Medical cannabis in the management of musculoskeletal pain: a systematic review of clinical trials by Przemysław Płatek, Laura Piejko

“…Overall, medical cannabis was generally well tolerated and was associated with significant pain reduction, improved motor function, enhanced sleep quality, and overall improvements in health-related quality of life. …”
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Extraction of Oil from Azadirachta indica and Moringa stenopetala Seeds and Evaluation of its Physicochemical Properties by Degnechew Genene

“…Azadirachta indica and Moringa stenopetala trees have been regarded as underutilized, tropical plants, fast-growing, drought-tolerant, robust, oleaginous, and evergreen perennial trees growing widely in various regions of Ethiopia. …”
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Efficacy of the Fumigant Ethanedinitrile to Control the Ham Mite, <i>Tyrophagus putrescentiae</i> (Schrank) (Sarcoptiformes: Acaridae), and Its Sorption on Dry-Cured Ham by Jacqueline M. Maille, Wes Schilling, Thomas W. Phillips

“…The results showed that eggs were the most tolerant life stage to EDN fumigation, with an estimated LC₅₀ of 0.6 mg/L. …”
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Study of the Feasibility of Regeneration of Central Worn-Out Textures of Ilam City Based on Urban Smart Growth Approach by pakzad azadkhani, mohammad Salavarzizadeh, Fatemeh Farogh Doost

“…One of the safest and most practical solutions for urban planners is to assess the feasibility of regenerating such textures to determine the levels that can be regenerated and are relatively good and tolerable for urban society. Therefore, the present study aims to investigate the feasibility of regenerating worn-out textures of Ilam City based on urban smart growth approach using a descriptive-analytical methodology. …”
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Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis: A Randomized Controlled Trial by Mir Sadat-Ali, Abdallah S. AlOmran, Sulaiman A. AlMousa, Hasan N. AlSayed, Khalid W. AlTabash, Mohammed Q. Azam, Tarek M. Hegazi, Sadananda Acharya

“…Patients were followed up for 3, 12, and 24 months to assess efficacy, safety, and tolerability. To assess the cartilage regeneration of the damaged cartilage, magnetic resonance imaging (MRI) was used. …”
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Psychological and legal aspects of cyberbullying by O. L. Matsiuk, I. V. Maslyanikova

“…The article states that parents, teachers/educators should be an example of tolerant behavior, organize various activities to bring them closer to students, be sure to work with a psychologist, involve children in various clubs/sections, creative work, where respect and goodwill will be promoted. …”
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Water‐Triggered Reconfigurable Glycerogels for Sustainable All‐Gel Supercapacitors by Md. Tariful Islam Mredha, Adith Varma Rama Varma, Tanish Gupta, Insu Jeon

“…Furthermore, it can tolerate extreme mechanical deformations (e.g., stretching, bending, and twisting) and temperatures (−20 to 80 °C). …”
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Lifting Techniques: Why Are We Not Using Evidence To Optimize Movement? by Nicholas B. Washmuth, Abby D. McAfee, C. Scott Bickel

“…When applying this clinical framework, clinicians should consider metabolic, biomechanical, physical stress tolerance, and pain factors in order to address the movement system. …”
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‘I really feel like I am ageing early’: an interpretative phenomenological analysis of the lived experience of young adults with life-limiting conditions (YALLC) by Poh Heng Chong, Xiangyi Chen, Zhi Zheng Yeo, Celene Ting, Ya Nee Poh, Qishun Raymond Ang

“…In-depth, semistructured interviews were conducted, and verbatim transcripts analysed iteratively.Results Four major themes emerged: (1) living with limitations and in limbo—compressed timelines and confusion, triggered by dissonance between age-expected versus developmentally appropriate aspirations and goals; (2) experiencing identity crises, confronting existential concerns and chasing the elusive goal of enduring connection—struggle between public versus self-identities, including issues around self-worth and purpose; (3) striving for autonomy while tolerating interdependence/codependence—tensions arising from their desire for independence against the need to rely on others and (4) accepting and appreciating LLC as integral to one’s existence—demonstrating adaptability, creativity and resilience. …”
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Combination Ciprofloxacin and Metronidazole for Active Crohn’s Disease by Susan L Greenbloom, A Hillary Steinhart, Gordon R Greenberg

“…Ciprofloxacin in combination with metronidazole is well tolerated and appears to play a beneficial role in achieving clinical remission for patients with active Crohn's disease, particularly when there is involvement of the colon.…”
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Effect of biogenic polyamines on sliding motility of mycobacteria in the presence of antibiotics by I. V. Tsyganov, A. G. Tkachenko

“…Furthermore, animal tissues contain biogenic polyamines, which can increase tolerance of microorganisms to stresses, including antibiotics, and modulate cell motility. …”
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Risk Factors Analysis of Cutaneous Adverse Drug Reactions Caused by Targeted Therapy and Immunotherapy Drugs for Oncology and Establishment of a Prediction Model by Zimin Zhang, Mingyang Zhu, Weiwei Jiang

