Olanzapine for young PEople with aNorexia nervosa (OPEN): results of a feasibility study by Olena Said, Dominic Stringer, Ece Sengun Filiz, Hiba Mutwalli, Sevgi Bektas, Melahat Nur Akkese, Vanessa Kellermann, Katie Ireland, Elizabeth Tyrrell-Bunge, Demelza Beishon-Murley, Joel W. T. Khor, Lee Allman, Joanna Barker, Nicus Kotze, Ben Carter, Mima Simic, Dilveer Singh Sually, Jessica Bentley, Allan H. Young, Sloane Madden, Sarah Byford, Sabine Landau, Vanessa Lawrence, Janet Treasure, Ulrike Schmidt, Dasha Nicholls, Hubertus Himmerich

“…Its effect on eating disorder (ED) psychopathology, its efficacy and tolerability, and its acceptability and adherence rate are unclear. …”
Get full text

Genome-wide association mapping and genomic prediction analyses reveal the genetic architecture of grain yield and agronomic traits under drought and optimum conditions in maize by Manigben Kulai Amadu, Yoseph Beyene, Vijay Chaikam, Pangirayi B. Tongoona, Eric Y. Danquah, Beatrice E. Ifie, Juan Burgueno, Boddupalli M. Prasanna, Manje Gowda

“…Abstract Background Drought is a major abiotic stress in sub-Saharan Africa, impacting maize growth and development leading to severe yield loss. Drought tolerance is a complex trait regulated by multiple genes, making direct grain yield selection ineffective. …”
Get full text

Interactions of the emerging fungus Candida auris with Acanthamoeba castellanii reveal phenotypic changes with direct implications on the response to stress and virulence by Michele Ramos Valente, Lucas Martins Alcântara, Deborah Santos Cintra, Susana Ruiz Mendoza, Elisa Gonçalves Medeiros, Kamilla Xavier Gomes, Leandro Honorato, Marcos de Abreu Almeida, Carmen Baur Vieira, Joshua Daniel Nosanchuk, Diana Bridon da Graça Sgarbi, Marcia Ribeiro Pinto, Leonardo Nimrichter, Allan Jefferson Guimarães

“…However, both isolates were more tolerant to itraconazole and caspofungin, particularly MMC2, which showed differential expression of ergosterol biosynthesis enzymes and increased cell wall polysaccharides. …”
Get full text

Single Dose of Attenuated Vaccinia Viruses Expressing H5 Hemagglutinin Affords Rapid and Long-Term Protection Against Lethal Infection with Highly Pathogenic Avian Influenza A H5N1... by Fumihiko Yasui, Keisuke Munekata, Tomoko Fujiyuki, Takeshi Kuraishi, Kenzaburo Yamaji, Tomoko Honda, Sumiko Gomi, Misako Yoneda, Takahiro Sanada, Koji Ishii, Yoshihiro Sakoda, Hiroshi Kida, Shosaku Hattori, Chieko Kai, Michinori Kohara

“…Although these vaccines are well tolerated, their immunogenicity and cross-reactivity with viruses of different clades can be improved. …”
Get full text

Surgical options for Evans-Jensen type IV intertrochanteric femur fractures in the elderly over 65: a comparison between total hip arthroplasty and proximal femoral nail antirotati... by Ming Sun, Hai-Rui Liang, He Zhang, Tong Bai, Rong-Da Xu, Si-Yu Duan, Zhen-Cun Cai, Zhen-Cun Cai

“…There was no significant difference in the overall incidence of postoperative complications between the two groups (p = 0.41).ConclusionFor elderly patients over 65 years old with Evans-Jensen Type IV intertrochanteric femur fractures, especially those with underlying diseases who cannot tolerate prolonged bed rest, hip replacement surgery (THA) may be preferred. …”
Get full text

