Manganese Neurotoxicity as a Complication of Chronic Total Parenteral Nutrition by Alisha Khan, Jonathan Hingre, Amit S. Dhamoon

“…Total parenteral nutrition (TPN) is an increasingly used potentially lifesaving therapy for patients who cannot tolerate enteral nutrition. However, when used over a period of several weeks to months, its associated risks and complications carry significant morbidity and mortality. …”
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A Wearable Iron-Based Implant as an Intramedullary Nail in Tibial Shaft Fracture of Sheep by Sitaria F. Siallagan, Marzuki Silalahi, Arief Boediono, Sri Estuningsih, Deni Noviana

“…Therefore, it could be concluded that the iron-based implant is tolerable for a period of 9 months. It also has the potential to be used as a biodegradable orthopedic implant.…”
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B-CD8+ T Cell Interactions in the Anti-Idiotypic Response against a Self-Antibody by Darel Martínez, Amaury Pupo, Lianet Cabrera, Judith Raymond, Nichol E. Holodick, Ana María Hernández

“…Both humoral and CTL anti-idiotypic responses could be mechanisms to protect against the self-reactive antibody, contributing to keeping the tolerance to self-antigens.…”
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Effect of VPAC1 Blockade on Adipose Tissue Formation and Composition in Mouse Models of Nutritionally Induced Obesity by H. Roger Lijnen, Kathleen Freson, Marc F. Hoylaerts

“…In addition, MAb 23A11 had no significant effect on glucose tolerance or insulin resistance in lean or obese C57Bl/6 mice. …”
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A Cost-effective Breath-hold Coaching Camera System for Patients Undergoing External Beam Radiotherapy by Akash Mehta, Emma Horgan, Prabhakar Ramachandran, Christopher Noble

“…All volunteers successfully followed instructions and maintained BH within ± 1 mm tolerance. Conclusions: This study demonstrates the feasibility of using a cost-effective ToF camera to coach patients before imaging/treatment, saving valuable LINAC linac and imaging system time.…”
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Bond Strength and Deflection of Four Types of Bonded Lingual Retainers by Amin Golshah, Shirin Asadian Feyli

“…The three-strand and Retanium wires can probably better tolerate intraoral forces and have higher resistance to fracture due to having higher TBS. …”
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Rapid life-history evolution reinforces competitive asymmetry between invasive and resident species by Chapuis, Elodie, Jarne, Philippe, David, Patrice

“…In addition, our experiments suggest that A. marmorata populations having experienced competition by P. acuta for sufficient time in nature, have evolved to become even less tolerant to it. Though apparently paradoxical, this result supports the hypothesis that rapid life-history evolution has allowed A. marmorata not to resist competition, but to avoid it by increasing its specialization into the colonizer lifestyle previously documented by long-term field surveys. …”
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Purification and expression of a novel bacteriocin, JUQZ-1, against Pseudomonas syringae pv. Actinidiae (PSA), secreted by Brevibacillus laterosporus Wq-1, isolated from the rhizos... by Yang Shuai, Yi Langbo, Yang Yi, Chen Danni, Peng Qingzhong

“…., JUQZ-1, a protein with antimicrobial properties and strong environmental tolerance, may serve as a promising alternative to antibiotics.…”
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Retrospective Analysis of Healthcare Resource Use, Treatment Patterns, and Treatment-related Events in Patients with Huntington’s Disease–associated Chorea Initiated on Tetrabenazi... by Victor W. Sung, Sanjay K. Gandhi, Victor Abler, Brian Davis, Debra E. Irwin, Karen E. Anderson, Ravi G. Iyer

“…Tetrabenazine was the first approved treatment for chorea, although tolerability concerns exist. **Objectives:** To characterize demographic and clinical characteristics of HD patients with chorea based on tetrabenazine use and examine treatment persistence with tetrabenazine in a real-world setting. …”
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Mobilization of plant genetic resources from the territory of Astrakhan Province, Russia by M. O. Burlyaeva, G. A. Gridnev, E. V. Miroshnichenko

“…Many of the collected plant forms and populations with valuable biological traits deserve to be included in introduction trials and breeding programs, especially those that may serve as sources of heat, drought and salt tolerance.…”
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Defect modeling in semiconductors: the role of first principles simulations and machine learning by Md Habibur Rahman, Arun Mannodi-Kanakkithodi

“…Overall, the advent of ‘DFT+ML’ promises to drive advancements in semiconductor technology, catalysis, and renewable energy applications, paving the way for the development of high-performance semiconductors which are defect-tolerant or have desirable dopability.…”
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Social justice and inequality in the mirror of public opinion: Dynamics and specifics by N. D. Kolennikova