“…ABSTRACT Targeted therapy and immunotherapy drugs for oncology have greater efficacy and tolerability than cytotoxic chemotherapeutic drugs. However, the cutaneous adverse drug reactions associated with these newer therapies are more common and remain poorly predicted. …”
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Growth Characteristics of Sheep-Derived <i>Bacteroides fragilis</i> and Preliminary Research on Effects in Mice and Lambs by Cheng Cheng, Jinye Du, Jianping Tao, Darong Cheng

“…The experiments demonstrated that the <i>Bacteroides fragilis</i> isolate grows well under mildly acidic conditions (pH 6–8), exhibits some tolerance to bile salts, and has survival rates of 38.89% and 92.22% in simulated gastric and intestinal fluids, respectively, indicating its potential as a probiotic. …”
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FBXL16 Promotes Endometrial Progesterone Resistance via PP2AB55α/Cyclin D1 Axis in Ishikawa by Haoen Liu, Li Han, Liyan Zhong, Xiaodan Zhuang, Yan Peng

“…The high expression of FBXL16 was positively correlated with MPA resistance and poor prognosis of endometrial cancer. MPA tolerance of endometrial cancer cells was inhibited by knockdown of FBXL16 in DNA content assessment, CCK-8, and colony formation. …”
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A Case of Visceral Leishmaniasis in a 4-Year-Old Child Living in Nonendemic Area Located in Suburbs of Dakar, Senegal by Magatte Ndiaye, Dienaba Fafa Cissé, Aicha Djigal, Aminata Sow, Souléye Lélo, Fatoumata Ly, Isaac A. Manga, Mame Ami Diouf, Doudou Sow, Oumar Gaye, Boubacar Camara, Babacar Faye

“…At admission, the patient presented with epistaxis and gingivorrhagia, a severe anaemic syndrome poorly tolerated, a systemic inflammatory response syndrome with fever at 39.5°C, a tumoral syndrome with 11 cm of hepatomegaly and 12 cm of type IV splenomegaly, and noninflammatory macropoly adenopathies. …”
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Odevixibat treatment in a child with hypoplastic left heart syndrome and severe cholestatic pruritus: a case report by Rainer Ganschow, Christof Maucksch, Peter Rauschkolb, Martin B. E. Schneider

“…In this case report, odevixibat was effective and well tolerated. Together with those of previous studies in patients with progressive familial intrahepatic cholestasis and Alagille syndrome, these results suggest that odevixibat warrants further study as a potential treatment option for patients with cholestatic pruritus of diverse etiologies.…”
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Gene expression signatures between Limia perugiae (Poeciliidae) populations from freshwater and hypersaline habitats, with comparisons to other teleosts. by Elizabeth J Wilson, Nick Barts, John L Coffin, James B Johnson, Carlos M Rodríguez Peña, Joanna L Kelley, Michael Tobler, Ryan Greenway

“…Our analyses of gill gene expression revealed potential molecular mechanisms underlying salinity tolerance in this species, including the enrichment of genes involved in ion transport, maintenance of chemical homeostasis, and cell signaling in the hypersaline population. …”
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Evaluation of Soil Drainage Methods for the Productivity of Waterlogged Vertisols in Jama District, Eastern Amhara Region, Ethiopia by Muluken Lebay, Wudu Abiye, Tilahun Taye, Seid Belay

“…Drainage method BBF120 gave 34.6% and 17.3% of grain yield advantage over the drainage methods of BBF40 and BBF80, respectively, whereas soil loss was not significantly (P>0.05) different among all treatments; it is still in the range of soil loss tolerance in Ethiopia. As enhanced drainage is a requirement for successful crop production on Vertisol areas, BBF120 is recommended for draining excess runoff and consequently maximizing the yield of wheat in the study area and others with a similar farming system and agroecology.…”
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Corynebacteria from the respiratory microbiota modulate inflammatory responses and associate with a reduced pneumococcal burden in the lungs by Caroline Bergenfelz, Phuong Do, Liv Larsson, Hanna Ivarsson, Kasper Malmborn, Anders P. Håkansson

“…The inflammatory response and the bacterial burden of both species over time were determined by Western blot, luciferase assay, cytokine bead array, flow cytometry and viable plate counts on blood agar plates.ResultsClinical isolates of Corynebacteria were well tolerated by human cells and mice. Corynebacteria induced a transient inflammatory response during healthy conditions in the absence of known pathogens. …”
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Autophagy: A New Avenue and Biochemical Mechanisms to Mitigate the Climate Change by Muhammad Abubakkar Azmat, Malaika Zaheer, Muhammad Shaban, Saman Arshad, Muhammad Hasan, Alyan Ashraf, Muhammad Naeem, Aftab Ahmad, Nayla Munawar

“…Autophagy in plants offers a viable way to increase plant resilience to climate change by increasing stress tolerance and nutrient usage efficiency.…”
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