The Application of Magnetic-Controlled Capsule Gastroscopy in Patients Refusing C-EGD: A Single-Center 5-Year Observational Study by Lihan Zhou, Sijia Wang, Jian Li, Jie Zhong, Ling Zhang, Ruizhe Shen, Bielike Kouken, Chunhua Zhou, Qi Wang, Yuting Qian, Duowu Zou, Ye Chu

“…Conclusion. MCCG is well tolerated, safe, and technically feasible and has a considerable diagnostic yield. …”
Get full text

Population Dynamics of the Crocodile Shark, <i>Pseudocarcharias kamoharai</i>, in the Tropical Equatorial Pacific Ocean, Ecuador by Marcos Douglas Calle-Morán, Eugenio Alberto Aragón-Noriega, Ana Rosa Hernández-Téllez, Emigdio Marín-Enríquez, Javier Tovar-Ávila, Juan Francisco Arzola-González, Jorge Payán-Alejo

“…These values and their life history traits indicated that this shark species cannot tolerate any fishing level without threatening its populations.…”
Get full text

Pharmacokinetic Analysis of an Isoniazid Suspension Among Spanish Children Under 6 Years of Age by Antoni Noguera-Julian, Emma Wilhelmi, Maria Cussó, Rob Aarnoutse, Angela Colbers, Loreto Martorell, Maria Goretti López-Ramos, Joan Vinent, Rosa Farré, Dolors Soy, Sílvia Simó-Nebot, Clàudia Fortuny

“…Significant differences in C_max (<i>p</i> = 0.030) and AUC_0–24h (<i>p</i> = 0.011) values were observed based on acetylator status. Treatment was well tolerated, and no severe adverse events were observed; three patients developed asymptomatic mildly elevated alanine aminotransferase levels. …”
Get full text

Effect of Midsole Compliance on Oxygen Consumption and Perception of Effort and Comfort during running by Kai Biedermann, Gian-Andri Baumann, Christina M. Spengler, Fernando G. Beltrami

“… Introduction Advanced Footwear Technology (AFT) enhances running economy, which is partly attributed to midsole foam properties such as high resilience (the ability of a material to absorb and recover energy under elastic deformation) and high compliance (the tolerance of a material to deformation). While compliant midsoles are known to improve running economy over non-compliant ones, the impact of further increasing compliance in already compliant midsoles remains unclear. …”
Get full text

Soviet Researchers on the Middle East: Ahead of Their Time by I. D. Zvyagelskaya

“…The theory of socialist orientation was based on original ideas of Marxism founders and further developed by Lenin who insisted that economically underdeveloped countries can with the help of the proletariat from advanced countries go directly to socialism bypassing capitalism.The reality of revolutions without the proletariat and the desire to take advantage of the anti-colonial struggle to establish full-scale presence of the USSR in the Middle Eats made the Soviet leadership more tolerant of scientists' attempts to realistically analyze regional trends and developments.For instance, in the Soviet era, politicians were tempted to explain all conflicts in the regions of the Third world, and particularly in the Middle East exclusively by the workings of imperialism. …”
Get full text

The biomechanical effects of treating double-segment lumbar degenerative diseases with unilateral fixation through interlaminar fenestration interbody fusion surgery: a three-dimen... by Kai-Kai Feng, Xiao-Bing Xiang, Cheng-Peng Li, Kai-Yin Gao, Wei-Wei Zhang, Zhen-Yu Nie, Wen-Xin Liao, Dong Zhao, Guang-Ru Cao

“…This provides some biomechanical evidence for selecting surgical approaches for elderly patients who cannot tolerate long surgeries, suggesting that two-segment unilateral fixation may be advisable. …”
Get full text

Control of Ectoparasitic Monogenean Infestation on GIFT Tilapia (Oreochromis sp.) using Salt Addition by Yani Hadiroseyani, L.S. Harti, Sri Nuryati

“…The objectives of this study were to examine monogenean parasites species in GIFT (Genetically Improved Farmed Tilapia) tilapia, their tolerance to salt concentration and the most effective salt concentration to control the parasites. …”
Get full text

