Network modeling of problematic social media use components in college student social media users by Jianyong Chen, Jianyong Chen, Ting Su, Ting Su, Junqiang Dong, Yuzhi Li, Yuzhi Li, Ju Feng, Ju Feng, Yingxiu Chen, Yingxiu Chen, Gu Liu, Gu Liu

“…We computed two types of network models, Gaussian graphical models (GGMs) to examine network structure and influential nodes and directed acyclic graphs (DAGs) to identify the probabilistic dependencies among components.ResultRelapse component consistently emerged as a central node in the GGMs and as a parent node of other components in the DAGs. Relapse and tolerance components exhibited strong mutual connections and were linked to the most vital edges within the networks. …”
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Properties of Wood Powder Sheets Extruded with Hydroxypropyl Methylcellulose and Citric Acid after Heating by Hiroyuki Hiratsuka, Xiangyu Tao, Yuki Tokunaga, Hiroshi Nonaka

“…Water absorption, tensile strength, puncture resistance, and wettability were then tested. The sheet became tolerant of water and developed slightly higher tensile strength upon adequate heating, although it was more easily punctured when rewetted. …”
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Procyanidin A1 and its digestive products alleviate acrylamide-induced IPEC-J2 cell damage through regulating Keap1/Nrf2 pathway by Fangfang Yan, Qun Lu, Chengming Wang, Rui Liu

“…Importantly, there was no difference between A1 and D-A1 treated groups, indicating that A1 can tolerate gastrointestinal digestion and may be a potential compound to limit the toxicity of ACR.…”
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Phase I trial on the safety of olprinone for low central venous pressure management aimed at haemorrhage control during open and laparoscopic hepatectomy: a study protocol by Katsuhiko Uesaka, Yuya Miura, Teiichi Sugiura, Ryo Ashida, Katsuhisa Ohgi, Mihoko Yamada, Shimpei Otsuka, Yoshiyasu Kato, Takuya Oyakawa, Eiji Ando, Sunao Tamai

“…The trial employs a 3+3 cohort study design to determine the maximum tolerated dose (MTD) and identify dose-limiting toxicities. …”
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Clinical Trial of Human Fetal Brain-Derived Neural Stem/Progenitor Cell Transplantation in Patients with Traumatic Cervical Spinal Cord Injury by Ji Cheol Shin, Keung Nyun Kim, Jeehyun Yoo, Il-Sun Kim, Seokhwan Yun, Hyejin Lee, Kwangsoo Jung, Kyujin Hwang, Miri Kim, Il-Shin Lee, Jeong Eun Shin, Kook In Park

“…Therefore, the transplantation of hNSPCs into cervical SCI is safe and well-tolerated and is of modest neurological benefit up to 1 year after transplants. …”
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Temporal Trends and Spatial Patterns of Temperature and Its Extremes over the Beijing-Tianjin Sand Source Region (1960–2014), China by Wei Wei, Baitian Wang, Kebin Zhang, Zhongjie Shi, Genbatu Ge, Xiaohui Yang

“…As extreme low temperature events decrease, vegetation damage due to freezing temperatures will reduce and low cold-tolerant plants may expand their distribution range northward to revegetate barren areas in the BTSSR. …”
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Regulation of Shade Avoidance Under Low‐Blue‐Light by MTA in Soybean by Liya Zhang, Jun Liu, Jiaqi Chen, Yanyan Zhang, Chao Qin, Xiangguang Lyu, Zhuang Li, Ronghuan Ji, Bin Liu, Hongyu Li, Tao Zhao

“…The findings reveal a novel molecular mechanism regulating shade resistance in soybean, providing insights into the epigenetic mechanisms of plant adaptation to changing light environments and paving the way for the development of shade‐tolerant soybean varieties.…”
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Characterization of the ZDSD Rat: A Translational Model for the Study of Metabolic Syndrome and Type 2 Diabetes by Richard G. Peterson, Charles V. Jackson, Karen Zimmerman, Willem de Winter, Norman Huebert, Michael K. Hansen

“…As disease progressed to overt diabetes, ZDSD rats demonstrated elevated glucose levels, abnormal oral glucose tolerance, increases in HbA1c levels, reductions in body weight, increased insulin resistance with decreasing insulin levels, and dyslipidemia. …”
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The Effects of Baclofen for the Treatment of Gastroesophageal Reflux Disease: A Meta-Analysis of Randomized Controlled Trials by Shujie Li, Shengying Shi, Feng Chen, Jingming Lin

“…All reported side effects of baclofen were of mild-to-moderate intensity, and the drug was well tolerated. Conclusion. Abundant evidence suggests that baclofen may be a useful approach for the treatment of GERD patients; however, a larger well-designed research study would further confirm this recommendation.…”
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The results of orthotopic heart transplantation using the bicaval technique by B. M. Todurov, H. I. Kovtun, O. A. Loskutov, S. R. Maruniak, D. O. Loskutov, A. Yu. Melnyk

“…Heart transplantation increases the survival of patients with chronic heart failure, increases tolerance to physical exertion, improves the quality of life of patients and allows most of them to return to vigorous activity. …”
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Humic Acid Alleviates Low-Temperature Stress by Regulating Nitrogen Metabolism and Proline Synthesis in Melon (<i>Cucumis melo</i> L.) Seedlings by Libao Zhu, Haihe Liu, Yanping Zhang, Yanxia Cao, Yiwen Hu, Yalun Wang, Haiqiang Zheng, Mengze Liu

