma Radványi

“…The “Threshold of Rejection”, which characterizes consumer tolerance for Apple defects, is introduced in the study. …”
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Addressing the diversity of Xylodon raduloides complex through integrative taxonomy by Javier Fernández-López, M. Teresa Telleria, Margarita Dueñas, Andrew W. Wilson, Mahajabeen Padamsee, Peter K. Buchanan, Gregory M. Mueller, María P. Martín

“…Molecular, morphological, and environmental evidences delimit two lineages within this complex: a Northern Hemisphere clade with longer basidiospores and wider ranges in temperature and precipitation tolerance, and a Southern Hemisphere clade with smaller and more spherical basidiospores, and an isothermal and more humid climate preference. …”
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Selective Extraction and Determination of Chromium Concentration Using Luffa cylindrica Fibers as Sorbent and Detection by FAAS by José A. de Sousa Neto, Jordana de A. N. Oliveira, Lizandra M. C. Siqueira, Vanessa N. Alves

“…Under optimal conditions, the detection and quantification limit for Cr(III) was 19.2 µg·L−1 and 63.9 µg·L−1, respectively, with precision below 0.19%. A high tolerance toward interfering ions was observed for the proposed method. …”
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Daratumumab for Bortezomib-Refractory Proliferative Glomerulonephritis With Monoclonal Immunoglobulin Deposits in Kidney Allograft: A Case Report by Zewei Chen, Shangxi Fu, Jun Wu, Xiaoling Luo, Zhiguo Mao, Dechao Xu, Xiang Gao

“…Daratumumab was shown to successfully reduce proteinuria with stabilizing kidney function and was well-tolerated in this patient, which supports that daratumumab appears to be a viable option for treatment-resistant PGNMID.…”
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Genetic divergence studies in little millet (Panicum sumatrense Roth. ex. Roem. & Schult) using D2 statistics and molecular markers by Kinal Patel, Arna Das*, Dhrumi Dalsaniya, Hadassah Mamidipalli, Sanjith Vasala and Harshal E. Patil2

“…Little millet is well known for abiotic stress tolerance and high nutritional value. Focused research can bring this crop into mainstream cultivation with good economic return. …”
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Intermittent Fasting Modulation of the Diabetic Syndrome in Streptozotocin-Injected Rats by Louiza Belkacemi, Ghalem Selselet-Attou, Emeline Hupkens, Evrard Nguidjoe, Karim Louchami, Abdullah Sener, Willy J. Malaisse

“…Intermittent fasting improved glucose tolerance, increased plasma insulin, and lowered Homeostatis Model Assessment index. …”
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Intensity-Modulated Radiotherapy for a Rendu-Osler-Weber Disease Patient with Recurrent Severe Epistaxis: A Case Report by Maximilian Niyazi, Marco-Domenico Caversaccio, Patrick Dubach, Andreas Geretschläger, Andreas Arnold, Claus Belka, Daniel M. Aebersold, Norbert M. Blumstein

“…The therapy was very well tolerated, no acute toxicities occurred. Two weeks after the last radiation dose had been applied, the nasal dressing could be removed without problems. …”
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