Realization of a cascade treatment algorithm for glaucoma in St. Petersburg by A.V. Antonova, V.P. Nikolaenko, V.V. Brzheskiy

“…Preservative-free prostaglandin analogues improve treatment tolerability, adherence to treatment, and chances for success of IOP-lowering surgery. …”
Get full text

Le mouvement étudiant et la question des langues en Algérie (1962-1965) : à propos d’un épisode méconnu de l’histoire de l’UGEMA-UNEA by Yassine Temlali

“…In return, its organic autonomy was generally tolerated by the FLN, and it received subsidies and logistical support.The burial of proposals in favour of Berber languages at the Fifth Congress of the UGEMA would also carry the mark of the alliance of the communists with Ahmed Ben Bella. …”
Get full text

Socio-economic assessment of drought impacts in Lesotho: implications for early action by Relebohile Agnes Mojaki, Makoala Vitalis Marake, Evan Easton-Calabria, Joalane Rethabile Marunye, Erin Coughlan de Perez

“…Informants also perceived the following actions could be taken before a drought is manifested: clear agro-climatological early warning messages, tailor-made drought-relevant advisories, water harvesting and availability of drought-tolerant seeds. It is thus imperative to streamline policy interventions regarding dissemination of early warning messages and anticipatory actions to reduce the negative impacts of drought on livelihoods. …”
Get full text

Inventarisation of Parasite in ”Dumbo” Catfish Clarias sp. from Bogor Region by Y. Hadiroseyani, P. Hariyadi, Sri Nuryati

“…Few quantities of parasite infection may still be tolerated by the host, however high intensity of infection can impair to fish metabolism or even damage of organelle.  …”
Get full text

Les macaques de Tonkéan (Macaca tonkeana) et les macaques rhésus (Macaca mulatta) discriminent-ils les mêmes indices sociaux d’un partenaire humain ? by Charlotte Canteloup, Dalila Bovet, Helene Meunier

“…Nous avons testé deux espèces de macaques socialement divergentes, les macaques de Tonkéan, (Macaca tonkeana), tolérants et égalitaires, et les macaques rhésus, (Macaca mulatta), caractérisés par une hiérarchie de dominance plus stricte, afin d’investiguer l’influence du type de sociabilité sur ces performances cognitives. …”
Get full text

Dynamic Digital Radiography (DDR) in the Diagnosis of a Diaphragm Dysfunction by Elisa Calabrò, Tiana Lisnic, Maurizio Cè, Laura Macrì, Francesca Lucrezia Rabaiotti, Michaela Cellina

“…A 46-year-old male, a former smoker, was evaluated for unexplained dyspnea and reduced exercise tolerance. His medical history included a SARS-CoV-2 infection in 2021. …”
Get full text

Genome-Wide Comprehensive Identification and In Silico Characterization of Lectin Receptor-Like Kinase Gene Family in Barley (Hordeum vulgare L.) by Fee Faysal Ahmed, Farah Sumaiya Dola, Md Shohel Ul Islam, Fatema Tuz Zohra, Nasrin Akter, Shaikh Mizanur Rahman, Md. Abdur Rauf Sarkar

“…They play crucial roles in plant growth, development, immune responses, signal transduction, and stress tolerance. However, the genome-wide identification and characterization of LecRLK genes and their regulatory elements have not been explored in a major cereal crop, barley (Hordeum vulgare L.). …”
Get full text

Exploraciones personales sobre las condiciones precedentes de la violencia sexual en el marco del conflicto armado enColombia by Paula Natalia Rincón Chitiva, Juan Felipe Monroy Simbaqueba

“…It became evident that in the armed conflict, sexual violence is possible because it is based on gender inequalities already present in the relationships and the communities, which result in a high social tolerance for it. Additionally, sexual violence is supported by masculinities and femininities that have normalized power relationships in which men dominate and demonstrate their violent actions, and women are taken as available bodies with limited abilities, whose ways of being respond to impositions of a patriarchal culture. …”
Get full text