“…However, the effect of HA on the cold tolerance of melon plants under low-temperature scenarios is still unclear. …”
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The Impact of Creatine Supplementation on Physical Performance, Cognitive Functions, and Safety – A Literature Review by Adam Sobiński, Matylda Czerwonka, Zuzanna Kościuszko, Katarzyna Kurza, Silvia Ciraolo, Julianna Podolec, Agnieszka Kulczycka-Rowicka, Katarzyna Lesiczka-Fedoryj, Joanna Wojda, Anna Walczak

“…These findings support creatine as a versatile, well-tolerated dietary supplement for sports and health applications.   …”
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Efficacy of Anakinra for Various Types of Crystal-Induced Arthritis in Complex Hospitalized Patients: A Case Series and Review of the Literature by A. Aouba, S. Deshayes, L. Frenzel, A. Decottignies, C. Pressiat, B. Bienvenu, F. Boue, G. Damaj, O. Hermine, S. Georgin-Lavialle

“…Crowned dens syndrome patients, including two with pseudogout and one with subacute hydroxyapatite deposition disease, needed 9 to 11 days to achieve complete response. Tolerance to anakinra was good. Conclusion. In case series of complex hospitalized patients, anakinra showed good activity in crowned dens syndrome and associated crystal-induced peripheral arthritis, with longer treatment duration than in gouty arthritis.…”
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SCREENING FOR MAIZE RESISTANT GENOTYPES AGAINST STALK BORERS’ (Sesamia calamistis Hampson) INFESTATION IN MINNA, NIGER STATE, NIGERIA by Idowu, G.A., Oyewale, R.O., Jiboh, B.S., Bolajoko, M.H., Ibrahim, H.M., Bello, A.K

“…Therefore, MG-H and MG-S were recommended as tolerant maize genotypes while MG-C and MG-S were also recommended as high yielding maize genotypes among other genotypes under study.…”
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High Dose Ilaprazole/Amoxicillin as First-Line Regimen for Helicobacter pylori Infection in Korea by WonGun Kwack, YunJeong Lim, ChiYeon Lim, David Y. Graham

“…Compliance rates were high (96.6%) and side effects were minimal and tolerable. Conclusion. A high dose of ilaprazole + amoxicillin was ineffective as the first-line therapy for eradicating H. pylori in Korea. …”
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Efficacy of a “Rescue” Ciprofloxacin-Based Regimen for Eradication of Helicobacter pylori Infection after Treatment Failures by Maria Pina Dore, Vincenza Tadeu, Bianca Are, Ida Mura, Giuseppe Fanciulli, Giovannino Massarelli, Andrea Piana

“…The aim of our study was to evaluate the efficacy and tolerability of a ciprofloxacin-based regimen for H. pylori eradication failures as an alternative to bismuth based quadruple therapy. …”
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A Review of Perfluoroalkyl Acids (PFAAs) in terms of Sources, Applications, Human Exposure, Dietary Intake, Toxicity, Legal Regulation, and Methods of Determination by Katarzyna Sznajder-Katarzyńska, Magdalena Surma, Iwona Cieślik

“…As summarized in this study, PFAAs levels need further assessment due to the science-based TWI standards laid down by the EFSA’s CONTAM Panel regarding the risk to human health posed by the presence of perfluorooctane sulfonic acid and perfluorooctanoic acid in food (tolerable weekly intakes of PFOA and PFOS set up to 6 ng·kg−1·bw·week−1 and 13 ng·kg−1·bw·week−1, respectively). …”
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CHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair by Luc Provencher, Wilson Nartey, Peter M. Brownlee, Austin W. Atkins, Jean-Philippe Gagné, Lou Baudrier, Nicholas S. Y. Ting, Cortt G. Piett, Shujuan Fang, Dustin D. Pearson, Shaun Moore, Pierre Billon, Zachary D. Nagel, Guy G. Poirier, Gareth J. Williams, Aaron A. Goodarzi

“…Abstract To tolerate oxidative stress, cells enable DNA repair responses often sensitive to poly(ADP-ribose) (PAR) polymerase 1 and 2 (PARP1/2) inhibition—an intervention effective against cancers lacking BRCA1/2. …”
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The Effect of Goat Grazing on the Biodiversity of Pannonian Dry Grassland by Karoly Penksza, Ferenc Pajor, Andrea Kevi, Zsombor Wagenhoffer, Laszló Sipos, Eszter Salata-Falusi, Peter Penksza, Peter Poti, Jozsef Berke, Denes Salata, Marta Bajnok, Szilard Szentes

“…The overgrazed pasture (N1) exhibited the most degraded vegetation community, dominated by weeds and disturbance-tolerant species. The overgrazed (N1) pasture had a low forage value because of the different timing of treatments. …”
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Continuous Erector Spinae Plane Block for Analgesia after Thoracotomy for Lung Transplantation in an Anticoagulated Patient by Mark Mudarth, Veena Satyapriya, John Coffman, Peter DeSocio, Alec Lawrence, Shana Schwartz, Michael Kushelev

“…These approaches require a needle position in proximity to the neuraxis and may cause significant hypotension that is poorly tolerated in transplant patients. Additionally, the use of anticoagulation or underlying clotting disorder limits the use of these regional blocks because of the concern of hematoma and subsequent neurologic injury. …”
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