Adjuvant Radiotherapy for Synchronous Bilateral Testicular Seminoma: A Case Report and a Review of the Pertinent Literature by Daniel A. Jones, Elizabeth C. Ester, David Leavitt, Robert Sweet, Badrinath Konety, Gautam Jha, L. Chinsoo Cho

“…Although morbidity associated with radiotherapy directed at the abdomen is not negligible, adjuvant paraaortic radiotherapy remains safe and well-tolerated treatment regime. Bilateral synchronous stage I seminoma of the testes is rare. …”
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IL-34 Suppresses Candida albicans Induced TNFα Production in M1 Macrophages by Downregulating Expression of Dectin-1 and TLR2 by Rong Xu, Hong-Fan Sun, David W. Williams, Adam V. Jones, Ali Al-Hussaini, Bing Song, Xiao-Qing Wei

“…Normally, C. albicans exists as a harmless commensal and does not trigger inflammatory responses by resident macrophages in skin mucosa, which may be caused by a tolerance of skin macrophage to C. albicans. IL-34 is a recently discovered cytokine, constitutively expressed by keratinocytes in the skin. …”
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Gossypol is a natural product with good antimalarial activity against Plasmodium falciparum clinical isolates by Jersley D. Chirawurah, Felix Ansah, Samuel Blankson, Bridget Adikah, Silas Nkansah Yeboah, Lucas Amenga-Etego, Gordon A. Awandare, Yaw Aniweh

“…Importantly, these gossypol-tolerant parasites showed no cross-resistance to chloroquine, DHA, or the three Malaria box compounds. …”
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Gestational Diabetes and Thyroid Autoimmunity by Ester Vitacolonna, Annunziata Lapolla, Barbara Di Nenno, Annalisa Passante, Ines Bucci, Cesidio Giuliani, Dominique Cerrone, Fabio Capani, Fabrizio Monaco, Giorgio Napolitano

“…We investigated 126 pregnant women at the time of a 100-g oral glucose tolerance test: 91 were classified as gestational diabetics, and 35 were negative (controls). …”
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Dopamine and 24-Epibrassinolide Upregulate Root Resilience, Mitigating Lead Stress on Leaf Tissue and Stomatal Performance in Tomato Plants by Lohana Ribeiro Prestes, Madson Mateus Santos da Silva, Sharon Graziela Alves da Silva, Maria Andressa Fernandes Gonçalves, Bruno Lemos Batista, Ivan Becari Viana, Allan Klynger da Silva Lobato

“…It is found in plant organs and induces tolerance against abiotic stresses, including contamination. 24-epibrassinolide (EBR) stimulates metabolism, positively impacting flowering and production. …”
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Real-world efficacy and safety of dupilumab in children with atopic dermatitis under 6 years of age: a retrospective multicentric study by Filip Rob, Blanka Pinkova, Kristyna Sokolova, Jana Kopuleta, Zuzana Jiraskova Zakostelska, Jana Cadova

“…In conclusion, dupilumab exhibited favorable tolerability, efficacy, and safety in children diagnosed with atopic dermatitis who were below the age of 6.…”
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Eficacia y seguridad del tratamiento con la combinación fija a dosis bajas de cinarizina 20 mg y dimenhidrinato 40 mg en el vértigo de origen diverso en la práctica clínica en Espa... by Rafael Hijano-Esqué, Jesús Ignacio González Orodea, Javier Imaz Fandos, Natividad Pacheco Rubio, Gonzalo Daniel Alzuarte, Manuel Ruiz Cuetos, Amelia Rodríguez Mariblanca, Eva García Aguilar

“…Additional outcomes such as speed of action, tolerability, and treatment satisfaction were also measured. …”
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A Retrospective Analysis of Self-Limiting Fever following Percutaneous Patent Foramen Ovale and Atrial Septal Defect Closure by Francesca Galasso, Felicia Wassenaar, Timothy Barry, Omar J. Baqal, Donald J. Hagler, John P. Sweeney, F. David Fortuin

“…While percutaneous closure of patent foramen ovale (PFO) and atrial septal defect (ASD) are generally well-tolerated procedures, the development of postprocedure fever has been observed at a higher frequency than reported in the initial device trials. …”
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Prevalence of Bullying among Primary School Pupils in Al-Najaf City, Iraq by Essam Abed AL-Shibli, maytham ALnasrawii

“…To address this, teachers should dedicate class time to discussing the harms of bullying and promote tolerance, while also supporting strategies to reduce school violence.…”
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UV-C light irradiation effects on two rose cultivars infected with Botrytis cinerea by Eduardo Espejel-Maycotte, Ma de Lourdes Arevalo-Galarza, Jose Alfredo Carrillo-Salazar, José Refugio Lomelí-Flores, Victoria Ayala-Escobar, Luis Francisco Salomé-Abarca