“…Those Russians who consider their position in society to be low tend to perceive inequality more acutely, while the most advantaged groups show a rather tolerant attitude towards it. The author insists on the preservation of the request for improving the situation with social justice and reducing illegitimate inequalities, taking into account various interpretations of social justice in the Russian public consciousness. …”
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Association of FAS and FAS Ligand Genes Polymorphism and Risk of Systemic Lupus Erythematosus by Bita Moudi, Saeedeh Salimi, Farzaneh Farajian Mashhadi, Mahnaz Sandoughi, Zahra Zakeri

“…FAS/FASL pathway plays a critical role in maintaining peripheral immune tolerance; therefore, the apoptosis genes, Fas and Fas ligand (FasL), could be suitable candidate genes in human SLE susceptibility. …”
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Perspectives of pressurized intraperitoneal aerosol chemotherapy in terms of primary ovarian cancer with peritoneal carcinomatosis treatment by A. S. Dzasokhov, A. A. Kostin, V. L. Astashov, A. V. Turiev, A. D. Uskov

“…These advantages include the uniform distribution of cytostatics over the peritoneum, the absence of penetration of cytostatics beyond the peritoneum, which allows PIPAC to be combined with systemic chemotherapy, low trauma and good tolerability of the procedure. PIPAC was implemented into clinical practice in 2011, and since then has been widely used in a number of foreign and domestic clinics. …”
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Value of teff (Eragrostis tef) genetic resources to support breeding for conventional and smallholder farming: a review by Aemiro Bezabih Woldeyohannes, Ermias Abate Desta, Carlo Fadda, Mario Enrico Pè, Matteo Dell’Acqua

“…We collect data generated on the largest teff ex situ collections in the world to discuss opportunities to improve teff tolerance to stress and lodging, as well as to increase its productivity across its cropping area. …”
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The effect of high-sugar feeding on rodent metabolic phenotype: a systematic review and meta-analysis by Sophie Lucic Fisher, G. Jean Campbell, Alistair Senior, Kim Bell-Anderson

“…High-sugar feeding, with fructose in particular, altered liver phenotype; ALT (d = 1.08; 0.66, 1.5), triglyceride content (d = 0.52; 0.25, 0.78), cholesterol (d = 0.59; 0.16, 1.03) and liver mass (d = 0.93; 0.37, 1.48), and glucose tolerance; fasting glucose (d = 0.60; 0.18, 1.01) and fasting insulin (d = 0.42; 0.07, 0.77) but not body weight or energy intake. …”
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DREDGING IMPACT ON THE LAKE MANZHEROK (REPUBLIC OF ALTAY) HYDRO/ BIOLOGICAL AND SANITARY/MICRO/BIOLOGICAL CHARACTERISTICS by Dmitry M. Bezmaternykh, Vladimir V. Kirillov, Nadezhda I. Yermolaeva, Laura M. Kipryanova, Lyubov V. Yanygina, Elena Y. Mitrofanova, Olga N. Vdovina, Anton V. Kotovschikov, Evgeniya Y. Zarubina

“…The whole content of coliform bacteria in the off-shore zone 25 times exceeded the norm, while the content of thermo/tolerant coliform bacteria in the center of the lake and in the macrophytes tangle 2.3 times exceeded the norm.…”

Interactions among Zinc, Iron, and Paraquat in the Physiological and Toxicological Responses of the Egyptian Cotton Leafworm <i>Spodoptera littoralis</i> by Haq Abdul Shaik, David Siaussat, Archana Mishra

“…Agricultural pollutants co-interact and affect the vital functions, stress tolerance, resistance, immunity, and survival of insect pests. …”
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Optogenetic screening of MCT1 activity implicates a cluster of non-steroidal anti-inflammatory drugs (NSAIDs) as inhibitors of lactate transport. by Scott A Wegner, Hahn Kim, José L Avalos

“…Our findings show that several existing drug classes inhibit MCT1 activity, including non-steroidal estrogens, non-steroidal anti-inflammatory drugs (NSAIDs), and natural products (in total representing approximately 1% of the total library, 78 out of 6400), with a moderate affinity (IC50 1.8-21 μM). Given the well-tolerated nature of NSAIDs, and their known anticancer properties associated with COX inhibition, we chose to further investigate their MCT1 inhibition profile. …”
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The Effect of Medium Chain Triglycerides on Time to Nutritional Ketosis and Symptoms of Keto-Induction in Healthy Adults: A Randomised Controlled Clinical Trial by Cliff J. d C. Harvey, Grant M. Schofield, Micalla Williden, Joseph A. McQuillan

“…Medium chain triglycerides (MCTs) are ketogenic and might reduce adverse effects of keto-induction and improve time to ketosis and the tolerability of very low carbohydrate diets. This study investigates whether MCT supplementation improves time to nutritional ketosis (NK), mood, and symptoms of keto-induction. …”
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