Potential Antioxidant Activity of New Tetracyclic and Pentacyclic Nonlinear Phenothiazine Derivatives by Godwill Azeh Engwa, Eugene Lekem Ayuk, Benardeth Ujunwa Igbojekwe, Marcellus Unaegbu

“…Further study is needed to identify tolerable doses for possible therapeutic purposes.…”
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A deep dive into cation-modified structural, mechanical, magneto‑electronic, and thermophysical properties of MAlO3 (M = Ca, Sr, Ba, and Ra): First-principles investigation by Asif Hosen, Md. Rafiqul Islam, Ahmad A. Mousa, Mohammed S. Abu-Jafar

“…The structural stability of the perovskite candidates under investigation is confirmed by the combined assessment of the tolerance factor and enthalpy of formation energy. …”
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Issues of diagnostics and treatment of abdominal pain at irritable bowel syndrome at outpatient stage of the healthcare by Yu. A. Kucheryavy, T. L. Lapina, M. A. Livzan, M. F. Osipenko

“…The rate of adverse events and tolerability of hyoscine butylbromide are comparable to that of placebo.Conclusion. …”
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Clinical Benefits of Metronomic Chemotherapy in Platinum-Refractory, Recurrent, and Metastatic Head and Neck Squamous Cell Carcinoma by Amira Elwan, Adel Bakry, Mohamed Eesa, Hoda Ismail, Mohamed Alnemr

“…Two median years PFS was 4 months, and two median years OS was 8 months (SPSS 16.0 for Windows, Wilcoxon signed-rank test, P value ≤ 0.05 is significant).Conclusion: Capecitabine, methotrexate, and celecoxib combined chemotherapy are effective and tolerable in treating platinum-refractory, recurrent, and metastatic HNSCC with non-inferior clinical outcome results, especially in poor societies.…”
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Modelling relative richness of flooding-response groups to predict hydrology-driven change in wetland plant communities by David C. Deane, Michelle T. Casanova, Jason Nicol, Justin D. Brookes

“…Grouping plant species by flooding tolerance simplifies hydrological response modelling, with changes in group representation along the hydrological gradient defining both distinct vegetation zones and transition thresholds between them. …”
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Evaluation of Mangrove Water Quality in Pancer Cengkrong, Trenggalek and Sine, Tulungagung, East Java, Indonesia Using Phytoplankton as Bioindicators by Satria Cahya Febriansyah, Luchman Hakim, Catur Retnaningdyah

“…Phytoplankton data was used to measure, trophic diatom index (TDI) as an indicator of water nutrition status, and pollution tolerant value (%PTV) as an indicator of organic pollution. …”
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Diagnosis of Gestational Diabetes Mellitus with Point-of-Care Methods for Glucose versus Hospital Laboratory Method Using Isotope Dilution Gas Chromatography-Mass Spectrometry as R... by Karl Kristensen, Anne-Marie Wangel, Anastasia Katsarou, Nael Shaat, David Simmons, Helena Fadl, Kerstin Berntorp

“…A 75 g oral glucose tolerance test was performed on 135 women screened positive for GDM. …”
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Bacteria-Inspired Synthesis of Silver-Doped Zinc Oxide Nanocomposites: A Novel Synergistic Approach in Controlling Biofilm and Quorum-Sensing-Regulated Virulence Factors in <i>Pseu... by Abirami Karthikeyan, Manoj Kumar Thirugnanasambantham, Fazlurrahman Khan, Arun Kumar Mani

“…In this study, metal-tolerant bacteria were isolated from a metal-contaminated site and screened for their ability to synthesize multifunctional nanocomposites (NCs). …”
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Assessing the Short-Term Efficacy and Safety of Guselkumab for Moderate-to-Severe Plaque Psoriasis: Meta-Analysis of Randomized Controlled Trials by Jing Yang, Zongming Wang, Xilin Zhang

“…The guselkumab was more effective and had the similar tolerance. Conclusion. The guselkumab had excellent efficacy and great safety in moderate-to-severe plaque psoriasis, but long-term safety remained to be determined.…”
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Characterization of <i>PHT</i> Genes in ‘duli’ (<i>Pyrus betulifolia Bunge</i>) and Expression Analysis of <i>PbPHTs</i> in Response to Plant Growth Regulators, P, and Salt Stress... by Shuai Yuan, Weilong Zhang, Yuxing Zhang

“…This study therefore provides a list of <i>PbPHT</i> genes with substantial roles in abiotic stress response, as well as important information to understand the functional characteristics of <i>PbPHT</i> during ‘duli’ abiotic stress tolerance, and explores the function of PbPHTs in exogenous hormones, phosphorus, and salt stress in the future.…”
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Preliminary study on mercury pollution affecting soil bacteria near a mercury mining area by Jianxiong Du, Yili Yuan, Jianfeng Li, Shuqing Zhang, Yuxiang Ren