“…Proud had thicker abaxial and adaxial epidermis, with numerous elongated cone-shaped papillae, which may confer greater tolerance to Botrytis infections. …”
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Innovative immunotherapies and emerging treatments in type 1 diabetes management by Malek Zarei, Mohammad Abbas Sheikholeslami, Masoud Mozaffari, Yassar Mortada

“…Antigen-dependent strategies focus on inducing immune tolerance to specific beta cell antigens, with mixed results from clinical trials involving autoantigen vaccines like GAD65. …”
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Application of dicarbamin in treatment of patients by a chronic hepatitis C by D. Yu. Konstantinov, Ye. A. Konstantinova, L. L. Popova, E. A. Strebkova, A. A. Suzdaltsev

“…Application of dicarbamin at combined antiviral therapy of CHC results in elevation of leukocyte and neutrophile count in the blood and allows to carry out treatment without dose decline and cancellation of peginterferon. High tolerability of AVT in CHC patients at application of suggested mode of treatment (peginterferon α2b, ribavirin and dicarbamin) was revealed.…”
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Multifunctional probiotic and safety attributes Heyndrickxia coagulans isolated from stingless bee honey by Benyapa Prakit, Rungravee Chaiyod, Kittiya Khongkool, Wankuson Chanasit, Monthon Lertworapreecha

“…Results We isolated two novel H. coagulans, TBRC-18260 and TBRC-18261, and conducted comprehensive in vitro analyses to assess their probiotic traits such as acid and bile salt tolerance, self-aggregation, and pathogen inhibition. …”
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A Retrospective Patient Chart Review and Survey in Patients with Cryopyrin-associated Periodic Syndromes Treated with Anakinra by Helen J. Lachmann, Renée J.G. Arnold, Marco Gattorno, Isabelle Koné-Paut, Alberto Ferreira, Jasmin Kümmerle-Deschner

“…**Objectives:** The main study objective was to quantify the patients’ burden of disease in terms of flares and resource use and to characterize patient symptomatology and tolerability of treatment with anakinra. A secondary objective included comparing chart review and patient recall of symptoms and AEs. …”
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A Decision-Making Approach for Ranking Tertiary Institutions’ Service Quality Using Fuzzy MCDM and Extended HiEdQUAL Model by Olufunke Oladipupo, Taiwo Amoo, Olawande Daramola

“…Also, findings from the sensitivity analysis showed that Yager’s min-max outperform the other investigated methods in this study by being consistent and exceptionally tolerant in most instances when there is significant deviation in criteria weights.…”
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Assessment of Left Ventricular Reverse Remodeling by Echocardiography After 90 Days of Sacubitril/Valsartan Therapy in Patients of Heart Failure with Reduced Ejection Fraction by Akshay Pawar, Rajesh Rajani, Deepak Sadashiv Phalgune

“…Patients were given sacubitril/valsartan maximal tolerated dose. Echocardiographic measurements were done after 90 days. …”
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Natural history of the hyperdominant tree, Pentaclethra macroloba (Willd.) Kuntze, in the Amazon River estuary by A. R. Dantas, C. C. Vasconcelos, M. C. Guedes, A. C. Lira-Guedes, M. T. F. Piedade

“…Abstract Pentaclethra macroloba is a hyperdominant species with multiple uses in the Amazon. This species tolerates varying flood amplitudes, however the effect of flood topographic gradient on its ecophysiology remains unclear. …”
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Fludarabine/Cyclophosphamide Conditioning Regimen in Aplastic Anemia Patients Receiving Matched-Sibling Donor Transplant Is Non-inferior to ATG/Cyclophosphamide: A Single-Center Ex... by Uzma Zaidi, Mushkbar Fatima, Shafaq Abdul Samad, Kashif Shafique, Hira Fatima Waseem, Tasneem Farzana, Tahir Sultan Shamsi

“…The Flu/Cy regimen was well tolerated and was not associated with increased risk of GvHD. …”
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Combination of triciribine and p38 MAPK inhibitor PD169316 enhances the differentiation effect on myeloid leukemia cells. by Yuri Sato-Nagaoka, Susumu Suzuki, Souma Suzuki, Shinichiro Takahashi

“…However, the narrow application and tolerance development of ATRA remain to be improved. …”
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A metamodern model for managing stakeholder relationships in non-profit organisations by Irma Meyer, Rachel Barker

“…Modernists believe in a single truth, accept metanarratives and believe that grand theory represents knowledge and can explain everything, whilst postmodernists reject the absolute standards and grand theories typical of modernism in favour of awareness and tolerance of differences, ambiguity and conflict. This article links these two perspectives in a new metamodern model for stakeholder relationship management, aimed specifically at the South African non-profit sector. …”
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