“…The results of this study provide a scientific reference and impetus for further research on the mechanism(s) responsible for tolerance to high mercury stress in mercury-contaminated soil.…”
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<i>Phytophthora</i> Species and Their Associations with Chaparral and Oak Woodland Vegetation in Southern California by Sebastian N. Fajardo, Tyler B. Bourret, Susan J. Frankel, David M. Rizzo

“…Additionally, California’s natural areas, characterized by a Mediterranean climate and dominated by chaparral (evergreen, drought-tolerant shrubs) and oak woodlands, lack sufficient baseline knowledge on <i>Phytophthora</i> biology and ecology, hindering effective management efforts. …”
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A Unique Case of Mantle Cell Lymphoma Masquerading as a Cecal Mass by Sarahi Herrera-Gonzalez, Dema Shamoon, Tingliang Shen, Simon Badin, Yatinder Bains

“…Treatment involves conventional chemo-immunotherapy consisting of R CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) or RB (rituximab and bendamustine), with the latter being better tolerated and associated with longer progression-free survival. …”
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Rebuilding Soil Ecosystems for Improved Productivity in Biosolarized Soils by Laura Ney, Dorcas Franklin, Kishan Mahmud, Miguel Cabrera, Dennis Hancock, Mussie Habteselassie, Quint Newcomer, Brendan Fatzinger

“…Soils that received the highest rate of compost immobilized the greatest proportion of nitrogen applied, were the most cold-tolerant, and produced the largest yields. None of the kale that received heavy mineral fertilization without LEM inoculation survived a hard freeze; however, the ones that received LEM applications were able to partially recover. …”
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Pimavanserin Treatment for Parkinson’s Disease Psychosis in Clinical Practice by Khashayar Dashtipour, Fiona Gupta, Robert A. Hauser, Cherian A. Karunapuzha, John C. Morgan

“…Issues addressed include distinguishing PDP from similar symptoms caused by other disorders such as dementia, coordinating pimavanserin with other PD medications and with deep brain stimulation, adapting pimavanserin dosing for optimal benefit and tolerability, and recognizing variability of PDP symptoms due to patients’ changing life circumstances. …”
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Prioritization of Erosion Hotspot Microwatersheds for Conservation Planning Using GIS and Remote Sensing Techniques in Antsokia-Gemiza District of North Shewa Zone, Ethiopia by Estifanos Lemma, Yitea Seneshaw Getahun, Tadesse Getachew

“…About 12442.86 ha (33.18%) of the district falls under low and moderate severity classes, and it has a total soil loss not exceeding 11 t·ha−1year−1 (which is an acceptable or tolerable range of soil loss). The rest of the land, which covers 25046.32 ha (66.82%) of the area, falls under high to extremely severe classes (which need prime attention), with soil loss amounts ranging from 11.01 to 240 t·ha−1year−1. …”
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Efficacy of 2 L versus 3 L polyethylene glycol in bowel preparation: a real-world study by LI Jiaojun, LI Jiaojun, TAN Xianhao, TAN Xianhao, ZHANG Chen

“…Secondary outcome indicators included the BBPS score, polyp detection rate (PDR), tolerability, compliance, and incidence of adverse events. …”
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Comparison of Conservation Strategies for California Channel Island Oak (Quercus tomentella) Using Climate Suitability Predicted From Genomic Data by Alayna Mead, Sorel Fitz‐Gibbon, John Knapp, Victoria L. Sork

“…Previous work has shown that Island Oaks on each island are genetically differentiated, but it is unclear whether assisted gene flow could enable populations to tolerate future climates. We performed whole‐genome sequencing on Island Oak individuals and Q. chrysolepis, a closely related species that hybridizes with Island Oak (127 total), to characterize genetic structure and introgression across its range and assess the relationship between genomic variation and climate. …”
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Insulin autoimmune syndrome in a 3-year-old boy: the youngest to date in China and a narrow review by Ming Cheng, Yuan Ding, Dongmei Wang, Chunxiu Gong

“…During an extended oral glucose tolerance test (OGTT), his insulin to C-peptide molar ratio was greater than 1, and anti-insulin antibodies (IAAs) measurements were as high as 54.38 COI (normal range 0–1 COI). …”
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Real-world safety of linaclotide in Chinese patients with irritable bowel syndrome with constipation: a multicenter, single-arm, prospective observational study by Yinglian Xiao, Xianmei Meng, Qingfeng Luo, Xiaohua Hou, Jie Jin, Xianfei Zhong, Wei Gong, Xiuling Li, Minhu Chen

“…Conclusion: In the Chinese real-world setting, linaclotide was safe and well tolerated in patients with IBS-C. Numerically, there are trends toward improvement in PROs with linaclotide treatment.…”
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